EA200800411A1 - Новая кристаллическая форма периндоприлэрбумина - Google Patents

Новая кристаллическая форма периндоприлэрбумина

Info

Publication number
EA200800411A1
EA200800411A1 EA200800411A EA200800411A EA200800411A1 EA 200800411 A1 EA200800411 A1 EA 200800411A1 EA 200800411 A EA200800411 A EA 200800411A EA 200800411 A EA200800411 A EA 200800411A EA 200800411 A1 EA200800411 A1 EA 200800411A1
Authority
EA
Eurasian Patent Office
Prior art keywords
perindoprilerbumina
crystal form
new crystal
new
perindopril
Prior art date
Application number
EA200800411A
Other languages
English (en)
Inventor
Ульрих Гриссер
Верена Нидервангер
Original Assignee
Сандоз Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Сандоз Аг filed Critical Сандоз Аг
Publication of EA200800411A1 publication Critical patent/EA200800411A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

В заявке описана новая кристаллическая форма ингибитора ангиотензинконвертирующего фермента периндоприла и способы ее получения.
EA200800411A 2005-08-12 2006-08-10 Новая кристаллическая форма периндоприлэрбумина EA200800411A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI200500231 2005-08-12
PCT/EP2006/007923 WO2007020009A1 (en) 2005-08-12 2006-08-10 New crystalline form of perindopril erbumine

Publications (1)

Publication Number Publication Date
EA200800411A1 true EA200800411A1 (ru) 2008-08-29

Family

ID=37478710

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200800411A EA200800411A1 (ru) 2005-08-12 2006-08-10 Новая кристаллическая форма периндоприлэрбумина

Country Status (10)

Country Link
US (1) US20090099370A1 (ru)
EP (1) EP1942886A1 (ru)
JP (1) JP2009505970A (ru)
CN (1) CN101227902A (ru)
AU (1) AU2006281681A1 (ru)
CA (1) CA2618516A1 (ru)
EA (1) EA200800411A1 (ru)
MX (1) MX2008002066A (ru)
WO (1) WO2007020009A1 (ru)
ZA (1) ZA200800432B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2008002064A (es) * 2005-08-12 2008-04-17 Lek Pharmaceuticals Un proceso para la preparacion de perindopril-erbumina.
AU2013201812B2 (en) * 2007-06-27 2015-04-02 Les Laboratoires Servier Salts of perindopril
SI22543A (sl) * 2007-06-27 2008-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove soli perindoprila
PT105315B (pt) 2010-09-29 2013-01-16 Inst Superior Tecnico Uma nova forma cristalina hidratada de erbumina de perindopril, métodos para a sua preparação e sua utilização em preparações farmacêuticas
FR2985511B1 (fr) * 2012-01-05 2014-01-03 Servier Lab Forme cristalline delta du sel d'arginine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
WO2016178591A2 (en) 2015-05-05 2016-11-10 Gene Predit, Sa Genetic markers and treatment of male obesity

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2811319B1 (fr) * 2000-07-06 2002-08-23 Adir Nouvelle forme cristalline beta du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2811320B1 (fr) * 2000-07-06 2002-08-23 Adir Nouvelle forme cristalline alpha du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2811318B1 (fr) * 2000-07-06 2002-08-23 Adir Nouvelle forme cristalline gamma du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
GB2395195A (en) * 2002-11-18 2004-05-19 Cipla Ltd Preparation of perindopril from carboxy-protected precursor, & perindopril monohydrates for use as angiotensin converting enzyme (ACE) inhibitors
KR20060035636A (ko) * 2003-06-24 2006-04-26 르 라보레또레 쎄르비에르 신규한 결정형의 페린도프릴 에르부민
BR0318561A (pt) * 2003-10-21 2006-10-10 Lupin Ltd processo seletivo para a preparação de erbumino perindopril cristalino
ES2329923T3 (es) * 2005-03-14 2009-12-02 Les Laboratoires Servier Procedimiento mejorado para la purificacion de perindopril.
ATE549315T1 (de) * 2005-07-25 2012-03-15 Lek Pharmaceuticals Verfahren zur herstellung von kristallinem perindopril

Also Published As

Publication number Publication date
CN101227902A (zh) 2008-07-23
MX2008002066A (es) 2008-04-16
ZA200800432B (en) 2008-12-31
CA2618516A1 (en) 2007-02-22
EP1942886A1 (en) 2008-07-16
AU2006281681A1 (en) 2007-02-22
US20090099370A1 (en) 2009-04-16
WO2007020009A1 (en) 2007-02-22
JP2009505970A (ja) 2009-02-12

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