WO2013046868A1 - Syringe - Google Patents

Syringe Download PDF

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Publication number
WO2013046868A1
WO2013046868A1 PCT/JP2012/068003 JP2012068003W WO2013046868A1 WO 2013046868 A1 WO2013046868 A1 WO 2013046868A1 JP 2012068003 W JP2012068003 W JP 2012068003W WO 2013046868 A1 WO2013046868 A1 WO 2013046868A1
Authority
WO
WIPO (PCT)
Prior art keywords
outer cylinder
living body
puncture needle
syringe
pusher
Prior art date
Application number
PCT/JP2012/068003
Other languages
French (fr)
Japanese (ja)
Inventor
広孝 大橋
陽一郎 岩瀬
立川　浩一
Original Assignee
テルモ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by テルモ株式会社 filed Critical テルモ株式会社
Publication of WO2013046868A1 publication Critical patent/WO2013046868A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/422—Desensitising skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A61M2005/31508—Means for blocking or restricting the movement of the rod or piston provided on the piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3287—Accessories for bringing the needle into the body; Automatic needle insertion

Definitions

  • the present invention relates to a syringe.
  • the syringe is generally composed of an outer cylinder, a gasket that can slide in the outer cylinder, and a plunger that moves the gasket.
  • the outer cylinder has a trunk
  • Such a syringe is configured to move the gasket toward the distal end side by pushing the pusher into the outer cylinder, thereby guiding the chemical stored in the outer cylinder to the outside of the outer cylinder from the opening of the mouth. (For example, refer to Patent Document 1).
  • Patent Document 1 The syringe described in Patent Document 1 is used as follows, for example. With the puncture needle connected to the mouth, hold the outer tube with four fingers except the thumb, puncture the skin with the thumb on the pusher, and maintain the state with the thumb. The drug solution is administered by pushing the pusher. In addition, with the puncture needle connected to the mouth, the outer tube is held between the index finger and the middle finger, and the puncture needle is punctured into the skin with the thumb placed on the pusher, and the thumb is maintained while maintaining the state. The drug solution is administered by pushing the pusher in.
  • An object of the present invention is to provide a syringe with excellent operability.
  • the present invention provides an outer cylinder having a mouth on the tip side, A puncture needle connected to the mouth and having a needle tip capable of puncturing a living body; A gasket that can slide in the outer cylinder; A chemical solution stored in a space surrounded by the outer cylinder and the gasket; An abutting portion that abuts the living body prior to puncturing the living body with the puncture needle; A pusher which is provided so as to be movable in the longitudinal direction of the outer cylinder with respect to the outer cylinder, and which moves the gasket toward the distal end side of the outer cylinder; Movement restricting means for restricting movement of the pusher toward the distal end side with respect to the outer cylinder, The pusher covers at least a part of the outer periphery of the outer cylinder and is connected to the cylindrical gripping part provided to be movable in the longitudinal direction of the outer cylinder with respect to the outer cylinder.
  • a pressing portion that is inserted into the outer cylinder and moves the gasket toward the distal end side by moving the gripping portion toward the distal end side with respect to the outer cylinder;
  • the contact portion has an accommodating portion that opens to the distal end side and accommodates the puncture needle inside.
  • the restriction by the movement restricting means is released, and the pusher is distal to the outer cylinder.
  • the syringe is configured to move to the side, whereby the gasket moves to the distal end side, and the drug solution is injected into the living body from the puncture needle.
  • the contact portion has a dome-shaped base and a plurality of slits formed from the outer periphery to the center of the base.
  • the contact portion is crushed in the longitudinal direction of the outer cylinder, and the opening of the storage portion is expanded. It is preferable to deform it.
  • the contact portion has a plurality of divided pieces divided by the slit, and a weakened portion provided in the middle of the extending direction of the divided pieces, and the pusher is It is preferable that when the first pressing force is pushed into the living body, the divided piece is deformed so as to be bent at the fragile portion.
  • the abutting portion is broken when the divided piece is bent at the weakened portion.
  • the contact portion protrudes into the storage portion, and has a protruding portion provided to surround the puncture needle,
  • the protrusion preferably presses the living body in a state where the contact portion is deformed by the first pressing force.
  • the movement restricting means is configured to be damaged by the second pressing force.
  • FIG. 1 is a longitudinal sectional view showing a first embodiment of the syringe of the present invention.
  • FIG. 2 is a perspective view of a contact portion of the syringe shown in FIG.
  • FIG. 3 is a schematic diagram illustrating an example of a method of using the syringe shown in FIG.
  • FIG. 4 is a longitudinal sectional view showing a second embodiment of the syringe of the present invention.
  • FIG. 1 is a longitudinal sectional view showing a first embodiment of the syringe of the present invention
  • FIG. 2 is a perspective view of an abutting portion of the syringe shown in FIG. 1
  • FIG. 3 is a method of using the syringe shown in FIG. It is a schematic diagram explaining an example.
  • the upper side in FIGS. 1 and 3 is referred to as a “base end” and the lower side is referred to as a “tip”.
  • the state where no syringe is used and no external force is applied to the syringe that is, the state shown in FIG. 1 is also referred to as “unused state”.
  • a syringe used for “intradermal injection” in which the drug solution 100 is administered between the epidermis and the dermis will be described as a representative.
  • the use of the syringe of the present invention is not limited to this, and for example, a drug solution You may apply to "subcutaneous injection” which administers 100 to subcutaneous tissue, and “muscular injection” which administers the chemical
  • a syringe 1 shown in FIG. 1 is a prefilled syringe in which a chemical solution 100 is stored in advance.
  • a syringe 1 includes an outer cylinder 2, a puncture needle 6 provided with the outer cylinder 2, a gasket 3 that can slide in the outer cylinder 2, a pusher 4 that moves the gasket 3, and a puncture needle.
  • a contact portion 5 that contacts the skin and a spring member (biasing means) 9 that biases the outer cylinder 2 against the contact portion 5 are provided prior to puncturing 6, a contact portion 5 that contacts the skin and a spring member (biasing means) 9 that biases the outer cylinder 2 against the contact portion 5 are provided.
  • a liquid chemical solution 100 is stored in advance in a space 11 surrounded by the outer cylinder 2 and the gasket 3, which is located on the tip side of the gasket 3.
  • a vitamin agent total vitamin agent
  • various amino acids antithrombotic agents like heparin, insulin, antibiotics, an antitumor agent, an analgesic agent, a cardiotonic agent, an intravenous anesthetic agent, Antiparkinson agents, ulcer treatment agents, corticosteroid agents, arrhythmia agents, correction electrolytes, protease inhibitors, thromboxane synthesis inhibitors and the like can be mentioned.
  • the amount of the chemical solution 100 stored in the space is not particularly limited, but is about 0.02 to 2.0 mL, for example.
  • the outer cylinder 2 is composed of a bottomed cylindrical member. As shown in FIG. 1, the outer cylinder 2 includes a barrel portion 21 having a bottom portion 211, a plate-like flange 27 provided on the outer periphery of the proximal end of the barrel portion 21, and a central portion of the bottom portion 211. 21 and a mouth portion 22 having a reduced diameter with respect to 21, and these are integrally formed.
  • Examples of the constituent material of the outer cylinder 2 include polyvinyl chloride, polyethylene, polypropylene, cyclic polyolefin, polystyrene, poly- (4-methylpentene-1), polycarbonate, acrylic resin, acrylonitrile-butadiene-styrene copolymer, Various resins such as polyesters such as polyethylene terephthalate and polyethylene naphthalate, butadiene-styrene copolymers, and polyamides (for example, nylon 6, nylon 6,6, nylon 6,10, nylon 12) can be mentioned. Resin such as polypropylene, cyclic polyolefin, polyester, and poly- (4-methylpentene-1) is preferable because it is easy to mold.
  • the outer cylinder 2 is substantially transparent in order to ensure internal visibility.
  • the puncture needle 6 is provided at the mouth portion 22 of the outer cylinder, and the needle tip projects from the mouth portion 22 toward the distal end side.
  • the puncture needle 6 has a needle tip that can puncture a living body, and the medical solution 100 stored in the outer cylinder 2 can be injected (administered) into the living body by puncturing the living body with the needle tip. .
  • the puncture needle 6 has a size of 26 to 33 G (outer diameter: 0.2 to 0.45 mm) based on the ISO medical needle tube standard (ISO9626: 1991 / Amd.1: 2001 (E)). Is preferably used, and more preferably 30 to 33G in size.
  • the length of the portion of the puncture needle 6 protruding from the mouth portion 22, that is, the depth of puncture into the living body is not particularly limited, but is within the range of 0.5 mm to 3.0 mm. It is preferably set. Since the thickness of the epidermis is approximately 0.5 to 3.0 mm, setting the puncture depth within the above range makes the syringe 1 more suitable for intradermal injection.
  • the constituent material of the puncture needle 6 is not particularly limited.
  • various metal materials such as stainless steel, aluminum or an aluminum alloy, titanium or a titanium alloy, a superelastic alloy such as a Ni—Ti alloy, polyphenylene sulfide, and the like.
  • Various hard resin materials are mentioned.
  • the puncture needle 6 is covered with a cap 7. Thereby, the puncture needle 6 is protected and erroneous puncture of the puncture needle 6 can be prevented.
  • the cap 7 is used by being removed when the syringe 1 is used. Considering ease of removal, it is preferable that the cap 7 has a shape protruding from the tip of the contact portion 5.
  • a gasket 3 made of an elastic material is accommodated in the outer cylinder 2.
  • a plurality of ring-shaped protrusions are formed on the entire outer periphery of the gasket 3, and the protrusions slide while being in close contact with the inner peripheral surface of the outer cylinder 2. While holding more reliably, slidability can be improved.
  • the constituent material of the gasket 3 is not particularly limited.
  • various rubber materials such as natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, silicone rubber, polyurethane, polyester, polyamide,
  • elastic materials such as various thermoplastic elastomers such as olefins and styrenes, or mixtures thereof.
  • the contact portion 5 has a function of stabilizing the posture of the syringe 1 by bringing it into contact with the epidermis (living body) prior to the puncture of the puncture needle 6 when using the syringe 1.
  • such a contact portion 5 is fixed to the mouth portion 22 of the outer cylinder 2. Further, the contact portion 5 has a dome shape (umbrella shape) curved toward the distal end side, and is configured to be elastically deformable. Moreover, the contact part 5 has the accommodating part 5a comprised by the recessed part open
  • the contact portion 5 can be brought into contact with the entire periphery of the portion where the puncture needle 6 is punctured. Therefore, the posture of the syringe 1 is stable, and the puncture needle 6 can be maintained in a posture substantially perpendicular to the epidermis.
  • the height L of the storage portion 5a in the unused state is not particularly limited as long as the puncture needle 6 can be stored, but before the puncture needle 6 is punctured, the contact portion 5 is applied with an appropriate pressing force by the epidermis. Is set so that the puncture needle 6 is punctured securely.
  • the height L is appropriately set according to the opening diameter of the storage portion 5a. For example, when the opening diameter is about 10 mm, the height L is set within a range of 0.75 mm to 2.6 mm. preferable.
  • such a contact portion 5 includes a dome-shaped base 51 and a plurality of slits (cuts) 52 formed radially from the outer periphery of the base 51 toward the center.
  • a plurality of divided pieces 53 that are divided by the slits 52 and that have free ends are formed on the outer peripheral portion of the base 51.
  • a through hole 511 is formed at the center of the base 51, and the mouth portion 22 of the outer cylinder 2 is fitted into the through hole 511. Thereby, the contact part 5 is fixed to the outer cylinder 2.
  • mouth part 22 is not specifically limited, For example, you may fix by screwing.
  • the slit 52 is formed to facilitate the deformation of the contact portion 5.
  • the number of slits 52 varies depending on the size of the contact portion 5 and the like, but is preferably about 4 to 16, for example.
  • the base 51 has a protruding portion 512 that protrudes into the storage portion 5a.
  • the protruding portion 512 is formed in a substantially annular shape centering on the mouth portion 22, but is divided into a plurality of portions by the slit 52. In the unused state, the distal end of each projecting portion 512 is located closer to the proximal end than the opening of the storage portion 5a.
  • the tip of puncture needle 6 is located in a region surrounded by a plurality of protrusions 512.
  • the contact portion 5 when the contact portion 5 is pressed against the outer skin by a force (first pressing force; external force G1 described later) having a predetermined magnitude or more, the contact portion 5 is crushed in that direction, The opening diameter is deformed so as to increase. And when the contact part 5 deform
  • first pressing force external force G1 described later
  • the constituent material of the contact portion 5 is not particularly limited as long as it can be elastically deformed.
  • the same material as the constituent material of the outer cylinder 2 can be used.
  • the pusher 4 is provided so as to be movable in the longitudinal direction of the outer cylinder 2 with respect to the outer cylinder 2. As shown in FIG. 1, the pusher 4 includes a grip portion 41 that is gripped by the user and a pressing portion 42 that presses the gasket 3. In the present embodiment, the grip portion 41 and the pressing portion 42 are integrally formed.
  • the pressing portion 42 has a rod shape and is inserted into the outer cylinder 2 from the tip side.
  • the pressing portion 42 is connected to the bottom portion of the grip portion 41 at the base end portion. Further, the pressing portion 42 is in contact with the gasket 3 in an unused state. Therefore, when the pusher 4 is moved toward the distal end side with respect to the outer cylinder 2, the pressing portion 42 presses the gasket, and the gasket 3 moves toward the distal end side of the outer cylinder 2.
  • the pressing portion 42 may be separated from the gasket in an unused state, or the pressing portion 42 may be connected to the gasket 3. However, it is preferable that the pressing portion 42 is not connected to the gasket 3. As a result, after the gasket 3 is moved to the distal end side by the pusher 4, the gasket 3 cannot be moved to the proximal end side even if the pusher 4 is moved to the proximal end side. Use (refilling of the chemical solution 100) is prevented, and the safety of the syringe 1 is improved.
  • the gripping portion 41 has a bottomed cylindrical shape having a bottom portion, and covers the entire circumferential direction of the outer tube 2 and the contact portion 5. By making the holding part 41 into such a shape, it becomes easy to hold the syringe 1 and the operability of the syringe 1 is improved.
  • At least one groove 411 is formed on the inner wall of the grip portion 41.
  • the groove 411 extends in the longitudinal direction of the syringe 1 and a part of the flange 27 is engaged therewith.
  • the groove 411 functions as a guide when the pusher 4 and the outer cylinder 2 slide, whereby the sliding becomes smooth.
  • the groove 411 also has a function of preventing the pusher 4 from rotating in the circumferential direction with respect to the outer cylinder 2.
  • the grip portion 41 is provided with a claw portion (engagement portion) 412 provided so as to protrude inside.
  • the claw portion 412 is in contact with the proximal end surface of the flange 27 of the outer cylinder 2 in the unused state, and thereby the movement of the pusher 4 to the distal end side with respect to the outer cylinder 2 in the unused state. It is regulated. That is, the claw portion 412 constitutes a movement restricting means 200 that restricts the movement of the pusher 4 toward the distal end side with respect to the outer cylinder 2.
  • such a claw portion 412 is a force that moves the pusher 4 toward the distal end side with respect to the outer cylinder 2 and has a force greater than a predetermined magnitude (second pressing force; an external force described later).
  • a predetermined magnitude second pressing force; an external force described later.
  • the external force G2 that can damage the claw portion 412 is set to be larger than the force that can deform the contact portion 5 (external force G1). That is, when the external force G1 acts on the syringe 1, the contact portion 5 is deformed so as to be crushed, but the claw portion 412 is not damaged.
  • the flange 27 In the unused state, the flange 27 is in contact with the tip of the groove 411 and is in contact with the claw portion 412. Thereby, in the unused state, the relative positional relationship between the outer cylinder 2 and the pusher 4 is kept constant. Therefore, these do not move carelessly and the safety and operability of the syringe 1 are improved.
  • the overall length and width (outer diameter) of the grip portion 41 are not particularly limited as long as the grip portion 41 can be gripped.
  • the holding part 41 may be comprised so that the outer cylinder 2 located inside can be visually recognized. Thereby, since the state of the chemical
  • a configuration is not particularly limited, and for example, a method of configuring the grip portion 41 with a transparent member can be mentioned.
  • grip part 41 is colored, the elongate window part extended in a longitudinal direction may be provided in these, and it may be made to visually recognize an inside through this window part.
  • the window part may be comprised with the transparent member and may be comprised with the through-hole.
  • the constituent material of the pusher 4 is not particularly limited, and for example, the same material as the constituent material of the outer cylinder 2 can be used.
  • the abutting portion 5 is brought into contact with a site (skin) to which the drug solution 100 such as an arm is administered, while holding the grasping portion 41.
  • the contact portion 5 is pressed against the skin with a predetermined strength. As a result, an external force G1 acts on the contact portion 5. Since the contact portion 5 is set to be deformed by the external force G1, when the external force G1 is applied, the contact portion 5 is deformed so that the opening of the storage portion 5a is expanded while being crushed. As a result, the epidermis around the site where the puncture needle 6 is punctured (hereinafter also simply referred to as “puncture site”) is pulled outward, that is, in a direction away from the puncture site, and tension is applied to the epidermis.
  • Puncture site the epidermis around the site where the puncture needle 6 is punctured
  • the projecting portion 512 moves to the tip side, and the tip portion presses the epidermis.
  • the epidermis inside the protruding portion 512 swells in a mountain shape, and the puncture needle 6 takes a posture substantially perpendicular to the epidermis.
  • the puncture needle 6 can be reliably punctured into the living body.
  • the protrusion part 512 presses an epidermis
  • the puncture needle 6 protrudes from the front-end
  • the positional relationship between the puncture needle 6 and the epidermis is regulated by the contact portion 5 and the mouth portion 22, whereby the needle tip reaches a predetermined depth. Thereby, it will be in a puncture state.
  • the puncture needle 6 can be punctured into the living body and the drug solution 100 can be administered simply by gripping the grasping portion 41 and pressing the syringe 1 against the living body. That is, according to the syringe 1, administration of the chemical solution 100 is completed in one step. Moreover, according to the syringe 1, since the chemical
  • the posture of the syringe 1 can be stabilized by bringing the contact portion 5 into contact with the epidermis before the puncture needle 6 is punctured. Therefore, the operability of the syringe 1 is improved.
  • the outer peripheral portion of the contact portion 5 of the present embodiment is divided into a plurality of divided pieces 53 by slits 52, and each divided piece 53 is independently deformed along the shape of the epidermis. Can be more stable.
  • the puncture needle 6 in order to puncture the living body with the puncture needle 6 in the operation [3], it is necessary to deform the contact portion 5. Therefore, the user must press the contact portion 5 against the skin with a certain large pressing force. When the contact portion 5 is pressed against the epidermis with such a force, the outer cylinder 2 moves to the tip side vigorously, and the puncture needle 6 is punctured into the living body vigorously. Therefore, the puncture needle 6 can be punctured into the living body more reliably.
  • the length of the puncture needle 6 (puncture depth) is as short as about 0.5 mm to 3.0 mm. Therefore, for example, when the puncture needle 6 is slowly punctured into the living body, there is a possibility that the puncture needle 6 may not be punctured into the living body simply because the epidermis is pressed by the puncture needle 6 and recessed.
  • the puncture needle 6 is punctured into the living body vigorously by the user's operation like the syringe 1
  • the above-described problems can be solved and the puncture needle 6 can be punctured into the living body reliably. .
  • the contact portion 5 is deformed so that the opening of the storage portion 5a is expanded while being crushed by the application of the external force G1.
  • the diameter of the opening of the storage portion 5a expands the epidermis around the puncture site, the sagging of the epidermis can be reduced, and the puncture needle 6 can be punctured more reliably. Can do.
  • the syringe 1 is configured such that the claw portion 412 is broken during the operation. Thereby, since the syringe 1 once used cannot be reused, the safety of the syringe 1 is improved.
  • FIG. 4 is a longitudinal sectional view showing a second embodiment of the syringe of the present invention.
  • the syringe of the present embodiment is the same as the syringe of the first embodiment except that the configuration of the contact portion is different.
  • each of the divided pieces 53 included in the contact portion 5A is formed with a fragile portion 54A that is thinner than other portions.
  • the fragile portion 54A is formed in the entire width direction of each divided piece 53. Further, each fragile portion 54 ⁇ / b> A is located closer to the proximal end than the distal end of the protruding portion 512.
  • the contact portion 5 having such a configuration is pressed against the skin by a force of a predetermined magnitude or more, and when the external force G1 described in the first embodiment is applied, the contact portion 5 is deformed so that the opening is expanded while being crushed.
  • the front end side is bent from the fragile portion 54A of each divided piece 53 so as to be broken.
  • the protruding portion 512 and the puncture needle 6 protrude from the storage portion 5a toward the distal end, the protruding portion 512 presses the epidermis, and the puncture needle 6 is punctured into the living body.
  • the puncture needle 6 can be punctured more reliably into the living body.
  • the distal end side in order to puncture the living body with the puncture needle 6, the distal end side must be bent from the fragile portion 54 ⁇ / b> A of each divided piece 53.
  • the user in order to puncture the living body with the puncture needle 6, the distal end side must be bent from the fragile portion 54 ⁇ / b> A of each divided piece 53.
  • the user must press the contact portion 5 against the skin with a large pressing force.
  • each divided piece 53 is bent at the fragile portion 54A, and the puncture needle 6 is moved to the tip side vigorously and punctured into the living body vigorously. Therefore, the puncture needle 6 can be punctured into the living body more reliably.
  • the contact portion 5 is configured to be broken by being bent at the fragile portion 54A. Therefore, since the syringe 1A once used cannot be reused, the safety of the syringe 1A is improved.
  • the syringe of the present invention may be a combination of any two or more configurations (features) of the above embodiments.
  • a syringe excellent in operability can be provided. Specifically, for example, when a gripping part is gripped and pressed against a living body, the abutting part first contacts the living body and the posture of the syringe is maintained. When the gripping part is further pressed against the living body, the puncture needle is pressed against the living body. When the puncture is performed and the grasping portion is further pressed against the living body, the drug solution is injected from the puncture needle into the living body. That is, the administration of the drug solution is completed in one step of pressing the grip portion against the living body.
  • the puncture needle can be punctured into the living body vigorously, for example, even when the puncture needle is short, the puncture needle can be reliably punctured into the living body. From the above, the syringe has excellent operability. Furthermore, by improving operability, administration errors can be prevented, and reliability and safety are also improved.

Abstract

A syringe (1) has an outer tube (2) on which a puncture needle (6) is disposed, a gasket (3) which can slide within the outer tube (2), a drug solution (100) stored within the outer tube (2), a contact part (5) which comes into contact with a living body prior to puncturing the living body with the puncture needle (6), a plunger(4) which moves the gasket (3) towards the tip end side, and a movement restricting means (200) for restricting the movement of the plunger (4) towards the tip end side of the outer tube (2). In the syringe (1) having said configuration, the contact part (5) deforms in a crushing manner when the plunger (4) is pressed against the living body at a first pressing force while the contact part (5) comes into contact with the living body.

Description

シリンジSyringe
　本発明は、シリンジに関する。 The present invention relates to a syringe.
　シリンジは、一般に、外筒と、この外筒内で摺動し得るガスケットと、このガスケットを移動操作するプランジャとで構成されている。また、外筒は、胴部と、胴部の先端側に設けられ、胴部に対して縮径した縮径部（口部）とを有している。このようなシリンジは、押し子を外筒内に押し込むことによりガスケットを先端側へ移動させ、それにより、外筒に収納された薬液を口部の開口から外筒外へ導くように構成されている（例えば、特許文献１参照）。 The syringe is generally composed of an outer cylinder, a gasket that can slide in the outer cylinder, and a plunger that moves the gasket. Moreover, the outer cylinder has a trunk | drum and the reduced diameter part (mouth part) which was provided in the front end side of the trunk | drum and diameter-reduced with respect to the trunk | drum. Such a syringe is configured to move the gasket toward the distal end side by pushing the pusher into the outer cylinder, thereby guiding the chemical stored in the outer cylinder to the outside of the outer cylinder from the opening of the mouth. (For example, refer to Patent Document 1).
　特許文献１に記載のシリンジは、例えば、次のように使用される。口部に穿刺針を接続した状態で、親指を除く４本の指で外筒を握るとともに親指を押し子に掛けた状態で穿刺針を皮膚に穿刺し、その状態を維持しつつ、親指で押し子を押し込むことによって薬液を投与する。また、口部に穿刺針を接続した状態で、人差し指と中指とで外筒を狭持するとともに親指を押し子に掛けた状態で穿刺針を皮膚に穿刺し、その状態を維持しつつ、親指で押し子を押し込むことによって薬液を投与する。 The syringe described in Patent Document 1 is used as follows, for example. With the puncture needle connected to the mouth, hold the outer tube with four fingers except the thumb, puncture the skin with the thumb on the pusher, and maintain the state with the thumb. The drug solution is administered by pushing the pusher. In addition, with the puncture needle connected to the mouth, the outer tube is held between the index finger and the middle finger, and the puncture needle is punctured into the skin with the thumb placed on the pusher, and the thumb is maintained while maintaining the state. The drug solution is administered by pushing the pusher in.
　しかしながら、このような使用方法では、穿刺針を皮膚に穿刺し、その状態を維持するステップと、皮膚に対する外筒の位置を維持しつつ外筒に対して押し子を押し込むステップとの２ステップによらなければ薬液を投与することができない。また、押し子を操作することによって外筒２を固定する力が弱くなり、針の穿刺深さが変化しまうおそれもある。以上のように、従来のシリンジでは、操作性が悪く、使用が困難であるとの問題がある。 However, in such a method of use, there are two steps: a step of puncturing the skin with a puncture needle and maintaining the state, and a step of pushing the pusher into the outer tube while maintaining the position of the outer tube with respect to the skin. If you don't, you won't be able to administer the drug solution. In addition, the force for fixing the outer cylinder 2 is weakened by operating the pusher, and the puncture depth of the needle may change. As described above, the conventional syringe has a problem that the operability is poor and the use is difficult.
　特に、インシュリンの投与等、患者が自ら薬剤を投与する場合（皮下注射等の場合）には、薬液の注入圧力が高いため、上述したような問題がさらに顕著となる。 In particular, when the patient administers the drug himself (in the case of subcutaneous injection or the like) such as insulin administration, the above-described problems become more prominent because the injection pressure of the drug solution is high.
特開２００４－９７６４０号公報JP 2004-97640 A
　本発明の目的は、操作性に優れるシリンジを提供することにある。 An object of the present invention is to provide a syringe with excellent operability.
　上記目的を達成するために、本発明は、先端側に口部を有する外筒と、
　前記口部に接続され、生体を穿刺可能な針先を有する穿刺針と、
　前記外筒内で摺動し得るガスケットと、
　前記外筒と前記ガスケットとで囲まれる空間に収納された薬液と、
　前記穿刺針を前記生体に穿刺するのに先立って前記生体に当接させる当接部と、
　前記外筒に対して該外筒の長手方向に移動可能に設けられ、前記ガスケットを前記外筒の先端側に移動操作する押し子と、
　前記押し子の前記外筒に対する先端側への移動を規制する移動規制手段とを有し、
　前記押し子は、前記外筒の外周の少なくとも一部を覆うとともに前記外筒に対して該外筒の長手方向に移動可能に設けられた筒状の把持部と、該把持部と連結するとともに前記外筒内に挿入され、前記把持部の前記外筒に対する先端側への移動によって前記ガスケットを先端側へ移動させる押圧部とを有し、
　前記当接部は、先端側に開口し、内側に前記穿刺針を収納する収納部を有し、
　前記当接部を前記生体に当接させた状態にて、前記押し子を第１の押圧力で前記生体に押し込むと、前記当接部が前記外筒の長手方向に潰れるように変形することにより前記収納部の前記開口から前記穿刺針が突出し、前記穿刺針が前記生体に穿刺された穿刺状態となり、
　前記穿刺状態から前記押し子を前記第１の押圧力よりも大きな第２の押圧力で前記生体に押し込むと、前記移動規制手段による規制が解除され、前記押し子が前記外筒に対して先端側へ移動し、これにより前記ガスケットが先端側へ移動し、前記穿刺針から前記生体内に薬液が注入されるように構成されていることを特徴とするシリンジである。 In order to achieve the above object, the present invention provides an outer cylinder having a mouth on the tip side,
A puncture needle connected to the mouth and having a needle tip capable of puncturing a living body;
A gasket that can slide in the outer cylinder;
A chemical solution stored in a space surrounded by the outer cylinder and the gasket;
An abutting portion that abuts the living body prior to puncturing the living body with the puncture needle;
A pusher which is provided so as to be movable in the longitudinal direction of the outer cylinder with respect to the outer cylinder, and which moves the gasket toward the distal end side of the outer cylinder;
Movement restricting means for restricting movement of the pusher toward the distal end side with respect to the outer cylinder,
The pusher covers at least a part of the outer periphery of the outer cylinder and is connected to the cylindrical gripping part provided to be movable in the longitudinal direction of the outer cylinder with respect to the outer cylinder. A pressing portion that is inserted into the outer cylinder and moves the gasket toward the distal end side by moving the gripping portion toward the distal end side with respect to the outer cylinder;
The contact portion has an accommodating portion that opens to the distal end side and accommodates the puncture needle inside.
When the pusher is pushed into the living body with the first pressing force in a state where the abutting part is in contact with the living body, the contacting part is deformed so as to be crushed in the longitudinal direction of the outer cylinder. The puncture needle protrudes from the opening of the storage portion, and the puncture needle is punctured into the living body.
When the pusher is pushed into the living body with a second pressing force larger than the first pressing force from the puncture state, the restriction by the movement restricting means is released, and the pusher is distal to the outer cylinder. The syringe is configured to move to the side, whereby the gasket moves to the distal end side, and the drug solution is injected into the living body from the puncture needle.
　本発明のシリンジでは、前記当接部は、ドーム型の基体と、前記基体の外周から中央部に向けて形成された複数のスリットとを有しているのが好ましい。 In the syringe of the present invention, it is preferable that the contact portion has a dome-shaped base and a plurality of slits formed from the outer periphery to the center of the base.
　本発明のシリンジでは、前記押し子を前記第１の押圧力で前記生体に押し込むと、前記当接部は、前記外筒の長手方向に潰れつつ、前記収納部の前記開口が拡径するように変形するのが好ましい。 In the syringe of the present invention, when the pusher is pushed into the living body with the first pressing force, the contact portion is crushed in the longitudinal direction of the outer cylinder, and the opening of the storage portion is expanded. It is preferable to deform it.
　本発明のシリンジでは、前記当接部は、前記スリットによって分割された複数の分割片と、前記分割片の延在方向の途中に設けられた脆弱部とを有しており、前記押し子を前記第１の押圧力で前記生体に押し込むと、前記分割片が前記脆弱部で折れ曲がるように変形するのが好ましい。 In the syringe of the present invention, the contact portion has a plurality of divided pieces divided by the slit, and a weakened portion provided in the middle of the extending direction of the divided pieces, and the pusher is It is preferable that when the first pressing force is pushed into the living body, the divided piece is deformed so as to be bent at the fragile portion.
　本発明のシリンジでは、前記当接部は、前記分割片が前記脆弱部で折れ曲がることによって破損するのが好ましい。 In the syringe of the present invention, it is preferable that the abutting portion is broken when the divided piece is bent at the weakened portion.
　本発明のシリンジでは、前記当接部は、前記収納部内に突出し、前記穿刺針の周囲を囲むように設けられた突出部を有し、
　前記突出部は、前記第１の押圧力によって前記当接部が変形した状態で、前記生体を押圧するのが好ましい。 In the syringe of the present invention, the contact portion protrudes into the storage portion, and has a protruding portion provided to surround the puncture needle,
The protrusion preferably presses the living body in a state where the contact portion is deformed by the first pressing force.
　本発明のシリンジでは、前記移動規制手段は、前記第２の押圧力によって破損するよう構成されているのが好ましい。 In the syringe of the present invention, it is preferable that the movement restricting means is configured to be damaged by the second pressing force.
図１は、本発明のシリンジの第１実施形態を示す縦断面図である。FIG. 1 is a longitudinal sectional view showing a first embodiment of the syringe of the present invention. 図２は、図１に示すシリンジが有する当接部の斜視図である。FIG. 2 is a perspective view of a contact portion of the syringe shown in FIG. 図３は、図１に示すシリンジの使用方法の一例を説明する模式図である。FIG. 3 is a schematic diagram illustrating an example of a method of using the syringe shown in FIG. 図４は、本発明のシリンジの第２実施形態を示す縦断面図である。FIG. 4 is a longitudinal sectional view showing a second embodiment of the syringe of the present invention.
　以下、本発明のシリンジを添付図面に示す好適な実施形態に基づいて詳細に説明する。 Hereinafter, the syringe of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings.
　＜第１実施形態＞
　まず、本発明のシリンジの第１実施形態について説明する。 <First Embodiment>
First, a first embodiment of the syringe of the present invention will be described.
　図１は、本発明のシリンジの第１実施形態を示す縦断面図、図２は、図１に示すシリンジが有する当接部の斜視図、図３は、図１に示すシリンジの使用方法の一例を説明する模式図である。なお、以下では、説明の都合上、図１および図３中の上側を「基端」、下側を「先端」という。また、説明の便宜上、シリンジを使用しておらず、かつシリンジに外力が加わっていない状態、すなわち図１に示す状態を「未使用状態」とも言う。 1 is a longitudinal sectional view showing a first embodiment of the syringe of the present invention, FIG. 2 is a perspective view of an abutting portion of the syringe shown in FIG. 1, and FIG. 3 is a method of using the syringe shown in FIG. It is a schematic diagram explaining an example. In the following, for convenience of explanation, the upper side in FIGS. 1 and 3 is referred to as a “base end” and the lower side is referred to as a “tip”. In addition, for convenience of explanation, the state where no syringe is used and no external force is applied to the syringe, that is, the state shown in FIG. 1 is also referred to as “unused state”.
　本実施形態では、薬液１００を表皮と真皮の間に投与する「皮内注射」に用いられるシリンジについて代表して説明するが、本発明のシリンジの用途は、これに限定されず、例えば、薬液１００を皮下組織に投与する「皮下注射」や、薬液１００を筋肉内に投与する「筋肉注射」に適用してもよい。 In the present embodiment, a syringe used for “intradermal injection” in which the drug solution 100 is administered between the epidermis and the dermis will be described as a representative. However, the use of the syringe of the present invention is not limited to this, and for example, a drug solution You may apply to "subcutaneous injection" which administers 100 to subcutaneous tissue, and "muscular injection" which administers the chemical | medical solution 100 intramuscularly.
　図１に示すシリンジ１は、内部に予め薬液１００が収納されたプレフィルドシリンジである。このようなシリンジ１は、外筒２と、外筒２の設けられた穿刺針６と、外筒２内で摺動し得るガスケット３と、ガスケット３を移動操作する押し子４と、穿刺針６を穿刺するのに先立って皮膚に当接させる当接部５と、当接部５に対して外筒２を付勢するバネ部材（付勢手段）９とを備えている。 A syringe 1 shown in FIG. 1 is a prefilled syringe in which a chemical solution 100 is stored in advance. Such a syringe 1 includes an outer cylinder 2, a puncture needle 6 provided with the outer cylinder 2, a gasket 3 that can slide in the outer cylinder 2, a pusher 4 that moves the gasket 3, and a puncture needle. Prior to puncturing 6, a contact portion 5 that contacts the skin and a spring member (biasing means) 9 that biases the outer cylinder 2 against the contact portion 5 are provided.
　このシリンジ１では、外筒２とガスケット３とで囲まれる空間であって、ガスケット３の先端側に位置する空間１１内に、予め液状の薬液１００が収納されている。薬液１００としては、特に限定されないが、例えば、ビタミン剤（総合ビタミン剤）、各種アミノ酸、ヘパリンのような抗血栓剤、インシュリン、抗生物質、抗腫瘍剤、鎮痛剤、強心剤、静注麻酔剤、抗パーキンソン剤、潰瘍治療剤、副腎皮質ホルモン剤、不整脈用剤、補正電解質、タンパク分解酵素阻害剤、トロンボキサン合成阻害剤等が挙げられる。 In this syringe 1, a liquid chemical solution 100 is stored in advance in a space 11 surrounded by the outer cylinder 2 and the gasket 3, which is located on the tip side of the gasket 3. Although it does not specifically limit as the chemical | medical solution 100, For example, a vitamin agent (total vitamin agent), various amino acids, antithrombotic agents like heparin, insulin, antibiotics, an antitumor agent, an analgesic agent, a cardiotonic agent, an intravenous anesthetic agent, Antiparkinson agents, ulcer treatment agents, corticosteroid agents, arrhythmia agents, correction electrolytes, protease inhibitors, thromboxane synthesis inhibitors and the like can be mentioned.
　なお、前記空間に収納される薬液１００の量は、特に限定されないが、例えば、０．０２～２．０ｍＬ程度である。 The amount of the chemical solution 100 stored in the space is not particularly limited, but is about 0.02 to 2.0 mL, for example.
　以下、シリンジ１の各部について順次詳細に説明する。 Hereinafter, each part of the syringe 1 will be described in detail sequentially.
　－外筒－
　外筒２は、有底筒状の部材で構成されている。図１に示すように、外筒２は、底部２１１を有する胴部２１と、胴部２１の基端外周に設けられた板状のフランジ２７と、底部２１１の中央部に設けられ、胴部２１に対し縮径した口部２２とを有しており、これらが一体的に形成されている。 -Outer cylinder-
The outer cylinder 2 is composed of a bottomed cylindrical member. As shown in FIG. 1, the outer cylinder 2 includes a barrel portion 21 having a bottom portion 211, a plate-like flange 27 provided on the outer periphery of the proximal end of the barrel portion 21, and a central portion of the bottom portion 211. 21 and a mouth portion 22 having a reduced diameter with respect to 21, and these are integrally formed.
　外筒２の構成材料としては、例えば、ポリ塩化ビニル、ポリエチレン、ポリプロピレン、環状ポリオレフィン、ポリスチレン、ポリ－（４－メチルペンテン－１）、ポリカーボネート、アクリル樹脂、アクリルニトリル－ブタジエン－スチレン共重合体、ポリエチレンテレフタレート、ポリエチレンナフタレート等のポリエステル、ブタジエン－スチレン共重合体、ポリアミド（例えば、ナイロン６、ナイロン６・６、ナイロン６・１０、ナイロン１２）のような各種樹脂が挙げられるが、その中でも、成形が容易であるという点で、ポリプロピレン、環状ポリオレフィン、ポリエステル、ポリ－（４－メチルペンテン－１）のような樹脂が好ましい。 Examples of the constituent material of the outer cylinder 2 include polyvinyl chloride, polyethylene, polypropylene, cyclic polyolefin, polystyrene, poly- (4-methylpentene-1), polycarbonate, acrylic resin, acrylonitrile-butadiene-styrene copolymer, Various resins such as polyesters such as polyethylene terephthalate and polyethylene naphthalate, butadiene-styrene copolymers, and polyamides (for example, nylon 6, nylon 6,6, nylon 6,10, nylon 12) can be mentioned. Resin such as polypropylene, cyclic polyolefin, polyester, and poly- (4-methylpentene-1) is preferable because it is easy to mold.
　なお、外筒２は、内部の視認性を確保するために、実質的に透明であるのが好ましい。 In addition, it is preferable that the outer cylinder 2 is substantially transparent in order to ensure internal visibility.
　－穿刺針－
　穿刺針６は、外筒の口部２２に設けられており、その針先が口部２２から先端側に突出している。この穿刺針６は、生体を穿刺可能な針先を有しており、この針先を生体に穿刺することにより外筒２に収納された薬液１００を生体内に注入（投与）することができる。 -Puncture needle-
The puncture needle 6 is provided at the mouth portion 22 of the outer cylinder, and the needle tip projects from the mouth portion 22 toward the distal end side. The puncture needle 6 has a needle tip that can puncture a living body, and the medical solution 100 stored in the outer cylinder 2 can be injected (administered) into the living body by puncturing the living body with the needle tip. .
