DE69621317D1 - Herstellung einer langsam freisetzenden Zubereitung zur Injektion - Google Patents

Herstellung einer langsam freisetzenden Zubereitung zur Injektion

Info

Publication number
DE69621317D1
DE69621317D1 DE69621317T DE69621317T DE69621317D1 DE 69621317 D1 DE69621317 D1 DE 69621317D1 DE 69621317 T DE69621317 T DE 69621317T DE 69621317 T DE69621317 T DE 69621317T DE 69621317 D1 DE69621317 D1 DE 69621317D1
Authority
DE
Germany
Prior art keywords
microspheres
preparation
injection
temperature
solution containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69621317T
Other languages
English (en)
Other versions
DE69621317T2 (de
Inventor
Okada Hiroaki
Yayoi Douken
Akihiro Yamada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE69621317D1 publication Critical patent/DE69621317D1/de
Publication of DE69621317T2 publication Critical patent/DE69621317T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69621317T 1995-12-15 1996-12-13 Herstellung einer langsam freisetzenden Zubereitung zur Injektion Expired - Lifetime DE69621317T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP32768995 1995-12-15

Publications (2)

Publication Number Publication Date
DE69621317D1 true DE69621317D1 (de) 2002-06-27
DE69621317T2 DE69621317T2 (de) 2002-11-14

Family

ID=18201882

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69621317T Expired - Lifetime DE69621317T2 (de) 1995-12-15 1996-12-13 Herstellung einer langsam freisetzenden Zubereitung zur Injektion

Country Status (5)

Country Link
US (1) US6190700B1 (de)
EP (1) EP0781548B1 (de)
AT (1) ATE217790T1 (de)
CA (1) CA2192773C (de)
DE (1) DE69621317T2 (de)

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EP1389467B1 (de) 2001-05-23 2013-07-03 Mitsubishi Tanabe Pharma Corporation Therapeutische Zusammensetzungen für die regenerative Behandlung von Knorpelerkrankungen
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ES2554106T3 (es) * 2001-06-21 2015-12-16 Genentech, Inc. Formulación de liberación sostenida
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KR101041767B1 (ko) * 2002-06-25 2011-06-17 다케다 야쿠힌 고교 가부시키가이샤 서방성 조성물의 제조 방법
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CA2500661A1 (en) 2002-10-01 2004-04-15 Chiron Corporation Anti-cancer and anti-infectious disease compositions and methods for using same
EP1620140B1 (de) * 2003-05-05 2013-10-09 Ben-Gurion University Of The Negev Research And Development Authority Injizierbare vernetzte polymere zusammensetzungen und deren verwendungen
US20090169520A1 (en) * 2004-01-09 2009-07-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compounds, Pharmaceutical Compositions and Therapeutic Methods of Preventing and Treating Diseases and Disorders Associated With Amyloid Fibril Formation
TW200529890A (en) * 2004-02-10 2005-09-16 Takeda Pharmaceutical Sustained-release preparations
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US20090123556A1 (en) * 2005-03-01 2009-05-14 Sun Pharmaceutical Industries Limited Sustained release pharmaceutical compositions
WO2006123360A2 (en) * 2005-03-01 2006-11-23 Sun Pharmaceutical Industries Limited Microspheres containing octreotide acetate
JPWO2007029361A1 (ja) * 2005-09-02 2009-03-12 武田薬品工業株式会社 短鎖デオキシリボ核酸又は短鎖リボ核酸含有徐放性マイクロスフェア及びその製造法
KR100722607B1 (ko) * 2006-05-11 2007-05-28 주식회사 펩트론 분산성 및 주사 투여능이 향상된 서방성 미립구의 제조방법
WO2008021133A2 (en) 2006-08-09 2008-02-21 Intarcia Therapeutics, Inc. Osmotic delivery systems and piston assemblies
US10669383B2 (en) * 2006-10-31 2020-06-02 Evonik Corporation Spheronized polymer particles
CL2007003658A1 (es) 2006-12-18 2008-05-09 Takeda Pharmaceutical Composicion de liberacion sostenida que comprende un peptido; procedimiento para preparar dicha composicion; agente profilactico o terapeutico para cancer de prostata, hiperplasia prostatica, endometriosis, fibroide uterino, fibroma uterino, pubertad
EP2157967B1 (de) 2007-04-23 2013-01-16 Intarcia Therapeutics, Inc Suspensionsformulierungen insulinotroper peptide und ihre verwendung
EP2240155B1 (de) 2008-02-13 2012-06-06 Intarcia Therapeutics, Inc Vorrichtungen, formulierungen und verfahren zur freisetzung mehrerer wirkstoffe
WO2010009291A1 (en) * 2008-07-16 2010-01-21 Surmodics Pharmaceuticals, Inc. Process for preparing microparticles containing bioactive peptides
AU2009289529B2 (en) 2008-09-04 2015-05-28 Amylin Pharmaceuticals, Llc Sustained release formulations using non-aqueous carriers
CN104323981B (zh) 2009-09-28 2019-03-12 精达制药公司 基本稳态药物递送的快速建立和/或终止
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
WO2013006661A2 (en) 2011-07-06 2013-01-10 President And Fellows Of Harvard College Multiple emulsions and techniques for the formation of multiple emulsions
US9492548B2 (en) * 2012-12-14 2016-11-15 Intervet Inc. Emulsion containing a non-live medicinal substance
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
WO2016196851A2 (en) 2015-06-03 2016-12-08 Intarcia Therapeutics, Inc. Implant placement and removal systems
MX2018014016A (es) 2016-05-16 2019-08-01 Intarcia Therapeutics Inc Polipéptidos selectivos del receptor de glucagón y métodos para utilizarlos.
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
CN110225762A (zh) 2017-01-03 2019-09-10 因塔西亚制药公司 包括glp-1受体激动剂的连续施用和药物的共同施用的方法
CN113440597A (zh) * 2021-07-02 2021-09-28 山东谷雨春生物科技有限公司 一种制备亮丙瑞林微球的方法

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IT1240643B (it) 1990-05-11 1993-12-17 Mediolanum Farmaceutici Spa Peptidi biologicamente attivi contenenti in catena 2-alchiltriptofano
YU48420B (sh) 1991-03-25 1998-07-10 Hoechst Aktiengesellschaft Postupak za dobijanje biološki razgradljivih mikročestica sa dugotrajnim delovanjem
JP3205884B2 (ja) 1991-10-01 2001-09-04 武田薬品工業株式会社 凝集防止剤をコーティングした徐放性微粒子製剤
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JP3277342B2 (ja) 1992-09-02 2002-04-22 武田薬品工業株式会社 徐放性マイクロカプセルの製造法
JP2691667B2 (ja) 1992-09-28 1997-12-17 光技術研究開発株式会社 光半導体素子およびその製造方法
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Also Published As

Publication number Publication date
CA2192773A1 (en) 1997-06-16
EP0781548A3 (de) 1998-07-08
US6190700B1 (en) 2001-02-20
EP0781548A2 (de) 1997-07-02
DE69621317T2 (de) 2002-11-14
CA2192773C (en) 2008-09-23
ATE217790T1 (de) 2002-06-15
EP0781548B1 (de) 2002-05-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: TAKEDA PHARMACEUTICAL CO. LTD., OSAKA, JP