FR2814951B1 - Suspension colloidale de particules submicroniques de vectorisation de principes actifs hydrophiles (insuline) et leur mode de preparation - Google Patents

Suspension colloidale de particules submicroniques de vectorisation de principes actifs hydrophiles (insuline) et leur mode de preparation

Info

Publication number
FR2814951B1
FR2814951B1 FR0012836A FR0012836A FR2814951B1 FR 2814951 B1 FR2814951 B1 FR 2814951B1 FR 0012836 A FR0012836 A FR 0012836A FR 0012836 A FR0012836 A FR 0012836A FR 2814951 B1 FR2814951 B1 FR 2814951B1
Authority
FR
France
Prior art keywords
vectorization
insulin
principles
preparation
colloidal suspension
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0012836A
Other languages
English (en)
Other versions
FR2814951A1 (fr
Inventor
Nathan Bryson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Flamel Technologies SA
Original Assignee
Flamel Technologies SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0012836A priority Critical patent/FR2814951B1/fr
Application filed by Flamel Technologies SA filed Critical Flamel Technologies SA
Priority to CNA018168930A priority patent/CN1468095A/zh
Priority to BR0114513-4A priority patent/BR0114513A/pt
Priority to JP2002532199A priority patent/JP2004510729A/ja
Priority to PCT/FR2001/003028 priority patent/WO2002028374A1/fr
Priority to AU2001293939A priority patent/AU2001293939A1/en
Priority to CA002424981A priority patent/CA2424981A1/fr
Priority to EP01974417A priority patent/EP1322296A1/fr
Priority to KR10-2003-7004651A priority patent/KR20030048419A/ko
Priority to MXPA03002977A priority patent/MXPA03002977A/es
Priority to US10/398,133 priority patent/US20040048782A1/en
Publication of FR2814951A1 publication Critical patent/FR2814951A1/fr
Application granted granted Critical
Publication of FR2814951B1 publication Critical patent/FR2814951B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
FR0012836A 2000-10-06 2000-10-06 Suspension colloidale de particules submicroniques de vectorisation de principes actifs hydrophiles (insuline) et leur mode de preparation Expired - Fee Related FR2814951B1 (fr)

Priority Applications (11)

Application Number Priority Date Filing Date Title
FR0012836A FR2814951B1 (fr) 2000-10-06 2000-10-06 Suspension colloidale de particules submicroniques de vectorisation de principes actifs hydrophiles (insuline) et leur mode de preparation
KR10-2003-7004651A KR20030048419A (ko) 2000-10-06 2001-10-01 친수성 활성 성분 (인슐린) 을 운반하기 위한서브마이크론 입자의 콜로이드성 현탁액, 및 그것의 제조방법
JP2002532199A JP2004510729A (ja) 2000-10-06 2001-10-01 親水性活性成分（インスリン）を保持するためのサブミクロン粒子のコロイド懸濁液及びそれらの調製方法
PCT/FR2001/003028 WO2002028374A1 (fr) 2000-10-06 2001-10-01 Suspension colloidale de particules submicroniques de vectorisation de principes actifs hydrophiles (insuline) et leur mode de preparation
AU2001293939A AU2001293939A1 (en) 2000-10-06 2001-10-01 Colloidal suspension of submicronic particles for carrying hydrophilic active principles (insulin) and method for preparing same
CA002424981A CA2424981A1 (fr) 2000-10-06 2001-10-01 Suspension colloidale de particules submicroniques de vectorisation de principes actifs hydrophiles (insuline) et leur mode de preparation
CNA018168930A CN1468095A (zh) 2000-10-06 2001-10-01 用于运载亲水活性成分(胰岛素)的超微颗粒的胶体混悬液及其制备方式
BR0114513-4A BR0114513A (pt) 2000-10-06 2001-10-01 Suspensão coloidal, sólida pulverulento, processo de preparação do sólido pulverulento, processo de preparação da suspensão, produtos intermediários do processo e especialidade farmacêutica, nutricional, fitossanitária ou cosmética
MXPA03002977A MXPA03002977A (es) 2000-10-06 2001-10-01 Suspension coloidal de particulas submicronicas de vectorizacion de principios activos hidrofilicos (insulina) y su modo de preparacion.
US10/398,133 US20040048782A1 (en) 2000-10-06 2001-10-01 Colloidal suspension of submicronic particles for carrying hydrophilic active principles (insulin) and method for preparing same
EP01974417A EP1322296A1 (fr) 2000-10-06 2001-10-01 Suspension colloidale de particules submicroniques de vectorisation de principes actifs hydrophiles (insuline) et leur mode de preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0012836A FR2814951B1 (fr) 2000-10-06 2000-10-06 Suspension colloidale de particules submicroniques de vectorisation de principes actifs hydrophiles (insuline) et leur mode de preparation

Publications (2)

Publication Number Publication Date
FR2814951A1 FR2814951A1 (fr) 2002-04-12
FR2814951B1 true FR2814951B1 (fr) 2003-01-17

Family

ID=8855104

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0012836A Expired - Fee Related FR2814951B1 (fr) 2000-10-06 2000-10-06 Suspension colloidale de particules submicroniques de vectorisation de principes actifs hydrophiles (insuline) et leur mode de preparation

Country Status (11)

Country Link
US (1) US20040048782A1 (fr)
EP (1) EP1322296A1 (fr)
JP (1) JP2004510729A (fr)
KR (1) KR20030048419A (fr)
CN (1) CN1468095A (fr)
AU (1) AU2001293939A1 (fr)
BR (1) BR0114513A (fr)
CA (1) CA2424981A1 (fr)
FR (1) FR2814951B1 (fr)
MX (1) MXPA03002977A (fr)
WO (1) WO2002028374A1 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060015472A (ko) * 2003-03-04 2006-02-17 더 테크놀로지 디벨로프먼트 컴퍼니 리미티드 약물전달 시스템 및 세포 치료법
FR2862541B1 (fr) * 2003-11-21 2007-04-20 Flamel Tech Sa Formulations pharmaceutiques pour la liberation prolongee d'interferons et leurs applications therapeutiques
FR2862535B1 (fr) * 2003-11-21 2007-11-23 Flamel Tech Sa Formulations pharmaceutiques pour la liberation prolongee d'interleukines et leurs applications therapeutiques
JP4929567B2 (ja) * 2004-08-05 2012-05-09 コニカミノルタエムジー株式会社 ポリマーミセル含有製剤の製造方法
NZ556290A (en) * 2005-01-04 2010-11-26 Intezyne Technologies Inc Synthesis of hybrid block copolymers and uses thereof
EP1848460A4 (fr) * 2005-02-11 2008-03-12 Intezyne Technologies Inc Synthese d'homopolymeres et de copolymeres sequences
EP1907444B1 (fr) 2005-04-01 2009-08-19 Intezyne Technologies Incorporated Micelles de polymere servant a la delivrance de medicaments
JP2006321763A (ja) * 2005-05-20 2006-11-30 Hosokawa Funtai Gijutsu Kenkyusho:Kk 生体適合性ナノ粒子及びその製造方法
FR2904219B1 (fr) * 2006-07-28 2010-08-13 Flamel Tech Sa Microparticules a base de copolymere amphiphile et de principe(s) actif(s) a liberation modifiee et formulations pharmaceutiques en contenant
WO2008026776A1 (fr) * 2006-08-31 2008-03-06 Nanocarrier Co., Ltd. Composition transdermique, composition pharmaceutique transdermique et composition cosmétique transdermique comprenant un ingrédient actif encapsulant une micelle polymère
KR20080095130A (ko) * 2007-04-23 2008-10-28 한국과학기술연구원 ｐＨ 민감성 블록공중합체를 이용한 약물전달체 제조 및응용
JP4653242B1 (ja) 2010-02-12 2011-03-16 ナノキャリア株式会社 粒子状医薬組成物
EA027744B1 (ru) * 2011-10-31 2017-08-31 Ксерис Фармасьютикалс, Инк. Лекарственные формы для лечения сахарного диабета
US9957345B2 (en) 2014-08-18 2018-05-01 International Business Machines Corporation 3D printing with PHT based materials
US10023735B2 (en) 2014-08-18 2018-07-17 International Business Machines Corporation 3D printing with PHT/PHA based materials and polymerizable monomers
US9758620B2 (en) 2015-09-03 2017-09-12 International Business Machines Corporation Tailorable viscoelastic properties of PEG-hemiaminal organogel networks
US9873766B2 (en) 2015-11-24 2018-01-23 International Business Machines Corporation Systems chemistry approach to polyhexahydrotriazine polymeric structures
CN110483785B (zh) * 2019-07-01 2020-05-19 中山大学 一种三嵌段聚合物、载药纳米胶束、纳米药物及其制备方法和应用
CN113264997B (zh) * 2021-04-13 2023-07-04 康汉医药(广州)有限公司 一种蛋白药物在常温、高温条件下保存的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4450150A (en) * 1973-05-17 1984-05-22 Arthur D. Little, Inc. Biodegradable, implantable drug delivery depots, and method for preparing and using the same
US4351337A (en) * 1973-05-17 1982-09-28 Arthur D. Little, Inc. Biodegradable, implantable drug delivery device, and process for preparing and using the same
US5286495A (en) * 1992-05-11 1994-02-15 University Of Florida Process for microencapsulating cells
KR940003548U (ko) * 1992-08-14 1994-02-21 김형술 세탁물 건조기
JP2690276B2 (ja) * 1995-01-10 1997-12-10 科学技術振興事業団 静電結合型高分子ミセル薬物担体とその薬剤
FR2732218B1 (fr) * 1995-03-28 1997-08-01 Flamel Tech Sa Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s) et leurs procedes de preparation
FR2746035B1 (fr) * 1996-03-15 1998-06-12 Microparticules de gel composite susceptibles d'etre utilisees comme vecteur(s) de principe(s) actif(s), l'un de leurs procedes de preparation et leurs applications
US6309633B1 (en) * 1999-06-19 2001-10-30 Nobex Corporation Amphiphilic drug-oligomer conjugates with hydroyzable lipophile components and methods for making and using the same

Also Published As

Publication number Publication date
FR2814951A1 (fr) 2002-04-12
WO2002028374A1 (fr) 2002-04-11
US20040048782A1 (en) 2004-03-11
CA2424981A1 (fr) 2002-04-11
KR20030048419A (ko) 2003-06-19
BR0114513A (pt) 2003-10-21
AU2001293939A1 (en) 2002-04-15
EP1322296A1 (fr) 2003-07-02
JP2004510729A (ja) 2004-04-08
MXPA03002977A (es) 2004-12-06
CN1468095A (zh) 2004-01-14

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