DE60116764D1 - Vorrichtung zum verbessern der penetrierbarkeit eines punktierelementes in den intradermalen raum - Google Patents

Vorrichtung zum verbessern der penetrierbarkeit eines punktierelementes in den intradermalen raum

Info

Publication number
DE60116764D1
DE60116764D1 DE60116764T DE60116764T DE60116764D1 DE 60116764 D1 DE60116764 D1 DE 60116764D1 DE 60116764 T DE60116764 T DE 60116764T DE 60116764 T DE60116764 T DE 60116764T DE 60116764 D1 DE60116764 D1 DE 60116764D1
Authority
DE
Germany
Prior art keywords
skin
sampling
monitoring
substance
penetrationability
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60116764T
Other languages
English (en)
Other versions
DE60116764T2 (de
Inventor
J Palmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Application granted granted Critical
Publication of DE60116764D1 publication Critical patent/DE60116764D1/de
Publication of DE60116764T2 publication Critical patent/DE60116764T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/422Desensitising skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/425Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/46Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
DE60116764T 2000-06-06 2001-06-06 Vorrichtung zum verbessern der penetrierbarkeit eines punktierelementes in den intradermalen raum Expired - Lifetime DE60116764T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/588,767 US6537242B1 (en) 2000-06-06 2000-06-06 Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US588767 2000-06-06
PCT/US2001/018198 WO2001093931A1 (en) 2000-06-06 2001-06-06 Method and apparatus for enhancing penetration of a puncturing member into the intradermal space

Publications (2)

Publication Number Publication Date
DE60116764D1 true DE60116764D1 (de) 2006-04-06
DE60116764T2 DE60116764T2 (de) 2006-11-02

Family

ID=24355216

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60116764T Expired - Lifetime DE60116764T2 (de) 2000-06-06 2001-06-06 Vorrichtung zum verbessern der penetrierbarkeit eines punktierelementes in den intradermalen raum

Country Status (8)

Country Link
US (1) US6537242B1 (de)
EP (1) EP1289588B1 (de)
JP (1) JP4746818B2 (de)
AT (1) ATE315944T1 (de)
AU (1) AU2001275260A1 (de)
DE (1) DE60116764T2 (de)
ES (1) ES2254435T3 (de)
WO (1) WO2001093931A1 (de)

Families Citing this family (320)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6611707B1 (en) 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6641591B1 (en) 1999-08-26 2003-11-04 John H. Shadduck Instruments and techniques for controlled removal of epidermal layers
US20020095134A1 (en) * 1999-10-14 2002-07-18 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
US20020156453A1 (en) * 1999-10-14 2002-10-24 Pettis Ronald J. Method and device for reducing therapeutic dosage
US8465468B1 (en) 2000-06-29 2013-06-18 Becton, Dickinson And Company Intradermal delivery of substances
JP4312407B2 (ja) * 1999-12-10 2009-08-12 アルザ・コーポレーション 持続した経皮による薬物送達のための皮膚処理装置
US9717451B2 (en) * 2000-06-08 2017-08-01 Becton, Dickinson And Company Device for withdrawing or administering a substance and method of manufacturing a device
US20040175360A1 (en) * 2000-06-29 2004-09-09 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
GB0017999D0 (en) * 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
US6749575B2 (en) * 2001-08-20 2004-06-15 Alza Corporation Method for transdermal nucleic acid sampling
CA2425537C (en) * 2000-10-13 2009-09-08 Alza Corporation Microblade array impact applicator
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US7108681B2 (en) 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
IL155583A0 (en) * 2000-10-26 2003-11-23 Alza Corp Transdermal drug delivery devices having coated microprotrusions
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
ES2717656T3 (es) * 2000-11-30 2019-06-24 Valeritas Inc Dispositivo con microsonda amovible sustancialmente libre sobre el alojamiento
US9302903B2 (en) * 2000-12-14 2016-04-05 Georgia Tech Research Corporation Microneedle devices and production thereof
US6663820B2 (en) * 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
US6752817B2 (en) * 2001-03-26 2004-06-22 Bayer Corporation Split pressure ring for lancing device and method of operation
EP1381423A1 (de) * 2001-04-13 2004-01-21 Becton, Dickinson and Company Verfahren und vorrichtung zur intradermale abgabe von substanzen für systemischer absorption
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
WO2002085447A2 (en) * 2001-04-20 2002-10-31 Alza Corporation Microprojection array having a beneficial agent containing coating
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
AU2002348683A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
ES2357887T3 (es) 2001-06-12 2011-05-03 Pelikan Technologies Inc. Aparato para mejorar la tasa de éxito de obtención de sangre a partir de una punción capilar.
EP1404232B1 (de) 2001-06-12 2009-12-02 Pelikan Technologies Inc. Gerät und verfahren zur entnahme von blutproben
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
WO2002100460A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Electric lancet actuator
US7316700B2 (en) 2001-06-12 2008-01-08 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
US9795747B2 (en) * 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
BR0210628A (pt) * 2001-06-29 2004-08-10 Becton Dickinson Co Liberação intradérmica de vacinas e agentes terapêuticos genéticos via microcânula
CA2460063C (en) * 2001-09-12 2010-07-20 Becton, Dickinson And Company Microneedle-based pen device for drug delivery and method for using same
US20040087992A1 (en) * 2002-08-09 2004-05-06 Vladimir Gartstein Microstructures for delivering a composition cutaneously to skin using rotatable structures
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
WO2003066126A2 (en) * 2002-02-04 2003-08-14 Becton, Dickinson And Company Dermal access member
AU2003209645A1 (en) * 2002-03-04 2003-09-16 Nano Pass Technologies Ltd. Devices and methods for transporting fluid across a biological barrier
US7047070B2 (en) * 2002-04-02 2006-05-16 Becton, Dickinson And Company Valved intradermal delivery device and method of intradermally delivering a substance to a patient
US7115108B2 (en) * 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7708701B2 (en) 2002-04-19 2010-05-04 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US10973545B2 (en) 2002-05-31 2021-04-13 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
DE60328386D1 (de) 2002-05-31 2009-08-27 Vidacare Corp Vorrichtung und verfahren zum erreichen von knochenmark
US11337728B2 (en) 2002-05-31 2022-05-24 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
US7811260B2 (en) 2002-05-31 2010-10-12 Vidacare Corporation Apparatus and method to inject fluids into bone marrow and other target sites
US8668698B2 (en) 2002-05-31 2014-03-11 Vidacare Corporation Assembly for coupling powered driver with intraosseous device
US8641715B2 (en) 2002-05-31 2014-02-04 Vidacare Corporation Manual intraosseous device
WO2004020015A2 (en) * 2002-08-29 2004-03-11 Becton Dickinson And Company Microprotrusion arrays and methods for using same to deliver substances into tissue
CA2497086A1 (en) * 2002-08-30 2004-03-11 Becton, Dickinson And Company Method of controlling pharmacokinetics of immunomodulatory compounds
WO2004033021A1 (en) * 2002-10-07 2004-04-22 Biovalve Technologies, Inc. Microneedle array patch
ATE463202T1 (de) * 2002-12-30 2010-04-15 Hoffmann La Roche Kapillarrohr-spitzen-design zur unterstützung des blutflusses
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US7578954B2 (en) * 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
ES2347248T3 (es) 2003-05-30 2010-10-27 Pelikan Technologies Inc. Procedimiento y aparato para la inyeccion de fluido.
US9504477B2 (en) 2003-05-30 2016-11-29 Vidacare LLC Powered driver
US7850621B2 (en) 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
BRPI0411428A (pt) * 2003-06-13 2006-07-25 Becton Dickinson Co distribuição intradérmica de agentes biologicamente ativos
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
MXPA06000281A (es) * 2003-06-30 2006-07-03 Johnson & Johnson Formulaciones para microproyecciones revestidas que contienen contraiones no volatiles.
US20050180952A1 (en) * 2003-08-26 2005-08-18 Pettis Ronald J. Methods for intradermal delivery of therapeutics agents
JP4746545B2 (ja) 2003-08-28 2011-08-10 ベクトン・ディキンソン・アンド・カンパニー 皮内注射装置
WO2005033659A2 (en) 2003-09-29 2005-04-14 Pelikan Technologies, Inc. Method and apparatus for an improved sample capture device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
CN1897883A (zh) * 2003-10-28 2007-01-17 阿尔扎公司 通过涂覆的微喷射体释放治疗用肽和蛋白的聚合物缀合物
ATE539687T1 (de) * 2003-10-31 2012-01-15 Alza Corp Selbstbetätigter applikator für eine mikroprojektionsanordnung
KR20060113730A (ko) * 2003-12-18 2006-11-02 노보 노르디스크 에이/에스 피부 스트레칭 수단을 가진 노즐 장치
WO2005063115A1 (en) * 2003-12-22 2005-07-14 Hadvary Paul Dermallly affixed sensor device
JP2007516781A (ja) * 2003-12-29 2007-06-28 スリーエム イノベイティブ プロパティズ カンパニー 医療用具および該医療用具を含むキット
