ATE502045T1 - Verfahren zur herstellung von perindoprilerbumin - Google Patents

Verfahren zur herstellung von perindoprilerbumin

Info

Publication number
ATE502045T1
ATE502045T1 AT06776747T AT06776747T ATE502045T1 AT E502045 T1 ATE502045 T1 AT E502045T1 AT 06776747 T AT06776747 T AT 06776747T AT 06776747 T AT06776747 T AT 06776747T AT E502045 T1 ATE502045 T1 AT E502045T1
Authority
AT
Austria
Prior art keywords
perindoprilerbumin
producing
preparation
relates
present
Prior art date
Application number
AT06776747T
Other languages
English (en)
Inventor
Zoran Ham
Borut Furlan
Original Assignee
Lek Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals filed Critical Lek Pharmaceuticals
Application granted granted Critical
Publication of ATE502045T1 publication Critical patent/ATE502045T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
AT06776747T 2005-08-12 2006-08-10 Verfahren zur herstellung von perindoprilerbumin ATE502045T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI200500232 2005-08-12
PCT/EP2006/007926 WO2007020012A1 (en) 2005-08-12 2006-08-10 A process for the preparation of perindopril erbumine

Publications (1)

Publication Number Publication Date
ATE502045T1 true ATE502045T1 (de) 2011-04-15

Family

ID=37036996

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06776747T ATE502045T1 (de) 2005-08-12 2006-08-10 Verfahren zur herstellung von perindoprilerbumin

Country Status (13)

Country Link
US (1) US20100016614A1 (de)
EP (1) EP1943267B1 (de)
JP (1) JP4923050B2 (de)
CN (1) CN101228179B (de)
AT (1) ATE502045T1 (de)
AU (1) AU2006281684B2 (de)
BR (1) BRPI0614622A2 (de)
CA (1) CA2618561C (de)
DE (1) DE602006020760D1 (de)
EA (1) EA014773B1 (de)
MX (1) MX2008002064A (de)
UA (1) UA92613C2 (de)
WO (1) WO2007020012A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008114270A1 (en) * 2007-03-22 2008-09-25 Aarti Healthcare Limited Process for the preparation of perindopril erbumine salt and novel polymorph (s) thereof
SI22543A (sl) * 2007-06-27 2008-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove soli perindoprila
CN103822996A (zh) * 2014-03-20 2014-05-28 东英（江苏）药业有限公司 一种培哚普利叔丁胺盐含量的测定方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2811319B1 (fr) * 2000-07-06 2002-08-23 Adir Nouvelle forme cristalline beta du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2811320B1 (fr) * 2000-07-06 2002-08-23 Adir Nouvelle forme cristalline alpha du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2811318B1 (fr) * 2000-07-06 2002-08-23 Adir Nouvelle forme cristalline gamma du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
PT1333026E (pt) * 2002-01-30 2007-09-17 Servier Lab ''processo para a preparação de perindopril com elevado grau de pureza e intermediários úteis para a sua síntese''
GB2395195A (en) * 2002-11-18 2004-05-19 Cipla Ltd Preparation of perindopril from carboxy-protected precursor, & perindopril monohydrates for use as angiotensin converting enzyme (ACE) inhibitors
DE60300581T2 (de) * 2003-03-12 2006-01-19 Les Laboratoires Servier Verfahren für die Synthese von Perindopril und seiner pharmazeutisch annehmba- ren Salzen
DK1636185T3 (da) * 2003-06-24 2012-05-07 Servier Lab Nye krystalformer af Perindopril erbumin
US20050171165A1 (en) * 2003-11-12 2005-08-04 Bhirud Shekhar B. Process for the preparation of perindopril
EP1910287B1 (de) * 2005-07-25 2012-03-14 LEK Pharmaceuticals d.d. Verfahren zur herstellung von kristallinem perindopril
US20090099370A1 (en) * 2005-08-12 2009-04-16 Sandoz Ag Crystalline Form of Perindopril Erbumine

Also Published As

Publication number Publication date
JP4923050B2 (ja) 2012-04-25
AU2006281684A1 (en) 2007-02-22
UA92613C2 (ru) 2010-11-25
CN101228179A (zh) 2008-07-23
BRPI0614622A2 (pt) 2011-04-12
EP1943267B1 (de) 2011-03-16
MX2008002064A (es) 2008-04-17
WO2007020012A1 (en) 2007-02-22
EA200800466A1 (ru) 2008-06-30
EP1943267A1 (de) 2008-07-16
CA2618561C (en) 2014-04-29
JP2009504595A (ja) 2009-02-05
US20100016614A1 (en) 2010-01-21
CN101228179B (zh) 2011-02-02
EA014773B1 (ru) 2011-02-28
CA2618561A1 (en) 2007-02-22
DE602006020760D1 (de) 2011-04-28
AU2006281684B2 (en) 2012-08-02

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Legal Events

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