DE3116067C2 - - Google Patents

Info

Publication number
DE3116067C2
DE3116067C2 DE3116067A DE3116067A DE3116067C2 DE 3116067 C2 DE3116067 C2 DE 3116067C2 DE 3116067 A DE3116067 A DE 3116067A DE 3116067 A DE3116067 A DE 3116067A DE 3116067 C2 DE3116067 C2 DE 3116067C2
Authority
DE
Germany
Prior art keywords
mta
radical
general formula
hydrogen
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3116067A
Other languages
German (de)
English (en)
Other versions
DE3116067A1 (de
Inventor
Giorgio Mailand/Milano It Stramentinoli
Federico Trucazzano Mailand/Milano It Gennari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioresearch SRL
Original Assignee
BIORESEARCH Srl LISCATE MAILAND/MILANO IT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BIORESEARCH Srl LISCATE MAILAND/MILANO IT filed Critical BIORESEARCH Srl LISCATE MAILAND/MILANO IT
Publication of DE3116067A1 publication Critical patent/DE3116067A1/de
Application granted granted Critical
Publication of DE3116067C2 publication Critical patent/DE3116067C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19813116067 1980-04-22 1981-04-22 Therapeutische zusammensetzungen mit schmerzstillenden und entzuendungshemmenden eigenschaften, die als wirkstoffe adenosinderivate enthalten Granted DE3116067A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21550/80A IT1193529B (it) 1980-04-22 1980-04-22 Derivati adenosinici ad attivita' antinfiammatoria ed analgesica e composizioni terapeutiche che li contengono come principio attivo

Publications (2)

Publication Number Publication Date
DE3116067A1 DE3116067A1 (de) 1982-03-11
DE3116067C2 true DE3116067C2 (pt) 1992-12-17

Family

ID=11183457

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19813116067 Granted DE3116067A1 (de) 1980-04-22 1981-04-22 Therapeutische zusammensetzungen mit schmerzstillenden und entzuendungshemmenden eigenschaften, die als wirkstoffe adenosinderivate enthalten

Country Status (17)

Country Link
JP (2) JPS56166117A (pt)
AR (1) AR231144A1 (pt)
BE (1) BE888472A (pt)
CA (1) CA1198105A (pt)
CH (2) CH650514A5 (pt)
DE (1) DE3116067A1 (pt)
DK (1) DK159453C (pt)
ES (2) ES8206551A1 (pt)
FI (1) FI70227C (pt)
FR (1) FR2491761A1 (pt)
GB (3) GB2074446B (pt)
IT (1) IT1193529B (pt)
LU (1) LU83307A1 (pt)
MX (1) MX9203630A (pt)
NL (1) NL192111C (pt)
NO (1) NO150515C (pt)
SE (3) SE460198B (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011005232A1 (de) * 2011-03-08 2012-09-13 AristoCon GmbH & Co. KG Adenosin und seine Derivate zur Verwendung in der Schmerztherapie

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1177373B (it) * 1984-12-06 1987-08-26 Bioresearch Spa Sali della 5'-metiltio-5'-deossiadenosina con acidi solfonici a lunga catena alchilica
IT1227049B (it) * 1988-07-29 1991-03-14 Bioresearch Spa Impiego di derivati adenosinici per la preparazione di composizioni farmaceutiche aventi attivita' immunostimolante.
JPH0497287A (ja) * 1990-08-10 1992-03-30 Nec Ic Microcomput Syst Ltd 画像表示集積回路
DK1891961T3 (da) * 2005-03-17 2009-12-21 Proyecto Biomedicina Cima Sl Anvendelse af 5'-methylthioadenosin (MTA) i forebyggelsen og/eller behandling af autoimmune sygdomme og/eller transplantatafstödning
ES2259552B1 (es) * 2005-03-17 2007-06-16 Proyecto De Biomedicina Cima, S.L. Empleo de 5'-metiltioadenosina (mta) en la prevencion y/o tratamiento de enfermedades autoinmunes y/o rechazo de transplantes.
DE102010027595A1 (de) * 2010-07-23 2012-01-26 Helmut Vorbrüggen Vermeidung von Ischämie- oder Degenerations-Schäden im Gehirn bei Anwendung von Adenosin-Derivaten
JP6214628B2 (ja) * 2013-04-05 2017-10-18 ライオン株式会社 内服組成物
WO2014163152A1 (ja) * 2013-04-05 2014-10-09 ライオン株式会社 ノンレム睡眠促進剤、深睡眠促進剤および自然睡眠誘発剤
KR20150139508A (ko) * 2013-04-05 2015-12-11 라이온 가부시키가이샤 효모 배양물 및 내복 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1259341B (de) * 1962-12-22 1968-01-25 Boehringer & Soehne Gmbh Verfahren zur Herstellung neuer 5'-Sulfoxyde von Nucleosiden
DE1545645A1 (de) * 1965-12-06 1969-08-21 Boehringer Mannheim Gmbh Verfahren zur Herstellung von disubstituierten Adenosin-Derivaten
FR2252405B1 (pt) * 1973-11-27 1978-04-28 Ajinomoto Kk
FR2313937A1 (fr) * 1975-06-09 1977-01-07 Anvar Medicament a base de 5' thioethers de l'adenosine
FR2424027A1 (fr) * 1978-04-28 1979-11-23 Merieux Inst Nouveau medicament, notamment sedatif et inducteur de sommeil et compositions pharmaceutiques la renfermant

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011005232A1 (de) * 2011-03-08 2012-09-13 AristoCon GmbH & Co. KG Adenosin und seine Derivate zur Verwendung in der Schmerztherapie

Also Published As

Publication number Publication date
GB8413454D0 (en) 1984-07-04
GB2144409A (en) 1985-03-06
GB8321947D0 (en) 1983-09-14
ES8306378A1 (es) 1983-06-01
JPH01301692A (ja) 1989-12-05
NO150515C (no) 1984-10-31
SE8700914L (sv) 1987-03-04
FI811249L (fi) 1981-10-23
FR2491761A1 (fr) 1982-04-16
SE8700913L (sv) 1987-03-04
DE3116067A1 (de) 1982-03-11
FI70227C (fi) 1986-09-15
SE460198B (sv) 1989-09-18
BE888472A (fr) 1981-08-17
SE8700913D0 (sv) 1987-03-04
CA1198105A (en) 1985-12-17
GB2074446B (en) 1985-04-11
SE8700914D0 (sv) 1987-03-04
GB2144409B (en) 1985-09-11
CH645544A5 (de) 1984-10-15
FI70227B (fi) 1986-02-28
NO811346L (no) 1981-10-23
FR2491761B1 (pt) 1984-01-06
NL8101984A (nl) 1981-11-16
NL192111C (nl) 1997-02-04
SE8102489L (sv) 1981-10-23
ES501539A0 (es) 1982-08-16
JPH0249288B2 (pt) 1990-10-29
AR231144A1 (es) 1984-09-28
LU83307A1 (fr) 1981-07-24
ES511039A0 (es) 1983-06-01
DK159453C (da) 1991-03-18
DK159453B (da) 1990-10-15
JPS56166117A (en) 1981-12-21
CH650514A5 (de) 1985-07-31
MX9203630A (es) 1992-09-01
NL192111B (nl) 1996-10-01
GB2074446A (en) 1981-11-04
IT1193529B (it) 1988-07-08
SE464635B (sv) 1991-05-27
SE466238B (sv) 1992-01-20
GB2144038B (en) 1985-08-29
GB2144038A (en) 1985-02-27
NO150515B (no) 1984-07-23
ES8206551A1 (es) 1982-08-16
IT8021550A0 (it) 1980-04-22
JPH0246599B2 (pt) 1990-10-16
DK176481A (da) 1981-10-23

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8125 Change of the main classification

Ipc: A61K 31/70

D2 Grant after examination
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BIORESEARCH S.P.A., LISCATE, MAILAND/MILANO, IT

8328 Change in the person/name/address of the agent

Free format text: HOFFMANN, EITLE & PARTNER PATENT- UND RECHTSANWAELTE, 81925 MUENCHEN

8339 Ceased/non-payment of the annual fee