ATE375355T1 - Verfahren zur herstellung von cefpodoxim-proxetil - Google Patents
Verfahren zur herstellung von cefpodoxim-proxetilInfo
- Publication number
- ATE375355T1 ATE375355T1 AT02808277T AT02808277T ATE375355T1 AT E375355 T1 ATE375355 T1 AT E375355T1 AT 02808277 T AT02808277 T AT 02808277T AT 02808277 T AT02808277 T AT 02808277T AT E375355 T1 ATE375355 T1 AT E375355T1
- Authority
- AT
- Austria
- Prior art keywords
- producing
- proxetil
- cefpodoxim
- cefpodoxim proxetil
- preparation
- Prior art date
Links
- LTINZAODLRIQIX-ZFEISNGRSA-N 1-propan-2-yloxycarbonyloxyethyl (6r,7r)-7-[[(2e)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Chemical compound N([C@H]1[C@@H]2N(C1=O)C(=C(CS2)COC)C(=O)OC(C)OC(=O)OC(C)C)C(=O)C(=N\OC)\C1=CSC(N)=N1 LTINZAODLRIQIX-ZFEISNGRSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- LTINZAODLRIQIX-FBXRGJNPSA-N cefpodoxime proxetil Chemical compound N([C@H]1[C@@H]2N(C1=O)C(=C(CS2)COC)C(=O)OC(C)OC(=O)OC(C)C)C(=O)C(=N/OC)\C1=CSC(N)=N1 LTINZAODLRIQIX-FBXRGJNPSA-N 0.000 abstract 1
- 229960004797 cefpodoxime proxetil Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IN2002/000240 WO2004056834A1 (en) | 2002-12-20 | 2002-12-20 | A process for the preparation of cefpodoxime proxetil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE375355T1 true ATE375355T1 (de) | 2007-10-15 |
Family
ID=32676746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02808277T ATE375355T1 (de) | 2002-12-20 | 2002-12-20 | Verfahren zur herstellung von cefpodoxim-proxetil |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20060293296A1 (de) |
| EP (1) | EP1590353B1 (de) |
| AT (1) | ATE375355T1 (de) |
| AU (1) | AU2002368494A1 (de) |
| DE (1) | DE60222945T2 (de) |
| ES (1) | ES2291547T3 (de) |
| WO (1) | WO2004056834A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060009639A1 (en) * | 2002-11-22 | 2006-01-12 | Orchid Chemicals & Pharmaceuticals Limited | Process for the preparation of cefpodoxime proxetil |
| WO2010097675A1 (en) | 2009-02-27 | 2010-09-02 | Dhanuka Laboratories Ltd. | An improved preparation process for cefpodoxime proxetil |
| EP2520578A1 (de) * | 2011-05-06 | 2012-11-07 | Lupin Limited | Verfahren zur Reinigung von Cephalosporinen |
| CN108530468A (zh) * | 2018-03-21 | 2018-09-14 | 山东睿鹰先锋制药有限公司 | 一种头孢泊肟酯杂质及其制备方法和应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4486425A (en) * | 1980-09-30 | 1984-12-04 | Sankyo Company Limited | 7-[2-(2-Aminothiazol-4-yl)-2-(syn)-methoxyiminoacetamido]-3-methoxymethyl-3-cephem-4-carboxylates |
| US4400503A (en) * | 1981-10-30 | 1983-08-23 | Eli Lilly And Company | Purification of syn-7-[[(2-amino-4-thiazolyl)(methoxyimino) acetyl]amino]-3-methyl-3-cephem-4-carboxylic acid |
| JPS5896091A (ja) * | 1981-12-01 | 1983-06-07 | Sankyo Co Ltd | ３−アルコキシメチルセフアロスポリン類の製造法 |
| YU48484B (sh) * | 1991-05-24 | 1998-09-18 | Hoechst Aktiengesellschaft | Kristalne kiselinske adicione soli diastereomerno čistih 1-(2,2-dimetilpropioniloksi)-etilestara 3-cefem-4-karbonske kiseline |
| DK0531875T3 (da) * | 1991-09-07 | 2004-06-21 | Aventis Pharma Gmbh | Diastereomer af 3-cephem-4-carboxylsyre-1-(-isopropoxycarbonyloxy)-ethylester og fremgangsmåde til dens fremstilling |
| AT413383B (de) * | 1998-01-09 | 2006-02-15 | Sandoz Ag | Verfahren zur isolierung eines diastereoisomerengemisches von cefpodoxim proxetil |
| AT408226B (de) * | 1999-05-05 | 2001-09-25 | Biochemie Gmbh | Kristalliner 7-(2-(2-formylaminothiazol-4-yl)-2 |
| KR100342944B1 (ko) * | 1999-11-08 | 2002-07-02 | 민경윤 | 고순도 세프포독심 프록세틸의 제조방법 |
| IT1317735B1 (it) * | 2000-01-26 | 2003-07-15 | Nicox Sa | Sali di agenti antimicrobici. |
| WO2002068429A1 (en) * | 2001-02-27 | 2002-09-06 | Ranbaxy Laboratories Limited | Process for the preparation of cefpodoxime proxetil |
| WO2002083634A2 (en) * | 2001-04-17 | 2002-10-24 | Ranbaxy Laboratories Limited | Process for the preparation of cefpodoxime acid |
| WO2004060896A1 (en) * | 2003-01-06 | 2004-07-22 | Lupin Limited | A process for the manufacture of cefpodoxime proxetil |
-
2002
- 2002-12-20 EP EP02808277A patent/EP1590353B1/de not_active Expired - Lifetime
- 2002-12-20 ES ES02808277T patent/ES2291547T3/es not_active Expired - Lifetime
- 2002-12-20 AT AT02808277T patent/ATE375355T1/de not_active IP Right Cessation
- 2002-12-20 DE DE60222945T patent/DE60222945T2/de not_active Expired - Lifetime
- 2002-12-20 US US10/539,525 patent/US20060293296A1/en not_active Abandoned
- 2002-12-20 WO PCT/IN2002/000240 patent/WO2004056834A1/en not_active Ceased
- 2002-12-20 AU AU2002368494A patent/AU2002368494A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE60222945D1 (de) | 2007-11-22 |
| EP1590353A1 (de) | 2005-11-02 |
| EP1590353B1 (de) | 2007-10-10 |
| WO2004056834A1 (en) | 2004-07-08 |
| AU2002368494A1 (en) | 2004-07-14 |
| ES2291547T3 (es) | 2008-03-01 |
| US20060293296A1 (en) | 2006-12-28 |
| DE60222945T2 (de) | 2008-02-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |