DE69621166D1 - Elektrostatisch bindender makromolekulärer Mizellen-Typ Wirkstoffträger mit daran gebundenem Wirkstoff - Google Patents

Elektrostatisch bindender makromolekulärer Mizellen-Typ Wirkstoffträger mit daran gebundenem Wirkstoff

Info

Publication number
DE69621166D1
DE69621166D1 DE69621166T DE69621166T DE69621166D1 DE 69621166 D1 DE69621166 D1 DE 69621166D1 DE 69621166 T DE69621166 T DE 69621166T DE 69621166 T DE69621166 T DE 69621166T DE 69621166 D1 DE69621166 D1 DE 69621166D1
Authority
DE
Germany
Prior art keywords
drug
attached
electrostatically binding
type
macromolecular micelle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69621166T
Other languages
English (en)
Other versions
DE69621166T2 (de
Inventor
Yasuhisa Sakurai
Teruo Okano
Kazunori Kataoka
Masayuki Yokoyama
Satoshi Katayose
Satoru Suwa
Atsushi Harada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TOUDAI TLO, LTD., TOKYO, JP
Original Assignee
Research Development Corp of Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Development Corp of Japan filed Critical Research Development Corp of Japan
Publication of DE69621166D1 publication Critical patent/DE69621166D1/de
Application granted granted Critical
Publication of DE69621166T2 publication Critical patent/DE69621166T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyesters Or Polycarbonates (AREA)
DE69621166T 1995-01-10 1996-01-10 Elektrostatisch bindender makromolekulärer Mizellen-Typ Wirkstoffträger mit daran gebundenem Wirkstoff Expired - Lifetime DE69621166T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7002210A JP2690276B2 (ja) 1995-01-10 1995-01-10 静電結合型高分子ミセル薬物担体とその薬剤

Publications (2)

Publication Number Publication Date
DE69621166D1 true DE69621166D1 (de) 2002-06-20
DE69621166T2 DE69621166T2 (de) 2002-11-14

Family

ID=11522995

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69621166T Expired - Lifetime DE69621166T2 (de) 1995-01-10 1996-01-10 Elektrostatisch bindender makromolekulärer Mizellen-Typ Wirkstoffträger mit daran gebundenem Wirkstoff

Country Status (8)

Country Link
US (3) US20010000510A1 (de)
EP (1) EP0721776B1 (de)
JP (1) JP2690276B2 (de)
KR (2) KR100664527B1 (de)
AU (1) AU4090096A (de)
CA (1) CA2166931C (de)
DE (1) DE69621166T2 (de)
ES (1) ES2174024T3 (de)

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WO2003084518A2 (fr) 2002-04-09 2003-10-16 Flamel Technologies Suspension orale de microcapsules de principes actifs
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FR2840614B1 (fr) 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
FR2843117B1 (fr) 2002-07-30 2004-10-15 Flamel Tech Sa Polyaminoacides fonctionnalises par au moins un groupement hydrophobe et leurs applications notamment therapeutiques
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AU2009224286B2 (en) * 2008-03-10 2014-06-12 The University Of Tokyo Copolymer including uncharged hydrophilic block and cationic polyamino acid block having hydrophobic group in part of side chains, and use thereof
EP2284210B1 (de) * 2008-04-30 2017-12-06 The University of Tokyo Ladungskonvertierbares ternäres polyplex
EP2331075B1 (de) 2008-08-29 2015-07-29 Genzyme Corporation Peptidformulierungen mit gesteuerter freisetzung
WO2010083154A2 (en) * 2009-01-13 2010-07-22 The Uab Research Foundation Heterofunctional segment-poly(ethylene glycol) polymers as delivery vehicles
WO2010098265A1 (ja) * 2009-02-27 2010-09-02 国立大学法人 東京大学 プロテアソームインヒビター内包高分子ミセル
WO2010106700A1 (ja) * 2009-03-17 2010-09-23 国立大学法人東京大学 タンパク質の電荷調節剤、及びタンパク質内包高分子ミセル複合体
JP5622254B2 (ja) 2009-03-31 2014-11-12 国立大学法人東京大学 二本鎖リボ核酸ポリイオンコンプレックス
WO2010137167A1 (ja) 2009-05-29 2010-12-02 トヨタ自動車株式会社 半導体装置
JP5463531B2 (ja) * 2009-07-22 2014-04-09 国立大学法人 東京大学 Ｐｈｄ２発現抑制物質搭載ポリイオンコンプレックス
SG183374A1 (en) * 2010-02-24 2012-09-27 Arrowhead Res Corp Compositions for targeted delivery of sirna
EP3417934B1 (de) 2010-05-21 2023-12-27 Japan Science And Technology Agency Vesikel mit eingekapselter substanz und verfahren zur herstellung davon
US9314529B2 (en) 2010-07-09 2016-04-19 The University Of Tokyo Nucleic acid delivery composition and carrier composition, pharmaceutical composition using the same, and method for nucleic acid delivery
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US9320814B2 (en) * 2011-11-01 2016-04-26 Board Of Regents Of The University Of Nebraska Polyplexes of hydrophobically-modified siRNA for delivery of siRNA
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CN105188905B (zh) 2013-03-01 2019-01-15 国立研究开发法人科学技术振兴机构 物质包封微囊及其制备方法
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JP5971264B2 (ja) 2014-01-10 2016-08-17 Ｊｆｅスチール株式会社 極厚肉油井管用ねじ継手
JP6106103B2 (ja) 2014-01-16 2017-03-29 信越化学工業株式会社 末端にアミノ基を有する狭分散ポリアルキレングリコール誘導体の製造方法、並びにこれに用いる新規なアセタール基含有アルコール化合物及びそのアルカリ金属塩
JP6106104B2 (ja) 2014-01-16 2017-03-29 信越化学工業株式会社 末端にアミノ基を有する狭分散ポリアルキレングリコール誘導体の製造方法
CN105524271B (zh) * 2014-10-24 2018-07-03 江苏师范大学 胆酸修饰的聚氨基酸嵌段共聚物的合成及应用
CN105524272B (zh) * 2014-10-24 2018-08-21 江苏师范大学 硫辛酸修饰的聚乙二醇-聚氨基酸嵌段共聚物的制备和应用
US10377775B2 (en) 2014-12-04 2019-08-13 Shin-Etsu Chemical Co., Ltd. Method for producing polyalkylene glycol derivative having amino group at end
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JP6463229B2 (ja) 2014-12-04 2019-01-30 信越化学工業株式会社 末端にアミノ基を有するポリアルキレングリコール誘導体の製造方法、並びにこれに用いる重合開始剤及びその原料となるアルコール化合物
KR102094200B1 (ko) * 2017-02-28 2020-03-27 중앙대학교 산학협력단 인돌-3-아세트산을 포함하는 광역학 진단 또는 치료용 조성물
JP6848743B2 (ja) 2017-07-24 2021-03-24 信越化学工業株式会社 ポリアルキレングリコール誘導体の製造方法及び精製方法
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Also Published As

Publication number Publication date
US20010000510A1 (en) 2001-04-26
JP2690276B2 (ja) 1997-12-10
CA2166931C (en) 2008-05-20
US20060025330A1 (en) 2006-02-02
AU4090096A (en) 1996-07-18
DE69621166T2 (de) 2002-11-14
KR960028904A (ko) 1996-08-17
JPH08188541A (ja) 1996-07-23
EP0721776B1 (de) 2002-05-15
ES2174024T3 (es) 2002-11-01
KR100839900B1 (ko) 2008-06-20
KR100664527B1 (ko) 2008-11-12
US20020082198A1 (en) 2002-06-27
CA2166931A1 (en) 1996-07-11
EP0721776A1 (de) 1996-07-17
KR20060106972A (ko) 2006-10-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: JAPAN SCIENCE AND TECHNOLOGY CORP., KAWAGUCHI,, JP

8327 Change in the person/name/address of the patent owner

Owner name: JAPAN SCIENCE AND TECHNOLOGY AGENCY, KAWAGUCHI, JP

8327 Change in the person/name/address of the patent owner

Owner name: KATAOKA, KAZUNORI, KASHIWA, CHIBA, JP

8327 Change in the person/name/address of the patent owner

Owner name: TOUDAI TLO, LTD., TOKYO, JP

8328 Change in the person/name/address of the agent

Representative=s name: KUDLEK & GRUNERT PATENTANWAELTE PARTNERSCHAFT, 803