　このような穿刺針６としては、ＩＳＯの医療用針管の基準（ＩＳＯ９６２６：１９９１／Ａｍｄ．１：２００１（Ｅ））で２６～３３Ｇのサイズ（外径：０．２～０．４５ｍｍ）のものを使用することが好ましく、３０～３３Ｇのサイズのものを使用することがより好ましい。 The puncture needle 6 has a size of 26 to 33 G (outer diameter: 0.2 to 0.45 mm) based on the ISO medical needle tube standard (ISO9626: 1991 / Amd.1: 2001 (E)). Is preferably used, and more preferably 30 to 33G in size.
　また、穿刺針６の口部２２から突出している部分の長さ、すなわち生体内に穿刺される深さ（穿刺深さ）は、特に限定されないが、０．５ｍｍ～３．０ｍｍの範囲内に設定されることが好ましい。表皮の厚さは、概ね０．５～３．０ｍｍであるので、穿刺深さを上記範囲に設定することにより、シリンジ１が皮内注射により適した構成となる。 Further, the length of the portion of the puncture needle 6 protruding from the mouth portion 22, that is, the depth of puncture into the living body (puncture depth) is not particularly limited, but is within the range of 0.5 mm to 3.0 mm. It is preferably set. Since the thickness of the epidermis is approximately 0.5 to 3.0 mm, setting the puncture depth within the above range makes the syringe 1 more suitable for intradermal injection.
　また、穿刺針６の構成材料としては、特に限定されず、例えば、ステンレス鋼、アルミニウムまたはアルミニウム合金、チタンまたはチタン合金、Ｎｉ－Ｔｉ合金等の超弾性合金等の各種金属材料、ポリフェニレンサルファイド等の各種硬質樹脂材料等が挙げられる。 The constituent material of the puncture needle 6 is not particularly limited. For example, various metal materials such as stainless steel, aluminum or an aluminum alloy, titanium or a titanium alloy, a superelastic alloy such as a Ni—Ti alloy, polyphenylene sulfide, and the like. Various hard resin materials are mentioned.
　図１に示すように、穿刺針６は、キャップ７で覆われている。これにより、穿刺針６が保護されるとともに、穿刺針６の誤穿刺を防止することができる。このキャップ７は、シリンジ１を使用する際に取り外して用いられる。取り外し易さを考慮すると、キャップ７は、当接部５の先端から突出する形状となっているのが好ましい。 As shown in FIG. 1, the puncture needle 6 is covered with a cap 7. Thereby, the puncture needle 6 is protected and erroneous puncture of the puncture needle 6 can be prevented. The cap 7 is used by being removed when the syringe 1 is used. Considering ease of removal, it is preferable that the cap 7 has a shape protruding from the tip of the contact portion 5.
　－ガスケット－
　外筒２内には、弾性材料で構成されたガスケット３が収納されている。ガスケット３の外周部には、複数のリング状の突部が全周にわたって形成されており、この突部が外筒２の内周面に対し密着しつつ摺動することにより、液密性をより確実に保持するとともに、摺動性の向上が図れる。 -gasket-
A gasket 3 made of an elastic material is accommodated in the outer cylinder 2. A plurality of ring-shaped protrusions are formed on the entire outer periphery of the gasket 3, and the protrusions slide while being in close contact with the inner peripheral surface of the outer cylinder 2. While holding more reliably, slidability can be improved.
　ガスケット３の構成材料としては、特に限定されず、例えば、天然ゴム、ブチルゴム、イソプレンゴム、ブタジエンゴム、スチレン－ブタジエンゴム、シリコーンゴムのような各種ゴム材料や、ポリウレタン系、ポリエステル系、ポリアミド系、オレフィン系、スチレン系等の各種熱可塑性エラストマー、あるいはそれらの混合物等の弾性材料が挙げられる。 The constituent material of the gasket 3 is not particularly limited. For example, various rubber materials such as natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, silicone rubber, polyurethane, polyester, polyamide, Examples thereof include elastic materials such as various thermoplastic elastomers such as olefins and styrenes, or mixtures thereof.
　－当接部－
　当接部５は、シリンジ１を使用する際に、穿刺針６の穿刺に先立って表皮（生体）に当接させ、シリンジ１の姿勢を安定させる機能を有する。 -Contact part-
The contact portion 5 has a function of stabilizing the posture of the syringe 1 by bringing it into contact with the epidermis (living body) prior to the puncture of the puncture needle 6 when using the syringe 1.
　図１に示すように、このような当接部５は、外筒２の口部２２に固定されている。また、当接部５は、先端側に向けて湾曲したドーム型（傘状）をなし、弾性変形可能に構成されている。また、当接部５は、その内側に先端側に開放する凹部で構成された収納部５ａを有しており、収納部５ａに穿刺針６が収納されている。 As shown in FIG. 1, such a contact portion 5 is fixed to the mouth portion 22 of the outer cylinder 2. Further, the contact portion 5 has a dome shape (umbrella shape) curved toward the distal end side, and is configured to be elastically deformable. Moreover, the contact part 5 has the accommodating part 5a comprised by the recessed part open | released to the front end side at the inner side, and the puncture needle 6 is accommodated in the accommodating part 5a.
　このような形状とすることによりに、当接部５を、穿刺針６を穿刺する部位の周囲ほぼ全周にわたって当接させることができる。そのため、シリンジ１の姿勢が安定し、かつ穿刺針６を表皮に対してほぼ垂直な姿勢に保つことができる。 By adopting such a shape, the contact portion 5 can be brought into contact with the entire periphery of the portion where the puncture needle 6 is punctured. Therefore, the posture of the syringe 1 is stable, and the puncture needle 6 can be maintained in a posture substantially perpendicular to the epidermis.
　未使用状態における収納部５ａの高さＬは、穿刺針６を収納することができれば、特に限定されないが、穿刺針６を穿刺するのに先立って、当接部５が適切な押圧力で表皮を押圧し、穿刺針６が確実に穿刺されるように設定される。具体的には、高さＬは、収納部５ａの開口径に応じて適宜設定され、例えば、開口径が１０ｍｍ程度の場合には、０．７５ｍｍ～２．６ｍｍの範囲内に設定するのが好ましい。 The height L of the storage portion 5a in the unused state is not particularly limited as long as the puncture needle 6 can be stored, but before the puncture needle 6 is punctured, the contact portion 5 is applied with an appropriate pressing force by the epidermis. Is set so that the puncture needle 6 is punctured securely. Specifically, the height L is appropriately set according to the opening diameter of the storage portion 5a. For example, when the opening diameter is about 10 mm, the height L is set within a range of 0.75 mm to 2.6 mm. preferable.
　図１および図２に示すように、このような当接部５は、ドーム型の基体５１と、基体５１の外周から中央部に向けて放射状に形成された複数のスリット（切り込み）５２とを有している。すなわち、基体５１の外周部には、スリット５２によって分割され、先端が自由端である複数の分割片５３が形成されている。 As shown in FIGS. 1 and 2, such a contact portion 5 includes a dome-shaped base 51 and a plurality of slits (cuts) 52 formed radially from the outer periphery of the base 51 toward the center. Have. That is, a plurality of divided pieces 53 that are divided by the slits 52 and that have free ends are formed on the outer peripheral portion of the base 51.
　基体５１の中央部には、貫通孔５１１が形成されており、貫通孔５１１に外筒２の口部２２が嵌入されている。これにより、当接部５が外筒２に固定される。なお、当接部５と口部２２との固定方法は、特に限定されず、例えば、螺合によって固定されていてもよい。 A through hole 511 is formed at the center of the base 51, and the mouth portion 22 of the outer cylinder 2 is fitted into the through hole 511. Thereby, the contact part 5 is fixed to the outer cylinder 2. In addition, the fixing method of the contact part 5 and the opening | mouth part 22 is not specifically limited, For example, you may fix by screwing.
　スリット５２は、当接部５を変形し易くするために形成されている。スリット５２の数としては、当接部５の大きさ等によっても異なるが、例えば、４本～１６本程度であるのが好ましい。 The slit 52 is formed to facilitate the deformation of the contact portion 5. The number of slits 52 varies depending on the size of the contact portion 5 and the like, but is preferably about 4 to 16, for example.
　また、基体５１は、収納部５ａ内に突出する突出部５１２を有している。突出部５１２は、口部２２を中心とする略円環状に形成されているが、スリット５２によって複数に分割されている。未使用状態では、各突出部５１２の先端は、収納部５ａの開口よりも基端側に位置している。また、複数の突出部５１２で囲まれる領域内に穿刺針６の先端が位置している。 Further, the base 51 has a protruding portion 512 that protrudes into the storage portion 5a. The protruding portion 512 is formed in a substantially annular shape centering on the mouth portion 22, but is divided into a plurality of portions by the slit 52. In the unused state, the distal end of each projecting portion 512 is located closer to the proximal end than the opening of the storage portion 5a. In addition, the tip of puncture needle 6 is located in a region surrounded by a plurality of protrusions 512.
　このような当接部５は、後述するように、所定の大きさ以上の力（第１の押圧力；後述する外力Ｇ１）によって表皮に押し付けられると、その方向に潰れつつ、収納部５ａの開口径が拡径するように変形する。そして、当接部５がこのように変形すると、収納部５ａに収納されていた穿刺針６が収納部５ａの開口から突出し、穿刺針６が生体に穿刺される。 As will be described later, when the contact portion 5 is pressed against the outer skin by a force (first pressing force; external force G1 described later) having a predetermined magnitude or more, the contact portion 5 is crushed in that direction, The opening diameter is deformed so as to increase. And when the contact part 5 deform | transforms in this way, the puncture needle 6 accommodated in the accommodating part 5a will protrude from the opening of the accommodating part 5a, and the puncture needle 6 will puncture a biological body.
　当接部５の構成材料としては、弾性変形可能に構成することができれば特に限定されず、例えば、外筒２の構成材料と同様の材料を用いることができる。 The constituent material of the contact portion 5 is not particularly limited as long as it can be elastically deformed. For example, the same material as the constituent material of the outer cylinder 2 can be used.
　－押し子－
　押し子４は、外筒２に対して、外筒２の長手方向に移動可能に設けられている。図１に示すように、押し子４は、使用者が把持する把持部４１と、ガスケット３を押圧する押圧部４２とを有している。本実施形態では、把持部４１と押圧部４２とが一体的に形成されている。 -Pusher-
The pusher 4 is provided so as to be movable in the longitudinal direction of the outer cylinder 2 with respect to the outer cylinder 2. As shown in FIG. 1, the pusher 4 includes a grip portion 41 that is gripped by the user and a pressing portion 42 that presses the gasket 3. In the present embodiment, the grip portion 41 and the pressing portion 42 are integrally formed.
　押圧部４２は、棒状をなし、その先端側から外筒２内に挿入されている。また、押圧部４２は、その基端部にて把持部４１の底部と連結している。また、押圧部４２は、未使用状態にてガスケット３に当接している。そのため、押し子４を外筒２に対して先端側へ移動させると、押圧部４２がガスケットを押圧し、ガスケット３が外筒２の先端側へ移動する。 The pressing portion 42 has a rod shape and is inserted into the outer cylinder 2 from the tip side. The pressing portion 42 is connected to the bottom portion of the grip portion 41 at the base end portion. Further, the pressing portion 42 is in contact with the gasket 3 in an unused state. Therefore, when the pusher 4 is moved toward the distal end side with respect to the outer cylinder 2, the pressing portion 42 presses the gasket, and the gasket 3 moves toward the distal end side of the outer cylinder 2.
　なお、シリンジ１では、未使用状態にて、押圧部４２がガスケットから離間していてもよいし、また、押圧部４２がガスケット３と連結していてもよい。ただし、押圧部４２は、ガスケット３と連結していないのが好ましい。これにより、押し子４によって、ガスケット３を先端側に移動させた後は、押し子４を基端側に移動させてもガスケット３を基端側に移動させることができないため、シリンジ１の再利用（薬液１００の再充填）が防止され、シリンジ１の安全性が向上する。 In the syringe 1, the pressing portion 42 may be separated from the gasket in an unused state, or the pressing portion 42 may be connected to the gasket 3. However, it is preferable that the pressing portion 42 is not connected to the gasket 3. As a result, after the gasket 3 is moved to the distal end side by the pusher 4, the gasket 3 cannot be moved to the proximal end side even if the pusher 4 is moved to the proximal end side. Use (refilling of the chemical solution 100) is prevented, and the safety of the syringe 1 is improved.
　把持部４１は、底部を有する有底筒状をなし、外筒２および当接部５の周方向の全域を覆っている。把持部４１をこのような形状とすることにより、シリンジ１を把持し易くなり、シリンジ１の操作性が向上する。 The gripping portion 41 has a bottomed cylindrical shape having a bottom portion, and covers the entire circumferential direction of the outer tube 2 and the contact portion 5. By making the holding part 41 into such a shape, it becomes easy to hold the syringe 1 and the operability of the syringe 1 is improved.
　把持部４１の内壁には、少なくとも１つの溝４１１が形成されている。溝４１１は、シリンジ１の長手方向に延在しており、フランジ２７の一部が係合している。この溝４１１は、押し子４と外筒２とが摺動する際のガイドとして機能し、これにより、前記摺動が円滑となる。また、溝４１１は、押し子４が外筒２に対してその周方向に回転するのを防止する機能も有している。 At least one groove 411 is formed on the inner wall of the grip portion 41. The groove 411 extends in the longitudinal direction of the syringe 1 and a part of the flange 27 is engaged therewith. The groove 411 functions as a guide when the pusher 4 and the outer cylinder 2 slide, whereby the sliding becomes smooth. The groove 411 also has a function of preventing the pusher 4 from rotating in the circumferential direction with respect to the outer cylinder 2.
　また、把持部４１には、その内側に突出して設けられたツメ部（係合部）４１２が設けられている。シリンジ１では、未使用状態にて、ツメ部４１２が外筒２のフランジ２７の基端面と当接しており、これにより、未使用状態における押し子４の外筒２に対する先端側への移動が規制されている。すなわち、ツメ部４１２は、押し子４の外筒２に対する先端側への移動を規制する移動規制手段２００を構成している。 Further, the grip portion 41 is provided with a claw portion (engagement portion) 412 provided so as to protrude inside. In the syringe 1, the claw portion 412 is in contact with the proximal end surface of the flange 27 of the outer cylinder 2 in the unused state, and thereby the movement of the pusher 4 to the distal end side with respect to the outer cylinder 2 in the unused state. It is regulated. That is, the claw portion 412 constitutes a movement restricting means 200 that restricts the movement of the pusher 4 toward the distal end side with respect to the outer cylinder 2.
　このようなツメ部４１２は、後述するように、押し子４を外筒２に対して先端側へ移動させる力であって、所定の大きさ以上の力（第２の押圧力；後述する外力Ｇ２）が加わると、折れ曲がって破損する構造となっており、ツメ部４１２が破損することにより、前記規制が解除され、押し子４の外筒２に対する先端側への移動が可能となる。 As will be described later, such a claw portion 412 is a force that moves the pusher 4 toward the distal end side with respect to the outer cylinder 2 and has a force greater than a predetermined magnitude (second pressing force; an external force described later). When G2) is added, the structure is bent and broken. When the claw portion 412 is broken, the restriction is released, and the pusher 4 can be moved toward the distal end side with respect to the outer cylinder 2.
　なお、ツメ部４１２を破損させることのできる外力Ｇ２は、当接部５を変形させることのできる力（外力Ｇ１）よりも大きく設定されている。すなわち、シリンジ１に外力Ｇ１が作用すると、当接部５は、潰れるようにして変形するが、ツメ部４１２は、破損しない。 In addition, the external force G2 that can damage the claw portion 412 is set to be larger than the force that can deform the contact portion 5 (external force G1). That is, when the external force G1 acts on the syringe 1, the contact portion 5 is deformed so as to be crushed, but the claw portion 412 is not damaged.
　また、未使用状態では、フランジ２７が溝４１１の先端と当接するとともに、ツメ部４１２と当接している。これにより、未使用状態では、外筒２と押し子４の相対的位置関係を一定に維持されている。そのため、これらが不用意に移動することがなく、シリンジ１の安全性および操作性が向上する。 In the unused state, the flange 27 is in contact with the tip of the groove 411 and is in contact with the claw portion 412. Thereby, in the unused state, the relative positional relationship between the outer cylinder 2 and the pusher 4 is kept constant. Therefore, these do not move carelessly and the safety and operability of the syringe 1 are improved.
　なお、把持部４１の全長や幅（外径）は、把持できれば、特に限定されない。 Note that the overall length and width (outer diameter) of the grip portion 41 are not particularly limited as long as the grip portion 41 can be gripped.
　また、把持部４１は、内部に位置する外筒２を視認できるように構成されていてもよい。これにより、外筒２に収容された薬液１００の状態や、ガスケット３の動きを視覚的に確認することができるため、シリンジ１の操作性および安全性が向上する。このような構成としては、特に限定されないが、例えば、把持部４１を透明な部材で構成する方法が挙げられる。また、把持部４１が着色されている場合には、これらに長手方向に延在する長尺状の窓部を設け、この窓部を介して内部を視認できるようにしてもよい。窓部は、透明な部材で構成されていてもよいし、貫通孔で構成されていてもよい。 Moreover, the holding part 41 may be comprised so that the outer cylinder 2 located inside can be visually recognized. Thereby, since the state of the chemical | medical solution 100 accommodated in the outer cylinder 2 and the motion of the gasket 3 can be confirmed visually, the operativity and safety | security of the syringe 1 improve. Such a configuration is not particularly limited, and for example, a method of configuring the grip portion 41 with a transparent member can be mentioned. Moreover, when the holding | grip part 41 is colored, the elongate window part extended in a longitudinal direction may be provided in these, and it may be made to visually recognize an inside through this window part. The window part may be comprised with the transparent member and may be comprised with the through-hole.
　このような押し子４の構成材料は、特に限定されず、例えば、外筒２の構成材料と同様の材料を用いることができる。 The constituent material of the pusher 4 is not particularly limited, and for example, the same material as the constituent material of the outer cylinder 2 can be used.
　以上、シリンジ１の構成について詳細に説明した。 The configuration of the syringe 1 has been described in detail above.
　次いで、シリンジ１の使用方法の一例について、図３に基づいて説明する。 Next, an example of how to use the syringe 1 will be described with reference to FIG.
　［１］　まず、未使用状態のシリンジ１を用意し、キャップ７を取り外す。 [1] First, an unused syringe 1 is prepared, and the cap 7 is removed.
　［２］　次いで、図３（ａ）に示すように、把持部４１を把持しながら、当接部５を例えば腕等の薬液１００を投与する部位（表皮）に当接させる。 [2] Next, as shown in FIG. 3A, the abutting portion 5 is brought into contact with a site (skin) to which the drug solution 100 such as an arm is administered, while holding the grasping portion 41.
　［３］　次いで、把持部４１を把持しながら、当接部５を表皮に所定の強さで押し付ける。これにより、当接部５に外力Ｇ１が作用する。当接部５は、外力Ｇ１によって変形するように設定されているため、外力Ｇ１が作用すると、当接部５は、潰れつつ収納部５ａの開口が拡径するように変形する。これにより、穿刺針６を穿刺する部位（以下、単に「穿刺部位」とも言う。）の周囲の表皮が外側、すなわち穿刺部位から離間する方向に引っ張られ、表皮に張力が作用した状態となる。 [3] Next, while gripping the grip portion 41, the contact portion 5 is pressed against the skin with a predetermined strength. As a result, an external force G1 acts on the contact portion 5. Since the contact portion 5 is set to be deformed by the external force G1, when the external force G1 is applied, the contact portion 5 is deformed so that the opening of the storage portion 5a is expanded while being crushed. As a result, the epidermis around the site where the puncture needle 6 is punctured (hereinafter also simply referred to as “puncture site”) is pulled outward, that is, in a direction away from the puncture site, and tension is applied to the epidermis.
　当接部５が上記のように変形すると、図３（ｂ）に示すように、突出部５１２が先端側に移動し、その先端部が表皮を押し付ける。これにより、突出部５１２の内側の表皮が山状に盛り上がるとともに、穿刺針６が表皮に対してほぼ垂直な姿勢となる。このような姿勢とすることにより、穿刺針６の生体への穿刺を確実に行うことができる。また、突出部５１２が表皮を押し付けるとともに、穿刺針６が収納部５ａの開口を介して当接部５の先端から突出し、穿刺針６の針先が生体に穿刺される。この際、当接部５および口部２２により、穿刺針６と表皮との位置関係が規制されることによって、針先が所定深さに到達する。これにより、穿刺状態となる。 When the contact portion 5 is deformed as described above, as shown in FIG. 3B, the projecting portion 512 moves to the tip side, and the tip portion presses the epidermis. As a result, the epidermis inside the protruding portion 512 swells in a mountain shape, and the puncture needle 6 takes a posture substantially perpendicular to the epidermis. By adopting such a posture, the puncture needle 6 can be reliably punctured into the living body. Moreover, while the protrusion part 512 presses an epidermis, the puncture needle 6 protrudes from the front-end | tip of the contact part 5 through opening of the accommodating part 5a, and the needle tip of the puncture needle 6 is punctured by the biological body. At this time, the positional relationship between the puncture needle 6 and the epidermis is regulated by the contact portion 5 and the mouth portion 22, whereby the needle tip reaches a predetermined depth. Thereby, it will be in a puncture state.
　なお、外力Ｇ１によっては、ツメ部４１２が破損しないため、この操作では、外筒２と押し子４の相対的位置関係が未使用状態のまま維持される。そのため、穿刺針６が生体に刺さりきる前に薬液１００が穿刺針６から排出されるのを防止することができ、シリンジ１の操作性および安全性が向上する。 In addition, since the nail | claw part 412 is not damaged depending on the external force G1, in this operation, the relative positional relationship between the outer cylinder 2 and the pusher 4 is maintained in an unused state. Therefore, it is possible to prevent the drug solution 100 from being discharged from the puncture needle 6 before the puncture needle 6 is completely inserted into the living body, and the operability and safety of the syringe 1 are improved.
　［４］　次いで、把持部４１をさらに強い力で生体へ押し付ける。これにより、当接部５を介して外筒２に外力Ｇ１と同じ方向でかつ外力Ｇ１よりも大きい外力Ｇ２が作用する。外力Ｇ２が作用すると、図３（ｃ）に示すように、ツメ部４１２が破損するとともに押し子４が外筒２に対して先端側へ移動し、これに伴って、押圧部４２によってガスケット３が押圧され、ガスケット３が先端側へ移動する。これにより、外筒２に収納された薬液１００が穿刺針６の針先から生体内へ注入される。 [4] Next, the grip portion 41 is pressed against the living body with a stronger force. As a result, an external force G2 in the same direction as the external force G1 and larger than the external force G1 acts on the outer cylinder 2 via the contact portion 5. When the external force G2 is applied, as shown in FIG. 3C, the claw portion 412 is broken and the pusher 4 moves toward the distal end side with respect to the outer cylinder 2, and accordingly, the gasket 3 is pressed by the pressing portion 42. Is pressed, and the gasket 3 moves to the tip side. Thereby, the chemical | medical solution 100 accommodated in the outer cylinder 2 is inject | poured in the living body from the needle tip of the puncture needle 6. FIG.
　以上、シリンジ１の使用方法の一例を説明した。 In the above, an example of how to use the syringe 1 has been described.
　このようなシリンジ１によれば、把持部４１を把持して、シリンジ１を生体に押し付ける操作だけで、穿刺針６の生体への穿刺と薬液１００の投与とを行うことができる。すなわち、シリンジ１によれば、１つのステップで薬液１００の投与が完了する。また、シリンジ１によれば、腕の力を利用して薬液１００を皮内に注入することができるため、充分な力でシリンジの操作を行うことができる。 According to such a syringe 1, the puncture needle 6 can be punctured into the living body and the drug solution 100 can be administered simply by gripping the grasping portion 41 and pressing the syringe 1 against the living body. That is, according to the syringe 1, administration of the chemical solution 100 is completed in one step. Moreover, according to the syringe 1, since the chemical | medical solution 100 can be inject | poured into skin using the force of an arm, operation of a syringe can be performed with sufficient force.
　また、シリンジ１によれば、穿刺針６を穿刺するのに先立って当接部５を表皮に当接させることにより、シリンジ１の姿勢を安定させることができる。そのため、シリンジ１の操作性が向上する。特に、本実施形態の当接部５は、その外周部がスリット５２によって複数の分割片５３に分割されており、各分割片５３が表皮の形状に沿って独立して変形するため、シリンジ１の姿勢をより安定させることができる。 Further, according to the syringe 1, the posture of the syringe 1 can be stabilized by bringing the contact portion 5 into contact with the epidermis before the puncture needle 6 is punctured. Therefore, the operability of the syringe 1 is improved. In particular, the outer peripheral portion of the contact portion 5 of the present embodiment is divided into a plurality of divided pieces 53 by slits 52, and each divided piece 53 is independently deformed along the shape of the epidermis. Can be more stable.
　また、前述したように、操作［３］にて、穿刺針６を生体に穿刺するには、当接部５を変形させる必要がある。そのため、使用者は、ある程度大きな押圧力で当接部５を表皮に押し付けなければならない。そのような力で当接部５を表皮に押し付けると、外筒２が勢いよく先端側へ移動し、穿刺針６が勢いよく生体に穿刺される。そのため、穿刺針６をより確実に生体に穿刺することができる。 Further, as described above, in order to puncture the living body with the puncture needle 6 in the operation [3], it is necessary to deform the contact portion 5. Therefore, the user must press the contact portion 5 against the skin with a certain large pressing force. When the contact portion 5 is pressed against the epidermis with such a force, the outer cylinder 2 moves to the tip side vigorously, and the puncture needle 6 is punctured into the living body vigorously. Therefore, the puncture needle 6 can be punctured into the living body more reliably.
　ここで、前述したように、シリンジ１では、穿刺針６の長さ（穿刺深さ）が０．５ｍｍ～３．０ｍｍ程度と短い。そのため、例えば、穿刺針６をゆっくり生体に穿刺しようとすると、表皮が穿刺針６に押圧されて凹没するだけで、穿刺針６が生体に穿刺されないおそれがある。そこで、シリンジ１のように、使用者の操作によって穿刺針６が勢いよく生体に穿刺される構成とすることにより、上述した問題を解消し、確実に穿刺針６を生体に穿刺することができる。 Here, as described above, in the syringe 1, the length of the puncture needle 6 (puncture depth) is as short as about 0.5 mm to 3.0 mm. Therefore, for example, when the puncture needle 6 is slowly punctured into the living body, there is a possibility that the puncture needle 6 may not be punctured into the living body simply because the epidermis is pressed by the puncture needle 6 and recessed. Thus, by adopting a configuration in which the puncture needle 6 is punctured into the living body vigorously by the user's operation like the syringe 1, the above-described problems can be solved and the puncture needle 6 can be punctured into the living body reliably. .
　また、前述したように、操作［３］にて、当接部５は、外力Ｇ１が作用することにより、潰れつつ収納部５ａの開口が拡径するように変形する。このように、収納部５ａの開口が拡径することにより、穿刺部位の周囲の表皮が外側に引っ張られるため、表皮のたるみを少なくすることができ、穿刺針６の穿刺をより確実に行うことができる。 Further, as described above, in operation [3], the contact portion 5 is deformed so that the opening of the storage portion 5a is expanded while being crushed by the application of the external force G1. In this way, since the diameter of the opening of the storage portion 5a expands the epidermis around the puncture site, the sagging of the epidermis can be reduced, and the puncture needle 6 can be punctured more reliably. Can do.
　また、前述したように、シリンジ１は、操作の途中でツメ部４１２が破損するように構成されている。これにより、一度使用したシリンジ１を再利用することができなくなるため、シリンジ１の安全性が向上する。 Further, as described above, the syringe 1 is configured such that the claw portion 412 is broken during the operation. Thereby, since the syringe 1 once used cannot be reused, the safety of the syringe 1 is improved.
　＜第２実施形態＞
　次いで、本発明のシリンジの第２実施形態を説明する。 <Second Embodiment>
Next, a second embodiment of the syringe of the present invention will be described.
　図４は、本発明のシリンジの第２実施形態を示す縦断面図である。 FIG. 4 is a longitudinal sectional view showing a second embodiment of the syringe of the present invention.
　以下、本実施形態のシリンジについて説明するが、第１実施形態のシリンジとの相違点を中心に説明し、同様の事項については、その説明を省略する。 Hereinafter, although the syringe of this embodiment is demonstrated, it demonstrates centering around difference with the syringe of 1st Embodiment, and abbreviate | omits the description about the same matter.
　本実施形態のシリンジは、当接部の構成が異なる以外は、第１実施形態のシリンジと同様である。 The syringe of the present embodiment is the same as the syringe of the first embodiment except that the configuration of the contact portion is different.
　図４に示すシリンジ１Ａでは、当接部５Ａが有する各分割片５３に、他の部分よりも厚さが薄い脆弱部５４Ａが形成されている。この脆弱部５４Ａは、各分割片５３の幅方向の全域に形成されている。また、各脆弱部５４Ａは、突出部５１２の先端よりも基端側に位置している。 In the syringe 1A shown in FIG. 4, each of the divided pieces 53 included in the contact portion 5A is formed with a fragile portion 54A that is thinner than other portions. The fragile portion 54A is formed in the entire width direction of each divided piece 53. Further, each fragile portion 54 </ b> A is located closer to the proximal end than the distal end of the protruding portion 512.
　このような構成の当接部５は、所定の大きさ以上の力によって表皮に押し付けられ、前述した第１実施形態で述べた外力Ｇ１が加わると、潰れつつ開口が拡径するように変形するとともに、各分割片５３の脆弱部５４Ａから先端側が折れ曲がって破損するように構成されている。各分割片５３が折れ曲がると、突出部５１２および穿刺針６が収納部５ａから先端側へ突出し、突出部５１２が表皮を押し付けるとともに、穿刺針６が生体に穿刺される。 The contact portion 5 having such a configuration is pressed against the skin by a force of a predetermined magnitude or more, and when the external force G1 described in the first embodiment is applied, the contact portion 5 is deformed so that the opening is expanded while being crushed. At the same time, the front end side is bent from the fragile portion 54A of each divided piece 53 so as to be broken. When each divided piece 53 is bent, the protruding portion 512 and the puncture needle 6 protrude from the storage portion 5a toward the distal end, the protruding portion 512 presses the epidermis, and the puncture needle 6 is punctured into the living body.
　このような当接部５によれば、穿刺針６をより確実に生体に穿刺することができる。具体的には、前述したように、穿刺針６を生体に穿刺するには、各分割片５３の脆弱部５４Ａから先端側を折り曲げなければならない。そのためには、使用者は、ある程度大きな押圧力で当接部５を表皮に押し付けなければならない。 According to such a contact portion 5, the puncture needle 6 can be punctured more reliably into the living body. Specifically, as described above, in order to puncture the living body with the puncture needle 6, the distal end side must be bent from the fragile portion 54 </ b> A of each divided piece 53. For this purpose, the user must press the contact portion 5 against the skin with a large pressing force.
　このような力で当接部５を表皮に押し付けると、各分割片５３が脆弱部５４Ａで折れ曲がるとともに、穿刺針６が勢いよく先端側へ移動し、勢いよく生体に穿刺される。そのため、穿刺針６をより確実に生体に穿刺することができる。 When the contact portion 5 is pressed against the epidermis with such a force, each divided piece 53 is bent at the fragile portion 54A, and the puncture needle 6 is moved to the tip side vigorously and punctured into the living body vigorously. Therefore, the puncture needle 6 can be punctured into the living body more reliably.
　また、前述したように、当接部５は、脆弱部５４Ａで折れ曲がることによって破損するように構成されている。これにより、一度使用したシリンジ１Ａを再利用することができなくなるため、シリンジ１Ａの安全性が向上する。 Further, as described above, the contact portion 5 is configured to be broken by being bent at the fragile portion 54A. Thereby, since the syringe 1A once used cannot be reused, the safety of the syringe 1A is improved.
　以上、本発明のシリンジを図示の実施形態について説明したが、本発明は、これに限定されるものではなく、シリンジを構成する各部は、同様の機能を発揮し得る任意の構成のものと置換することができる。また、任意の構成物が付加されていてもよい。 As mentioned above, although the syringe of this invention was demonstrated about embodiment of illustration, this invention is not limited to this, Each part which comprises a syringe substitutes the thing of the arbitrary structures which can exhibit the same function. can do. Moreover, arbitrary components may be added.
　また、本発明のシリンジは、前記各実施形態のうちの、任意の２以上の構成（特徴）を組み合わせたものであってもよい。 Further, the syringe of the present invention may be a combination of any two or more configurations (features) of the above embodiments.
　本発明によれば、操作性に優れるシリンジを提供することができる。具体的には、例えば、把持部を把持して、生体に押し付けると、まず当接部が生体に当接してシリンジの姿勢が保たれ、さらに把持部を生体に押し付けると、穿刺針が生体に穿刺され、さらに把持部を生体に押し付けると、薬液が穿刺針から生体内へ注入される。すなわち、把持部を生体へ押し付ける１つのステップで薬液の投与が完了する。また、このような操作方法によれば、腕の力を利用して薬液を皮内に注入することができるため、充分な力でシリンジの操作を行うことができる。また、本発明によれば、穿刺針を勢いよく生体に穿刺することができるため、例えば穿刺針が短い場合であっても、確実に穿刺針を生体に穿刺することができる。以上より、操作性に優れるシリンジとなる。さらに操作性が向上することにより投与ミス等も防止でき、信頼性および安全性も向上する。 According to the present invention, a syringe excellent in operability can be provided. Specifically, for example, when a gripping part is gripped and pressed against a living body, the abutting part first contacts the living body and the posture of the syringe is maintained. When the gripping part is further pressed against the living body, the puncture needle is pressed against the living body. When the puncture is performed and the grasping portion is further pressed against the living body, the drug solution is injected from the puncture needle into the living body. That is, the administration of the drug solution is completed in one step of pressing the grip portion against the living body. Moreover, according to such an operation method, since a chemical | medical solution can be inject | poured into skin using the force of an arm, operation of a syringe can be performed with sufficient force. Furthermore, according to the present invention, since the puncture needle can be punctured into the living body vigorously, for example, even when the puncture needle is short, the puncture needle can be reliably punctured into the living body. From the above, the syringe has excellent operability. Furthermore, by improving operability, administration errors can be prevented, and reliability and safety are also improved.
　したがって、産業上の利用可能性を有する。 Therefore, it has industrial applicability.

Claims (7)

  1. 　先端側に口部を有する外筒と、
    　前記口部に接続され、生体を穿刺可能な針先を有する穿刺針と、
    　前記外筒内で摺動し得るガスケットと、
    　前記外筒と前記ガスケットとで囲まれる空間に収納された薬液と、
    　前記穿刺針を前記生体に穿刺するのに先立って前記生体に当接させる当接部と、
    　前記外筒に対して該外筒の長手方向に移動可能に設けられ、前記ガスケットを前記外筒の先端側に移動操作する押し子と、
    　前記押し子の前記外筒に対する先端側への移動を規制する移動規制手段とを有し、
    　前記押し子は、前記外筒の外周の少なくとも一部を覆うとともに前記外筒に対して該外筒の長手方向に移動可能に設けられた筒状の把持部と、該把持部と連結するとともに前記外筒内に挿入され、前記把持部の前記外筒に対する先端側への移動によって前記ガスケットを先端側へ移動させる押圧部とを有し、
    　前記当接部は、先端側に開口し、内側に前記穿刺針を収納する収納部を有し、
    　前記当接部を前記生体に当接させた状態にて、前記押し子を第１の押圧力で前記生体に押し込むと、前記当接部が前記外筒の長手方向に潰れるように変形することにより前記収納部の前記開口から前記穿刺針が突出し、前記穿刺針が前記生体に穿刺された穿刺状態となり、
    　前記穿刺状態から前記押し子を前記第１の押圧力よりも大きな第２の押圧力で前記生体に押し込むと、前記移動規制手段による規制が解除され、前記押し子が前記外筒に対して先端側へ移動し、これにより前記ガスケットが先端側へ移動し、前記穿刺針から前記生体内に薬液が注入されるように構成されていることを特徴とするシリンジ。     An outer cylinder having a mouth on the tip side;
    A puncture needle connected to the mouth and having a needle tip capable of puncturing a living body;
    A gasket that can slide in the outer cylinder;
    A chemical solution stored in a space surrounded by the outer cylinder and the gasket;
    An abutting portion that abuts the living body prior to puncturing the living body with the puncture needle;
    A pusher which is provided so as to be movable in the longitudinal direction of the outer cylinder with respect to the outer cylinder, and which moves the gasket toward the distal end side of the outer cylinder;
    Movement restricting means for restricting movement of the pusher toward the distal end side with respect to the outer cylinder,
    The pusher covers at least a part of the outer periphery of the outer cylinder and is connected to the cylindrical gripping part provided to be movable in the longitudinal direction of the outer cylinder with respect to the outer cylinder. A pressing portion that is inserted into the outer cylinder and moves the gasket toward the distal end side by moving the gripping portion toward the distal end side with respect to the outer cylinder;
    The contact portion has an accommodating portion that opens to the distal end side and accommodates the puncture needle inside.
    When the pusher is pushed into the living body with the first pressing force in a state where the abutting part is in contact with the living body, the contacting part is deformed so as to be crushed in the longitudinal direction of the outer cylinder. The puncture needle protrudes from the opening of the storage portion, and the puncture needle is punctured into the living body.
    When the pusher is pushed into the living body with a second pressing force larger than the first pressing force from the puncture state, the restriction by the movement restricting means is released, and the pusher is distal to the outer cylinder. The syringe is configured to move to the side, whereby the gasket moves to the distal end side, and the drug solution is injected into the living body from the puncture needle.
  2. 　前記当接部は、ドーム型の基体と、前記基体の外周から中央部に向けて形成された複数のスリットとを有している請求項１に記載のシリンジ。 The syringe according to claim 1, wherein the contact portion includes a dome-shaped base and a plurality of slits formed from an outer periphery of the base toward a central portion.
  3. 　前記押し子を前記第１の押圧力で前記生体に押し込むと、前記当接部は、前記外筒の長手方向に潰れつつ、前記収納部の前記開口が拡径するように変形する請求項２に記載のシリンジ。 3. When the pusher is pushed into the living body with the first pressing force, the contact portion is deformed so that the opening of the storage portion is expanded while being crushed in the longitudinal direction of the outer cylinder. The syringe according to 1.
  4. 　前記当接部は、前記スリットによって分割された複数の分割片と、前記分割片の延在方向の途中に設けられた脆弱部とを有しており、前記押し子を前記第１の押圧力で前記生体に押し込むと、前記分割片が前記脆弱部で折れ曲がるように変形する請求項１に記載のシリンジ。 The contact portion includes a plurality of divided pieces divided by the slit and a weakened portion provided in the middle of the extending direction of the divided pieces, and the pusher is moved to the first pressing force. The syringe according to claim 1, wherein the divided piece is deformed so as to be bent at the weakened portion when pushed into the living body.
  5. 　前記当接部は、前記分割片が前記脆弱部で折れ曲がることによって破損する請求項４に記載のシリンジ。 The syringe according to claim 4, wherein the abutting portion is broken when the divided piece is bent at the fragile portion.
  6. 　前記当接部は、前記収納部内に突出し、前記穿刺針の周囲を囲むように設けられた突出部を有し、
    　前記突出部は、前記第１の押圧力によって前記当接部が変形した状態で、前記生体を押圧する請求項１に記載のシリンジ。     The contact portion protrudes into the storage portion, and has a protrusion provided to surround the puncture needle,
    The syringe according to claim 1, wherein the protruding portion presses the living body in a state where the contact portion is deformed by the first pressing force.
  7. 　前記移動規制手段は、前記第２の押圧力によって破損するよう構成されている請求項１に記載のシリンジ。 The syringe according to claim 1, wherein the movement restricting means is configured to be damaged by the second pressing force.
PCT/JP2012/068003 2011-09-29 2012-07-13 Syringe WO2013046868A1 (en)

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WO2016158756A1 (en) * 2015-03-31 2016-10-06 テルモ株式会社 Intradermal formulation for regenerative medicine
JPWO2016158756A1 (en) * 2015-03-31 2018-02-01 テルモ株式会社 Intradermal preparation for regenerative medicine
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JPWO2020138193A1 (en) * 2018-12-25 2021-02-18 国立大学法人弘前大学 Drug administration device and drug administration system
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