ATE463568T1 - Neue aldolasen und verfahren zur herstellung von substituierter alpha-ketosäure - Google Patents

Neue aldolasen und verfahren zur herstellung von substituierter alpha-ketosäure

Info

Publication number
ATE463568T1
ATE463568T1 AT03792838T AT03792838T ATE463568T1 AT E463568 T1 ATE463568 T1 AT E463568T1 AT 03792838 T AT03792838 T AT 03792838T AT 03792838 T AT03792838 T AT 03792838T AT E463568 T1 ATE463568 T1 AT E463568T1
Authority
AT
Austria
Prior art keywords
aldolases
new
keto acid
substituted alpha
producing substituted
Prior art date
Application number
AT03792838T
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English (en)
Inventor
Masakazu Sugiyama
Kunihiko Watanabe
Original Assignee
Ajinomoto Kk
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Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of ATE463568T1 publication Critical patent/ATE463568T1/de

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • C12P7/50Polycarboxylic acids having keto groups, e.g. 2-ketoglutaric acid

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Lubricants (AREA)
AT03792838T 2002-08-26 2003-08-26 Neue aldolasen und verfahren zur herstellung von substituierter alpha-ketosäure ATE463568T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2002245980 2002-08-26
JP2003171299 2003-06-16
PCT/JP2003/010750 WO2004018672A1 (ja) 2002-08-26 2003-08-26 新規アルドラーゼおよび置換α−ケト酸の製造方法

Publications (1)

Publication Number Publication Date
ATE463568T1 true ATE463568T1 (de) 2010-04-15

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AT03792838T ATE463568T1 (de) 2002-08-26 2003-08-26 Neue aldolasen und verfahren zur herstellung von substituierter alpha-ketosäure

Country Status (12)

Country Link
US (6) US7351569B2 (de)
EP (3) EP2210943A1 (de)
JP (2) JP4670347B2 (de)
KR (1) KR100741650B1 (de)
CN (2) CN103525847A (de)
AT (1) ATE463568T1 (de)
AU (1) AU2003261722A1 (de)
CA (2) CA2484871C (de)
DE (1) DE60332026D1 (de)
DK (1) DK1533376T3 (de)
RU (1) RU2307871C2 (de)
WO (1) WO2004018672A1 (de)

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US8058038B2 (en) 2011-11-15
US8697416B2 (en) 2014-04-15
CN1678742B (zh) 2013-07-17
US20120040416A1 (en) 2012-02-16
JPWO2004018672A1 (ja) 2005-12-08
CA2714881C (en) 2012-10-23
RU2307871C2 (ru) 2007-10-10
CA2484871C (en) 2010-11-30
CA2484871A1 (en) 2004-03-04
JP2010284170A (ja) 2010-12-24
KR100741650B1 (ko) 2007-07-24
EP1533376B1 (de) 2010-04-07
CA2714881A1 (en) 2004-03-04
KR20050058516A (ko) 2005-06-16
US20050153405A1 (en) 2005-07-14
EP1533376A1 (de) 2005-05-25
DE60332026D1 (de) 2010-05-20
RU2005108605A (ru) 2005-10-27
EP1533376A4 (de) 2006-09-06
CN103525847A (zh) 2014-01-22
US7351569B2 (en) 2008-04-01
EP2280068A1 (de) 2011-02-02
US20100279365A1 (en) 2010-11-04
WO2004018672A1 (ja) 2004-03-04
US20080318290A1 (en) 2008-12-25
US20130157342A1 (en) 2013-06-20
US8273556B2 (en) 2012-09-25
EP2210943A1 (de) 2010-07-28
CN1678742A (zh) 2005-10-05
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US20130252310A1 (en) 2013-09-26
JP4670347B2 (ja) 2011-04-13
AU2003261722A1 (en) 2004-03-11

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