JP2000510460A - スクアラミンを他の抗癌剤と併用する上皮性悪性腫瘍の治療 - Google Patents
スクアラミンを他の抗癌剤と併用する上皮性悪性腫瘍の治療Info
- Publication number
- JP2000510460A JP2000510460A JP09539076A JP53907697A JP2000510460A JP 2000510460 A JP2000510460 A JP 2000510460A JP 09539076 A JP09539076 A JP 09539076A JP 53907697 A JP53907697 A JP 53907697A JP 2000510460 A JP2000510460 A JP 2000510460A
- Authority
- JP
- Japan
- Prior art keywords
- squalamine
- treatment
- tumor
- cytotoxic compound
- cytotoxic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| PCT/US1997/007011 WO1997040835A1 (en) | 1996-04-26 | 1997-04-25 | Treatment of carcinomas using squalamine in combination with other anti-cancer agents |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2008514726A (ja) * | 2004-09-30 | 2008-05-08 | ザ ユニヴァーシティー オヴ シカゴ | ヘッジホッグ阻害剤、放射線及び化学療法薬の併用療法 |
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| US5847172A (en) * | 1995-06-07 | 1998-12-08 | Magainin Pharmaceuticals Inc. | Certain aminosterol compounds and pharmaceutical compositions including these compounds |
| WO2000009137A2 (en) * | 1998-08-12 | 2000-02-24 | Magainin Pharmaceuticals, Inc. | Aminosterol compounds and uses thereof |
| JP2002524481A (ja) * | 1998-09-10 | 2002-08-06 | ジェネーラ・コーポレーション | 他の抗癌剤または理学療法と組み合わせたスクアラミンを使用する癌腫の処置 |
| HU229520B1 (en) * | 1999-02-12 | 2014-01-28 | Scripps Research Inst | Methods for treatment of tumors and metastases using a combination of anti-angiogenic and immuno therapies |
| US7820718B1 (en) | 1999-04-07 | 2010-10-26 | Roger Williams Hospital | Combinations of ceramide and chemotherapeutic agents for inducing cell death and uses thereof in treating cancer |
| KR20030011106A (ko) * | 2000-06-23 | 2003-02-06 | 미쯔비시 웰 파마 가부시키가이샤 | 항종양 작용 강화제 |
| US20020073441A1 (en) | 2000-12-13 | 2002-06-13 | Ross Brian D. | Compositions and methods for detecting proteolytic activity |
| US20030059375A1 (en) * | 2001-08-20 | 2003-03-27 | Transave, Inc. | Method for treating lung cancers |
| WO2003015521A1 (en) * | 2001-08-20 | 2003-02-27 | Transave, Inc. | Treatment of cancers by inhalation of stable platinum-containing formulations |
| GB0126879D0 (en) * | 2001-11-08 | 2002-01-02 | Astrazeneca Ab | Combination therapy |
| JP2005530704A (ja) * | 2002-03-05 | 2005-10-13 | トランセイブ， インク． | 細胞内感染を予防及び治療するための吸入システム |
| CN1681478A (zh) * | 2002-08-02 | 2005-10-12 | 川塞夫有限公司 | 铂聚集体及其制备方法 |
| US9186322B2 (en) * | 2002-08-02 | 2015-11-17 | Insmed Incorporated | Platinum aggregates and process for producing the same |
| KR101301653B1 (ko) * | 2002-10-29 | 2013-08-30 | 트랜세이브, 인코포레이티드 | 항감염제의 지속적인 방출 |
| US7718189B2 (en) | 2002-10-29 | 2010-05-18 | Transave, Inc. | Sustained release of antiinfectives |
| US7879351B2 (en) * | 2002-10-29 | 2011-02-01 | Transave, Inc. | High delivery rates for lipid based drug formulations, and methods of treatment thereof |
| US20080194019A1 (en) * | 2003-09-09 | 2008-08-14 | Beth Israel Deaconess Medical Center, Inc. | Tumor Suppressor Lkb1 Kinase Directly Activates Amp-Activated Kinase |
| US20070053845A1 (en) * | 2004-03-02 | 2007-03-08 | Shiladitya Sengupta | Nanocell drug delivery system |
| AU2005219413A1 (en) * | 2004-03-02 | 2005-09-15 | Massachusetts Institute Of Technology | Nanocell drug delivery system |
| WO2005089448A2 (en) * | 2004-03-18 | 2005-09-29 | Transave, Inc. | Administration of cisplatin by inhalation |
| JP2008500397A (ja) * | 2004-05-21 | 2008-01-10 | トランセイブ， インク． | 肺疾患及び前肺疾患状態の治療 |
| US20060246124A1 (en) * | 2004-11-08 | 2006-11-02 | Pilkiewicz Frank G | Methods of treating cancer with lipid-based platinum compound formulations administered intraperitoneally |
| EP1861072A2 (en) * | 2005-03-14 | 2007-12-05 | Massachusetts Institute Of Technology | Nanocells for diagnosis and treatment of diseases and disorders |
| JP2008539243A (ja) | 2005-04-25 | 2008-11-13 | ジェネーラ・コーポレーション | スクアラミンジラクテートの多形塩形態および無定形塩形態 |
| WO2006119211A2 (en) * | 2005-05-02 | 2006-11-09 | Genaera Corporation | Methods and compositions for treating ocular disorders |
| US20060283742A1 (en) * | 2005-06-16 | 2006-12-21 | Canel Lightning Co. Ltd. | Multi-lamp display packaging for lamps with collapsible lampshades |
| US20070190180A1 (en) * | 2005-11-08 | 2007-08-16 | Pilkiewicz Frank G | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intravenously |
| US20070190181A1 (en) * | 2005-11-08 | 2007-08-16 | Pilkiewicz Frank G | Methods of treating cancer with lipid-based platinum compound forumulations administered intravenously |
| US20070190182A1 (en) * | 2005-11-08 | 2007-08-16 | Pilkiewicz Frank G | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
| US9107824B2 (en) | 2005-11-08 | 2015-08-18 | Insmed Incorporated | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
| US20070122350A1 (en) * | 2005-11-30 | 2007-05-31 | Transave, Inc. | Safe and effective methods of administering therapeutic agents |
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- 1997-04-25 CA CA002252584A patent/CA2252584C/en not_active Expired - Lifetime
- 1997-04-25 WO PCT/US1997/007011 patent/WO1997040835A1/en not_active Ceased
- 1997-04-25 US US08/840,706 patent/US6147060A/en not_active Expired - Lifetime
- 1997-04-25 AU AU27441/97A patent/AU735884B2/en not_active Ceased
- 1997-04-25 PT PT97921396T patent/PT910382E/pt unknown
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- 1997-04-25 DE DE69722793T patent/DE69722793T2/de not_active Expired - Lifetime
- 1997-04-25 EP EP97921396A patent/EP0910382B1/en not_active Expired - Lifetime
- 1997-04-25 JP JP09539076A patent/JP2000510460A/ja active Pending
- 1997-04-25 AT AT97921396T patent/ATE242635T1/de not_active IP Right Cessation
- 1997-04-25 ES ES97921396T patent/ES2201296T3/es not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008514726A (ja) * | 2004-09-30 | 2008-05-08 | ザ ユニヴァーシティー オヴ シカゴ | ヘッジホッグ阻害剤、放射線及び化学療法薬の併用療法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US6147060A (en) | 2000-11-14 |
| PT910382E (pt) | 2003-10-31 |
| EP0910382A1 (en) | 1999-04-28 |
| DE69722793T2 (de) | 2004-05-19 |
| CA2252584A1 (en) | 1997-11-06 |
| EP0910382B1 (en) | 2003-06-11 |
| AU735884B2 (en) | 2001-07-19 |
| ATE242635T1 (de) | 2003-06-15 |
| ES2201296T3 (es) | 2004-03-16 |
| AU2744197A (en) | 1997-11-19 |
| DK0910382T3 (da) | 2003-10-06 |
| WO1997040835A1 (en) | 1997-11-06 |
| DE69722793D1 (de) | 2003-07-17 |
| CA2252584C (en) | 2008-06-10 |
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