DE69615052D1 - Verfahren zur herstellung einer benzimidazolverbindung - Google Patents
Verfahren zur herstellung einer benzimidazolverbindungInfo
- Publication number
- DE69615052D1 DE69615052D1 DE69615052T DE69615052T DE69615052D1 DE 69615052 D1 DE69615052 D1 DE 69615052D1 DE 69615052 T DE69615052 T DE 69615052T DE 69615052 T DE69615052 T DE 69615052T DE 69615052 D1 DE69615052 D1 DE 69615052D1
- Authority
- DE
- Germany
- Prior art keywords
- producing
- benzimidazole compound
- benzimidazole
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9504503A SE521100C2 (sv) | 1995-12-15 | 1995-12-15 | Förfarande för framställning av en bensimidazolförening |
PCT/SE1996/001603 WO1997022603A1 (en) | 1995-12-15 | 1996-12-05 | Method for the synthesis of a benzimidazole compound |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69615052D1 true DE69615052D1 (de) | 2001-10-11 |
DE69615052T2 DE69615052T2 (de) | 2002-06-27 |
Family
ID=20400614
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE0868423T Pending DE868423T1 (de) | 1995-12-15 | 1996-12-05 | Verfahren zur herstellung einer benzimidazolverbindung |
DE69615052T Expired - Fee Related DE69615052T2 (de) | 1995-12-15 | 1996-12-05 | Verfahren zur herstellung einer benzimidazolverbindung |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE0868423T Pending DE868423T1 (de) | 1995-12-15 | 1996-12-05 | Verfahren zur herstellung einer benzimidazolverbindung |
Country Status (40)
Country | Link |
---|---|
US (1) | US5958955A (de) |
EP (1) | EP0868423B1 (de) |
JP (1) | JP3523267B2 (de) |
KR (1) | KR100433436B1 (de) |
CN (1) | CN1113879C (de) |
AR (1) | AR004834A1 (de) |
AT (1) | ATE205201T1 (de) |
AU (1) | AU704422B2 (de) |
CA (1) | CA2238864C (de) |
CO (1) | CO4750654A1 (de) |
CZ (1) | CZ288661B6 (de) |
DE (2) | DE868423T1 (de) |
DK (1) | DK0868423T3 (de) |
DZ (1) | DZ2137A1 (de) |
EE (1) | EE03768B1 (de) |
EG (1) | EG23859A (de) |
ES (1) | ES2125210T3 (de) |
HK (1) | HK1010539A1 (de) |
HR (1) | HRP960581B1 (de) |
HU (1) | HUP9900110A3 (de) |
IL (1) | IL124856A (de) |
IS (1) | IS1891B (de) |
MA (1) | MA24026A1 (de) |
MX (1) | MX9804603A (de) |
MY (1) | MY115661A (de) |
NO (1) | NO314306B1 (de) |
NZ (1) | NZ324482A (de) |
PL (1) | PL186132B1 (de) |
PT (1) | PT868423E (de) |
RU (1) | RU2166502C2 (de) |
SE (1) | SE521100C2 (de) |
SI (1) | SI0868423T1 (de) |
SK (1) | SK282347B6 (de) |
TN (1) | TNSN96148A1 (de) |
TR (1) | TR199801070T2 (de) |
TW (1) | TW460474B (de) |
UA (1) | UA62921C2 (de) |
WO (1) | WO1997022603A1 (de) |
YU (1) | YU49420B (de) |
ZA (1) | ZA9610067B (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE521100C2 (sv) * | 1995-12-15 | 2003-09-30 | Astra Ab | Förfarande för framställning av en bensimidazolförening |
US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US6699885B2 (en) | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
US6645988B2 (en) | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
SK283805B6 (sk) | 1996-09-09 | 2004-02-03 | Slovakofarma, A. S. | Spôsob prípravy omeprazolu |
US6303787B1 (en) * | 1998-05-27 | 2001-10-16 | Natco Pharma Limited | Intermediates and an improved process for the preparation of Omeprazole employing the said intermediates |
SI20019A (sl) * | 1998-07-13 | 2000-02-29 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola |
US6166213A (en) * | 1998-08-11 | 2000-12-26 | Merck & Co., Inc. | Omeprazole process and compositions thereof |
UA72748C2 (en) * | 1998-11-10 | 2005-04-15 | Astrazeneca Ab | A novel crystalline form of omeprazole |
IL142703A (en) | 1998-11-10 | 2006-04-10 | Astrazeneca Ab | Crystalline form of omeprazole |
DE19951960C2 (de) * | 1999-10-28 | 2002-06-27 | Gruenenthal Gmbh | Verfahren zur Herstellung als Ulkustherapeutika geeigneter Benzimidazol-Derivate |
MXPA04007169A (es) * | 2002-01-25 | 2004-10-29 | Santarus Inc | Suministro transmucosal de inhibidores de bomba de protones. |
SE0203092D0 (en) * | 2002-10-18 | 2002-10-18 | Astrazeneca Ab | Method for the synthesis of a benzimidazole compound |
US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8815916B2 (en) | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
TR200705749T1 (tr) | 2004-12-16 | 2007-12-24 | Cipla Ltd. | İşlem. |
CN100393712C (zh) * | 2006-01-23 | 2008-06-11 | 中国科学院成都有机化学有限公司 | 苯并咪唑型质子泵抑止剂及其前体的改进制备和分离纯化方法 |
WO2007122686A1 (ja) * | 2006-04-14 | 2007-11-01 | Eisai R & D Management Co., Ltd. | ベンズイミダゾール化合物 |
