DE3116067A1 - Therapeutische zusammensetzungen mit schmerzstillenden und entzuendungshemmenden eigenschaften, die als wirkstoffe adenosinderivate enthalten - Google Patents

Therapeutische zusammensetzungen mit schmerzstillenden und entzuendungshemmenden eigenschaften, die als wirkstoffe adenosinderivate enthalten

Info

Publication number
DE3116067A1
DE3116067A1 DE19813116067 DE3116067A DE3116067A1 DE 3116067 A1 DE3116067 A1 DE 3116067A1 DE 19813116067 DE19813116067 DE 19813116067 DE 3116067 A DE3116067 A DE 3116067A DE 3116067 A1 DE3116067 A1 DE 3116067A1
Authority
DE
Germany
Prior art keywords
radical
general formula
hydrogen
compound
mta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19813116067
Other languages
German (de)
English (en)
Other versions
DE3116067C2 (es
Inventor
Federico Trucazzano Milano Gennari
Giorgio Milano Stramentinoli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioresearch SRL
Original Assignee
Bioresearch Liscate Milano Srl
Bioresearch SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch Liscate Milano Srl, Bioresearch SRL filed Critical Bioresearch Liscate Milano Srl
Publication of DE3116067A1 publication Critical patent/DE3116067A1/de
Application granted granted Critical
Publication of DE3116067C2 publication Critical patent/DE3116067C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19813116067 1980-04-22 1981-04-22 Therapeutische zusammensetzungen mit schmerzstillenden und entzuendungshemmenden eigenschaften, die als wirkstoffe adenosinderivate enthalten Granted DE3116067A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21550/80A IT1193529B (it) 1980-04-22 1980-04-22 Derivati adenosinici ad attivita' antinfiammatoria ed analgesica e composizioni terapeutiche che li contengono come principio attivo

Publications (2)

Publication Number Publication Date
DE3116067A1 true DE3116067A1 (de) 1982-03-11
DE3116067C2 DE3116067C2 (es) 1992-12-17

Family

ID=11183457

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19813116067 Granted DE3116067A1 (de) 1980-04-22 1981-04-22 Therapeutische zusammensetzungen mit schmerzstillenden und entzuendungshemmenden eigenschaften, die als wirkstoffe adenosinderivate enthalten

Country Status (17)

Country Link
JP (2) JPS56166117A (es)
AR (1) AR231144A1 (es)
BE (1) BE888472A (es)
CA (1) CA1198105A (es)
CH (2) CH650514A5 (es)
DE (1) DE3116067A1 (es)
DK (1) DK159453C (es)
ES (2) ES8206551A1 (es)
FI (1) FI70227C (es)
FR (1) FR2491761A1 (es)
GB (3) GB2074446B (es)
IT (1) IT1193529B (es)
LU (1) LU83307A1 (es)
MX (1) MX9203630A (es)
NL (1) NL192111C (es)
NO (1) NO150515C (es)
SE (3) SE460198B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1177373B (it) * 1984-12-06 1987-08-26 Bioresearch Spa Sali della 5'-metiltio-5'-deossiadenosina con acidi solfonici a lunga catena alchilica
IT1227049B (it) * 1988-07-29 1991-03-14 Bioresearch Spa Impiego di derivati adenosinici per la preparazione di composizioni farmaceutiche aventi attivita' immunostimolante.
JPH0497287A (ja) * 1990-08-10 1992-03-30 Nec Ic Microcomput Syst Ltd 画像表示集積回路
ES2334924T3 (es) * 2005-03-17 2010-03-17 Proyecto De Biomedicina Cima, S.L. Empleo de 5'-metiltioadenosina (mta) en la prevencion y/o tratamiento de enfermedades autoinmunes y/o rechazo de trasplantes.
ES2259552B1 (es) * 2005-03-17 2007-06-16 Proyecto De Biomedicina Cima, S.L. Empleo de 5'-metiltioadenosina (mta) en la prevencion y/o tratamiento de enfermedades autoinmunes y/o rechazo de transplantes.
DE102010027595A1 (de) * 2010-07-23 2012-01-26 Helmut Vorbrüggen Vermeidung von Ischämie- oder Degenerations-Schäden im Gehirn bei Anwendung von Adenosin-Derivaten
DE102011005232A1 (de) * 2011-03-08 2012-09-13 AristoCon GmbH & Co. KG Adenosin und seine Derivate zur Verwendung in der Schmerztherapie
JP6214628B2 (ja) * 2013-04-05 2017-10-18 ライオン株式会社 内服組成物
WO2014163152A1 (ja) * 2013-04-05 2014-10-09 ライオン株式会社 ノンレム睡眠促進剤、深睡眠促進剤および自然睡眠誘発剤
WO2014163151A1 (ja) * 2013-04-05 2014-10-09 ライオン株式会社 酵母培養物及び内服組成物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3212954A (en) * 1962-12-22 1965-10-19 Boehringer & Soehne Gmbh Nucleoside-5'-sulfoxides
GB1101108A (en) * 1965-12-06 1968-01-31 Boehringer & Soehne Gmbh Disubstituted adenosine derivatives
GB1436509A (en) * 1973-11-27 1976-05-19 Ajinomoto Kk Method for producing s-adenosylmethionine or methylthioadenosine from yeast

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2313937A1 (fr) * 1975-06-09 1977-01-07 Anvar Medicament a base de 5' thioethers de l'adenosine
FR2424027A1 (fr) * 1978-04-28 1979-11-23 Merieux Inst Nouveau medicament, notamment sedatif et inducteur de sommeil et compositions pharmaceutiques la renfermant

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3212954A (en) * 1962-12-22 1965-10-19 Boehringer & Soehne Gmbh Nucleoside-5'-sulfoxides
GB1101108A (en) * 1965-12-06 1968-01-31 Boehringer & Soehne Gmbh Disubstituted adenosine derivatives
GB1436509A (en) * 1973-11-27 1976-05-19 Ajinomoto Kk Method for producing s-adenosylmethionine or methylthioadenosine from yeast

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Eur. J. Med. Chem. 12, 2, 1977, S.105-108 *
J. Chem. Soc., 1953, S.2662 *

Also Published As

Publication number Publication date
GB2144038B (en) 1985-08-29
GB8413454D0 (en) 1984-07-04
SE466238B (sv) 1992-01-20
SE8700913L (sv) 1987-03-04
DK176481A (da) 1981-10-23
NO150515C (no) 1984-10-31
JPH01301692A (ja) 1989-12-05
SE460198B (sv) 1989-09-18
ES511039A0 (es) 1983-06-01
NO811346L (no) 1981-10-23
CA1198105A (en) 1985-12-17
CH650514A5 (de) 1985-07-31
NO150515B (no) 1984-07-23
FI70227C (fi) 1986-09-15
GB2144409B (en) 1985-09-11
GB2144409A (en) 1985-03-06
SE8700914L (sv) 1987-03-04
MX9203630A (es) 1992-09-01
JPS56166117A (en) 1981-12-21
NL8101984A (nl) 1981-11-16
FI811249L (fi) 1981-10-23
DK159453B (da) 1990-10-15
JPH0246599B2 (es) 1990-10-16
GB2144038A (en) 1985-02-27
GB2074446B (en) 1985-04-11
SE8102489L (sv) 1981-10-23
ES501539A0 (es) 1982-08-16
NL192111C (nl) 1997-02-04
DE3116067C2 (es) 1992-12-17
DK159453C (da) 1991-03-18
ES8206551A1 (es) 1982-08-16
FI70227B (fi) 1986-02-28
LU83307A1 (fr) 1981-07-24
IT1193529B (it) 1988-07-08
GB8321947D0 (en) 1983-09-14
FR2491761B1 (es) 1984-01-06
SE464635B (sv) 1991-05-27
NL192111B (nl) 1996-10-01
JPH0249288B2 (es) 1990-10-29
FR2491761A1 (fr) 1982-04-16
CH645544A5 (de) 1984-10-15
IT8021550A0 (it) 1980-04-22
BE888472A (fr) 1981-08-17
GB2074446A (en) 1981-11-04
AR231144A1 (es) 1984-09-28
SE8700914D0 (sv) 1987-03-04
ES8306378A1 (es) 1983-06-01
SE8700913D0 (sv) 1987-03-04

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8125 Change of the main classification

Ipc: A61K 31/70

D2 Grant after examination
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BIORESEARCH S.P.A., LISCATE, MAILAND/MILANO, IT

8328 Change in the person/name/address of the agent

Free format text: HOFFMANN, EITLE & PARTNER PATENT- UND RECHTSANWAELTE, 81925 MUENCHEN

8339 Ceased/non-payment of the annual fee