HUP0000589A2 - Vizes peptid készítmények - Google Patents

Vizes peptid készítmények

Info

Publication number
HUP0000589A2
HUP0000589A2 HU0000589A HUP0000589A HUP0000589A2 HU P0000589 A2 HUP0000589 A2 HU P0000589A2 HU 0000589 A HU0000589 A HU 0000589A HU P0000589 A HUP0000589 A HU P0000589A HU P0000589 A2 HUP0000589 A2 HU P0000589A2
Authority
HU
Hungary
Prior art keywords
peptides
preparations
aqueous formulations
peptide compound
stable
Prior art date
Application number
HU0000589A
Other languages
English (en)
Inventor
James B. Eckenhoff
Joe Leonard
Steven J. Prestrelski
Cynthia L. Stevenson
Sally A. Tao
Jeremy C. Wright
Original Assignee
Alza Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corporation filed Critical Alza Corporation
Publication of HUP0000589A2 publication Critical patent/HUP0000589A2/hu
Publication of HUP0000589A3 publication Critical patent/HUP0000589A3/hu
Publication of HU225691B1 publication Critical patent/HU225691B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids

Abstract

A találmány tárgya peptidrőkőn vegyületet tartalmazó stabil vizeskészítmények, amelyek a következőkből állnak: a) legalább körülbelül10% legalább egy peptidvegyület; és b) víz, és az ilyen készítmény 37řC-őn legalább 3 hónapig stabil. A készítmények példáűl implantálhatóhatóanyagleadó eszközökben használhatók. A találmány a készítményekelőállítására szőlgáló eljárásra és a készítmények alkalmazására isvőnatkőzik. ŕ
HU0000589A 1996-07-03 1997-07-01 Aqueous formulations of peptides HU225691B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2119996P 1996-07-03 1996-07-03
PCT/US1997/010816 WO1998000157A1 (en) 1996-07-03 1997-07-01 Aqueous formulations of peptides

Publications (3)

Publication Number Publication Date
HUP0000589A2 true HUP0000589A2 (hu) 2000-09-28
HUP0000589A3 HUP0000589A3 (en) 2001-04-28
HU225691B1 HU225691B1 (en) 2007-06-28

Family

ID=21802912

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0000589A HU225691B1 (en) 1996-07-03 1997-07-01 Aqueous formulations of peptides

Country Status (27)

Country Link
US (2) US5916582A (hu)
EP (1) EP0909177B1 (hu)
JP (2) JP2001504442A (hu)
CN (1) CN1256146C (hu)
AR (1) AR007715A1 (hu)
AT (1) ATE259241T1 (hu)
AU (1) AU3574897A (hu)
BR (1) BR9710131A (hu)
CA (1) CA2259505A1 (hu)
CO (1) CO4890855A1 (hu)
CZ (1) CZ298464B6 (hu)
DE (1) DE69727572T2 (hu)
ES (1) ES2213828T3 (hu)
HK (1) HK1020677A1 (hu)
HU (1) HU225691B1 (hu)
ID (1) ID19305A (hu)
IL (1) IL127770A (hu)
MY (1) MY125556A (hu)
NO (1) NO323296B1 (hu)
NZ (1) NZ333579A (hu)
PL (1) PL189403B1 (hu)
RO (1) RO120611B1 (hu)
RU (1) RU2201248C2 (hu)
SK (1) SK284283B6 (hu)
TW (1) TW586932B (hu)
WO (1) WO1998000157A1 (hu)
ZA (1) ZA975943B (hu)

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Also Published As

Publication number Publication date
ZA975943B (en) 1998-04-16
HUP0000589A3 (en) 2001-04-28
IL127770A (en) 2006-10-31
DE69727572D1 (de) 2004-03-18
ATE259241T1 (de) 2004-02-15
MY125556A (en) 2006-08-30
WO1998000157A1 (en) 1998-01-08
EP0909177B1 (en) 2004-02-11
EP0909177A1 (en) 1999-04-21
NO323296B1 (no) 2007-03-05
HK1020677A1 (en) 2000-05-19
CA2259505A1 (en) 1998-01-08
JP2008291037A (ja) 2008-12-04
PL330903A1 (en) 1999-06-07
JP2001504442A (ja) 2001-04-03
NZ333579A (en) 2000-06-23
ID19305A (id) 1998-07-02
RU2201248C2 (ru) 2003-03-27
NO986208L (no) 1998-12-30
CZ433998A3 (cs) 1999-04-14
BR9710131A (pt) 1999-08-10
CN1224357A (zh) 1999-07-28
US5916582A (en) 1999-06-29
CN1256146C (zh) 2006-05-17
DE69727572T2 (de) 2004-12-16
ES2213828T3 (es) 2004-09-01
SK179898A3 (en) 1999-06-11
AU3574897A (en) 1998-01-21
IL127770A0 (en) 1999-10-28
US6068850A (en) 2000-05-30
PL189403B1 (pl) 2005-08-31
SK284283B6 (sk) 2005-01-03
NO986208D0 (no) 1998-12-30
CO4890855A1 (es) 2000-02-28
HU225691B1 (en) 2007-06-28
TW586932B (en) 2004-05-11
AR007715A1 (es) 1999-11-10
RO120611B1 (ro) 2006-05-30
CZ298464B6 (cs) 2007-10-10

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