BR112014017969A8 - Microesferas ou micropartículas bioerodíveis ou bio-degradáveis liberadas por tempo suspensas em uma formulação de droga injetável de formação de depósito - Google Patents
Microesferas ou micropartículas bioerodíveis ou bio-degradáveis liberadas por tempo suspensas em uma formulação de droga injetável de formação de depósitoInfo
- Publication number
- BR112014017969A8 BR112014017969A8 BR112014017969A BR112014017969A BR112014017969A8 BR 112014017969 A8 BR112014017969 A8 BR 112014017969A8 BR 112014017969 A BR112014017969 A BR 112014017969A BR 112014017969 A BR112014017969 A BR 112014017969A BR 112014017969 A8 BR112014017969 A8 BR 112014017969A8
- Authority
- BR
- Brazil
- Prior art keywords
- deposit
- bioerodible
- drug formulation
- microparticles
- injection drug
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Abstract
MICROESFERAS OU MICROPARTÍCULAS BIOERODÍVEIS OU BIODEGRADÁVEIS LIBERADAS POR TEMPO SUSPENSAS EM UMA FORMULAÇÃO DE FÁRMACO INJETÁVEL DE FORMAÇÃO DE DEPÓSITO. Um material compósito de distribuição de fármaco pode ser injetado no olho de um ser humano ou mamífero para fornecer distribuição sustentada do fármaco. Um material compósito de distribuição de fármaco pode incluir uma pluralidade de micropartículas dispersas em uma composição de meios. As micropartículas podem conter um fármaco e um revestimento compreendendo um material bioerodível ou um material biodegradável, e a composição de meios inclui o fármaco dispersado em um material de formação de depósito. A composição de meios pode se tornar gel ou solidificar após injeção dentro do olho.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261589681P | 2012-01-23 | 2012-01-23 | |
PCT/US2013/022466 WO2013112434A1 (en) | 2012-01-23 | 2013-01-22 | Time released biodegradable or bioerodible microspheres or microparticles suspended in a solidifying depot-forming injectable drug formulation |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112014017969A2 BR112014017969A2 (pt) | 2017-06-20 |
BR112014017969A8 true BR112014017969A8 (pt) | 2017-07-11 |
Family
ID=47630595
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014017969A BR112014017969A8 (pt) | 2012-01-23 | 2013-01-22 | Microesferas ou micropartículas bioerodíveis ou bio-degradáveis liberadas por tempo suspensas em uma formulação de droga injetável de formação de depósito |
Country Status (18)
Country | Link |
---|---|
US (3) | US20130189369A1 (pt) |
EP (1) | EP2806853B1 (pt) |
JP (1) | JP6282231B2 (pt) |
KR (5) | KR20140114892A (pt) |
CN (1) | CN104136006B (pt) |
AU (3) | AU2013212583A1 (pt) |
BR (1) | BR112014017969A8 (pt) |
CA (1) | CA2861348C (pt) |
DK (1) | DK2806853T3 (pt) |
ES (1) | ES2821526T3 (pt) |
HK (1) | HK1204765A1 (pt) |
HU (1) | HUE050904T2 (pt) |
IL (2) | IL233620A0 (pt) |
MX (1) | MX364864B (pt) |
NZ (1) | NZ627368A (pt) |
RU (1) | RU2672596C2 (pt) |
WO (1) | WO2013112434A1 (pt) |
ZA (1) | ZA201405091B (pt) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20150335704A1 (en) * | 2014-05-23 | 2015-11-26 | Imprimis Pharmaceuticals, Inc. | Pharmaceutical compositions comprising gels and methods for fabricating thereof |
US20170112936A1 (en) * | 2014-05-23 | 2017-04-27 | Imprimis Pharmaceuticals, Inc. | Pharmaceutical compositions comprising gels and methods for fabricating thereof |
CN104306330A (zh) * | 2014-09-24 | 2015-01-28 | 万特制药(海南)有限公司 | 一种盐酸美金刚缓释混悬液及其制备方法 |
WO2017053346A1 (en) | 2015-09-21 | 2017-03-30 | Teva Pharmaceuticals International Gmbh | Sustained release olanzapine formulations |
SG11201803663XA (en) | 2015-11-12 | 2018-05-30 | Graybug Vision Inc | Aggregating microparticles for therapy |
US10682340B2 (en) | 2016-06-30 | 2020-06-16 | Durect Corporation | Depot formulations |
JP7051721B2 (ja) | 2016-06-30 | 2022-04-11 | デュレクト コーポレーション | デポー製剤 |
CA3057438A1 (en) | 2017-03-20 | 2018-09-27 | Teva Pharmaceuticals International Gmbh | Sustained release olanzapine formulaitons |
CN111201040A (zh) | 2017-05-10 | 2020-05-26 | 灰色视觉公司 | 用于医学疗法的缓释微粒及其悬浮液 |
JP2020531571A (ja) * | 2017-07-11 | 2020-11-05 | サステインドナノシステムズエルエルシーSustained Nano Systems Llc | 超圧縮医薬製剤 |
CN107595765A (zh) * | 2017-09-22 | 2018-01-19 | 沈阳兴齐眼药股份有限公司 | 一种眼用缓释药物递送系统及其制备方法 |
GB2586975B (en) * | 2019-09-09 | 2024-03-06 | Roemex Ltd | Device and method for use with subsea pipelines |
US20240100012A1 (en) | 2021-01-18 | 2024-03-28 | Mark Hasleton | Pharmaceutical dosage form |
WO2022198167A1 (en) * | 2021-03-15 | 2022-09-22 | Oakwood Laboratories, Llc | Microsphere formulations comprising naltrexone and methods for making and using the same |
WO2023281406A1 (en) | 2021-07-06 | 2023-01-12 | Mark Hasleton | Treatment of serotonin reuptake inhibitor withdrawal syndrome |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5252318A (en) * | 1990-06-15 | 1993-10-12 | Allergan, Inc. | Reversible gelation compositions and methods of use |
DE69524398T2 (de) * | 1994-04-08 | 2002-07-18 | Atrix Lab Inc | Flüssige mittel zur wirkstoffabgabe |
AU739469B2 (en) * | 1996-12-20 | 2001-10-11 | Alza Corporation | Gel composition and methods |
US6589549B2 (en) * | 2000-04-27 | 2003-07-08 | Macromed, Incorporated | Bioactive agent delivering system comprised of microparticles within a biodegradable to improve release profiles |
GB0122318D0 (en) * | 2001-09-14 | 2001-11-07 | Novartis Ag | Organic compounds |
US20070196415A1 (en) * | 2002-11-14 | 2007-08-23 | Guohua Chen | Depot compositions with multiple drug release rate controls and uses thereof |
CN1314452C (zh) * | 2002-04-22 | 2007-05-09 | 沈阳药科大学 | 具有适宜相转变温度的眼用原位凝胶制剂 |
CN100453066C (zh) * | 2002-12-04 | 2009-01-21 | 参天制药株式会社 | 利用结膜下储存库的药物释放系统 |
US20090148527A1 (en) * | 2007-12-07 | 2009-06-11 | Robinson Michael R | Intraocular formulation |
US20060182781A1 (en) * | 2004-04-30 | 2006-08-17 | Allergan, Inc. | Methods for treating ocular conditions with cyclic lipid contraining microparticles |
US7893040B2 (en) * | 2005-07-22 | 2011-02-22 | Oculis Ehf | Cyclodextrin nanotechnology for ophthalmic drug delivery |
US20070202186A1 (en) * | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
ES2529746T3 (es) * | 2007-06-25 | 2015-02-25 | Otsuka Pharmaceutical Co., Ltd. | Microesferas con una estructura de núcleo/cáscara |
EP2482804A1 (en) * | 2009-10-01 | 2012-08-08 | Evonik Degussa Corporation | Microparticle compositions and methods for treating age-related macular degeneration |
CN101816627B (zh) * | 2010-04-16 | 2012-03-07 | 浙江大学 | 一种协同治疗型多物质缓释滴眼剂及制备方法 |
CN102100663B (zh) * | 2011-01-14 | 2013-04-17 | 华南理工大学 | 一种pH敏感型原位凝胶纳米缓释眼药水的制备方法 |
-
2013
- 2013-01-22 JP JP2014553507A patent/JP6282231B2/ja active Active
- 2013-01-22 MX MX2014008857A patent/MX364864B/es active IP Right Grant
- 2013-01-22 US US13/746,592 patent/US20130189369A1/en not_active Abandoned
- 2013-01-22 KR KR1020147023407A patent/KR20140114892A/ko active Application Filing
- 2013-01-22 RU RU2014134420A patent/RU2672596C2/ru active
- 2013-01-22 KR KR1020207033455A patent/KR20200133286A/ko not_active Application Discontinuation
- 2013-01-22 DK DK13702182.0T patent/DK2806853T3/da active
- 2013-01-22 HU HUE13702182A patent/HUE050904T2/hu unknown
- 2013-01-22 KR KR1020207016713A patent/KR102183727B1/ko active Application Filing
- 2013-01-22 WO PCT/US2013/022466 patent/WO2013112434A1/en active Application Filing
- 2013-01-22 CN CN201380010884.2A patent/CN104136006B/zh active Active
- 2013-01-22 NZ NZ627368A patent/NZ627368A/en unknown
- 2013-01-22 KR KR1020237021933A patent/KR20230104761A/ko not_active Application Discontinuation
- 2013-01-22 BR BR112014017969A patent/BR112014017969A8/pt not_active Application Discontinuation
- 2013-01-22 AU AU2013212583A patent/AU2013212583A1/en not_active Abandoned
- 2013-01-22 EP EP13702182.0A patent/EP2806853B1/en active Active
- 2013-01-22 KR KR1020227010024A patent/KR20220044379A/ko not_active Application Discontinuation
- 2013-01-22 ES ES13702182T patent/ES2821526T3/es active Active
- 2013-01-22 CA CA2861348A patent/CA2861348C/en active Active
-
2014
- 2014-07-11 ZA ZA2014/05091A patent/ZA201405091B/en unknown
- 2014-07-13 IL IL233620A patent/IL233620A0/en active IP Right Grant
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2015
- 2015-06-03 HK HK15105272.1A patent/HK1204765A1/xx unknown
-
2017
- 2017-11-09 AU AU2017258895A patent/AU2017258895B2/en active Active
-
2019
- 2019-03-26 IL IL265620A patent/IL265620B/en unknown
- 2019-07-10 AU AU2019204957A patent/AU2019204957A1/en not_active Abandoned
- 2019-12-19 US US16/720,892 patent/US20200297650A1/en not_active Abandoned
-
2022
- 2022-12-27 US US18/146,921 patent/US20230390212A1/en active Pending
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Legal Events
Date | Code | Title | Description |
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B12B | Appeal against refusal [chapter 12.2 patent gazette] |