DE69727572D1 - Wässrige peptidzubereitung - Google Patents
Wässrige peptidzubereitungInfo
- Publication number
- DE69727572D1 DE69727572D1 DE69727572T DE69727572T DE69727572D1 DE 69727572 D1 DE69727572 D1 DE 69727572D1 DE 69727572 T DE69727572 T DE 69727572T DE 69727572 T DE69727572 T DE 69727572T DE 69727572 D1 DE69727572 D1 DE 69727572D1
- Authority
- DE
- Germany
- Prior art keywords
- peptide preparation
- aqueous peptide
- aqueous
- preparation
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2119996P | 1996-07-03 | 1996-07-03 | |
US21199P | 1996-07-03 | ||
PCT/US1997/010816 WO1998000157A1 (en) | 1996-07-03 | 1997-07-01 | Aqueous formulations of peptides |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69727572D1 true DE69727572D1 (de) | 2004-03-18 |
DE69727572T2 DE69727572T2 (de) | 2004-12-16 |
Family
ID=21802912
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69727572T Expired - Lifetime DE69727572T2 (de) | 1996-07-03 | 1997-07-01 | Wässrige peptidzubereitung |
Country Status (27)
Country | Link |
---|---|
US (2) | US5916582A (de) |
EP (1) | EP0909177B1 (de) |
JP (2) | JP2001504442A (de) |
CN (1) | CN1256146C (de) |
AR (1) | AR007715A1 (de) |
AT (1) | ATE259241T1 (de) |
AU (1) | AU3574897A (de) |
BR (1) | BR9710131A (de) |
CA (1) | CA2259505A1 (de) |
CO (1) | CO4890855A1 (de) |
CZ (1) | CZ298464B6 (de) |
DE (1) | DE69727572T2 (de) |
ES (1) | ES2213828T3 (de) |
HK (1) | HK1020677A1 (de) |
HU (1) | HU225691B1 (de) |
ID (1) | ID19305A (de) |
IL (1) | IL127770A (de) |
MY (1) | MY125556A (de) |
NO (1) | NO323296B1 (de) |
NZ (1) | NZ333579A (de) |
PL (1) | PL189403B1 (de) |
RO (1) | RO120611B1 (de) |
RU (1) | RU2201248C2 (de) |
SK (1) | SK284283B6 (de) |
TW (1) | TW586932B (de) |
WO (1) | WO1998000157A1 (de) |
ZA (1) | ZA975943B (de) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1716884T3 (en) | 1998-10-29 | 2014-03-10 | Medtronic Minimed Inc | reservoir Connection |
US6248093B1 (en) | 1998-10-29 | 2001-06-19 | Minimed Inc. | Compact pump drive system |
US7193521B2 (en) | 1998-10-29 | 2007-03-20 | Medtronic Minimed, Inc. | Method and apparatus for detecting errors, fluid pressure, and occlusions in an ambulatory infusion pump |
US6800071B1 (en) | 1998-10-29 | 2004-10-05 | Medtronic Minimed, Inc. | Fluid reservoir piston |
US20020173748A1 (en) | 1998-10-29 | 2002-11-21 | Mcconnell Susan | Reservoir connector |
US7919109B2 (en) | 1999-02-08 | 2011-04-05 | Intarcia Therapeutics, Inc. | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles |
US7258869B1 (en) | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
US8119159B2 (en) * | 1999-02-22 | 2012-02-21 | Merrion Research Iii Limited | Solid oral dosage form containing an enhancer |
US20070148228A1 (en) * | 1999-02-22 | 2007-06-28 | Merrion Research I Limited | Solid oral dosage form containing an enhancer |
US7658938B2 (en) * | 1999-02-22 | 2010-02-09 | Merrion Reasearch III Limited | Solid oral dosage form containing an enhancer |
US7063684B2 (en) | 1999-10-28 | 2006-06-20 | Medtronic Minimed, Inc. | Drive system seal |
CA2507524C (en) * | 2002-09-27 | 2012-12-11 | Zentaris Gmbh | Administration form for pharmaceutically active peptides with sustained release and method for the production thereof |
US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
US6984403B2 (en) * | 2003-12-04 | 2006-01-10 | Pfizer Inc. | Azithromycin dosage forms with reduced side effects |
US20060039949A1 (en) * | 2004-08-20 | 2006-02-23 | Nycz Jeffrey H | Acetabular cup with controlled release of an osteoinductive formulation |
US20060045902A1 (en) * | 2004-09-01 | 2006-03-02 | Serbousek Jon C | Polymeric wrap for in vivo delivery of osteoinductive formulations |
US20060057184A1 (en) * | 2004-09-16 | 2006-03-16 | Nycz Jeffrey H | Process to treat avascular necrosis (AVN) with osteoinductive materials |
EP1838290A2 (de) * | 2005-01-21 | 2007-10-03 | Alza Corporation | Therapeutische peptidformulierung zur beschichtung von mikronadeln mit erhöhter stabilität und mindestens einem gegenion |
US8137664B2 (en) * | 2005-02-02 | 2012-03-20 | Sdgi Holdings, Inc. | Method and kit for repairing a defect in bone |
US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
ES2365410T3 (es) * | 2005-04-08 | 2011-10-04 | Amylin Pharmaceuticals, Inc. | Formulaciones farmacéuticas que comprenden péptido de incretina y un disolvente polar aprótico. |
CN100336557C (zh) * | 2005-05-11 | 2007-09-12 | 北京双鹭药业股份有限公司 | 一种生长抑素的水溶液制剂、其制备方法及应用 |
US20060293243A1 (en) * | 2005-06-17 | 2006-12-28 | Navneet Puri | Stable, buffered, pharmaceutical compositions including motilin-like peptides |
US20060287243A1 (en) * | 2005-06-17 | 2006-12-21 | Navneet Puri | Stable pharmaceutical compositions including motilin-like peptides |
BRPI0710503A2 (pt) * | 2006-04-07 | 2011-08-16 | Merrion Res Iii Ltd | uso de uma composição farmacêutica, composição farmacêutica, e, forma de dosagem oral |
ES2351527T3 (es) | 2006-05-30 | 2011-02-07 | Intarcia Therapeutics, Inc | Modulador de flujo en dos piezas con conducto interno para un sistema osmótico de administración. |
NZ574524A (en) | 2006-08-09 | 2011-07-29 | Intarcia Therapeutics Inc | Piston assembly for positioning lumen of a reservoir for an osmotic delivery having a columnar body and a spring |
EP2157967B1 (de) | 2007-04-23 | 2013-01-16 | Intarcia Therapeutics, Inc | Suspensionsformulierungen insulinotroper peptide und ihre verwendung |
US8968786B2 (en) | 2007-06-22 | 2015-03-03 | Board Of Regents, The University Of Texas System | Formation of stable submicron peptide or protein particles by thin film freezing |
KR20100061486A (ko) * | 2007-09-11 | 2010-06-07 | 몬도바이오테크 래보래토리즈 아게 | 치료제로서의 펩티드의 용도 |
WO2009102467A2 (en) | 2008-02-13 | 2009-08-20 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
KR20110007242A (ko) * | 2008-05-07 | 2011-01-21 | 메리온 리서치 Ⅲ 리미티드 | 펩티드 조성물 및 그의 제조 방법 |
MX2020005326A (es) | 2008-08-15 | 2022-03-03 | Ironwood Pharmaceuticals Inc | Formulaciones que contienen linaclotida para administracion oral. |
JP5711138B2 (ja) | 2008-11-16 | 2015-04-30 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 高濃度の低粘度懸濁液 |
EP2400851A4 (de) * | 2009-02-25 | 2012-09-05 | Merrion Res Iii Ltd | Zusammensetzung und wirkstofffreisetzung von bisphosphonaten |
EP2246063A1 (de) * | 2009-04-29 | 2010-11-03 | Ipsen Pharma S.A.S. | GnRH Analoge enthaltende Retardformulierungen |
MX2012001660A (es) | 2009-08-06 | 2012-03-26 | Ironwood Pharmaceuticals Inc | Formulaciones que contienen linaclotida para adminstracion oral. |
LT2462246T (lt) | 2009-09-28 | 2017-11-27 | Intarcia Therapeutics, Inc | Esminio stacionaraus vaisto tiekimo greitas įgyvendinimas ir (arba) nutraukimas |
US20110182985A1 (en) * | 2010-01-28 | 2011-07-28 | Coughlan David C | Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof |
WO2011103311A2 (en) | 2010-02-17 | 2011-08-25 | Ironwood Pharmaceuticals, Inc | Treatments for gastrointestinal disorders |
