BR112014029760A2 - dispositivos de distribuição de agente bioativo e métodos para fazer e usar os mesmos - Google Patents

dispositivos de distribuição de agente bioativo e métodos para fazer e usar os mesmos

Info

Publication number
BR112014029760A2
BR112014029760A2 BR112014029760A BR112014029760A BR112014029760A2 BR 112014029760 A2 BR112014029760 A2 BR 112014029760A2 BR 112014029760 A BR112014029760 A BR 112014029760A BR 112014029760 A BR112014029760 A BR 112014029760A BR 112014029760 A2 BR112014029760 A2 BR 112014029760A2
Authority
BR
Brazil
Prior art keywords
reservoirs
bioactive agent
making
methods
microdevice
Prior art date
Application number
BR112014029760A
Other languages
English (en)
Inventor
D Chirra Hariharasudhan
A Desai Tejal
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of BR112014029760A2 publication Critical patent/BR112014029760A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0097—Micromachined devices; Microelectromechanical systems [MEMS]; Devices obtained by lithographic treatment of silicon; Devices comprising chips
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03F—PHOTOMECHANICAL PRODUCTION OF TEXTURED OR PATTERNED SURFACES, e.g. FOR PRINTING, FOR PROCESSING OF SEMICONDUCTOR DEVICES; MATERIALS THEREFOR; ORIGINALS THEREFOR; APPARATUS SPECIALLY ADAPTED THEREFOR
    • G03F7/00—Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printing surfaces; Materials therefor, e.g. comprising photoresists; Apparatus specially adapted therefor
    • G03F7/0035—Multiple processes, e.g. applying a further resist layer on an already in a previously step, processed pattern or textured surface
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03F—PHOTOMECHANICAL PRODUCTION OF TEXTURED OR PATTERNED SURFACES, e.g. FOR PRINTING, FOR PROCESSING OF SEMICONDUCTOR DEVICES; MATERIALS THEREFOR; ORIGINALS THEREFOR; APPARATUS SPECIALLY ADAPTED THEREFOR
    • G03F7/00—Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printing surfaces; Materials therefor, e.g. comprising photoresists; Apparatus specially adapted therefor
    • G03F7/26—Processing photosensitive materials; Apparatus therefor
    • G03F7/40—Treatment after imagewise removal, e.g. baking

Landscapes

  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

abstract a method of preparing a substantially planar microdevice comprising a plurality of reservoirs is provided. in general, the method comprises forming a plurality of microdevices comprising a plurality of reservoirs from a planar layer of a biocompatible polymer. the method also comprises depositing one or more bioactive agents into the reservoirs. the microdevice is configured to attach to a target tissue and release the bioactive agent in close proximity to the tissue. tradução do resumo resumo "dispositivos de distribuição de agente bioativo e métodos para fazer e usar os mesmos" é fornecido um método para preparar um microdispositivo substancialmente planar compreendendo uma pluralidade de reservatórios. em geral, o método compreende formar uma pluralidade de microdispositivos compreendendo uma pluralidade de reservatórios de uma camada planar de um polímero biocompatível. o método compreende também depositar um ou mais agentes bioativos nos reservatórios. o microdispositivo é configurado para fixar a um tecido alvo e liberar o agente bioativo em estreita proximidade com o tecido.
BR112014029760A 2012-05-30 2013-05-24 dispositivos de distribuição de agente bioativo e métodos para fazer e usar os mesmos BR112014029760A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261653119P 2012-05-30 2012-05-30
PCT/US2013/042710 WO2013181107A1 (en) 2012-05-30 2013-05-24 Bioactive agent delivery devices and methods of making and using the same

Publications (1)

Publication Number Publication Date
BR112014029760A2 true BR112014029760A2 (pt) 2017-06-27

Family

ID=49673842

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014029760A BR112014029760A2 (pt) 2012-05-30 2013-05-24 dispositivos de distribuição de agente bioativo e métodos para fazer e usar os mesmos

Country Status (8)

Country Link
US (1) US9878137B2 (pt)
EP (1) EP2856259B1 (pt)
JP (1) JP6336442B2 (pt)
CN (1) CN104412160B (pt)
BR (1) BR112014029760A2 (pt)
CA (1) CA2875146C (pt)
IN (1) IN2014DN10765A (pt)
WO (1) WO2013181107A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220063293A (ko) 2011-11-18 2022-05-17 리제너론 파마슈티칼스 인코포레이티드 폴리머 단백질 미립자
US9463177B2 (en) 2012-09-10 2016-10-11 The Regents Of The University Of California Compounds and methods for modulating vascular injury
EP3082852B1 (en) 2013-12-16 2020-06-17 Massachusetts Institute of Technology Micromolded or 3-d printed pulsatile release vaccine formulations
CN106061292B (zh) 2013-12-16 2020-01-21 麻省理工学院 强化的微量营养素盐调配物
US10596125B2 (en) * 2014-12-15 2020-03-24 The Regents Of The University Of California Nanowire-coated microdevice and method of making and using the same
AU2016340072B2 (en) 2015-10-16 2021-10-28 Regeneron Pharmaceuticals, Inc. Stable protein compositions
US10429387B2 (en) * 2016-07-27 2019-10-01 Universiteit Tweate Simple and affordable method for immuophenotyping using a microfluidic chip sample preparation with image cytometry
EP3681486A1 (en) * 2017-09-13 2020-07-22 Massachusetts Institute of Technology Microdevices with complex geometries
JP7287032B2 (ja) * 2019-03-20 2023-06-06 株式会社リコー シート、シート積層体、医薬品、シートの製造方法、及びシート積層体の製造方法
CN113804667A (zh) * 2021-09-23 2021-12-17 上海交通大学 一种新型可膨胀生物样本的水凝胶及其应用

Family Cites Families (16)

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Publication number Priority date Publication date Assignee Title
US5410016A (en) 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
AU6104896A (en) * 1995-06-07 1996-12-30 Regents Of The University Of California, The Therapeutic microdevices and methods of making and using sam e
US5567271A (en) 1995-07-26 1996-10-22 Chartered Semiconductor Manufacturing Pte Ltd Oxygen reactive ion etch (RIE) plasma method for removing oxidized organic residues from semiconductor substrates
US5797898A (en) * 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
US6391216B1 (en) 1997-09-22 2002-05-21 National Research Institute For Metals Method for reactive ion etching and apparatus therefor
US6355270B1 (en) * 1999-01-11 2002-03-12 The Regents Of The University Of California Particles for oral delivery of peptides and proteins
US6770441B2 (en) 2000-02-10 2004-08-03 Illumina, Inc. Array compositions and methods of making same
US7351376B1 (en) * 2000-06-05 2008-04-01 California Institute Of Technology Integrated active flux microfluidic devices and methods
JP4657577B2 (ja) 2001-01-09 2011-03-23 マイクロチップス・インコーポレーテッド 眼への適用および他への適用のための可撓性マイクロチップデバイス
US20020115224A1 (en) * 2001-02-16 2002-08-22 Ulrich Rudel Method for the preparation of optical (bio)chemical sensor devices
AU2003251874A1 (en) * 2002-07-12 2004-02-02 Dirk R. Albrecht Three dimensional cell patterned bioploymer scaffolds and method of making the same
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US7887508B2 (en) 2006-03-14 2011-02-15 The University Of Southern California MEMS device and method for delivery of therapeutic agents
WO2008109886A1 (en) 2007-03-08 2008-09-12 The Regents Of The University Of California Topographically engineered structures and methods for using the same in regenerative medicine applications
EP2164425B1 (en) 2007-03-16 2015-10-28 The Regents of The University of California Nanostructure surface coated medical implants and methods of using the same
CA2758607C (en) * 2009-05-04 2018-05-15 Psivida Us, Inc. Porous silicon drug-eluting particles

Also Published As

Publication number Publication date
EP2856259A1 (en) 2015-04-08
EP2856259A4 (en) 2015-12-30
CN104412160A (zh) 2015-03-11
EP2856259B1 (en) 2018-12-26
CN104412160B (zh) 2019-09-20
US9878137B2 (en) 2018-01-30
JP2015519366A (ja) 2015-07-09
CA2875146A1 (en) 2013-12-05
IN2014DN10765A (pt) 2015-09-04
CA2875146C (en) 2022-03-22
US20150119807A1 (en) 2015-04-30
WO2013181107A1 (en) 2013-12-05
JP6336442B2 (ja) 2018-06-06

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements