DE60303825D1 - Verfahren zur herstellung von enantiomeren von indol-2,3-dion-3-oximderivaten - Google Patents
Verfahren zur herstellung von enantiomeren von indol-2,3-dion-3-oximderivatenInfo
- Publication number
- DE60303825D1 DE60303825D1 DE60303825T DE60303825T DE60303825D1 DE 60303825 D1 DE60303825 D1 DE 60303825D1 DE 60303825 T DE60303825 T DE 60303825T DE 60303825 T DE60303825 T DE 60303825T DE 60303825 D1 DE60303825 D1 DE 60303825D1
- Authority
- DE
- Germany
- Prior art keywords
- dion
- indol
- preparing enantiomers
- derivatives
- oxim
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200201237 | 2002-08-22 | ||
| DK200201237 | 2002-08-22 | ||
| PCT/DK2003/000539 WO2004018466A2 (en) | 2002-08-22 | 2003-08-13 | A method of preparing enantiomers of indole-2,3-dione-3-oxime derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60303825D1 true DE60303825D1 (de) | 2006-04-27 |
| DE60303825T2 DE60303825T2 (de) | 2006-08-17 |
Family
ID=31896777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60303825T Expired - Lifetime DE60303825T2 (de) | 2002-08-22 | 2003-08-13 | Verfahren zum herstellen von enantiomeren von indol-2,3-dion-3-oxim-derivaten |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7632948B2 (de) |
| EP (1) | EP1532146B1 (de) |
| JP (1) | JP2006503011A (de) |
| CN (1) | CN1296372C (de) |
| AT (1) | ATE318815T1 (de) |
| AU (1) | AU2003250323A1 (de) |
| CA (1) | CA2493244A1 (de) |
| DE (1) | DE60303825T2 (de) |
| DK (1) | DK1532146T3 (de) |
| MX (1) | MXPA05002056A (de) |
| NZ (1) | NZ537810A (de) |
| WO (1) | WO2004018466A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2369746A1 (en) | 1999-05-19 | 2000-11-30 | Neurosearch A/S | Inhibitors of proton-gated cation channels and their use in the treatment of ischaemic disorders |
| PE20061413A1 (es) * | 2005-04-29 | 2007-01-20 | Wyeth Corp | Proceso para preparar isatinas con control de formacion de subproductos |
| AU2006317545B2 (en) | 2005-11-23 | 2012-04-12 | Aros Pharma Aps | Compositions and methods for modulating gated ion channels |
| CA2652307A1 (en) * | 2006-04-10 | 2007-10-18 | Painceptor Pharma Corporation | Compositions and methods for modulating gated ion channels |
| WO2008144931A1 (en) * | 2007-05-30 | 2008-12-04 | Painceptor Pharma Corporation | Compositions and methods for modulating gated ion channels |
| CN112451682A (zh) | 2015-11-25 | 2021-03-09 | 乐高化学生物科学股份有限公司 | 包含自降解基团的缀合物及其相关方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2542941B2 (ja) * | 1990-02-02 | 1996-10-09 | チッソ株式会社 | 光学活性ヒドロキシラクトン類の製造方法 |
| JP2939646B2 (ja) | 1990-07-17 | 1999-08-25 | チッソ株式会社 | ４―置換―２―ヒドロキシブタン酸エステルおよび製造法 |
| JP3789951B2 (ja) * | 1993-11-25 | 2006-06-28 | 三共アグロ株式会社 | Ｏ−ｎ結合を有する糖誘導体及び製造方法 |
| UA54403C2 (uk) * | 1996-10-01 | 2003-03-17 | Н'Юросерч А/С | Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму |
| WO1999049864A1 (en) * | 1998-03-31 | 1999-10-07 | Neurosearch A/S | Indole-2,3-dione-3-oxime derivatives for therapeutic use |
| AU7418100A (en) | 1999-09-08 | 2001-04-10 | Lonza A.G. | Method for producing (r) or (s)-hydroxy-gamma-butyrolactone |
-
2003
- 2003-08-13 MX MXPA05002056A patent/MXPA05002056A/es active IP Right Grant
- 2003-08-13 WO PCT/DK2003/000539 patent/WO2004018466A2/en active IP Right Grant
- 2003-08-13 JP JP2004529729A patent/JP2006503011A/ja active Pending
- 2003-08-13 AU AU2003250323A patent/AU2003250323A1/en not_active Abandoned
- 2003-08-13 AT AT03792147T patent/ATE318815T1/de not_active IP Right Cessation
- 2003-08-13 EP EP03792147A patent/EP1532146B1/de not_active Expired - Lifetime
- 2003-08-13 US US10/524,441 patent/US7632948B2/en not_active Expired - Fee Related
- 2003-08-13 CN CNB03818396XA patent/CN1296372C/zh not_active Expired - Fee Related
- 2003-08-13 DK DK03792147T patent/DK1532146T3/da active
- 2003-08-13 NZ NZ537810A patent/NZ537810A/en unknown
- 2003-08-13 DE DE60303825T patent/DE60303825T2/de not_active Expired - Lifetime
- 2003-08-13 CA CA002493244A patent/CA2493244A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US7632948B2 (en) | 2009-12-15 |
| JP2006503011A (ja) | 2006-01-26 |
| WO2004018466A3 (en) | 2004-03-25 |
| EP1532146A2 (de) | 2005-05-25 |
| ATE318815T1 (de) | 2006-03-15 |
| CN1296372C (zh) | 2007-01-24 |
| WO2004018466A2 (en) | 2004-03-04 |
| DK1532146T3 (da) | 2006-07-03 |
| AU2003250323A1 (en) | 2004-03-11 |
| EP1532146B1 (de) | 2006-03-01 |
| MXPA05002056A (es) | 2005-06-08 |
| DE60303825T2 (de) | 2006-08-17 |
| CN1671704A (zh) | 2005-09-21 |
| CA2493244A1 (en) | 2004-03-04 |
| US20060178391A1 (en) | 2006-08-10 |
| NZ537810A (en) | 2006-10-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |