ATE519765T1 - Verfahren zur herstellung von 3-hydroxymorphinan- derivaten - Google Patents

Verfahren zur herstellung von 3-hydroxymorphinan- derivaten

Info

Publication number
ATE519765T1
ATE519765T1 AT09717537T AT09717537T ATE519765T1 AT E519765 T1 ATE519765 T1 AT E519765T1 AT 09717537 T AT09717537 T AT 09717537T AT 09717537 T AT09717537 T AT 09717537T AT E519765 T1 ATE519765 T1 AT E519765T1
Authority
AT
Austria
Prior art keywords
producing
derivatives
hydroxymorphinan
hydroxymorphinan derivatives
methoxymorphinan
Prior art date
Application number
AT09717537T
Other languages
English (en)
Inventor
Peter Wang
Tao Jiang
Gary Cantrell
David Berberich
Frank Moser
Jian Bao
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Application granted granted Critical
Publication of ATE519765T1 publication Critical patent/ATE519765T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
AT09717537T 2008-02-29 2009-02-18 Verfahren zur herstellung von 3-hydroxymorphinan- derivaten ATE519765T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3243508P 2008-02-29 2008-02-29
PCT/US2009/034343 WO2009111162A1 (en) 2008-02-29 2009-02-18 Process for the preparation of 3-hydroxymorphinan derivatives

Publications (1)

Publication Number Publication Date
ATE519765T1 true ATE519765T1 (de) 2011-08-15

Family

ID=40580910

Family Applications (1)

Application Number Title Priority Date Filing Date
AT09717537T ATE519765T1 (de) 2008-02-29 2009-02-18 Verfahren zur herstellung von 3-hydroxymorphinan- derivaten

Country Status (5)

Country Link
US (1) US7999105B2 (de)
EP (2) EP2250175B1 (de)
AT (1) ATE519765T1 (de)
CA (1) CA2716944A1 (de)
WO (1) WO2009111162A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2784690T3 (es) 2013-12-05 2020-09-29 Univ Bath Nuevos compuestos opioides y sus usos
ES2701855T3 (es) 2016-05-31 2019-02-26 Alcaliber Investig Desarrollo E Innovacion Slu Proceso para la obtención de 3,14-diacetiloximorfona a partir de oripavina
SK592017A3 (sk) 2017-07-04 2019-01-08 Saneca Pharmaceuticals A. S. Spôsob prípravy morfínanových zlúčenín

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4451470A (en) * 1982-07-06 1984-05-29 E. I. Du Pont De Nemours And Company Analgesic, antagonist, and/or anorectic 14-fluoromorphinans
US5869669A (en) * 1996-07-26 1999-02-09 Penick Corporation Preparation of 14-hydroxynormorphinones from normorphinone dienol acylates
AU6520198A (en) * 1997-03-31 1998-10-22 Toray Industries, Inc. Quinolinomorphinane derivatives and medicinal use thereof
US6177567B1 (en) 1999-10-15 2001-01-23 Boehringer Ingelheim Chemicals, Inc. Method for preparing oxycodone
US6864370B1 (en) * 2003-06-05 2005-03-08 Zhaiwei Lin Process for manufacturing oxycodone
GB0421149D0 (en) * 2004-09-23 2004-10-27 Johnson Matthey Plc Preparation of oxycodone

Also Published As

Publication number Publication date
US20090221825A1 (en) 2009-09-03
EP2319845A1 (de) 2011-05-11
EP2250175A1 (de) 2010-11-17
EP2319845B1 (de) 2013-07-24
EP2250175B1 (de) 2011-08-10
US7999105B2 (en) 2011-08-16
WO2009111162A1 (en) 2009-09-11
CA2716944A1 (en) 2009-09-11

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Legal Events

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