PL1828167T3 - Pochodne akryloamidu jako środki antybiotykowe - Google Patents
Pochodne akryloamidu jako środki antybiotykoweInfo
- Publication number
- PL1828167T3 PL1828167T3 PL05858503T PL05858503T PL1828167T3 PL 1828167 T3 PL1828167 T3 PL 1828167T3 PL 05858503 T PL05858503 T PL 05858503T PL 05858503 T PL05858503 T PL 05858503T PL 1828167 T3 PL1828167 T3 PL 1828167T3
- Authority
- PL
- Poland
- Prior art keywords
- antibiotic agents
- acrylamide derivatives
- acrylamide
- derivatives
- antibiotic
- Prior art date
Links
- 150000003926 acrylamides Chemical class 0.000 title 1
- 230000003115 biocidal effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57694504P | 2004-06-04 | 2004-06-04 | |
| EP05858503.5A EP1828167B1 (en) | 2004-06-04 | 2005-06-06 | Acrylamide derivatives as antibiotic agents |
| PCT/US2005/019805 WO2007053131A2 (en) | 2004-06-04 | 2005-06-06 | Acrylamide derivatives as antibiotic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1828167T3 true PL1828167T3 (pl) | 2015-02-27 |
Family
ID=37889654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05858503T PL1828167T3 (pl) | 2004-06-04 | 2005-06-06 | Pochodne akryloamidu jako środki antybiotykowe |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8450307B2 (pl) |
| EP (2) | EP2848614A3 (pl) |
| JP (1) | JP5087406B2 (pl) |
| KR (1) | KR101299399B1 (pl) |
| CA (1) | CA2568914C (pl) |
| CY (1) | CY1115713T1 (pl) |
| DK (1) | DK1828167T3 (pl) |
| ES (1) | ES2515101T3 (pl) |
| PL (1) | PL1828167T3 (pl) |
| PT (1) | PT1828167E (pl) |
| SI (1) | SI1828167T1 (pl) |
| WO (1) | WO2007053131A2 (pl) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU773218B2 (en) * | 1999-10-08 | 2004-05-20 | Debiopharm International Sa | Fab I inhibitors |
| EP1560584B1 (en) * | 2001-04-06 | 2009-01-14 | Affinium Pharmaceuticals, Inc. | Fab i inhibitors |
| WO2008009122A1 (en) | 2006-07-20 | 2008-01-24 | Affinium Pharmaceuticals, Inc. | Acrylamide derivatives as fab i inhibitors |
| EP3255045A1 (en) | 2007-02-16 | 2017-12-13 | Debiopharm International SA | Salts, prodrugs and polymorphs of fab i inhibitors |
| JP5745855B2 (ja) | 2007-11-28 | 2015-07-08 | セコイア、ファーマシューティカルズ、インコーポレイテッドＳｅｑｕｏｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | シトクロムｐ４５０ ２ｄ６を阻害するための組成物および方法 |
| WO2010089993A1 (ja) | 2009-02-03 | 2010-08-12 | クミアイ化学工業株式会社 | 縮合環化した２－ピリドン誘導体及び除草剤 |
| WO2011061214A1 (en) * | 2009-11-18 | 2011-05-26 | Fab Pharma Sas | Novel heterocyclic acrylamides and their use as pharmaceuticals |
| WO2011131748A2 (en) | 2010-04-21 | 2011-10-27 | Probiodrug Ag | Novel inhibitors |
| HUP1000598A2 (en) | 2010-11-05 | 2012-09-28 | Richter Gedeon Nyrt | Indole derivatives |
| BR112013011188B1 (pt) | 2010-11-05 | 2022-01-04 | Senomyx, Inc | Método não-médico para modular canal potencial de receptor transiente de melastina 8 (trpm8), método não-médico para modular a sensação de resfriamento de uma composição, método não-médico para induzir uma sensação de resfriamento em um humano ou animal e composto |
| CA2842526C (en) | 2011-08-10 | 2019-07-23 | Janssen R&D Ireland | Antibacterial homopiperidinyl substituted 3,4-dihydro-1h-[1,8]naphthyridinones |
| EA201490435A1 (ru) | 2011-08-10 | 2014-06-30 | ЯНССЕН Ар ЭНД Ди АЙРЛЭНД | Антибактериальные 3,4-дигидро-1н-[1,8]нафтиридиноны, замещенные пиперидинилом |
| JO3611B1 (ar) | 2011-08-10 | 2020-08-27 | Janssen Sciences Ireland Uc | سايكلو بنتا (سي (بيرول 4,3 ثاني هيدرو 1 hمستبدله [8,1] نافثيريدينونات مضادة للجراثيم |
| WO2013042035A1 (en) * | 2011-09-19 | 2013-03-28 | Vitas Pharma Research Private Limited | Heterocyclic compounds as inhibitors of fatty acid biosynthesis for bacterial infections |
| SMT201900411T1 (it) | 2012-06-19 | 2019-09-09 | Debiopharm Int Sa | Derivati di profaramci di (e)-n-metil-n-((3-metilbenzofuran-2-il)metil -3-(7-osso-5,6,7,8-tetraidro-1,8-naftiridin-3-il)acrilammide |
| KR102323873B1 (ko) * | 2012-08-10 | 2021-11-09 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | 신규한 항균성 화합물 |
| CN104781250B (zh) | 2012-08-10 | 2017-05-10 | 爱尔兰詹森科学公司 | 新型抗细菌化合物 |
| WO2014072930A2 (en) * | 2012-11-09 | 2014-05-15 | Aurigene Discovery Technologies Limited | Fused pyridine derivatives as antibacterial agents |
| MX389514B (es) | 2015-10-01 | 2025-03-20 | Firmenich Incorporated | Compuestos útiles como moduladores de canal receptor 8 de potencial transitorio de melastatina (trpm8). |
| SMT202000719T1 (it) | 2016-02-26 | 2021-03-15 | Debiopharm Int Sa | Medicinale per il trattamento d’infezioni del piede diabetico |
| DK3880675T3 (da) * | 2018-11-12 | 2024-12-02 | Debiopharm Int Sa | Antibiotiske forbindelser, fremgangsmåder til fremstilling deraf, farmaceutiske sammensætninger indeholdende disse og anvendelser deraf |
| HUE062061T2 (hu) | 2019-02-14 | 2023-09-28 | Debiopharm Int Sa | Afabicin készítmény, eljárás annak elõállítására |
| UA129222C2 (uk) | 2019-06-14 | 2025-02-12 | Дебіофарм Інтернешнл С.А. | Лікарський засіб і його застосування для лікування бактеріальних інфекцій, пов'язаних з біоплівкою |
| US10947253B2 (en) | 2019-08-05 | 2021-03-16 | Ankh Life Sciences Limited | Fused polycyclic dimers |
| CN115667216B (zh) * | 2020-04-07 | 2025-02-18 | 赛诺菲 | 用于治疗癌症的作为tead蛋白和hippo-yap1/taz信号传导级联抑制剂的(1h-吲哚-5-基)丙烯酰胺衍生物 |
| US20240239771A1 (en) * | 2020-05-29 | 2024-07-18 | Taxis Pharmaceuticals, Inc. | Bacterial efflux pump inhibitors |
| US12129265B2 (en) | 2020-07-21 | 2024-10-29 | Ankh Life Sciences Limited | Therapeutic agents and uses thereof |
| CN111991385A (zh) * | 2020-08-17 | 2020-11-27 | 暨南大学 | 棕榈油酸在抑制水产病原菌中的应用 |
| WO2022187329A1 (en) * | 2021-03-03 | 2022-09-09 | The Board Of Trustees Of The University Of Illinois | Fabi inhibitors for gram-negative pathogens |
| US12060148B2 (en) | 2022-08-16 | 2024-08-13 | Honeywell International Inc. | Ground resonance detection and warning system and method |
| WO2025073269A1 (zh) * | 2023-10-07 | 2025-04-10 | 广州白云山医药集团股份有限公司白云山制药总厂 | 一种FabI酶抑制剂及其应用 |
| WO2025078209A1 (en) * | 2023-10-09 | 2025-04-17 | Debiopharm International S.A. | Antibiotic compounds for treating bacterial infections |
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-
2005
- 2005-06-06 US US11/628,569 patent/US8450307B2/en not_active Expired - Fee Related
- 2005-06-06 PL PL05858503T patent/PL1828167T3/pl unknown
- 2005-06-06 EP EP14179596.3A patent/EP2848614A3/en not_active Withdrawn
- 2005-06-06 CA CA2568914A patent/CA2568914C/en not_active Expired - Fee Related
- 2005-06-06 KR KR1020077000169A patent/KR101299399B1/ko not_active Expired - Fee Related
- 2005-06-06 PT PT58585035T patent/PT1828167E/pt unknown
- 2005-06-06 JP JP2007543017A patent/JP5087406B2/ja not_active Expired - Fee Related
- 2005-06-06 ES ES05858503.5T patent/ES2515101T3/es not_active Expired - Lifetime
- 2005-06-06 SI SI200531900T patent/SI1828167T1/sl unknown
- 2005-06-06 DK DK05858503.5T patent/DK1828167T3/da active
- 2005-06-06 WO PCT/US2005/019805 patent/WO2007053131A2/en not_active Ceased
- 2005-06-06 EP EP05858503.5A patent/EP1828167B1/en not_active Expired - Lifetime
-
2013
- 2013-04-25 US US13/870,193 patent/US20140107106A1/en not_active Abandoned
-
2014
- 2014-10-31 CY CY20141100905T patent/CY1115713T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2848614A2 (en) | 2015-03-18 |
| EP2848614A3 (en) | 2015-07-29 |
| KR20080016517A (ko) | 2008-02-21 |
| EP1828167B1 (en) | 2014-08-06 |
| DK1828167T3 (da) | 2014-10-20 |
| US20100093705A1 (en) | 2010-04-15 |
| WO2007053131A2 (en) | 2007-05-10 |
| WO2007053131A3 (en) | 2007-08-02 |
| JP2008505194A (ja) | 2008-02-21 |
| ES2515101T3 (es) | 2014-10-29 |
| SI1828167T1 (sl) | 2014-12-31 |
| CA2568914A1 (en) | 2005-12-04 |
| PT1828167E (pt) | 2014-10-08 |
| KR101299399B1 (ko) | 2013-08-22 |
| CY1115713T1 (el) | 2017-01-25 |
| CA2568914C (en) | 2013-09-24 |
| US8450307B2 (en) | 2013-05-28 |
| EP1828167A2 (en) | 2007-09-05 |
| US20140107106A1 (en) | 2014-04-17 |
| JP5087406B2 (ja) | 2012-12-05 |
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