NO20074642L - Fremgangsmate for a lage trans-1-((1R,3S)-6-klor-3-fenylindan-1-yl)-3,3-dimetylpiperazin - Google Patents
Fremgangsmate for a lage trans-1-((1R,3S)-6-klor-3-fenylindan-1-yl)-3,3-dimetylpiperazinInfo
- Publication number
- NO20074642L NO20074642L NO20074642A NO20074642A NO20074642L NO 20074642 L NO20074642 L NO 20074642L NO 20074642 A NO20074642 A NO 20074642A NO 20074642 A NO20074642 A NO 20074642A NO 20074642 L NO20074642 L NO 20074642L
- Authority
- NO
- Norway
- Prior art keywords
- phenylindan
- chloro
- dimethylpiperazine
- formula
- preparing trans
- Prior art date
Links
- 239000012971 dimethylpiperazine Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- BYPMJBXPNZMNQD-PZJWPPBQSA-N Zicronapine Chemical compound C1C(C)(C)N(C)CCN1[C@H]1C2=CC(Cl)=CC=C2[C@H](C=2C=CC=CC=2)C1 BYPMJBXPNZMNQD-PZJWPPBQSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C25/00—Compounds containing at least one halogen atom bound to a six-membered aromatic ring
- C07C25/18—Polycyclic aromatic halogenated hydrocarbons
- C07C25/22—Polycyclic aromatic halogenated hydrocarbons with condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
- C07C45/292—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
- C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Beskrevet er en fremgangsmåte for å lage trans-1-((1R,3S)-6-klor-3-fenylindan-1-yl)-3,3-dimetylpiperazin (formel I) og salter derav og en lignende fremgangsmåte for å lage 4-((1R,3S)-6-klor-3-fenylindan-1-yl)-1,2,2-trimetylpiperazin (formel IX) og salter derav, hvilken fremgangsmåte omfatter omdannelse av en forbindelse med formel IVa til henholdsvis forbindelsen med formel I eller forbindelsen med formel IX.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65342805P | 2005-02-16 | 2005-02-16 | |
DKPA200500237 | 2005-02-16 | ||
PCT/DK2006/000086 WO2006086984A1 (en) | 2005-02-16 | 2006-02-14 | Process for making trans-1-((1r, 3s)-6-chloro-3-phenylindan-1-yl)-3, 3-dimethylpiperazine |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20074642L true NO20074642L (no) | 2007-09-12 |
Family
ID=38323790
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20074642A NO20074642L (no) | 2005-02-16 | 2007-09-12 | Fremgangsmate for a lage trans-1-((1R,3S)-6-klor-3-fenylindan-1-yl)-3,3-dimetylpiperazin |
Country Status (20)
Country | Link |
---|---|
US (2) | US8569499B2 (no) |
EP (1) | EP1853574A1 (no) |
JP (1) | JP5148289B2 (no) |
KR (1) | KR101364365B1 (no) |
CN (1) | CN101137632B (no) |
AR (1) | AR054735A1 (no) |
AU (1) | AU2006215955B2 (no) |
BR (1) | BRPI0607438A2 (no) |
CA (1) | CA2597615C (no) |
EA (1) | EA018059B1 (no) |
HK (1) | HK1123544A1 (no) |
IL (1) | IL184553A (no) |
MX (1) | MX2007009814A (no) |
MY (1) | MY148242A (no) |
NO (1) | NO20074642L (no) |
NZ (1) | NZ556517A (no) |
TW (1) | TWI453198B (no) |
UA (1) | UA106191C2 (no) |
WO (1) | WO2006086984A1 (no) |
ZA (1) | ZA200705984B (no) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5043429B2 (ja) | 2003-08-18 | 2012-10-10 | ハー・ルンドベック・アクチエゼルスカベット | トランス−4−((1r,3s)−6−クロロ−3−フェニルインダン−1−イル)−1,2,2−トリメチルピペラジンのコハク酸塩およびマロン酸塩、および薬剤としての使用方法 |
TWI376373B (en) | 2005-02-16 | 2012-11-11 | Lundbeck & Co As H | Crystalline base of a pharmaceutical compound |
TWI453198B (zh) * | 2005-02-16 | 2014-09-21 | Lundbeck & Co As H | 製造反式-1-((1r,3s)-6-氯基-3-苯基茚滿-1-基) -3 , 3 -二甲基六氫吡與其鹽類之方法及製造4-((1r , 3s)-6 -氯基-3-苯基茚滿-1-基 )-1,2,2-三甲基六氫吡與其鹽類之方法 |
TW200819426A (en) | 2006-08-31 | 2008-05-01 | Lundbeck & Co As H | Novel indane compounds |
TW201102370A (en) | 2009-07-07 | 2011-01-16 | Lundbeck & Co As H | Manufacture of 4-((1R,3S)-6-chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine and 1-((1R,3S)-6-chloro-3-phenyl-indan-1-yl)-3,3-dimethyl piperazine |
JP5941410B2 (ja) * | 2010-11-09 | 2016-06-29 | 株式会社カネカ | ハロゲン化インデノン類及びそれを用いた光学活性インダノン類又は光学活性インダノール類の製造方法 |
JP2014501771A (ja) * | 2011-01-07 | 2014-01-23 | ハー・ルンドベック・アクチエゼルスカベット | 4−((1r,3s)−6−クロロ−3−フェニル−インダン−1−イル)−1,2,2−トリメチル−ピペラジンと1−((1r,3s)−6−クロロ−3−フェニル−インダン,1−イル)−3,3−ジメチル−ピペラジンとを分割するための方法 |
ME03375B (me) | 2011-06-20 | 2020-01-20 | H Lundbeck As | Deuterizovani 1-piperazin0-3-fenil indani za tretiranje šizofrenije |
JP5838628B2 (ja) * | 2011-07-25 | 2016-01-06 | 東ソー株式会社 | N−アルキルピペラジン類の製造方法 |
AR094054A1 (es) | 2012-12-19 | 2015-07-08 | H Lundbeck As | 6-cloro-3-(fenil-d₅)-inden-1-ona y uso de la misma |
US20180155311A1 (en) * | 2015-05-26 | 2018-06-07 | Dsm Ip Assets B.V. | Separation of chiral isomers by sfc |
WO2020089147A1 (en) | 2018-10-29 | 2020-05-07 | H. Lundbeck A/S | Amorphous compounds of formula (i) and amorphous compounds of formula (i) salts |
JP2022509965A (ja) | 2018-12-03 | 2022-01-25 | ハー・ルンドベック・アクチエゼルスカベット | 4-((1R,3S)-6-クロロ-3-フェニル-2,3-ジヒドロ-1H-インデン-1-イル)-1,2,2-トリメチルピペラジン及び4-((1R,3S)-6-クロロ-3-(フェニル-d5)-2,3-ジヒドロ-1H-インデン-1-イル)-2,2-ジメチル-1-(メチル-d3)ピペラジンのプロドラッグ |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4031216A (en) | 1974-08-12 | 1977-06-21 | Knoll A.G. Chemische Fabriken | 3-(3,4-Dialkoxy-benzyl)-3-methyl-piperazines |
IE50867B1 (en) | 1980-02-29 | 1986-08-06 | Kefalas As | Indane derivatives |
DE3139970A1 (de) | 1981-10-08 | 1983-04-28 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue carbonsaeurederivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
US5026853A (en) | 1987-04-01 | 1991-06-25 | Janssen Pharmaceutica N.V. | 4-substituted-2(or 3)aminocarbonyl-1-piperazineacetamide |
US5466806A (en) | 1989-02-08 | 1995-11-14 | Biochem Pharma Inc. | Processes for preparing substituted 1,3-oxathiolanes with antiviral properties |
US5643784A (en) * | 1990-12-04 | 1997-07-01 | H, Lundbeck A/S | Indan derivatives |
WO1993008799A1 (en) | 1991-11-05 | 1993-05-13 | Smithkline Beecham Corporation | Endothelin receptor antagonists |
CA2091204C (en) | 1992-03-11 | 1997-04-08 | Ronald J. Mattson | Antiischemic-piperazinyl and piperidinyl-cyclohexanes |
DK55192D0 (da) * | 1992-04-28 | 1992-04-28 | Lundbeck & Co As H | 1-piperazino-1,2-dihydroindenderivater |
JPH06184132A (ja) | 1992-12-22 | 1994-07-05 | Kotobuki Seiyaku Kk | ベンゾフラン誘導体及びその製造方法並びに尿酸排泄剤 |
JP2686366B2 (ja) | 1993-11-30 | 1997-12-08 | ファイザー・インコーポレーテッド | キラルテトラロンの製造方法 |
CA2132411A1 (en) | 1994-09-19 | 1996-03-20 | Michael Trani | Enzymatic esterification of long-chain racemic acids and alcohols |
US6455736B1 (en) | 1994-12-16 | 2002-09-24 | Uop Llc | Process for preparation of pharmaceutically desired sertraline and sertraline analogs |
US6410794B1 (en) | 1994-12-16 | 2002-06-25 | Uop Llc | Process for preparation of pharmaceutically desired chiral tetralone from tetralones |
US5807897A (en) | 1996-03-01 | 1998-09-15 | Zeneca Limited | Aminotetralin derivative and compositions and method of use thereof |
US6268367B1 (en) | 1998-02-23 | 2001-07-31 | Zymogenetics, Inc. | Piperazine derivatives for treating bone deficit conditions |
DE69913332T2 (de) | 1998-05-01 | 2004-05-27 | Pfizer Products Inc., Groton | Verfahren zur herstellung von enantiomeren reinem oder optisch angereicherter sertraline-tetralon durch kontinuierliche chromatographie |
WO1999061426A1 (en) | 1998-05-22 | 1999-12-02 | Scios Inc. | Heterocyclic compounds and methods to treat cardiac failure and other disorders |
DE19824470A1 (de) | 1998-05-30 | 1999-12-02 | Boehringer Ingelheim Pharma | Neue Neurokininantagonisten, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
GB9818916D0 (en) | 1998-08-28 | 1998-10-21 | Smithkline Beecham Plc | Use |
FR2786769B1 (fr) | 1998-12-04 | 2002-10-25 | Synthelabo | Derives de 2,5-diazabicyclo[2.2.1]heptane, leur preparation et leur application en therapeutique |
EP1059302A1 (en) | 1999-06-08 | 2000-12-13 | Aventis Pharma Deutschland GmbH | Factor VIIa inhibitors |
JP2000351773A (ja) | 1999-06-08 | 2000-12-19 | Yamanouchi Pharmaceut Co Ltd | フラン誘導体からなる医薬 |
AR031520A1 (es) | 1999-06-11 | 2003-09-24 | Vertex Pharma | Un compuesto inhibidor de aspartilo proteasa, una composicion que lo comprende y un metodo para tratar un paciente con dicha composicion |
US6369226B1 (en) | 1999-06-21 | 2002-04-09 | Agouron Pharmaceuticals, Inc. | Substituted benzamide inhibitors of rhinovirus 3C protease |
IN187170B (no) | 2000-01-04 | 2002-02-23 | Sun Pharmaceutical Ind Ltd | |
JP2001325541A (ja) | 2000-05-12 | 2001-11-22 | Nec Telecom Syst Ltd | 電子商取引決済システム及び電子商取引決済方法 |
EA200600443A1 (ru) * | 2003-08-18 | 2006-08-25 | Х. Лундбекк А/С | Транс-1-(6-хлор-3-фенилиндан-1-ил)-3,3-диметилпиперазин |
JP5043429B2 (ja) | 2003-08-18 | 2012-10-10 | ハー・ルンドベック・アクチエゼルスカベット | トランス−4−((1r,3s)−6−クロロ−3−フェニルインダン−1−イル)−1,2,2−トリメチルピペラジンのコハク酸塩およびマロン酸塩、および薬剤としての使用方法 |
JP2008530039A (ja) | 2005-02-16 | 2008-08-07 | ハー・ルンドベック・アクチエゼルスカベット | トランス−1−((1r,3s)−6−クロロ−3−フェニルインダン−1−イル)−3,3−ジメチルピペラジンの酒石酸塩およびリンゴ酸塩 |
TWI453198B (zh) * | 2005-02-16 | 2014-09-21 | Lundbeck & Co As H | 製造反式-1-((1r,3s)-6-氯基-3-苯基茚滿-1-基) -3 , 3 -二甲基六氫吡與其鹽類之方法及製造4-((1r , 3s)-6 -氯基-3-苯基茚滿-1-基 )-1,2,2-三甲基六氫吡與其鹽類之方法 |
TWI376373B (en) | 2005-02-16 | 2012-11-11 | Lundbeck & Co As H | Crystalline base of a pharmaceutical compound |
-
2006
- 2006-02-07 TW TW095103996A patent/TWI453198B/zh not_active IP Right Cessation
- 2006-02-14 MX MX2007009814A patent/MX2007009814A/es active IP Right Grant
- 2006-02-14 KR KR1020077016237A patent/KR101364365B1/ko not_active IP Right Cessation
- 2006-02-14 NZ NZ556517A patent/NZ556517A/en not_active IP Right Cessation
- 2006-02-14 EA EA200701738A patent/EA018059B1/ru not_active IP Right Cessation
- 2006-02-14 US US11/816,383 patent/US8569499B2/en not_active Expired - Fee Related
- 2006-02-14 ZA ZA200705984A patent/ZA200705984B/xx unknown
- 2006-02-14 EP EP06706057A patent/EP1853574A1/en not_active Withdrawn
- 2006-02-14 JP JP2007554424A patent/JP5148289B2/ja not_active Expired - Fee Related
- 2006-02-14 CN CN2006800052071A patent/CN101137632B/zh not_active Expired - Fee Related
- 2006-02-14 CA CA2597615A patent/CA2597615C/en not_active Expired - Fee Related
- 2006-02-14 AR ARP060100517A patent/AR054735A1/es unknown
- 2006-02-14 AU AU2006215955A patent/AU2006215955B2/en not_active Ceased
- 2006-02-14 WO PCT/DK2006/000086 patent/WO2006086984A1/en active Application Filing
- 2006-02-14 BR BRPI0607438-3A patent/BRPI0607438A2/pt not_active IP Right Cessation
- 2006-02-14 UA UAA200710268A patent/UA106191C2/ru unknown
- 2006-02-15 MY MYPI20060625A patent/MY148242A/en unknown
-
2007
- 2007-07-12 IL IL184553A patent/IL184553A/en not_active IP Right Cessation
- 2007-09-12 NO NO20074642A patent/NO20074642L/no not_active Application Discontinuation
-
2008
- 2008-08-26 HK HK08109478.4A patent/HK1123544A1/xx not_active IP Right Cessation
-
2009
- 2009-11-24 US US12/625,178 patent/US20100069676A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN101137632B (zh) | 2013-06-19 |
AU2006215955B2 (en) | 2011-09-08 |
UA106191C2 (ru) | 2014-08-11 |
US8569499B2 (en) | 2013-10-29 |
NZ556517A (en) | 2010-05-28 |
IL184553A0 (en) | 2007-10-31 |
JP2008530038A (ja) | 2008-08-07 |
CN101137632A (zh) | 2008-03-05 |
AU2006215955A1 (en) | 2006-08-24 |
TW200716582A (en) | 2007-05-01 |
JP5148289B2 (ja) | 2013-02-20 |
CA2597615C (en) | 2014-05-27 |
WO2006086984A1 (en) | 2006-08-24 |
HK1123544A1 (en) | 2009-06-19 |
EA018059B1 (ru) | 2013-05-30 |
KR20070103386A (ko) | 2007-10-23 |
EA200701738A1 (ru) | 2007-12-28 |
US20100069676A1 (en) | 2010-03-18 |
TWI453198B (zh) | 2014-09-21 |
ZA200705984B (en) | 2009-01-28 |
AR054735A1 (es) | 2007-07-11 |
KR101364365B1 (ko) | 2014-02-21 |
CA2597615A1 (en) | 2006-08-24 |
EP1853574A1 (en) | 2007-11-14 |
MX2007009814A (es) | 2007-09-07 |
MY148242A (en) | 2013-03-29 |
US20080153847A1 (en) | 2008-06-26 |
BRPI0607438A2 (pt) | 2010-04-06 |
IL184553A (en) | 2014-05-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20074642L (no) | Fremgangsmate for a lage trans-1-((1R,3S)-6-klor-3-fenylindan-1-yl)-3,3-dimetylpiperazin | |
WO2005087771A3 (de) | 5,6-dialkyl-7-amino-triazolopyrimidine, verfahren zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen sowie sie enthaltende mittel | |
DK1474406T3 (da) | Disubstituerede thiazolylcarboxanilider samt deres anvendelse som mikrobicider | |
ATE441630T1 (de) | Substituierte cyclopenten-verbindungen | |
NO20060044L (no) | Fremgangsmate for fremstilling av substituerte 3-aryl-butyl-aminforbindelser | |
WO2006027705A3 (en) | Synthesis of triethylenetetramines | |
NO20065178L (no) | Tienopyridinderivater | |
WO2006123088A3 (en) | 4- (thiazol-2-ylthioalkyl) -pyrazoles and their use as herbicides | |
TW200624421A (en) | Method for preparing n-phenylpyrazole-1-carboxamides | |
NO330968B1 (no) | Ny fremgangsmate for syntesen av (1S)-4,5-dimetoksy-1-(metylaminometyl)-benzocyklobutan og addisjonssalter derav, og anvendelse i syntesen av ivabradin og addisjonssalter derav med en farmasoytisk akseptabel syre | |
ATE452882T1 (de) | Herstellung von quetiapin | |
WO2005105749A3 (en) | Process for making montelukast and intermediates therefor | |
WO2007057225A3 (en) | Process for making montelukast and intermediates therefor | |
NO20080157L (no) | Fremgangsmate for syntese av organiske forbindelser | |
NO20082116L (no) | Kjemisk fremgangsmate for fremstilling av en amido-fenoksybenzosyreforbindelse | |
WO2004099197A3 (de) | Substituierte oxyarene und deren verwendung zur bekämpfung von schädlingen | |
EA200600485A1 (ru) | Способ получения производных 2-оксо-1-пирролидина | |
NO20040388L (no) | Fremgangsmåte for fremstilling av beraprost og salter derav, samt forbindelser som er mellomprodukter i fremgangsmåten | |
ATE471312T1 (de) | Diaryltriazolmethylamin-derivate sowie ihre herstellung und therapeutische verwendung | |
WO2005087770A3 (de) | 5, 6-dihydrocarbyl-7-amino-triazolopyrimidine, verfahren zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen sowie sie enthaltende mittel | |
WO2005000804A3 (en) | Substituted indoles and a process for preparing substituted indoles | |
TW200700429A (en) | Process for production of glucopyranosyloxypyrazole derivative | |
WO2004013122A3 (de) | Oktupolare moleküle als organische halbleiter | |
DK1807401T3 (da) | Fremgangsmåde til fremstilling af phenyl-2-pyrimidinylketoner samt deres nye mellemprodukter | |
WO2003106440A3 (en) | PROCESS FOR THE SYNTHESIS OF A BENZAMIDE DERIVATIVE |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
CREP | Change of representative |
Representative=s name: PLOUGMANN & VINGTOFT, POSTBOKS 1003 SENTRUM, 0104 |
|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |