DE69722793T2 - Squalamin in kombination mit anderen antikrebs-mittelen zur behandlung von tumoren - Google Patents
Squalamin in kombination mit anderen antikrebs-mittelen zur behandlung von tumoren Download PDFInfo
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- DE69722793T2 DE69722793T2 DE69722793T DE69722793T DE69722793T2 DE 69722793 T2 DE69722793 T2 DE 69722793T2 DE 69722793 T DE69722793 T DE 69722793T DE 69722793 T DE69722793 T DE 69722793T DE 69722793 T2 DE69722793 T2 DE 69722793T2
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- squalamine
- tumor
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Public Health (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US1638796P | 1996-04-26 | 1996-04-26 | |
| US16387P | 1996-04-26 | ||
| PCT/US1997/007011 WO1997040835A1 (en) | 1996-04-26 | 1997-04-25 | Treatment of carcinomas using squalamine in combination with other anti-cancer agents |
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| DE69722793D1 DE69722793D1 (de) | 2003-07-17 |
| DE69722793T2 true DE69722793T2 (de) | 2004-05-19 |
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| DE69722793T Expired - Lifetime DE69722793T2 (de) | 1996-04-26 | 1997-04-25 | Squalamin in kombination mit anderen antikrebs-mittelen zur behandlung von tumoren |
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| EP (1) | EP0910382B1 (enExample) |
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| AU (1) | AU735884B2 (enExample) |
| CA (1) | CA2252584C (enExample) |
| DE (1) | DE69722793T2 (enExample) |
| DK (1) | DK0910382T3 (enExample) |
| ES (1) | ES2201296T3 (enExample) |
| PT (1) | PT910382E (enExample) |
| WO (1) | WO1997040835A1 (enExample) |
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| US5847172A (en) * | 1995-06-07 | 1998-12-08 | Magainin Pharmaceuticals Inc. | Certain aminosterol compounds and pharmaceutical compositions including these compounds |
| WO2000009137A2 (en) * | 1998-08-12 | 2000-02-24 | Magainin Pharmaceuticals, Inc. | Aminosterol compounds and uses thereof |
| JP2002524481A (ja) * | 1998-09-10 | 2002-08-06 | ジェネーラ・コーポレーション | 他の抗癌剤または理学療法と組み合わせたスクアラミンを使用する癌腫の処置 |
| HU229520B1 (en) * | 1999-02-12 | 2014-01-28 | Scripps Research Inst | Methods for treatment of tumors and metastases using a combination of anti-angiogenic and immuno therapies |
| US7820718B1 (en) | 1999-04-07 | 2010-10-26 | Roger Williams Hospital | Combinations of ceramide and chemotherapeutic agents for inducing cell death and uses thereof in treating cancer |
| KR20030011106A (ko) * | 2000-06-23 | 2003-02-06 | 미쯔비시 웰 파마 가부시키가이샤 | 항종양 작용 강화제 |
| US20020073441A1 (en) | 2000-12-13 | 2002-06-13 | Ross Brian D. | Compositions and methods for detecting proteolytic activity |
| US20030059375A1 (en) * | 2001-08-20 | 2003-03-27 | Transave, Inc. | Method for treating lung cancers |
| WO2003015521A1 (en) * | 2001-08-20 | 2003-02-27 | Transave, Inc. | Treatment of cancers by inhalation of stable platinum-containing formulations |
| GB0126879D0 (en) * | 2001-11-08 | 2002-01-02 | Astrazeneca Ab | Combination therapy |
| JP2005530704A (ja) * | 2002-03-05 | 2005-10-13 | トランセイブ， インク． | 細胞内感染を予防及び治療するための吸入システム |
| CN1681478A (zh) * | 2002-08-02 | 2005-10-12 | 川塞夫有限公司 | 铂聚集体及其制备方法 |
| US9186322B2 (en) * | 2002-08-02 | 2015-11-17 | Insmed Incorporated | Platinum aggregates and process for producing the same |
| KR101301653B1 (ko) * | 2002-10-29 | 2013-08-30 | 트랜세이브, 인코포레이티드 | 항감염제의 지속적인 방출 |
| US7718189B2 (en) | 2002-10-29 | 2010-05-18 | Transave, Inc. | Sustained release of antiinfectives |
| US7879351B2 (en) * | 2002-10-29 | 2011-02-01 | Transave, Inc. | High delivery rates for lipid based drug formulations, and methods of treatment thereof |
| US20080194019A1 (en) * | 2003-09-09 | 2008-08-14 | Beth Israel Deaconess Medical Center, Inc. | Tumor Suppressor Lkb1 Kinase Directly Activates Amp-Activated Kinase |
| US20070053845A1 (en) * | 2004-03-02 | 2007-03-08 | Shiladitya Sengupta | Nanocell drug delivery system |
| AU2005219413A1 (en) * | 2004-03-02 | 2005-09-15 | Massachusetts Institute Of Technology | Nanocell drug delivery system |
| WO2005089448A2 (en) * | 2004-03-18 | 2005-09-29 | Transave, Inc. | Administration of cisplatin by inhalation |
| JP2008500397A (ja) * | 2004-05-21 | 2008-01-10 | トランセイブ， インク． | 肺疾患及び前肺疾患状態の治療 |
| JP2008514726A (ja) * | 2004-09-30 | 2008-05-08 | ザ ユニヴァーシティー オヴ シカゴ | ヘッジホッグ阻害剤、放射線及び化学療法薬の併用療法 |
| US20060246124A1 (en) * | 2004-11-08 | 2006-11-02 | Pilkiewicz Frank G | Methods of treating cancer with lipid-based platinum compound formulations administered intraperitoneally |
| EP1861072A2 (en) * | 2005-03-14 | 2007-12-05 | Massachusetts Institute Of Technology | Nanocells for diagnosis and treatment of diseases and disorders |
| JP2008539243A (ja) | 2005-04-25 | 2008-11-13 | ジェネーラ・コーポレーション | スクアラミンジラクテートの多形塩形態および無定形塩形態 |
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1997
- 1997-04-25 CA CA002252584A patent/CA2252584C/en not_active Expired - Lifetime
- 1997-04-25 WO PCT/US1997/007011 patent/WO1997040835A1/en not_active Ceased
- 1997-04-25 US US08/840,706 patent/US6147060A/en not_active Expired - Lifetime
- 1997-04-25 AU AU27441/97A patent/AU735884B2/en not_active Ceased
- 1997-04-25 PT PT97921396T patent/PT910382E/pt unknown
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- 1997-04-25 DE DE69722793T patent/DE69722793T2/de not_active Expired - Lifetime
- 1997-04-25 EP EP97921396A patent/EP0910382B1/en not_active Expired - Lifetime
- 1997-04-25 JP JP09539076A patent/JP2000510460A/ja active Pending
- 1997-04-25 AT AT97921396T patent/ATE242635T1/de not_active IP Right Cessation
- 1997-04-25 ES ES97921396T patent/ES2201296T3/es not_active Expired - Lifetime
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|---|---|
| US6147060A (en) | 2000-11-14 |
| PT910382E (pt) | 2003-10-31 |
| EP0910382A1 (en) | 1999-04-28 |
| CA2252584A1 (en) | 1997-11-06 |
| EP0910382B1 (en) | 2003-06-11 |
| AU735884B2 (en) | 2001-07-19 |
| ATE242635T1 (de) | 2003-06-15 |
| ES2201296T3 (es) | 2004-03-16 |
| AU2744197A (en) | 1997-11-19 |
| DK0910382T3 (da) | 2003-10-06 |
| WO1997040835A1 (en) | 1997-11-06 |
| DE69722793D1 (de) | 2003-07-17 |
| CA2252584C (en) | 2008-06-10 |
| JP2000510460A (ja) | 2000-08-15 |
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