CA2252584C - Treatment of carcinomas using squalamine in combination with other anti-cancer agents - Google Patents

Treatment of carcinomas using squalamine in combination with other anti-cancer agents Download PDF

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Publication number
CA2252584C
CA2252584C CA002252584A CA2252584A CA2252584C CA 2252584 C CA2252584 C CA 2252584C CA 002252584 A CA002252584 A CA 002252584A CA 2252584 A CA2252584 A CA 2252584A CA 2252584 C CA2252584 C CA 2252584C
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Canada
Prior art keywords
squalamine
tumor
treatment
pharmaceutical compositions
compositions according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002252584A
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English (en)
French (fr)
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CA2252584A1 (en
Inventor
Michael Zasloff
Jon Williams
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Genaera Corp
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Genaera Corp
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Publication of CA2252584A1 publication Critical patent/CA2252584A1/en
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Publication of CA2252584C publication Critical patent/CA2252584C/en
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Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002252584A 1996-04-26 1997-04-25 Treatment of carcinomas using squalamine in combination with other anti-cancer agents Expired - Lifetime CA2252584C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1638796P 1996-04-26 1996-04-26
US60/016,387 1996-04-26
PCT/US1997/007011 WO1997040835A1 (en) 1996-04-26 1997-04-25 Treatment of carcinomas using squalamine in combination with other anti-cancer agents

Publications (2)

Publication Number Publication Date
CA2252584A1 CA2252584A1 (en) 1997-11-06
CA2252584C true CA2252584C (en) 2008-06-10

Family

ID=21776862

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002252584A Expired - Lifetime CA2252584C (en) 1996-04-26 1997-04-25 Treatment of carcinomas using squalamine in combination with other anti-cancer agents

Country Status (11)

Country Link
US (1) US6147060A (enExample)
EP (1) EP0910382B1 (enExample)
JP (1) JP2000510460A (enExample)
AT (1) ATE242635T1 (enExample)
AU (1) AU735884B2 (enExample)
CA (1) CA2252584C (enExample)
DE (1) DE69722793T2 (enExample)
DK (1) DK0910382T3 (enExample)
ES (1) ES2201296T3 (enExample)
PT (1) PT910382E (enExample)
WO (1) WO1997040835A1 (enExample)

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RU2365370C1 (ru) * 2008-04-29 2009-08-27 Государственное учреждение Российский онкологический научный центр им. Н.Н. Блохина РАМН Способ лечения рака легкого
RU2367436C1 (ru) * 2008-05-26 2009-09-20 Государственное учреждение Российский онкологический научный центр им. Н.Н. Блохина РАМН Способ лечения рака легкого
RU2388503C1 (ru) * 2008-08-14 2010-05-10 Федеральное государственное учреждение "Ростовский научно-исследовательский онкологический институт Росмедтехнологий" Способ лечения рака легкого
RU2402280C2 (ru) * 2008-12-01 2010-10-27 Федеральное государственное учреждение "Российский научно-исследовательский онкологический институт Росмедтехнологий" Способ прогнозирования церебральных метастазов рака легкого
RU2406452C1 (ru) * 2009-06-22 2010-12-20 Федеральное государственное учреждение "Ростовский научно-исследовательский онкологический институт Росмедтехнологий" Способ лечения рака легкого
RU2411018C1 (ru) * 2009-12-22 2011-02-10 Государственное образовательное учреждение высшего профессионального образования "БАШКИРСКИЙ ГОСУДАРСТВЕННЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ФЕДЕРАЛЬНОГО АГЕНТСТВА ПО ЗДРАВООХРАНЕНИЮ И СОЦИАЛЬНОМУ РАЗВИТИЮ" Способ локальной химиотерапии метастазов в печень
RU2414894C1 (ru) * 2009-06-29 2011-03-27 Учреждение Российской академии медицинских наук Российский онкологический научный центр имени Н.Н. Блохина РАМН Способ лечения рака легкого
RU2429842C1 (ru) * 2010-06-15 2011-09-27 Учреждение Российской академии медицинских наук Научно-исследовательский институт онкологии Сибирского отделения Российской академии медицинских наук (НИИ онкологии СО РАМН) Способ профилактики послеоперационных осложнений при комбинированном лечении больных немелкоклеточным раком легкого iii стадии

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RU2365370C1 (ru) * 2008-04-29 2009-08-27 Государственное учреждение Российский онкологический научный центр им. Н.Н. Блохина РАМН Способ лечения рака легкого
RU2367436C1 (ru) * 2008-05-26 2009-09-20 Государственное учреждение Российский онкологический научный центр им. Н.Н. Блохина РАМН Способ лечения рака легкого
RU2388503C1 (ru) * 2008-08-14 2010-05-10 Федеральное государственное учреждение "Ростовский научно-исследовательский онкологический институт Росмедтехнологий" Способ лечения рака легкого
RU2402280C2 (ru) * 2008-12-01 2010-10-27 Федеральное государственное учреждение "Российский научно-исследовательский онкологический институт Росмедтехнологий" Способ прогнозирования церебральных метастазов рака легкого
RU2406452C1 (ru) * 2009-06-22 2010-12-20 Федеральное государственное учреждение "Ростовский научно-исследовательский онкологический институт Росмедтехнологий" Способ лечения рака легкого
RU2414894C1 (ru) * 2009-06-29 2011-03-27 Учреждение Российской академии медицинских наук Российский онкологический научный центр имени Н.Н. Блохина РАМН Способ лечения рака легкого
RU2411018C1 (ru) * 2009-12-22 2011-02-10 Государственное образовательное учреждение высшего профессионального образования "БАШКИРСКИЙ ГОСУДАРСТВЕННЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ФЕДЕРАЛЬНОГО АГЕНТСТВА ПО ЗДРАВООХРАНЕНИЮ И СОЦИАЛЬНОМУ РАЗВИТИЮ" Способ локальной химиотерапии метастазов в печень
RU2429842C1 (ru) * 2010-06-15 2011-09-27 Учреждение Российской академии медицинских наук Научно-исследовательский институт онкологии Сибирского отделения Российской академии медицинских наук (НИИ онкологии СО РАМН) Способ профилактики послеоперационных осложнений при комбинированном лечении больных немелкоклеточным раком легкого iii стадии

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US6147060A (en) 2000-11-14
CA2252584A1 (en) 1997-11-06
DE69722793T2 (de) 2004-05-19
ATE242635T1 (de) 2003-06-15
AU735884B2 (en) 2001-07-19
DE69722793D1 (de) 2003-07-17
WO1997040835A1 (en) 1997-11-06
AU2744197A (en) 1997-11-19
EP0910382A1 (en) 1999-04-28
JP2000510460A (ja) 2000-08-15
EP0910382B1 (en) 2003-06-11

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