AU2001275260A1 - Method and apparatus for enhancing penetration of a puncturing member into the intradermal space - Google Patents

Method and apparatus for enhancing penetration of a puncturing member into the intradermal space

Info

Publication number
AU2001275260A1
AU2001275260A1 AU2001275260A AU7526001A AU2001275260A1 AU 2001275260 A1 AU2001275260 A1 AU 2001275260A1 AU 2001275260 A AU2001275260 A AU 2001275260A AU 7526001 A AU7526001 A AU 7526001A AU 2001275260 A1 AU2001275260 A1 AU 2001275260A1
Authority
AU
Australia
Prior art keywords
skin
sampling
monitoring
substance
stretching
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001275260A
Inventor
Phyllis J. Palmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of AU2001275260A1 publication Critical patent/AU2001275260A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/422—Desensitising skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/425—Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Arc Welding In General (AREA)
  • Telephone Function (AREA)
  • Image-Pickup Tubes, Image-Amplification Tubes, And Storage Tubes (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

A device for monitoring, sampling or delivering a substance to the skin of a patient includes a medical device and a stretching device for stretching the skin to enhance the contact by the medical device. The medical device generally includes at least a skin penetrating member, such as a cannula. The cannula can be a single needle or an array of microneedles. The method for monitoring, sampling or delivering a substance positions the device on the skin and presses downwardly on the device causing the stretching device to stretch the skin in a target area of the skin penetrating member to enable uniform penetration of the skin. The uniform penetration provides for a more uniform monitoring, sampling or delivery of the substance to the patient.
AU2001275260A 2000-06-06 2001-06-06 Method and apparatus for enhancing penetration of a puncturing member into the intradermal space Abandoned AU2001275260A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/588,767 US6537242B1 (en) 2000-06-06 2000-06-06 Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US09588767 2000-06-06
PCT/US2001/018198 WO2001093931A1 (en) 2000-06-06 2001-06-06 Method and apparatus for enhancing penetration of a puncturing member into the intradermal space

Publications (1)

Publication Number Publication Date
AU2001275260A1 true AU2001275260A1 (en) 2001-12-17

Family

ID=24355216

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001275260A Abandoned AU2001275260A1 (en) 2000-06-06 2001-06-06 Method and apparatus for enhancing penetration of a puncturing member into the intradermal space

Country Status (8)

Country Link
US (1) US6537242B1 (en)
EP (1) EP1289588B1 (en)
JP (1) JP4746818B2 (en)
AT (1) ATE315944T1 (en)
AU (1) AU2001275260A1 (en)
DE (1) DE60116764T2 (en)
ES (1) ES2254435T3 (en)
WO (1) WO2001093931A1 (en)

Families Citing this family (322)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US6611707B1 (en) 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6641591B1 (en) 1999-08-26 2003-11-04 John H. Shadduck Instruments and techniques for controlled removal of epidermal layers
US8465468B1 (en) 2000-06-29 2013-06-18 Becton, Dickinson And Company Intradermal delivery of substances
US20020095134A1 (en) * 1999-10-14 2002-07-18 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
US20020156453A1 (en) * 1999-10-14 2002-10-24 Pettis Ronald J. Method and device for reducing therapeutic dosage
HU225467B1 (en) * 1999-12-10 2006-12-28 Alza Corp Skin treatment apparatus for sustained transdermal drug delivery
US9717451B2 (en) * 2000-06-08 2017-08-01 Becton, Dickinson And Company Device for withdrawing or administering a substance and method of manufacturing a device
US20040175360A1 (en) * 2000-06-29 2004-09-09 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
GB0017999D0 (en) * 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
US6749575B2 (en) * 2001-08-20 2004-06-15 Alza Corporation Method for transdermal nucleic acid sampling
ES2243564T3 (en) * 2000-10-13 2005-12-01 Alza Corporation MICROLAMAS NETWORK APPLICATOR THAT PRODUCES AN IMPACT.
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
US7108681B2 (en) 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
RU2282468C2 (en) * 2000-10-26 2006-08-27 Алза Корпорейшн Device having coated micro projections for carrying out transdermal drug delivery
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
EP1412017B1 (en) * 2000-11-30 2016-04-13 Valeritas, Inc. Fluid delivery and measurement systems and methods
WO2002064193A2 (en) * 2000-12-14 2002-08-22 Georgia Tech Research Corporation Microneedle devices and production thereof
US6663820B2 (en) * 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
US6752817B2 (en) * 2001-03-26 2004-06-22 Bayer Corporation Split pressure ring for lancing device and method of operation
JP2004525713A (en) * 2001-04-13 2004-08-26 ベクトン・ディキンソン・アンド・カンパニー Methods and devices for administering substances into the intradermal layer of the skin for systemic absorption
MXPA03009603A (en) * 2001-04-20 2004-12-06 Johnson & Johnson Microprojection array having a beneficial agent containing coating.
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
ES2357887T3 (en) 2001-06-12 2011-05-03 Pelikan Technologies Inc. APPARATUS FOR IMPROVING THE BLOOD OBTAINING SUCCESS RATE FROM A CAPILLARY PUNCTURE.
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
AU2002348683A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US7344507B2 (en) 2002-04-19 2008-03-18 Pelikan Technologies, Inc. Method and apparatus for lancet actuation
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
WO2002100460A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Electric lancet actuator
US7316700B2 (en) 2001-06-12 2008-01-08 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
ATE450209T1 (en) 2001-06-12 2009-12-15 Pelikan Technologies Inc APPARATUS AND METHOD FOR COLLECTING BLOOD SAMPLES
CN1253220C (en) * 2001-06-29 2006-04-26 贝克顿迪肯森公司 Intradermal delivery of vaccines and gene therapeutic agents via microcannula
BRPI0212496B8 (en) * 2001-09-12 2021-06-22 Becton Dickinson And Company Bd micro-needle-based pen-type device for drug delivery and method of use
US20040087992A1 (en) * 2002-08-09 2004-05-06 Vladimir Gartstein Microstructures for delivering a composition cutaneously to skin using rotatable structures
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
ES2374042T3 (en) * 2002-02-04 2012-02-13 Becton, Dickinson And Company DEVICE AND METHOD TO SUPPLY OR REMOVE A SUBSTANCE THROUGH THE SKIN.
JP2005518873A (en) * 2002-03-04 2005-06-30 ナノ パス テクノロジーズ リミテッド Apparatus and method for fluid transport across a biological barrier
US7047070B2 (en) * 2002-04-02 2006-05-16 Becton, Dickinson And Company Valved intradermal delivery device and method of intradermally delivering a substance to a patient
US7115108B2 (en) * 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7198606B2 (en) 2002-04-19 2007-04-03 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with analyte sensing
US7892185B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8641715B2 (en) 2002-05-31 2014-02-04 Vidacare Corporation Manual intraosseous device
US11337728B2 (en) 2002-05-31 2022-05-24 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
US7811260B2 (en) 2002-05-31 2010-10-12 Vidacare Corporation Apparatus and method to inject fluids into bone marrow and other target sites
US10973545B2 (en) 2002-05-31 2021-04-13 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
US8668698B2 (en) 2002-05-31 2014-03-11 Vidacare Corporation Assembly for coupling powered driver with intraosseous device
DE60328386D1 (en) 2002-05-31 2009-08-27 Vidacare Corp DEVICE AND METHOD FOR ACHIEVING BONE MARROW
ES2617576T3 (en) * 2002-08-29 2017-06-19 Becton, Dickinson And Company Substance administration through a rotating microabrasive system
US20040082934A1 (en) * 2002-08-30 2004-04-29 Pettis Ronald J. Method of controlling pharmacokinetics of immunomodulatory compounds
US20040106904A1 (en) * 2002-10-07 2004-06-03 Gonnelli Robert R. Microneedle array patch
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
ATE463202T1 (en) * 2002-12-30 2010-04-15 Hoffmann La Roche CAPILLARY TUBE TIP DESIGN TO SUPPORT BLOOD FLOW
US7578954B2 (en) * 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
DE602004028463D1 (en) 2003-05-30 2010-09-16 Pelikan Technologies Inc METHOD AND DEVICE FOR INJECTING LIQUID
US9504477B2 (en) 2003-05-30 2016-11-29 Vidacare LLC Powered driver
DK1633235T3 (en) 2003-06-06 2014-08-18 Sanofi Aventis Deutschland Apparatus for sampling body fluid and detecting analyte
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
AU2004264839B2 (en) * 2003-06-13 2009-06-04 Becton, Dickinson And Company Improved intra-dermal delivery of biologically active agents
ES2437565T3 (en) * 2003-06-30 2014-01-13 Alza Corporation Formulations for coated microprojections containing non-volatile counterions
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
MXPA06002159A (en) * 2003-08-26 2006-05-22 Becton Dickinson Co Methods for intradermal delivery of therapeutics agents.
AU2004271893B2 (en) 2003-08-28 2010-07-29 Becton, Dickinson And Company Intradermal injection device
EP1671096A4 (en) 2003-09-29 2009-09-16 Pelikan Technologies Inc Method and apparatus for an improved sample capture device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
KR20070001886A (en) * 2003-10-28 2007-01-04 알자 코포레이션 Delivery of polymer conjugates of therapeutic peptides and proteins via coated microprojections
WO2005044333A2 (en) * 2003-10-31 2005-05-19 Alza Corporation Self-actuating applicator for microprojection array
WO2005058393A2 (en) * 2003-12-18 2005-06-30 Novo Nordisk A/S Nozzle device with skin stretching means
CA2554232C (en) * 2003-12-22 2013-07-09 Paul Hadvary Dermallly affixed sensor device
EP1706171A1 (en) * 2003-12-29 2006-10-04 3M Innovative Properties Company Medical devices and kits including same
EP1706026B1 (en) 2003-12-31 2017-03-01 Sanofi-Aventis Deutschland GmbH Method and apparatus for improving fluidic flow and sample capture
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
CN1636505B (en) * 2004-01-09 2011-11-09 希森美康株式会社 Extracting implement, extracting apparatus, and apparatus for measuring blood sugar rate
GB0402131D0 (en) * 2004-01-30 2004-03-03 Isis Innovation Delivery method
US20050256499A1 (en) * 2004-03-03 2005-11-17 Pettis Ronald J Methods and devices for improving delivery of a substance to skin
US7377903B2 (en) * 2004-03-05 2008-05-27 Roche Diagnostics Operations, Inc. Split tip expression device
US20050203575A1 (en) * 2004-03-15 2005-09-15 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Skin microactivation system and method
EP1737357B1 (en) * 2004-03-24 2019-12-11 Corium, Inc. Transdermal delivery device
US7201723B2 (en) * 2004-03-25 2007-04-10 Roche Diagnostics Operations, Inc. Pulsating expression cap
AU2005243727B2 (en) * 2004-04-12 2011-04-28 Allergan, Inc. Multi-site injection system
EP1744784A2 (en) * 2004-05-11 2007-01-24 Becton, Dickinson and Company Formulations of anti-pain agents and methods of using the same
AU2005244734A1 (en) 2004-05-13 2005-12-01 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
EP1751546A2 (en) 2004-05-20 2007-02-14 Albatros Technologies GmbH & Co. KG Printable hydrogel for biosensors
WO2005120365A1 (en) 2004-06-03 2005-12-22 Pelikan Technologies, Inc. Method and apparatus for a fluid sampling device
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
ES2650188T3 (en) * 2004-06-10 2018-01-17 3M Innovative Properties Company Device and patch application kit
US7076987B2 (en) * 2004-08-05 2006-07-18 Becton, Dickinson And Company Method of producing tapered or pointed cannula
US7244270B2 (en) * 2004-09-16 2007-07-17 Evera Medical Systems and devices for soft tissue augmentation
US20060058891A1 (en) * 2004-09-16 2006-03-16 Lesh Michael D Transformable tissue bulking device
US7641688B2 (en) * 2004-09-16 2010-01-05 Evera Medical, Inc. Tissue augmentation device
US20080275569A1 (en) * 2004-09-16 2008-11-06 Evera Medical, Inc Tissue Augmentation Device
US20060058892A1 (en) * 2004-09-16 2006-03-16 Lesh Michael D Valved tissue augmentation implant
AU2012201016B2 (en) * 2004-11-18 2012-10-11 3M Innovative Properties Company Low-profile microneedle array applicator
AU2005306372B2 (en) 2004-11-18 2011-01-06 Kindeva Drug Delivery L.P. Method of contact coating a microneedle array
US8267889B2 (en) * 2004-11-18 2012-09-18 3M Innovative Properties Company Low-profile microneedle array applicator
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
CA2587386C (en) * 2004-11-18 2013-01-15 3M Innovative Properties Company Microneedle array applicator and retainer
CN101102809B (en) * 2004-11-18 2010-05-26 3M创新有限公司 Masking method for coating a microneedle array
WO2006066023A2 (en) * 2004-12-14 2006-06-22 C. R. Bard, Inc. Fast clear port
US7697967B2 (en) 2005-12-28 2010-04-13 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US10226207B2 (en) * 2004-12-29 2019-03-12 Abbott Diabetes Care Inc. Sensor inserter having introducer
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
US10035008B2 (en) 2005-04-07 2018-07-31 3M Innovative Properties Company System and method for tool feedback sensing
WO2007002523A2 (en) * 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
JP5144510B2 (en) * 2005-06-27 2013-02-13 スリーエム イノベイティブ プロパティズ カンパニー Microneedle array application device
US20070038148A1 (en) * 2005-08-11 2007-02-15 Joel Mechelke Sampling module for extracting interstitial fluid
US10548659B2 (en) 2006-01-17 2020-02-04 Ulthera, Inc. High pressure pre-burst for improved fluid delivery
US9358033B2 (en) 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US7967763B2 (en) * 2005-09-07 2011-06-28 Cabochon Aesthetics, Inc. Method for treating subcutaneous tissues
US8518069B2 (en) 2005-09-07 2013-08-27 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US20090093737A1 (en) * 2007-10-09 2009-04-09 Cabochon Aesthetics, Inc. Ultrasound apparatus with treatment lens
JP2007097980A (en) * 2005-10-07 2007-04-19 Univ Kansai Puncture device and production method thereof
EP1785090A1 (en) * 2005-11-10 2007-05-16 F.Hoffmann-La Roche Ag Lancet device and system for skin detection
US7842008B2 (en) * 2005-11-21 2010-11-30 Becton, Dickinson And Company Intradermal delivery device
US7885793B2 (en) 2007-05-22 2011-02-08 International Business Machines Corporation Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution
US20080195036A1 (en) * 2005-12-02 2008-08-14 Cabochon Aesthetics, Inc. Devices and methods for selectively lysing cells
US20080200864A1 (en) * 2005-12-02 2008-08-21 Cabochon Aesthetics, Inc. Devices and methods for selectively lysing cells
US9248317B2 (en) 2005-12-02 2016-02-02 Ulthera, Inc. Devices and methods for selectively lysing cells
EP1957132A4 (en) * 2005-12-08 2010-04-21 Nanopass Technologies Ltd Microneedle adapter for dosed drug delivery devices
CN101340940B (en) 2005-12-20 2012-07-18 诺沃-诺迪斯克有限公司 Skin retention device for a medical jet injection unit
US11298058B2 (en) 2005-12-28 2022-04-12 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US8048089B2 (en) 2005-12-30 2011-11-01 Edge Systems Corporation Apparatus and methods for treating the skin
US20100168501A1 (en) * 2006-10-02 2010-07-01 Daniel Rogers Burnett Method and apparatus for magnetic induction therapy
WO2011053607A1 (en) 2009-10-26 2011-05-05 Emkinetics, Inc. Method and apparatus for electromagnetic stimulation of nerve, muscle, and body tissues
US9339641B2 (en) 2006-01-17 2016-05-17 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US9610459B2 (en) * 2009-07-24 2017-04-04 Emkinetics, Inc. Cooling systems and methods for conductive coils
WO2007091671A1 (en) * 2006-02-09 2007-08-16 Matsushita Electric Industrial Co., Ltd. Blood test device
US10172644B2 (en) 2006-03-29 2019-01-08 Edge Systems Llc Devices, systems and methods for treating the skin
WO2014151104A1 (en) 2013-03-15 2014-09-25 Edge Systems Llc Devices, systems and methods for treating the skin
US9566088B2 (en) 2006-03-29 2017-02-14 Edge Systems Llc Devices, systems and methods for treating the skin
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
US20070276425A1 (en) * 2006-05-29 2007-11-29 Stanley Kim Painless Blood Sampling Lancet with Bundled Multiple Thin Needles
WO2007140381A2 (en) * 2006-05-29 2007-12-06 Stanley Kim Multiple needle system
JP2008022988A (en) * 2006-07-19 2008-02-07 Ritsumeikan Blood collection device
EP2066389B8 (en) 2006-09-12 2017-01-25 Vidacare LLC Bone marrow aspiration devices
US8944069B2 (en) 2006-09-12 2015-02-03 Vidacare Corporation Assemblies for coupling intraosseous (IO) devices to powered drivers
US9005102B2 (en) 2006-10-02 2015-04-14 Emkinetics, Inc. Method and apparatus for electrical stimulation therapy
US11224742B2 (en) 2006-10-02 2022-01-18 Emkinetics, Inc. Methods and devices for performing electrical stimulation to treat various conditions
US10786669B2 (en) 2006-10-02 2020-09-29 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
WO2008042902A2 (en) * 2006-10-02 2008-04-10 Emkinetics, Inc. Method and apparatus for magnetic induction therapy
KR20080051342A (en) * 2006-12-05 2008-06-11 연세대학교 산학협력단 A microneedle device and methods for applicating it
JP2008154849A (en) * 2006-12-25 2008-07-10 Ritsumeikan Injector
AU2008209537B2 (en) * 2007-01-22 2013-01-31 Corium Pharma Solutions, Inc. Applicators for microneedle arrays
JP4978245B2 (en) * 2007-03-08 2012-07-18 凸版印刷株式会社 Needle-shaped body, needle-shaped body manufacturing method, and drug transport device
WO2008114220A2 (en) * 2007-03-19 2008-09-25 Insuline Medical Ltd. Device for drug delivery and associated connections thereto
US8827979B2 (en) * 2007-03-19 2014-09-09 Insuline Medical Ltd. Drug delivery device
US9220837B2 (en) * 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
US20100292557A1 (en) * 2007-03-19 2010-11-18 Benny Pesach Method and device for substance measurement
US8622991B2 (en) * 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
CA2686093C (en) 2007-04-16 2018-05-08 Corium International, Inc. Solvent-cast microneedle arrays containing active
JP5044334B2 (en) * 2007-09-06 2012-10-10 株式会社ニコン Collection container
JP5222512B2 (en) * 2007-09-19 2013-06-26 凸版印刷株式会社 Micro needle tip
US20090093723A1 (en) * 2007-10-05 2009-04-09 Cabochon Aesthetics, Inc. Ultrasound device including dispenser
US8439940B2 (en) 2010-12-22 2013-05-14 Cabochon Aesthetics, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
US20090093738A1 (en) * 2007-10-09 2009-04-09 Cabochon Aesthetics, Inc. Device and method for monitoring a treatment area
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
JP5178132B2 (en) * 2007-10-11 2013-04-10 キヤノン株式会社 Image processing system and image processing method
US20090247984A1 (en) * 2007-10-24 2009-10-01 Masimo Laboratories, Inc. Use of microneedles for small molecule metabolite reporter delivery
US8409133B2 (en) * 2007-12-18 2013-04-02 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
WO2009079712A1 (en) 2007-12-24 2009-07-02 The University Of Queensland Coating method
WO2009088884A1 (en) 2008-01-04 2009-07-16 Edge Systems Corporation Apparatus and method for treating the skin
WO2009097451A1 (en) 2008-01-29 2009-08-06 Edge Systems Corporation Apparatus and method for treating the skin
US20090198329A1 (en) 2008-02-01 2009-08-06 Kesten Randy J Breast implant with internal flow dampening
US20090198331A1 (en) * 2008-02-01 2009-08-06 Kesten Randy J Implantable prosthesis with open cell flow regulation
EP2265324B1 (en) 2008-04-11 2015-01-28 Sanofi-Aventis Deutschland GmbH Integrated analyte measurement system
WO2009130926A1 (en) * 2008-04-22 2009-10-29 南部化成株式会社 Endermic method, needle organizer and endermic injector device
CN101896121B (en) * 2008-05-09 2012-02-29 松下电器产业株式会社 Skin incision apparatus and method for incising skin by skin incision apparatus
CN101938941B (en) 2008-05-13 2012-07-25 松下电器产业株式会社 Skin incision instrument
US20100010484A1 (en) * 2008-07-14 2010-01-14 Primaeva Medical, Inc. Devices and methods for percutaneous energy delivery
US20100106063A1 (en) * 2008-10-29 2010-04-29 Cabochon Aesthetics, Inc. Ultrasound Enhancing Target for Treating Subcutaneous Tissue
JP5713913B2 (en) * 2008-11-07 2015-05-07 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ Syringe housing for easy drug injection
MX2011004817A (en) 2008-11-07 2011-07-28 Insuline Medical Ltd Device and method for drug delivery.
JP5600115B2 (en) 2008-12-09 2014-10-01 ベクトン・ディキンソン・アンド・カンパニー Drug delivery system to increase lever and gear force for high pressure injection system
JP2012511391A (en) 2008-12-09 2012-05-24 ベクトン・ディキンソン・アンド・カンパニー Two-load medicine delivery device for high-pressure injection
JP5662337B2 (en) 2008-12-09 2015-01-28 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ Open and close valve drug delivery system for high pressure injection
US9238112B2 (en) 2008-12-09 2016-01-19 Becton, Dickinson And Company Multi-stroke delivery pumping mechanism for a drug delivery device for high pressure injections
KR101033513B1 (en) * 2009-01-20 2011-05-09 (주)마이티시스템 Case for the effective component delivery using micro-needle
US9440024B2 (en) * 2009-01-27 2016-09-13 Becton, Dickinson And Company Infusion set with anesthetic compound
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US8167280B2 (en) * 2009-03-23 2012-05-01 Cabochon Aesthetics, Inc. Bubble generator having disposable bubble cartridges
US20100256596A1 (en) * 2009-04-07 2010-10-07 Cabochon Aesthetics, Inc. Fiber growth promoting implants for reducing the appearance of cellulite
US20110006458A1 (en) * 2009-04-24 2011-01-13 Corium International, Inc. Methods for manufacturing microprojection arrays
EP2451367B1 (en) 2009-07-08 2020-01-22 Edge Systems Corporation Devices for treating the skin using time-release substances
JP5663792B2 (en) * 2009-08-07 2015-02-04 株式会社 メドレックス Kenzan microneedle applicator device
US11096708B2 (en) 2009-08-07 2021-08-24 Ulthera, Inc. Devices and methods for performing subcutaneous surgery
US9358064B2 (en) 2009-08-07 2016-06-07 Ulthera, Inc. Handpiece and methods for performing subcutaneous surgery
US8409147B2 (en) * 2009-08-22 2013-04-02 Joseph Wayne Kraft Rapid local anesthesia linear injection device
US8088108B2 (en) * 2009-08-22 2012-01-03 Joseph Wayne Kraft Rapid local anesthesia injection cone
JP2011045565A (en) * 2009-08-27 2011-03-10 Nanbu Plastics Co Ltd Liquid medicine injector
WO2011041463A2 (en) * 2009-09-30 2011-04-07 Dexcom, Inc. Transcutaneous analyte sensor
DE102009046581A1 (en) * 2009-11-10 2011-05-12 Robert Bosch Gmbh Manufacturing method for a porous microneedle array and corresponding porous microneedle array and corresponding substrate composite
RU2539991C2 (en) * 2009-12-16 2015-01-27 Кронтек Фарма Аб Injector and device
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
CA2798145C (en) 2010-05-04 2022-10-18 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
CN102971038B (en) 2010-05-04 2016-02-03 考里安国际公司 Micropin applicator
US8588884B2 (en) 2010-05-28 2013-11-19 Emkinetics, Inc. Microneedle electrode
US9943673B2 (en) 2010-07-14 2018-04-17 Vaxxas Pty Limited Patch applying apparatus
JP5770055B2 (en) * 2010-09-29 2015-08-26 富士フイルム株式会社 Method for manufacturing needle-like array transdermal absorption sheet
US9017289B2 (en) 2010-11-03 2015-04-28 Covidien Lp Transdermal fluid delivery device
US20130296791A1 (en) * 2011-01-18 2013-11-07 Michael Segev Medication delivery assembly
AU2012236099A1 (en) 2011-03-31 2013-10-03 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
JP4923156B1 (en) * 2011-05-24 2012-04-25 エム・エフ・ヴィ株式会社 Application tool
WO2012166965A2 (en) * 2011-05-31 2012-12-06 Microlin, Llc An apparatus and method for dermal delivery
EP2717945A4 (en) * 2011-06-09 2015-10-28 3M Innovative Properties Co Microstructure device with removable microstructure patch
GB201109620D0 (en) * 2011-06-09 2011-07-20 Ardehali Massoud H Injection apparatus
US20120316499A1 (en) * 2011-06-10 2012-12-13 Erich George Brehm Fluid Delivery System
CN103717249B (en) 2011-06-15 2017-03-22 克洛恩泰克制药股份公司 Injection needle and device
US9730729B2 (en) 2011-07-11 2017-08-15 Teleflex Medical Devices S.A R.L. Sternal locators and associated systems and methods
WO2013046868A1 (en) * 2011-09-29 2013-04-04 テルモ株式会社 Syringe
EP3881781B1 (en) 2011-10-12 2023-03-29 Vaxxas Pty Limited Delivery device
US20140296797A1 (en) * 2011-11-04 2014-10-02 Nipro Corporation Injection needle
EP2589401A1 (en) * 2011-11-04 2013-05-08 Fiderm S.r.l. (Ricerca e Technogie in Scienze Dermatologiche) Device for controlling the depth and reducing the pain of injections
EP2776095B1 (en) * 2011-11-07 2022-01-05 Eli Lilly And Company Injection devices with ergonomic enhancements
EP2791160B1 (en) 2011-12-16 2022-03-02 ModernaTX, Inc. Modified mrna compositions
WO2013151766A1 (en) * 2012-04-02 2013-10-10 Medtronic, Inc. Therapy for kidney disease and/or heart failure by intradermal infusion
EP2890304B1 (en) * 2012-08-14 2019-06-26 The General Hospital Corporation Apparatus for tissue harvesting
CN103673821A (en) * 2012-09-03 2014-03-26 致茂电子(苏州)有限公司 Probe compression stroke measurement method and related circuit test system
EP2906284B8 (en) * 2012-10-10 2021-01-20 Kindeva Drug Delivery L.P. Force-controlled applicator for applying a microneedle device to skin
US20140107450A1 (en) 2012-10-12 2014-04-17 Dexcom, Inc. Sensors for continuous analyte monitoring, and related methods
US20140213866A1 (en) 2012-10-12 2014-07-31 Dexcom, Inc. Sensors for continuous analyte monitoring, and related methods
JP6549035B2 (en) * 2012-10-19 2019-07-24 アムゲン・インコーポレーテッド Improved auto-injector
LT2922554T (en) 2012-11-26 2022-06-27 Modernatx, Inc. Terminally modified rna
US11052231B2 (en) 2012-12-21 2021-07-06 Corium, Inc. Microarray for delivery of therapeutic agent and methods of use
KR102244475B1 (en) * 2013-01-08 2021-04-23 쓰리엠 이노베이티브 프로퍼티즈 컴파니 Applicator for applying a microneedle device to skin
JP2016504050A (en) 2013-01-17 2016-02-12 モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． Signal sensor polynucleotide for modification of cell phenotype
EP2957315B1 (en) 2013-02-13 2019-11-13 Hisamitsu Pharmaceutical Co., Inc. Microneedle array
CA2900505C (en) 2013-02-20 2023-10-24 Cytrellis Biosystems, Inc. Methods and devices for skin tightening
US10183156B2 (en) * 2013-02-28 2019-01-22 Sorrento Therapeutics, Inc. Transdermal drug delivery device
BR112015022253B1 (en) 2013-03-12 2022-03-15 Corium, Inc microprojection applicator
EP2968391A1 (en) 2013-03-13 2016-01-20 Moderna Therapeutics, Inc. Long-lived polynucleotide molecules
JP2016514133A (en) 2013-03-15 2016-05-19 コリウム インターナショナル， インコーポレイテッド MICROARRAY CONTAINING FINE STRUCTURE CONTAINING NO POLYMER, MANUFACTURING METHOD AND USE METHOD
KR102341601B1 (en) 2013-03-15 2021-12-21 코리움, 인크. Microarray for delivery of therapeutic agent and methods of use
US10238812B2 (en) 2013-03-15 2019-03-26 Edge Systems Llc Skin treatment systems and methods using needles
CA2903459C (en) 2013-03-15 2024-02-20 Corium International, Inc. Multiple impact microprojection applicators and methods of use
JP2016512754A (en) 2013-03-15 2016-05-09 コリウム インターナショナル， インコーポレイテッド Microarray, method of use and manufacturing for delivery of therapeutic agents
CA3005826C (en) 2013-04-15 2021-11-23 Becton, Dickinson And Company Biological fluid collection device and biological fluid separation and testing system
BR112015026262B1 (en) 2013-04-15 2022-10-18 Becton, Dickinson And Company BIOLOGICAL FLUID SAMPLING TRANSFER DEVICE AND BIOLOGICAL FLUID SEPARATION AND TESTING SYSTEM
GB201307262D0 (en) 2013-04-23 2013-05-29 Chowdhury Dewan F H Device for containment and release of drug formulation
US9474849B2 (en) * 2013-06-07 2016-10-25 John Richard Parker Apparatus and method for reducing incidence of tick borne infections
US20150182703A1 (en) * 2013-12-02 2015-07-02 Biltmore Technologies, Inc. Nanofluidic delivery system
DE102013021058B4 (en) 2013-12-18 2017-10-12 Gerresheimer Regensburg Gmbh Device for applying a needle array to biological tissue
JP6167048B2 (en) * 2014-02-14 2017-07-19 株式会社ダイセル Needleless syringe
US20150289788A1 (en) 2014-04-10 2015-10-15 Dexcom, Inc. Sensors for continuous analyte monitoring, and related methods
JP5896093B1 (en) * 2014-04-14 2016-03-30 凸版印刷株式会社 Injection device
US10004845B2 (en) 2014-04-18 2018-06-26 Becton, Dickinson And Company Split piston metering pump
US9416775B2 (en) 2014-07-02 2016-08-16 Becton, Dickinson And Company Internal cam metering pump
EP2982302B1 (en) * 2014-08-05 2018-05-23 Roche Diabetes Care GmbH Medical applicator
WO2016036866A1 (en) 2014-09-04 2016-03-10 Corium International, Inc. Microstructure array, methods of making, and methods of use
US11324534B2 (en) 2014-11-14 2022-05-10 Cytrellis Biosystems, Inc. Devices and methods for ablation of the skin
EP4324414A3 (en) 2014-12-23 2024-05-01 HydraFacial LLC Devices and methods for treating the skin using a rollerball or a wicking member
US10179229B2 (en) 2014-12-23 2019-01-15 Edge Systems Llc Devices and methods for treating the skin using a porous member
US11147954B2 (en) 2015-02-02 2021-10-19 Vaxxas Pty Limited Microprojection array applicator and method
JPWO2016129184A1 (en) * 2015-02-13 2017-04-27 株式会社 メドレックス Microneedle puncture device and microneedle patch application device
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
CN107920948A (en) 2015-07-08 2018-04-17 边缘系统有限公司 For trichogenous devices, systems, and methods
WO2017045031A1 (en) 2015-09-18 2017-03-23 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
KR101711417B1 (en) * 2015-10-14 2017-03-14 인하대학교 산학협력단 Apparatus for inserting surgical micro staple into soft tissues
US20170165434A1 (en) * 2015-12-10 2017-06-15 Xiamen Brana Design Co., Ltd. Multi-needle needle assembly
WO2017110815A1 (en) 2015-12-21 2017-06-29 株式会社 メドレックス Microneedle patch applicator and housing for same
US10500351B2 (en) 2016-02-12 2019-12-10 Shawn Michael Michels Aid for subcutaneous tissue injection and process of effecting the injection with the aid
US10220195B2 (en) * 2016-06-08 2019-03-05 Eclipse Medcorp, Llc Radio frequency needling device for use with disposable needle cartridges
JP6670207B2 (en) * 2016-08-26 2020-03-18 日本発條株式会社 Puncture device
JP2019529043A (en) 2016-09-21 2019-10-17 サイトレリス バイオシステムズ，インコーポレーテッド Beauty skin resurfacing apparatus and method
EP3315156A1 (en) * 2016-11-01 2018-05-02 Sanofi-Aventis Deutschland GmbH Medicament delivery device
WO2018111621A1 (en) 2016-12-16 2018-06-21 Kimberly-Clark Worldwide, Inc. A fluid delivery apparatus having a controller assembly and method of use
AU2017378022B2 (en) 2016-12-16 2023-06-29 Vivasor, Inc. Fluid delivery apparatus and method of assembly
ES2943307T3 (en) 2016-12-16 2023-06-12 Sorrento Therapeutics Inc Fluid delivery apparatus including a microneedle array suitable for treating a migraine or cluster headache
US10569010B2 (en) 2016-12-16 2020-02-25 Sorrento Therapeutics, Inc. Fluid delivery apparatus having a gas extraction device and method of use
PL3554621T3 (en) * 2016-12-16 2022-06-20 Sorrento Therapeutics, Inc. Attachment band for a fluid delivery apparatus and method of use
EP3554620A4 (en) 2016-12-16 2020-07-15 Sorrento Therapeutics, Inc. Application device for a fluid delivery apparatus and method of use
US10751484B2 (en) * 2017-01-26 2020-08-25 Allergan Industrie, Sas Needle array device
JP7152787B2 (en) 2017-03-31 2022-10-13 ヴァクザス ピーティーワイ リミテッド Apparatus and method for coating surfaces
US11039823B2 (en) 2017-05-03 2021-06-22 Z Surgical Llc Minimal-access percutaneous and self-retracting surgical system
CA3065371A1 (en) 2017-06-13 2018-12-20 Vaxxas Pty Limited Quality control of substrate coatings
US11464957B2 (en) 2017-08-04 2022-10-11 Vaxxas Pty Limited Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (MAP)
WO2019146618A1 (en) * 2018-01-24 2019-08-01 コスメディ製薬株式会社 Tight-binding device for micro-needle
CN111836662A (en) * 2018-03-13 2020-10-27 美德阿利克斯株式会社 Adhesive member and microneedle patch
JP2019170870A (en) * 2018-03-29 2019-10-10 凸版印刷株式会社 Microneedle
JP1632957S (en) 2018-10-30 2019-06-03
US11369409B2 (en) * 2019-10-03 2022-06-28 Medline Industries, Lp System and method for fluid ingress control for a skin grafting system
WO2021081392A1 (en) * 2019-10-24 2021-04-29 Hopkins Janine Applicator device and methods of use
US20230028295A1 (en) * 2019-12-18 2023-01-26 Uprax Microsolutions B.V. Applicators and methods for applying a microneedle patch to a skin of a subject, and microneedle patches
WO2021177317A1 (en) * 2020-03-02 2021-09-10 シンクランド株式会社 Microneedle sheet and transdermal absorption type pharmaceutical
US20210353878A1 (en) * 2020-05-14 2021-11-18 Jonathan Robin Fugo Hypodermic device with an array of hypodermic needles
WO2021244835A1 (en) * 2020-06-04 2021-12-09 Shl Medical Ag Medicament delivery device component or add-on module for medicament delivery device
US20230321360A1 (en) 2020-09-30 2023-10-12 Shiseido Company, Ltd. Needle-shaped projection-including part
USD1016615S1 (en) 2021-09-10 2024-03-05 Hydrafacial Llc Container for a skin treatment device
WO2023168419A2 (en) * 2022-03-03 2023-09-07 Deka Products Limited Partnership Systems, methods, and apparatuses for medical agent administration
WO2023205341A1 (en) * 2022-04-22 2023-10-26 The Board Of Trustees Of The Leland Stanford Junior University Compliant polymeric structures having polymeric microneedles and methods for making and using same

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1216813A (en) 1969-02-21 1970-12-23 Shozo Narusawa Transcutaneous injection device
CH582884A5 (en) * 1973-12-10 1976-12-15 Hoffmann La Roche
CA1272423A (en) * 1986-02-25 1990-08-07 Peter C. Lord Soft cannula subcutaneous injection set and method of making same
US4695273A (en) 1986-04-08 1987-09-22 I-Flow Corporation Multiple needle holder and subcutaneous multiple channel infusion port
FR2612401A1 (en) 1987-03-16 1988-09-23 Denance Raymond Stabiliser end-piece for hypodermic needle comprising a means acting as a prop for regulating the penetration as a function of attack of the needle in the skin
EP0429842B1 (en) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
JPH0626570B2 (en) * 1991-01-31 1994-04-13 参天製薬株式会社 Double layer syringe barrel
JP3590805B2 (en) * 1993-11-10 2004-11-17 株式会社ニコン Blood collection device
WO1996037155A1 (en) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical device and method for enhancing delivery of compounds through the skin
SE9502285D0 (en) 1995-06-22 1995-06-22 Pharmacia Ab Improvements related to injections
JP2718408B2 (en) * 1995-09-20 1998-02-25 日本電気株式会社 Leachate suction device
ES2297858T3 (en) * 1996-05-17 2008-05-01 Roche Diagnostics Operations, Inc. DISPOSABLE ELEMENT THAT IS USED IN A BODY LIQUID SAMPLING DEVICE.
WO1997048440A1 (en) 1996-06-18 1997-12-24 Alza Corporation Device for enhancing transdermal agent delivery or sampling
IT1298087B1 (en) 1998-01-08 1999-12-20 Fiderm S R L DEVICE FOR CHECKING THE PENETRATION DEPTH OF A NEEDLE, IN PARTICULAR APPLICABLE TO A SYRINGE FOR INJECTIONS
JP3382853B2 (en) * 1998-04-09 2003-03-04 松下電器産業株式会社 Body fluid testing device
CA2229522A1 (en) 1998-04-15 1999-10-15 Thomas Randall Inkpen Needle aid
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
AU767122B2 (en) * 1998-06-10 2003-10-30 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
WO2000074763A2 (en) 1999-06-04 2000-12-14 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
ATE310561T1 (en) 1999-12-10 2005-12-15 Alza Corp APPARATUS AND METHOD FOR IMPROVING MICRONEEDLE SKIN PIERCING

Also Published As

Publication number Publication date
ATE315944T1 (en) 2006-02-15
JP4746818B2 (en) 2011-08-10
EP1289588A1 (en) 2003-03-12
DE60116764D1 (en) 2006-04-06
US6537242B1 (en) 2003-03-25
DE60116764T2 (en) 2006-11-02
WO2001093931A1 (en) 2001-12-13
EP1289588B1 (en) 2006-01-18
ES2254435T3 (en) 2006-06-16
JP2003534881A (en) 2003-11-25

Similar Documents

Publication Publication Date Title
AU2001275260A1 (en) Method and apparatus for enhancing penetration of a puncturing member into the intradermal space
US10625029B2 (en) Needle system
DE60106261D1 (en) DELIVERY DEVICE WITH MICRO NEEDLES FOR TRANSDERMAL ADMINISTRATION OF A SUBSTANCE
US6660018B2 (en) Multiple lancet device
ATE304878T1 (en) MICROSTRUCTURES FOR CUTANEOUS ADMINISTRATION OF AN AGENT TO THE SKIN
WO2004110518A3 (en) Rapid analgesia for skin puncture
DE602006005636D1 (en)
EP1938750A3 (en) Method of therapeutic drug monitoring
TW200517156A (en) Pretreatment method and system for enhancing transdermal drug delivery
WO2008085756A3 (en) Automated delivery of a therapeutic or cosmetic substance to cutaneous, subcutaneous and intramuscular tissue regions
WO2005039384A3 (en) Method and system for cellular transplantation
WO2002085451A3 (en) Handheld apparatus for transdermal drug delivery and analyte extraction
IL158480A0 (en) Microprojection array having a beneficial agent containing coating
WO2004019777A3 (en) Substance delivery via rotating mocroabrading surface
AU2002312380A1 (en) Device for manipulating a needle or abrader array
CN110354340A (en) It is a kind of automatic injection and the adjustable syringe of paracentesis depth
WO2009070657A3 (en) Electro collagen induction therapy device
PL376767A1 (en) Apparatus for patient's skin punctures
CN108014398A (en) Auxiliary injection unit and its method of work
CN111956951A (en) Iontophoresis micro-needle medicine patch and preparation method thereof
AU2003246537A1 (en) Device for needle-free injection of a medium into the tissue of a human or an animal, device for needle free production of an injection channel and method for the needle free injection of a medium in the tissue
CN205494570U (en) Skin shallow layer pressurization injection device
CN104922791A (en) Noninvasive acupuncture patch and preparation method thereof
WO2002058556A8 (en) Method and apparatus for micro-sampling
KR101947624B1 (en) Multi type micro-needle