ATE546458T1 - Verfahren zur herstellung von 6-alpha, 9-alpha- - Google Patents

Verfahren zur herstellung von 6-alpha, 9-alpha-

Info

Publication number
ATE546458T1
ATE546458T1 AT07730112T AT07730112T ATE546458T1 AT E546458 T1 ATE546458 T1 AT E546458T1 AT 07730112 T AT07730112 T AT 07730112T AT 07730112 T AT07730112 T AT 07730112T AT E546458 T1 ATE546458 T1 AT E546458T1
Authority
AT
Austria
Prior art keywords
alpha
compound
formula
producing
intermediates
Prior art date
Application number
AT07730112T
Other languages
English (en)
Inventor
Malcolm Berry
Mark Hughes
David Parry-Jones
Stephen Skittrall
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE546458T1 publication Critical patent/ATE546458T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Catalysts (AREA)
AT07730112T 2006-06-16 2007-06-13 Verfahren zur herstellung von 6-alpha, 9-alpha- ATE546458T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0612027.3A GB0612027D0 (en) 2006-06-16 2006-06-16 Novel process
PCT/EP2007/055805 WO2007144363A2 (en) 2006-06-16 2007-06-13 Process for the preparation of 6-alpha, 9-alpha-difluoro-17-alpha - ((2-furanylcarbonyl)oxy)-11-beta -hydroxy-16-alpha -methyl-s-oxo-androsta-1,4-diene-17-beta- -carbothioic acid s-fluoromethyl

Publications (1)

Publication Number Publication Date
ATE546458T1 true ATE546458T1 (de) 2012-03-15

Family

ID=36775829

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07730112T ATE546458T1 (de) 2006-06-16 2007-06-13 Verfahren zur herstellung von 6-alpha, 9-alpha-

Country Status (7)

Country Link
US (1) US8309713B2 (de)
EP (1) EP2044098B1 (de)
JP (2) JP5568299B2 (de)
AT (1) ATE546458T1 (de)
ES (1) ES2379016T3 (de)
GB (1) GB0612027D0 (de)
WO (1) WO2007144363A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2611821A2 (de) 2010-09-01 2013-07-10 Cadila Healthcare Limited Verfahren zur herstellung von fluticasonpropionat/-furoat
CN102558273B (zh) 2010-12-14 2014-07-02 浙江省天台县奥锐特药业有限公司 氟替卡松糠酸酯的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA81976B (en) * 1980-02-15 1982-07-28 Glaxo Group Ltd Androstane carbothioates
GB0017988D0 (en) 2000-07-21 2000-09-13 Glaxo Group Ltd Novel process
EA005992B1 (ru) * 2000-08-05 2005-08-25 Глаксо Груп Лимитед S-ФТОРМЕТИЛОВЫЙ ЭФИР 6α,9α-ДИФТОР-17α-[(2-ФУРАНИЛКАРБОНИЛ)ОКСИ]-11β-ГИДРОКСИ-16α-МЕТИЛ-3-ОКСОАНДРОСТА-1,4-ДИЕН-17β-КАРБОТИОКИСЛОТЫ В КАЧЕСТВЕ ПРОТИВОВОСПАЛИТЕЛЬНОГО АГЕНТА

Also Published As

Publication number Publication date
WO2007144363A3 (en) 2008-05-02
EP2044098A2 (de) 2009-04-08
JP2009539934A (ja) 2009-11-19
US20090118495A1 (en) 2009-05-07
US8309713B2 (en) 2012-11-13
JP5568299B2 (ja) 2014-08-06
JP2014177482A (ja) 2014-09-25
EP2044098B1 (de) 2012-02-22
WO2007144363A2 (en) 2007-12-21
ES2379016T3 (es) 2012-04-19
GB0612027D0 (en) 2006-07-26

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