CA2678702A1 (en) * | 2007-02-21 | 2008-08-28 | Cipla Limited | Process for the preparation of esomeprazole magnesium dihydrate |
CN101492459B (zh) * | 2008-01-25 | 2011-04-27 | 山东轩竹医药科技有限公司 | 含烷氧乙酰基二氢异噁唑并吡啶化合物 |
CN101497603B (zh) * | 2008-01-30 | 2012-11-07 | 山东轩竹医药科技有限公司 | 含有被烷氧烷胺氧基取代的吡啶的苯并咪唑衍生物 |
CN103664885A (zh) * | 2013-12-12 | 2014-03-26 | 武汉工程大学 | 苯并咪唑型质子泵抑制剂中间体的制备方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US461997A (en) * | 1891-10-27 | Sand-pump or other pipes | ||
SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
JPS6150978A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
US4619997A (en) * | 1984-09-06 | 1986-10-28 | The Upjohn Company | Substituted 2-pyridylmethylthio and sulfinyl-benzimidazoles as gastric antisecretory agents |
IL76839A (en) * | 1984-10-31 | 1988-08-31 | Byk Gulden Lomberg Chem Fab | Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
SE9002043D0 (sv) * | 1990-06-07 | 1990-06-07 | Astra Ab | Improved method for synthesis |
WO1993006097A1 (en) * | 1991-09-20 | 1993-04-01 | Merck & Co., Inc. | Novel process for the preparation of anti-ulcer agents |
SE521100C2 (sv) * | 1995-12-15 | 2003-09-30 | Astra Ab | Förfarande för framställning av en bensimidazolförening |
-
1995
- 1995-12-15 SE SE9504503A patent/SE521100C2/sv not_active IP Right Cessation
-
1996
- 1996-05-12 UA UA98052782A patent/UA62921C2/uk unknown
- 1996-11-29 ZA ZA9610067A patent/ZA9610067B/xx unknown
- 1996-12-02 AR ARP960105459A patent/AR004834A1/es active IP Right Grant
- 1996-12-02 TN TNTNSN96148A patent/TNSN96148A1/fr unknown
- 1996-12-03 TW TW085114881A patent/TW460474B/zh not_active IP Right Cessation
- 1996-12-04 DZ DZ960182A patent/DZ2137A1/fr active
- 1996-12-04 YU YU64296A patent/YU49420B/sh unknown
- 1996-12-04 MA MA24415A patent/MA24026A1/fr unknown
- 1996-12-05 US US08/776,222 patent/US5958955A/en not_active Expired - Lifetime
- 1996-12-05 KR KR10-1998-0704454A patent/KR100433436B1/ko not_active IP Right Cessation
- 1996-12-05 WO PCT/SE1996/001603 patent/WO1997022603A1/en active IP Right Grant
- 1996-12-05 EE EE9800183A patent/EE03768B1/xx not_active IP Right Cessation
- 1996-12-05 CA CA002238864A patent/CA2238864C/en not_active Expired - Fee Related
- 1996-12-05 AT AT96942702T patent/ATE205201T1/de not_active IP Right Cessation
- 1996-12-05 AU AU11550/97A patent/AU704422B2/en not_active Ceased
- 1996-12-05 JP JP52269797A patent/JP3523267B2/ja not_active Expired - Fee Related
- 1996-12-05 DK DK96942702T patent/DK0868423T3/da active
- 1996-12-05 EP EP96942702A patent/EP0868423B1/de not_active Expired - Lifetime
- 1996-12-05 DE DE0868423T patent/DE868423T1/de active Pending
- 1996-12-05 CZ CZ19981685A patent/CZ288661B6/cs not_active IP Right Cessation
- 1996-12-05 SI SI9630367T patent/SI0868423T1/xx unknown
- 1996-12-05 HU HU9900110A patent/HUP9900110A3/hu unknown
- 1996-12-05 PL PL96327334A patent/PL186132B1/pl not_active IP Right Cessation
- 1996-12-05 CN CN96199057A patent/CN1113879C/zh not_active Expired - Fee Related
- 1996-12-05 ES ES96942702T patent/ES2125210T3/es not_active Expired - Lifetime
- 1996-12-05 IL IL12485696A patent/IL124856A/en not_active IP Right Cessation
- 1996-12-05 NZ NZ324482A patent/NZ324482A/xx unknown
- 1996-12-05 TR TR1998/01070T patent/TR199801070T2/xx unknown
- 1996-12-05 SK SK768-98A patent/SK282347B6/sk not_active IP Right Cessation
- 1996-12-05 DE DE69615052T patent/DE69615052T2/de not_active Expired - Fee Related
- 1996-12-05 PT PT96942702T patent/PT868423E/pt unknown
- 1996-12-05 RU RU98110659/04A patent/RU2166502C2/ru not_active IP Right Cessation
- 1996-12-09 HR HR960581A patent/HRP960581B1/xx not_active IP Right Cessation
- 1996-12-11 CO CO96065025A patent/CO4750654A1/es unknown
- 1996-12-13 MY MYPI96005252A patent/MY115661A/en unknown
- 1996-12-14 EG EG112296A patent/EG23859A/xx active
-
1998
- 1998-05-22 IS IS4750A patent/IS1891B/is unknown
- 1998-06-08 NO NO19982624A patent/NO314306B1/no not_active IP Right Cessation
- 1998-06-09 MX MX9804603A patent/MX9804603A/es not_active IP Right Cessation
- 1998-10-29 HK HK98111601A patent/HK1010539A1/xx not_active IP Right Cessation
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de | ||
8370 | Indication related to discontinuation of the patent is to be deleted | ||
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |