DE60332026D1 - Ubstituierter alpha-ketosäure - Google Patents

Ubstituierter alpha-ketosäure

Info

Publication number
DE60332026D1
DE60332026D1 DE60332026T DE60332026T DE60332026D1 DE 60332026 D1 DE60332026 D1 DE 60332026D1 DE 60332026 T DE60332026 T DE 60332026T DE 60332026 T DE60332026 T DE 60332026T DE 60332026 D1 DE60332026 D1 DE 60332026D1
Authority
DE
Germany
Prior art keywords
ubstituated
alpha
acid
ketoic acid
ketoic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60332026T
Other languages
English (en)
Inventor
Masakazu Sugiyama
Kunihiko Watanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Application granted granted Critical
Publication of DE60332026D1 publication Critical patent/DE60332026D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/50—Polycarboxylic acids having keto groups, e.g. 2-ketoglutaric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Lubricants (AREA)
DE60332026T 2002-08-26 2003-08-26 Ubstituierter alpha-ketosäure Expired - Lifetime DE60332026D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2002245980 2002-08-26
JP2003171299 2003-06-16
PCT/JP2003/010750 WO2004018672A1 (ja) 2002-08-26 2003-08-26 新規アルドラーゼおよび置換α−ケト酸の製造方法

Publications (1)

Publication Number Publication Date
DE60332026D1 true DE60332026D1 (de) 2010-05-20

Family

ID=31949581

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60332026T Expired - Lifetime DE60332026D1 (de) 2002-08-26 2003-08-26 Ubstituierter alpha-ketosäure

Country Status (12)

Country Link
US (6) US7351569B2 (de)
EP (3) EP2210943A1 (de)
JP (2) JP4670347B2 (de)
KR (1) KR100741650B1 (de)
CN (2) CN103525847A (de)
AT (1) ATE463568T1 (de)
AU (1) AU2003261722A1 (de)
CA (2) CA2714881C (de)
DE (1) DE60332026D1 (de)
DK (1) DK1533376T3 (de)
RU (1) RU2307871C2 (de)
WO (1) WO2004018672A1 (de)

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ATE552242T1 (de) * 2001-12-27 2012-04-15 Ajinomoto Kk ßVERFAHREN ZUR HERSTELLUNG VON GLUTAMINSÄUREVERBINDUNGEN UND ZWISCHENPRODUKTEN DAVON, UND IN DEN VERFAHREN VERWENDETE NEUE ZWISCHENPRODUKTEß
ATE497013T1 (de) * 2001-12-27 2011-02-15 Ajinomoto Kk Verfahren zur herstellung von glutaminsäurederivaten
US7572607B2 (en) 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
US8372989B2 (en) 2002-04-23 2013-02-12 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
CN103525847A (zh) 2002-08-26 2014-01-22 味之素株式会社 新型醛缩酶和取代α-酮酸的制备方法
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AU2004286207B2 (en) 2003-10-21 2011-02-24 Cargill, Incorporated Production of monatin and monatin precursors
JP4604524B2 (ja) * 2004-03-16 2011-01-05 味の素株式会社 変異型アルドラーゼ、並びにこれを用いた光学活性ｉｈｏｇ及び光学活性モナティンの製造方法
US7935377B2 (en) * 2004-06-04 2011-05-03 Ajinomoto Co., Inc. Crystals of free (2R, 4R)-monatin and use thereof
CA2506247C (en) 2004-06-07 2012-02-21 Ajinomoto Co., Inc. Novel aldolase, and method for producing optically active ihog and monatin
JP4797452B2 (ja) * 2004-06-07 2011-10-19 味の素株式会社 新規アルドラーゼ並びに光学活性ｉｈｏｇ及びモナティンの製造方法
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WO2006113897A2 (en) 2005-04-20 2006-10-26 Cargill, Incorporated Products and methods for in vivo secretion of monatin
US7582455B2 (en) 2005-04-26 2009-09-01 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
US8076108B2 (en) 2005-04-26 2011-12-13 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
EP3153580A3 (de) 2006-03-07 2017-04-19 BASF Enzymes LLC Aldolasen, nukleinsäuren zur codierung davon sowie verfahren zur herstellung und verwendung davon
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CN101239941B (zh) 2007-02-08 2012-02-29 味之素株式会社 光学活性化合物的制造方法
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US9523105B2 (en) * 2010-08-30 2016-12-20 Arzeda Corporation Fermentation route for the production of levulinic acid, levulinate esters and valerolactone and derivatives thereof
EP3630798B1 (de) * 2017-05-27 2022-11-23 Enzymaster (Ningbo) Bio-Engineering Co., Ltd. Veränderte aldolase polypeptide und deren anwendung in der synthese von beta-hydroxy-alpha-aminosäuren
CN107306532B (zh) * 2017-06-13 2021-09-07 南京农业大学 一种利用复合PAHs降解菌同时去除植物体内USEPA PAHs的方法

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US20120040416A1 (en) 2012-02-16
CA2484871A1 (en) 2004-03-04
EP2210943A1 (de) 2010-07-28
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JPWO2004018672A1 (ja) 2005-12-08
US7351569B2 (en) 2008-04-01
JP4670347B2 (ja) 2011-04-13
JP2010284170A (ja) 2010-12-24
US20080318290A1 (en) 2008-12-25
US20130157342A1 (en) 2013-06-20
CA2714881A1 (en) 2004-03-04
EP2280068A1 (de) 2011-02-02
RU2307871C2 (ru) 2007-10-10
US8273556B2 (en) 2012-09-25
RU2005108605A (ru) 2005-10-27
ATE463568T1 (de) 2010-04-15
AU2003261722A1 (en) 2004-03-11
KR20050058516A (ko) 2005-06-16
EP1533376A1 (de) 2005-05-25
EP1533376A4 (de) 2006-09-06
CN103525847A (zh) 2014-01-22
US20050153405A1 (en) 2005-07-14
WO2004018672A1 (ja) 2004-03-04
KR100741650B1 (ko) 2007-07-24
CN1678742B (zh) 2013-07-17
US20130252310A1 (en) 2013-09-26
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US8058038B2 (en) 2011-11-15
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CN1678742A (zh) 2005-10-05
US8697416B2 (en) 2014-04-15

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