WO2011120033A1 (en) * | 2010-03-26 | 2011-09-29 | Merrion Research Iii Limited | Pharmaceutical compositions of selective factor xa inhibitors for oral administration |
US20140005128A1 (en) | 2010-08-11 | 2014-01-02 | Forest Laboratories Holdings Limited | Treatments of gastrointestinal disorders |
WO2012094598A2 (en) | 2011-01-07 | 2012-07-12 | Merrion Research Iii Limited | Pharmaceutical compositions of iron for oral administration |
US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
EP2776055B1 (de) | 2011-08-17 | 2016-12-14 | Ironwood Pharmaceuticals, Inc. | Behandlungen für magen-darm-erkrankungen |
US10112987B2 (en) | 2012-01-09 | 2018-10-30 | Icb International, Inc. | Blood-brain barrier permeable peptide compositions comprising a vab domain of a camelid single domain heavy chain antibody against an amyloid-beta peptide |
US20140271923A1 (en) | 2013-03-14 | 2014-09-18 | Christopher Brian Reid | Compositions & formulations for preventing and treating chronic diseases that cluster in patients such as cardiovascular disease, diabetes, obesity, polycystic ovary syndrome, hyperlipidemia and hypertension, as well as for preventing and treating other diseases and conditions |
EP2832361A1 (de) * | 2013-07-29 | 2015-02-04 | Ipsen Pharma S.A.S. | Wässrige Zusammensetzungen mit verzögerter Freisetzung von LHRH-Analoga |
US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
CN107205948B (zh) | 2015-01-29 | 2021-12-14 | 诺和诺德股份有限公司 | 包含glp-1激动剂和肠溶衣的片剂 |
JP6993235B2 (ja) | 2015-06-03 | 2022-01-13 | インターシア セラピューティクス,インコーポレイティド | インプラントの設置及び撤去システム |
CN105749245A (zh) * | 2016-03-02 | 2016-07-13 | 张光泉 | 抗癌药醋酸地加瑞克注射液及其制备方法 |
EP3458084B1 (de) | 2016-05-16 | 2020-04-01 | Intarcia Therapeutics, Inc | Für den glucagonrezeptor selektive polypeptide und verfahren zu deren verwendung |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
KR20190104039A (ko) | 2017-01-03 | 2019-09-05 | 인타르시아 세라퓨틱스 인코포레이티드 | Glp-1 수용체 효능제의 연속적인 투여 및 약물의 동시-투여를 포함하는 방법 |
Family Cites Families (21)
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US3914412A (en) * | 1973-10-11 | 1975-10-21 | Abbott Lab | {8 Des{13 Gly{9 {0 10 -Gn{13 RH nonapeptide amide analogs in position 6 having ovulation-inducing activity |
US4248864A (en) * | 1979-08-30 | 1981-02-03 | American Home Products Corporation | Reproduction control |
JPH0625068B2 (ja) * | 1982-12-10 | 1994-04-06 | シンテツクス(ユ−・エス・エ−・)インコ−ポレイテイド | 鼻腔内投与用組成物及びその製造方法 |
US4547370A (en) * | 1983-11-29 | 1985-10-15 | The Salk Institute For Biological Studies | GnRH Antagonists |
US4661472A (en) * | 1985-05-09 | 1987-04-28 | The Salk Institute For Biological Studies | GnRH antagonists IX |
US4851385A (en) * | 1987-07-15 | 1989-07-25 | Indiana University Foundation | LHRH antagonist analogs having low histamine-release activity |
US4800191A (en) * | 1987-07-17 | 1989-01-24 | Schally Andrew Victor | LHRH antagonists |
DD273980B5 (de) * | 1988-07-12 | 1994-04-14 | Berlin Chemie Ag | Verfahren zur Herstellung von Insulin-Pr{paraten zur rektalen Anwendung |
US5034229A (en) * | 1988-12-13 | 1991-07-23 | Alza Corporation | Dispenser for increasing feed conversion of hog |
US5110596A (en) * | 1988-12-13 | 1992-05-05 | Alza Corporation | Delivery system comprising means for delivering agent to livestock |
US5057318A (en) * | 1988-12-13 | 1991-10-15 | Alza Corporation | Delivery system for beneficial agent over a broad range of rates |
DE4117507A1 (de) * | 1991-05-24 | 1992-11-26 | Schering Ag | Verfahren zur herstellung von n(pfeil hoch)6(pfeil hoch)-substituierten lysin-derivaten |
US5446025A (en) * | 1992-06-12 | 1995-08-29 | Abbott Laboratories | Formulations and method of the percutaneous administration of leuprolide |
TW333456B (en) * | 1992-12-07 | 1998-06-11 | Takeda Pharm Ind Co Ltd | A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide. |
JP3698721B2 (ja) * | 1993-02-23 | 2005-09-21 | ジェネンテク・インコーポレイテッド | 有機溶媒を用いて処理したポリペプチドの賦形剤安定化 |
DE4320201A1 (de) * | 1993-06-18 | 1995-01-12 | Asta Medica Ag | Verwendung von Cetrorelix und weiteren Nona- und Dekapeptiden zur Herstellung eines Arzneimittels zur Bekämpfung von Aids und zur Wachstumsstimulation |
HU221617B1 (hu) * | 1993-06-29 | 2002-12-28 | Ferring B.V. | Vizes készítmény dezmopresszin nazális adagolására |
US5482931A (en) * | 1993-06-29 | 1996-01-09 | Ferring Ab | Stabilized pharmaceutical peptide compositions |
US5413990A (en) * | 1993-08-06 | 1995-05-09 | Tap Pharmaceuticals Inc. | N-terminus modified analogs of LHRH |
US5595760A (en) * | 1994-09-02 | 1997-01-21 | Delab | Sustained release of peptides from pharmaceutical compositions |
WO1997027840A1 (en) * | 1996-02-02 | 1997-08-07 | Alza Corporation | Sustained delivery of an active agent using an implantable system |
-
1997
- 1997-06-13 US US08/874,694 patent/US5916582A/en not_active Expired - Lifetime
- 1997-06-28 MY MYPI97002941A patent/MY125556A/en unknown
- 1997-07-01 DE DE69727572T patent/DE69727572T2/de not_active Expired - Lifetime
- 1997-07-01 AU AU35748/97A patent/AU3574897A/en not_active Abandoned
- 1997-07-01 WO PCT/US1997/010816 patent/WO1998000157A1/en active IP Right Grant
- 1997-07-01 CZ CZ0433998A patent/CZ298464B6/cs not_active IP Right Cessation
- 1997-07-01 IL IL127770A patent/IL127770A/en not_active IP Right Cessation
- 1997-07-01 CA CA002259505A patent/CA2259505A1/en not_active Abandoned
- 1997-07-01 CN CNB971960526A patent/CN1256146C/zh not_active Expired - Fee Related
- 1997-07-01 JP JP50421998A patent/JP2001504442A/ja not_active Ceased
- 1997-07-01 ES ES97932237T patent/ES2213828T3/es not_active Expired - Lifetime
- 1997-07-01 EP EP97932237A patent/EP0909177B1/de not_active Expired - Lifetime
- 1997-07-01 RO RO98-01770A patent/RO120611B1/ro unknown
- 1997-07-01 HU HU0000589A patent/HU225691B1/hu not_active IP Right Cessation
- 1997-07-01 BR BR9710131A patent/BR9710131A/pt not_active Application Discontinuation
- 1997-07-01 AT AT97932237T patent/ATE259241T1/de not_active IP Right Cessation
- 1997-07-01 NZ NZ333579A patent/NZ333579A/en not_active IP Right Cessation
- 1997-07-01 RU RU99102246/14A patent/RU2201248C2/ru not_active IP Right Cessation
- 1997-07-01 PL PL97330903A patent/PL189403B1/pl not_active IP Right Cessation
- 1997-07-01 SK SK1798-98A patent/SK284283B6/sk not_active IP Right Cessation
- 1997-07-02 AR ARP970102966A patent/AR007715A1/es unknown
- 1997-07-03 CO CO97037100A patent/CO4890855A1/es unknown
- 1997-07-03 ID IDP972313A patent/ID19305A/id unknown
- 1997-07-03 ZA ZA9705943A patent/ZA975943B/xx unknown
- 1997-08-22 TW TW086109391A patent/TW586932B/zh active
-
1998
- 1998-12-30 NO NO19986208A patent/NO323296B1/no not_active IP Right Cessation
-
1999
- 1999-02-11 US US09/248,286 patent/US6068850A/en not_active Expired - Lifetime
- 1999-12-09 HK HK99105751A patent/HK1020677A1/xx not_active IP Right Cessation
-
2008
- 2008-06-25 JP JP2008165927A patent/JP2008291037A/ja active Pending
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |