DE60225701T2 - Ophthalmische depot-formulierungen zur periokkularen oder subkonjunktivalen verabreichung - Google Patents

Ophthalmische depot-formulierungen zur periokkularen oder subkonjunktivalen verabreichung Download PDF

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Publication number
DE60225701T2
DE60225701T2 DE60225701T DE60225701T DE60225701T2 DE 60225701 T2 DE60225701 T2 DE 60225701T2 DE 60225701 T DE60225701 T DE 60225701T DE 60225701 T DE60225701 T DE 60225701T DE 60225701 T2 DE60225701 T2 DE 60225701T2
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Germany
Prior art keywords
use according
active ingredient
formulation
microparticles
polymer
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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DE60225701T
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German (de)
English (en)
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DE60225701D1 (de
Inventor
Markus Ahlheim
Michael Ausborn
David Bodmer
Christian Schoch
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Novartis AG
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Novartis AG
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Publication of DE60225701D1 publication Critical patent/DE60225701D1/de
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Publication of DE60225701T2 publication Critical patent/DE60225701T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60225701T 2001-09-14 2002-09-13 Ophthalmische depot-formulierungen zur periokkularen oder subkonjunktivalen verabreichung Expired - Lifetime DE60225701T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0122318.9A GB0122318D0 (en) 2001-09-14 2001-09-14 Organic compounds
GB0122318 2001-09-14
PCT/EP2002/010314 WO2003024420A1 (en) 2001-09-14 2002-09-13 Ophthalmic depot formulations for periocular or subconjunctival administration

Publications (2)

Publication Number Publication Date
DE60225701D1 DE60225701D1 (de) 2008-04-30
DE60225701T2 true DE60225701T2 (de) 2009-04-30

Family

ID=9922147

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60225701T Expired - Lifetime DE60225701T2 (de) 2001-09-14 2002-09-13 Ophthalmische depot-formulierungen zur periokkularen oder subkonjunktivalen verabreichung

Country Status (24)

Country Link
US (4) US20040234611A1 (https=)
EP (1) EP1429725B1 (https=)
JP (3) JP2005504797A (https=)
KR (1) KR20040030869A (https=)
CN (2) CN102008428A (https=)
AT (1) ATE389385T1 (https=)
AU (1) AU2002342694B2 (https=)
BR (1) BR0212475A (https=)
CA (1) CA2455680C (https=)
CO (1) CO5560548A2 (https=)
DE (1) DE60225701T2 (https=)
EC (1) ECSP044967A (https=)
ES (1) ES2302849T3 (https=)
GB (1) GB0122318D0 (https=)
HU (1) HU229453B1 (https=)
IL (2) IL160027A0 (https=)
MX (1) MXPA04002421A (https=)
NO (1) NO333825B1 (https=)
NZ (1) NZ531481A (https=)
PL (1) PL203949B1 (https=)
PT (1) PT1429725E (https=)
RU (1) RU2316315C2 (https=)
WO (1) WO2003024420A1 (https=)
ZA (1) ZA200400524B (https=)

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RU2316315C2 (ru) 2008-02-10
US20120269894A1 (en) 2012-10-25
CN102008428A (zh) 2011-04-13
PT1429725E (pt) 2008-06-18
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EP1429725B1 (en) 2008-03-19
IL160027A0 (en) 2004-06-20
HUP0401568A2 (hu) 2004-11-29
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AU2002342694B2 (en) 2006-08-24
DE60225701D1 (de) 2008-04-30
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US20130122064A1 (en) 2013-05-16
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