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
CN1636505B (zh) * 2004-01-09 2011-11-09 希森美康株式会社 提取器具、提取装置和血糖值测量装置
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
WO2005091922A2 (en) * 2004-03-03 2005-10-06 Becton, Dickinson And Company Methods and devices for improving delivery of a substance to skin
US7377903B2 (en) * 2004-03-05 2008-05-27 Roche Diagnostics Operations, Inc. Split tip expression device
US20050203575A1 (en) * 2004-03-15 2005-09-15 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Skin microactivation system and method
WO2005094526A2 (en) * 2004-03-24 2005-10-13 Corium International, Inc. Transdermal delivery device
US7201723B2 (en) * 2004-03-25 2007-04-10 Roche Diagnostics Operations, Inc. Pulsating expression cap
AU2005243727B2 (en) * 2004-04-12 2011-04-28 Allergan, Inc. Multi-site injection system
WO2005115360A2 (en) * 2004-05-11 2005-12-08 Becton, Dickinson And Company Formulations of anti-pain agents and methods of using the same
AU2005244734A1 (en) 2004-05-13 2005-12-01 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
EP1765194A4 (de) 2004-06-03 2010-09-29 Pelikan Technologies Inc Verfahren und gerät für eine flüssigkeitsentnahmenvorrichtung
ES2650188T3 (es) * 2004-06-10 2018-01-17 3M Innovative Properties Company Dispositivo y kit de aplicación de parches
US7076987B2 (en) * 2004-08-05 2006-07-18 Becton, Dickinson And Company Method of producing tapered or pointed cannula
US7641688B2 (en) 2004-09-16 2010-01-05 Evera Medical, Inc. Tissue augmentation device
US20060058892A1 (en) * 2004-09-16 2006-03-16 Lesh Michael D Valved tissue augmentation implant
US20080275569A1 (en) * 2004-09-16 2008-11-06 Evera Medical, Inc Tissue Augmentation Device
US7244270B2 (en) * 2004-09-16 2007-07-17 Evera Medical Systems and devices for soft tissue augmentation
US20060058891A1 (en) * 2004-09-16 2006-03-16 Lesh Michael D Transformable tissue bulking device
WO2006055795A1 (en) * 2004-11-18 2006-05-26 3M Innovative Properties Company Low-profile microneedle array applicator
WO2006055802A1 (en) * 2004-11-18 2006-05-26 3M Innovative Properties Company Microneedle array applicator and retainer
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
EP2388078B1 (de) 2004-11-18 2013-03-20 3M Innovative Properties Co. Verfahren zum Kontaktbeschichten einer Mikronadelanordnung
AU2012201016B2 (en) * 2004-11-18 2012-10-11 3M Innovative Properties Company Low-profile microneedle array applicator
EP1827564B1 (de) * 2004-11-18 2015-07-29 3M Innovative Properties Company Maskierungsverfahren zum beschichten einer mikronadelanordnung
US10207095B2 (en) * 2004-12-14 2019-02-19 C. R. Bard, Inc. Fast clear port
US7697967B2 (en) 2005-12-28 2010-04-13 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US10226207B2 (en) * 2004-12-29 2019-03-12 Abbott Diabetes Care Inc. Sensor inserter having introducer
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
WO2006108185A1 (en) 2005-04-07 2006-10-12 3M Innovative Properties Company System and method for tool feedback sensing
WO2007002523A2 (en) * 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
CA2613111C (en) * 2005-06-27 2015-05-26 3M Innovative Properties Company Microneedle array applicator device and method of array application
US20070038148A1 (en) * 2005-08-11 2007-02-15 Joel Mechelke Sampling module for extracting interstitial fluid
US7967763B2 (en) * 2005-09-07 2011-06-28 Cabochon Aesthetics, Inc. Method for treating subcutaneous tissues
US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US8518069B2 (en) 2005-09-07 2013-08-27 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9358033B2 (en) 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
US10548659B2 (en) 2006-01-17 2020-02-04 Ulthera, Inc. High pressure pre-burst for improved fluid delivery
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
JP2007097980A (ja) * 2005-10-07 2007-04-19 Univ Kansai 穿刺デバイスおよびその製造方法
EP1785090A1 (de) * 2005-11-10 2007-05-16 F.Hoffmann-La Roche Ag Stechelement, Stechsystem und Verfahren zur Hautdetektion
US7842008B2 (en) * 2005-11-21 2010-11-30 Becton, Dickinson And Company Intradermal delivery device
US20080200864A1 (en) * 2005-12-02 2008-08-21 Cabochon Aesthetics, Inc. Devices and methods for selectively lysing cells
US20080195036A1 (en) * 2005-12-02 2008-08-14 Cabochon Aesthetics, Inc. Devices and methods for selectively lysing cells
US7885793B2 (en) 2007-05-22 2011-02-08 International Business Machines Corporation Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution
US9248317B2 (en) 2005-12-02 2016-02-02 Ulthera, Inc. Devices and methods for selectively lysing cells
WO2007066341A2 (en) * 2005-12-08 2007-06-14 Nanopass Technologies Ltd. Microneedle adapter for dosed drug delivery devices
CN101340940B (zh) 2005-12-20 2012-07-18 诺沃-诺迪斯克有限公司 用于药物射流喷射单元的皮肤保持装置
US11298058B2 (en) 2005-12-28 2022-04-12 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US8048089B2 (en) 2005-12-30 2011-11-01 Edge Systems Corporation Apparatus and methods for treating the skin
US20100168501A1 (en) * 2006-10-02 2010-07-01 Daniel Rogers Burnett Method and apparatus for magnetic induction therapy
WO2011053607A1 (en) 2009-10-26 2011-05-05 Emkinetics, Inc. Method and apparatus for electromagnetic stimulation of nerve, muscle, and body tissues
US9339641B2 (en) 2006-01-17 2016-05-17 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US9610459B2 (en) * 2009-07-24 2017-04-04 Emkinetics, Inc. Cooling systems and methods for conductive coils
JP4944803B2 (ja) * 2006-02-09 2012-06-06 パナソニック株式会社 血液検査装置
US9566088B2 (en) 2006-03-29 2017-02-14 Edge Systems Llc Devices, systems and methods for treating the skin
US10172644B2 (en) 2006-03-29 2019-01-08 Edge Systems Llc Devices, systems and methods for treating the skin
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
US20070276425A1 (en) * 2006-05-29 2007-11-29 Stanley Kim Painless Blood Sampling Lancet with Bundled Multiple Thin Needles
WO2007140381A2 (en) * 2006-05-29 2007-12-06 Stanley Kim Multiple needle system
JP2008022988A (ja) * 2006-07-19 2008-02-07 Ritsumeikan 採血装置
CN104814768B (zh) 2006-09-12 2018-04-13 维达保健有限责任公司 医疗程序托盘及相关方法
US8944069B2 (en) 2006-09-12 2015-02-03 Vidacare Corporation Assemblies for coupling intraosseous (IO) devices to powered drivers
US9005102B2 (en) 2006-10-02 2015-04-14 Emkinetics, Inc. Method and apparatus for electrical stimulation therapy
WO2008042902A2 (en) * 2006-10-02 2008-04-10 Emkinetics, Inc. Method and apparatus for magnetic induction therapy
US11224742B2 (en) 2006-10-02 2022-01-18 Emkinetics, Inc. Methods and devices for performing electrical stimulation to treat various conditions
US10786669B2 (en) 2006-10-02 2020-09-29 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
KR20080051342A (ko) * 2006-12-05 2008-06-11 연세대학교 산학협력단 마이크로니들 기기 및 이의 응용방법
JP2008154849A (ja) * 2006-12-25 2008-07-10 Ritsumeikan 注入装置
EP2121111B1 (de) * 2007-01-22 2018-03-14 Corium International, Inc. Applikator für mikronadelanordnung
JP4978245B2 (ja) * 2007-03-08 2012-07-18 凸版印刷株式会社 針状体、針状体製造方法および薬物輸送デバイス
EP2136863A2 (de) * 2007-03-19 2009-12-30 Insuline Medical Ltd. Vorrichtung zur abgabe von arzneimitteln und relevante verbindungen
KR20090128499A (ko) * 2007-03-19 2009-12-15 인슐린 메디컬 엘티디 약물 전달 장치
EP2131723B1 (de) * 2007-03-19 2013-07-24 Insuline Medical Ltd. Vorrichtung zur messung von substanzen
US8622991B2 (en) * 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
US9220837B2 (en) * 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
EP2146689B1 (de) 2007-04-16 2020-08-12 Corium, Inc. Einen wirkstoff enthaltende lösungsmittel-gegossene mikronadelanordnungen
US8911749B2 (en) * 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
JP5044334B2 (ja) * 2007-09-06 2012-10-10 株式会社ニコン 採液収容装置
JP5222512B2 (ja) * 2007-09-19 2013-06-26 凸版印刷株式会社 マイクロニードルチップ
US20090093723A1 (en) * 2007-10-05 2009-04-09 Cabochon Aesthetics, Inc. Ultrasound device including dispenser
US8439940B2 (en) 2010-12-22 2013-05-14 Cabochon Aesthetics, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
EP2209424A1 (de) * 2007-10-09 2010-07-28 Cabochon Aesthetics, Inc. Ultraschallgerät mit behandlungslinse
US20090093738A1 (en) * 2007-10-09 2009-04-09 Cabochon Aesthetics, Inc. Device and method for monitoring a treatment area
JP5178132B2 (ja) * 2007-10-11 2013-04-10 キヤノン株式会社 画像処理システム並びに画像処理方法
US20090247984A1 (en) * 2007-10-24 2009-10-01 Masimo Laboratories, Inc. Use of microneedles for small molecule metabolite reporter delivery
EP2231229A1 (de) * 2007-12-18 2010-09-29 Insuline Medical Ltd. Wirkstofffreisetzungsvorrichtung mit sensor für geschlossenen kreislauf
EP2231257A4 (de) 2007-12-24 2013-11-06 Univ Queensland Beschichtungsverfahren
KR101836310B1 (ko) 2008-01-04 2018-03-08 엣지 시스템즈 엘엘씨 피부 처리 장치 및 방법
WO2009097451A1 (en) 2008-01-29 2009-08-06 Edge Systems Corporation Apparatus and method for treating the skin
US20090198329A1 (en) 2008-02-01 2009-08-06 Kesten Randy J Breast implant with internal flow dampening
US20090198331A1 (en) * 2008-02-01 2009-08-06 Kesten Randy J Implantable prosthesis with open cell flow regulation
US9386944B2 (en) 2008-04-11 2016-07-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte detecting device
WO2009130926A1 (ja) * 2008-04-22 2009-10-29 南部化成株式会社 経皮投薬方法、ニードル形成体及び経皮投薬装置
WO2009136479A1 (ja) * 2008-05-09 2009-11-12 パナソニック株式会社 皮膚切開器具およびそれによって皮膚を切開する方法
WO2009139134A1 (ja) * 2008-05-13 2009-11-19 パナソニック株式会社 皮膚切開器具およびそれによって皮膚を切開する方法
US8882753B2 (en) * 2008-07-14 2014-11-11 Syneron Medical Ltd Devices and methods for percutaneous energy delivery
US20100106063A1 (en) * 2008-10-29 2010-04-29 Cabochon Aesthetics, Inc. Ultrasound Enhancing Target for Treating Subcutaneous Tissue
BRPI0916125A2 (pt) 2008-11-07 2015-11-03 Insuline Medical Ltd "dispositivo de tratamento"
JP5713913B2 (ja) * 2008-11-07 2015-05-07 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company 薬剤の注射を容易にするシリンジ筐体
WO2010077278A1 (en) 2008-12-09 2010-07-08 Becton, Dickinson And Company Dual-chambered drug delivery device for high pressure injections
ES2784740T3 (es) 2008-12-09 2020-09-30 Becton Dickinson Co Sistema de suministro de medicación con multiplicador de fuerza de palanca y engranaje para sistema de inyección a alta presión
JP5739346B2 (ja) 2008-12-09 2015-06-24 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company 高圧注射用薬物送達器材のための多行程送達ポンピング機構
JP5662337B2 (ja) 2008-12-09 2015-01-28 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company 高圧の注射のための開閉バルブの薬物送達システム
KR101033513B1 (ko) * 2009-01-20 2011-05-09 (주)마이티시스템 미세바늘을 이용한 유용성분 피부전달용 용기
WO2011056182A1 (en) * 2009-01-27 2011-05-12 Becton, Dickinson And Company Infusion set with anesthetic compound
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US8167280B2 (en) * 2009-03-23 2012-05-01 Cabochon Aesthetics, Inc. Bubble generator having disposable bubble cartridges
US20100256596A1 (en) * 2009-04-07 2010-10-07 Cabochon Aesthetics, Inc. Fiber growth promoting implants for reducing the appearance of cellulite
EP2429627B1 (de) * 2009-04-24 2017-06-14 Corium International, Inc. Verfahren zur herstellung von mikroprojektionsarrays
WO2011006009A1 (en) 2009-07-08 2011-01-13 Edge Systems Corporation Devices, systems and methods for treating the skin using time-release substances
US9358064B2 (en) 2009-08-07 2016-06-07 Ulthera, Inc. Handpiece and methods for performing subcutaneous surgery
JP5663792B2 (ja) * 2009-08-07 2015-02-04 株式会社 メドレックス 剣山型マイクロニードルのアプリケータデバイス
US11096708B2 (en) 2009-08-07 2021-08-24 Ulthera, Inc. Devices and methods for performing subcutaneous surgery
US8409147B2 (en) * 2009-08-22 2013-04-02 Joseph Wayne Kraft Rapid local anesthesia linear injection device
US8088108B2 (en) * 2009-08-22 2012-01-03 Joseph Wayne Kraft Rapid local anesthesia injection cone
JP2011045565A (ja) * 2009-08-27 2011-03-10 Nanbu Plastics Co Ltd 薬液注入装置
EP2482724A2 (de) 2009-09-30 2012-08-08 Dexcom, Inc. Transkutaner analytsensor
DE102009046581A1 (de) * 2009-11-10 2011-05-12 Robert Bosch Gmbh Herstellungsverfahren für eine poröse Mikronadelanordnung und entsprechende poröse Mikronadelanordnung und entsprechender Substratverbund
RU2539991C2 (ru) * 2009-12-16 2015-01-27 Кронтек Фарма Аб Впрыскивающие игла и устройство
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
ES2719595T3 (es) 2010-05-04 2019-07-11 Corium Int Inc Método y dispositivo para la administración transdérmica de la hormona paratiroidea usando una matriz de microproyección
WO2011140240A2 (en) 2010-05-04 2011-11-10 Corium International, Inc. Applicators for microneedles
US8588884B2 (en) 2010-05-28 2013-11-19 Emkinetics, Inc. Microneedle electrode
US9943673B2 (en) 2010-07-14 2018-04-17 Vaxxas Pty Limited Patch applying apparatus
JP5770055B2 (ja) * 2010-09-29 2015-08-26 富士フイルム株式会社 針状アレイ経皮吸収シートの製造方法
US9017289B2 (en) 2010-11-03 2015-04-28 Covidien Lp Transdermal fluid delivery device
US20130296791A1 (en) * 2011-01-18 2013-11-07 Michael Segev Medication delivery assembly
CA2831613A1 (en) 2011-03-31 2012-10-04 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
JP4923156B1 (ja) * 2011-05-24 2012-04-25 エム・エフ・ヴィ株式会社 塗布用具
WO2012166965A2 (en) * 2011-05-31 2012-12-06 Microlin, Llc An apparatus and method for dermal delivery
GB201109620D0 (en) * 2011-06-09 2011-07-20 Ardehali Massoud H Injection apparatus
US20140207101A1 (en) * 2011-06-09 2014-07-24 3M Innovative Properties Company Microstructure device with removable microstructure patch
US20120316499A1 (en) * 2011-06-10 2012-12-13 Erich George Brehm Fluid Delivery System
WO2012172424A1 (en) 2011-06-15 2012-12-20 Crontech Pharma Ab Injection needle and device
CN107684451B (zh) 2011-07-11 2021-07-06 泰利弗雷克斯医药工具有限公司 胸骨定位器以及相关系统和方法
WO2013046868A1 (ja) * 2011-09-29 2013-04-04 テルモ株式会社 シリンジ
EP2765927B1 (de) 2011-10-12 2021-02-24 Vaxxas Pty Limited Abgabegerät
JP6073016B2 (ja) * 2011-11-04 2017-02-01 ニプロ株式会社 注射針の製造方法
EP2589401A1 (de) * 2011-11-04 2013-05-08 Fiderm S.r.l. (Ricerca e Technogie in Scienze Dermatologiche) Vorrichtung zur Steuerung der Tiefe und zur Reduzierung des Schmerzes von Injektionen
ES2904536T3 (es) * 2011-11-07 2022-04-05 Lilly Co Eli Dispositivos de inyección con mejoras ergonómicas
EP2791160B1 (de) 2011-12-16 2022-03-02 ModernaTX, Inc. Modifizierte mrna zusammensetzungen
WO2013151766A1 (en) * 2012-04-02 2013-10-10 Medtronic, Inc. Therapy for kidney disease and/or heart failure by intradermal infusion
EP3563772B1 (de) * 2012-08-14 2022-01-12 The General Hospital Corporation Vorrichtung zur gewebeableitung
CN103673821A (zh) * 2012-09-03 2014-03-26 致茂电子(苏州)有限公司 探针压缩行程量测方法与相关的电路测试系统
WO2014058746A1 (en) * 2012-10-10 2014-04-17 3M Innovative Properties Company Force-controlled applicator for applying a microneedle device to skin
US20140107450A1 (en) 2012-10-12 2014-04-17 Dexcom, Inc. Sensors for continuous analyte monitoring, and related methods
US20140213866A1 (en) 2012-10-12 2014-07-31 Dexcom, Inc. Sensors for continuous analyte monitoring, and related methods
AU2013331015B2 (en) * 2012-10-19 2017-11-16 Amgen, Inc. Improved autoinjector
PT2922554T (pt) 2012-11-26 2022-06-28 Modernatx Inc Arn modificado nas porções terminais
US11052231B2 (en) 2012-12-21 2021-07-06 Corium, Inc. Microarray for delivery of therapeutic agent and methods of use
EP3932463A1 (de) * 2013-01-08 2022-01-05 Kindeva Drug Delivery L.P. Vorrichtung zum aufbringen einer mikronadelvorrichtung auf die haut
JP2016504050A (ja) 2013-01-17 2016-02-12 モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. 細胞表現型の改変のためのシグナルセンサーポリヌクレオチド
US9717893B2 (en) 2013-02-13 2017-08-01 Hisamitsu Pharmaceutical Co., Ltd. Microneedle array
US10543127B2 (en) 2013-02-20 2020-01-28 Cytrellis Biosystems, Inc. Methods and devices for skin tightening
CN109621083B (zh) * 2013-02-28 2022-03-22 索伦托治疗有限公司 药物递送装置
RU2674083C2 (ru) 2013-03-12 2018-12-04 Кориум Интернэшнл, Инк. Аппликаторы с микровыступами
WO2014159813A1 (en) 2013-03-13 2014-10-02 Moderna Therapeutics, Inc. Long-lived polynucleotide molecules
EP2968116A1 (de) 2013-03-15 2016-01-20 Corium International, Inc. Mikroarray mit polymerfreien mikrostrukturen, verfahren zur herstellung und verfahren zur verwendung
US10238812B2 (en) 2013-03-15 2019-03-26 Edge Systems Llc Skin treatment systems and methods using needles
WO2014150285A2 (en) 2013-03-15 2014-09-25 Corium International, Inc. Multiple impact microprojection applicators and methods of use
AU2014233695A1 (en) 2013-03-15 2015-10-01 Corium International, Inc. Microarray for delivery of therapeutic agent and methods of use
ES2761580T3 (es) 2013-03-15 2020-05-20 Corium Inc Micromatrices para suministro de agente terapéutico, métodos de uso y métodos de fabricación
EP3437575B1 (de) 2013-03-15 2021-04-21 Edge Systems LLC Vorrichtungen und systeme zur hautbehandlung
ES2662110T3 (es) 2013-04-15 2018-04-05 Becton, Dickinson And Company Dispositivo de transferencia de muestras de fluidos biológicos y sistema de separación y de análisis de fluidos biológicos
GB201307262D0 (en) 2013-04-23 2013-05-29 Chowdhury Dewan F H Device for containment and release of drug formulation
US9474849B2 (en) * 2013-06-07 2016-10-25 John Richard Parker Apparatus and method for reducing incidence of tick borne infections
US20150182703A1 (en) * 2013-12-02 2015-07-02 Biltmore Technologies, Inc. Nanofluidic delivery system
DE102013021058B4 (de) 2013-12-18 2017-10-12 Gerresheimer Regensburg Gmbh Vorrichtung zur Applizierung eines Nadelarrays auf biologischem Gewebe
JP6167048B2 (ja) * 2014-02-14 2017-07-19 株式会社ダイセル 無針注射器
US20150289788A1 (en) 2014-04-10 2015-10-15 Dexcom, Inc. Sensors for continuous analyte monitoring, and related methods
JP5896093B1 (ja) * 2014-04-14 2016-03-30 凸版印刷株式会社 注入器具
US10004845B2 (en) 2014-04-18 2018-06-26 Becton, Dickinson And Company Split piston metering pump
US9416775B2 (en) 2014-07-02 2016-08-16 Becton, Dickinson And Company Internal cam metering pump
EP2982302B1 (de) * 2014-08-05 2018-05-23 Roche Diabetes Care GmbH Medizinischer Applikator
WO2016036866A1 (en) 2014-09-04 2016-03-10 Corium International, Inc. Microstructure array, methods of making, and methods of use
WO2016077759A1 (en) 2014-11-14 2016-05-19 Cytrellis Biosystems, Inc. Devices and methods for ablation of the skin
EP3795204B1 (de) 2014-12-23 2023-10-25 HydraFacial LLC Vorrichtung zur behandlung der haut mittels eines rollballens
US10179229B2 (en) 2014-12-23 2019-01-15 Edge Systems Llc Devices and methods for treating the skin using a porous member
EP3253440B1 (de) 2015-02-02 2022-12-21 Vaxxas Pty Limited Mikroprojektionsarrayapplikator
JPWO2016129184A1 (ja) * 2015-02-13 2017-04-27 株式会社 メドレックス マイクロニードルの穿刺装置及びマイクロニードルパッチの貼付装置
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
WO2017007939A1 (en) 2015-07-08 2017-01-12 Edge Systems Llc Devices, systems and methods for promoting hair growth
US11103259B2 (en) 2015-09-18 2021-08-31 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
KR101711417B1 (ko) * 2015-10-14 2017-03-14 인하대학교 산학협력단 의료용 미소스테이플 삽입장치
US20170165434A1 (en) * 2015-12-10 2017-06-15 Xiamen Brana Design Co., Ltd. Multi-needle needle assembly
CN112089961B (zh) * 2015-12-21 2022-08-09 美德阿利克斯株式会社 微针贴片施用器及其壳体
US10500351B2 (en) 2016-02-12 2019-12-10 Shawn Michael Michels Aid for subcutaneous tissue injection and process of effecting the injection with the aid
US10220195B2 (en) * 2016-06-08 2019-03-05 Eclipse Medcorp, Llc Radio frequency needling device for use with disposable needle cartridges
JP6670207B2 (ja) * 2016-08-26 2020-03-18 日本発條株式会社 穿刺デバイス
WO2018057630A1 (en) 2016-09-21 2018-03-29 Cytrellis Biosystems, Inc. Devices and methods for cosmetic skin resurfacing
CN110300608B (zh) 2016-12-16 2021-10-19 索伦托治疗有限公司 具有抽气机构的流体递送装置及其使用方法
JP7008709B2 (ja) 2016-12-16 2022-01-25 ソレント・セラピューティクス・インコーポレイテッド 制御アセンブリを有する流体送達装置及びその使用方法
ES2943307T3 (es) 2016-12-16 2023-06-12 Sorrento Therapeutics Inc Aparato de suministro de fluido que incluye un conjunto de microagujas adecuado para tratar una migraña o dolor de cabeza en brotes
ES2898083T3 (es) 2016-12-16 2022-03-03 Sorrento Therapeutics Inc Aparato de suministro de líquidos y procedimiento de montaje
WO2018111616A1 (en) 2016-12-16 2018-06-21 Kimberly-Clark Worldwide, Inc. Application device for a fluid delivery apparatus and method of use
AU2017378020B2 (en) * 2016-12-16 2023-06-29 Sorrento Therapeutics, Inc. Attachment band for a fluid delivery apparatus and method of use
US10751484B2 (en) * 2017-01-26 2020-08-25 Allergan Industrie, Sas Needle array device
DK3606760T3 (da) 2017-03-31 2023-11-06 Vaxxas Pty Ltd Indretning og fremgangsmåde til belægning af overflader
US11039823B2 (en) 2017-05-03 2021-06-22 Z Surgical Llc Minimal-access percutaneous and self-retracting surgical system
WO2018227246A1 (en) 2017-06-13 2018-12-20 Vaxxas Pty Limited Quality control of substrate coatings
EP3661587A4 (de) 2017-08-04 2021-06-09 Vaxxas Pty Limited Kompakter hoher mechanischer energiespeicher und aktuator mit geringer auslösekraft für die abgabe von mikroprojektions-array-patches (map)
CA3089513A1 (en) * 2018-01-24 2019-08-01 Cosmed Pharmaceutical Co., Ltd. Tight-binding device for micro-needle
CN111836662A (zh) * 2018-03-13 2020-10-27 美德阿利克斯株式会社 粘合构件和微针贴剂
JP2019170870A (ja) * 2018-03-29 2019-10-10 凸版印刷株式会社 マイクロニードル
JP1632957S (de) 2018-10-30 2019-06-03
US11369409B2 (en) * 2019-10-03 2022-06-28 Medline Industries, Lp System and method for fluid ingress control for a skin grafting system
KR20220097412A (ko) * 2019-10-24 2022-07-07 자닌 홉킨스 어플리케이터 장치 및 사용 방법
WO2021121589A1 (en) * 2019-12-18 2021-06-24 Uprax Microsolutions B.V. Applicators and methods for applying a microneedle patch to a skin of a subject, and microneedle patches
JPWO2021177317A1 (de) * 2020-03-02 2021-09-10
US20210353878A1 (en) * 2020-05-14 2021-11-18 Jonathan Robin Fugo Hypodermic device with an array of hypodermic needles
EP4161611A1 (de) * 2020-06-04 2023-04-12 SHL Medical AG Komponente einer medikamentenabgabevorrichtung oder zusatzmodul für eine medikamentenabgabevorrichtung
EP4223353A1 (de) 2020-09-30 2023-08-09 Shiseido Company, Ltd. Teil mit nadelförmigen vorsprüngen
USD1016615S1 (en) 2021-09-10 2024-03-05 Hydrafacial Llc Container for a skin treatment device
US20230277759A1 (en) * 2022-03-03 2023-09-07 Deka Products Limited Partnership Systems, Methods, and Apparatuses for Medical Agent Administration
WO2023205341A1 (en) * 2022-04-22 2023-10-26 The Board Of Trustees Of The Leland Stanford Junior University Compliant polymeric structures having polymeric microneedles and methods for making and using same

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1216813A (en) 1969-02-21 1970-12-23 Shozo Narusawa Transcutaneous injection device
CH582884A5 (de) * 1973-12-10 1976-12-15 Hoffmann La Roche
CA1272423A (en) * 1986-02-25 1990-08-07 Peter C. Lord Soft cannula subcutaneous injection set and method of making same
US4695273A (en) 1986-04-08 1987-09-22 I-Flow Corporation Multiple needle holder and subcutaneous multiple channel infusion port
FR2612401A1 (fr) 1987-03-16 1988-09-23 Denance Raymond Embout stabilisateur pour aiguille hypodermique comportant un moyen faisant office de bequille pour reguler la penetration en fonction de l'angle d'attaque de l'aiguille dans la peau
EP0429842B1 (de) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten
JPH0626570B2 (ja) * 1991-01-31 1994-04-13 参天製薬株式会社 二層式注射器の注射筒
JP3590805B2 (ja) * 1993-11-10 2004-11-17 株式会社ニコン 採血装置
AU5740496A (en) 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
SE9502285D0 (sv) 1995-06-22 1995-06-22 Pharmacia Ab Improvements related to injections
JP2718408B2 (ja) * 1995-09-20 1998-02-25 日本電気株式会社 浸出液吸引装置
ES2297858T3 (es) * 1996-05-17 2008-05-01 Roche Diagnostics Operations, Inc. Elemento desechable que se utiliza en un dispositivo de muestreo de liquido corporal.
DE69719761T2 (de) 1996-06-18 2003-12-18 Alza Corp Vorrichtung zur verbesserung der transdermalen verabreichung von medikamenten oder der abnahme von körperflüssigkeiten
IT1298087B1 (it) 1998-01-08 1999-12-20 Fiderm S R L Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
JP3382853B2 (ja) * 1998-04-09 2003-03-04 松下電器産業株式会社 体液検査装置
CA2229522A1 (en) 1998-04-15 1999-10-15 Thomas Randall Inkpen Needle aid
WO1999064580A1 (en) * 1998-06-10 1999-12-16 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
EP1187653B1 (de) 1999-06-04 2010-03-31 Georgia Tech Research Corporation Vorrichtungen zur vergrösserten penetration von mikronadeln in biologischen hautschichten
DE60024312T2 (de) 1999-12-10 2006-08-17 Alza Corp., Mountain View Transdermale Wirkstoffabgabe von makromolekularen Wirkstoffen und Vorrichtung hierfür

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JP4746818B2 (ja) 2011-08-10
DE60116764T2 (de) 2006-11-02
EP1289588A1 (de) 2003-03-12
ES2254435T3 (es) 2006-06-16
EP1289588B1 (de) 2006-01-18
JP2003534881A (ja) 2003-11-25
ATE315944T1 (de) 2006-02-15
AU2001275260A1 (en) 2001-12-17
US6537242B1 (en) 2003-03-25
WO2001093931A1 (en) 2001-12-13

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