CH650514A5 - Verfahren zur herstellung von 5'-desoxy-5'-methylthioadenosin. - Google Patents

Verfahren zur herstellung von 5'-desoxy-5'-methylthioadenosin. Download PDF

Info

Publication number
CH650514A5
CH650514A5 CH4716/84A CH471684A CH650514A5 CH 650514 A5 CH650514 A5 CH 650514A5 CH 4716/84 A CH4716/84 A CH 4716/84A CH 471684 A CH471684 A CH 471684A CH 650514 A5 CH650514 A5 CH 650514A5
Authority
CH
Switzerland
Prior art keywords
mta
agglomeration
platelet
tests
induced
Prior art date
Application number
CH4716/84A
Other languages
German (de)
English (en)
Inventor
Giorgio Stramentinoli
Federico Gennari
Original Assignee
Bioresearch Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch Spa filed Critical Bioresearch Spa
Publication of CH650514A5 publication Critical patent/CH650514A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH4716/84A 1980-04-22 1981-04-22 Verfahren zur herstellung von 5'-desoxy-5'-methylthioadenosin. CH650514A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21550/80A IT1193529B (it) 1980-04-22 1980-04-22 Derivati adenosinici ad attivita' antinfiammatoria ed analgesica e composizioni terapeutiche che li contengono come principio attivo

Publications (1)

Publication Number Publication Date
CH650514A5 true CH650514A5 (de) 1985-07-31

Family

ID=11183457

Family Applications (2)

Application Number Title Priority Date Filing Date
CH263281A CH645544A5 (de) 1980-04-22 1981-04-22 Therapeutisches, adenosin-derivate mit entzuendungshemmender, analgetischer und antipyretischer wirksamkeit enthaltendes mittel.
CH4716/84A CH650514A5 (de) 1980-04-22 1981-04-22 Verfahren zur herstellung von 5'-desoxy-5'-methylthioadenosin.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH263281A CH645544A5 (de) 1980-04-22 1981-04-22 Therapeutisches, adenosin-derivate mit entzuendungshemmender, analgetischer und antipyretischer wirksamkeit enthaltendes mittel.

Country Status (17)

Country Link
JP (2) JPS56166117A (es)
AR (1) AR231144A1 (es)
BE (1) BE888472A (es)
CA (1) CA1198105A (es)
CH (2) CH645544A5 (es)
DE (1) DE3116067A1 (es)
DK (1) DK159453C (es)
ES (2) ES8206551A1 (es)
FI (1) FI70227C (es)
FR (1) FR2491761A1 (es)
GB (3) GB2074446B (es)
IT (1) IT1193529B (es)
LU (1) LU83307A1 (es)
MX (1) MX9203630A (es)
NL (1) NL192111C (es)
NO (1) NO150515C (es)
SE (3) SE460198B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1177373B (it) * 1984-12-06 1987-08-26 Bioresearch Spa Sali della 5'-metiltio-5'-deossiadenosina con acidi solfonici a lunga catena alchilica
IT1227049B (it) * 1988-07-29 1991-03-14 Bioresearch Spa Impiego di derivati adenosinici per la preparazione di composizioni farmaceutiche aventi attivita' immunostimolante.
JPH0497287A (ja) * 1990-08-10 1992-03-30 Nec Ic Microcomput Syst Ltd 画像表示集積回路
MX2007011327A (es) 2005-03-17 2008-01-28 Proyecto Biomedicina Cima Sl Empleo de 5'-metiltioadenosina (mta) en la prevencion y/o tratamiento de enfermedades autoinmunes y/o rechazo de transplantes.
ES2259552B1 (es) * 2005-03-17 2007-06-16 Proyecto De Biomedicina Cima, S.L. Empleo de 5'-metiltioadenosina (mta) en la prevencion y/o tratamiento de enfermedades autoinmunes y/o rechazo de transplantes.
DE102010027595A1 (de) * 2010-07-23 2012-01-26 Helmut Vorbrüggen Vermeidung von Ischämie- oder Degenerations-Schäden im Gehirn bei Anwendung von Adenosin-Derivaten
DE102011005232A1 (de) * 2011-03-08 2012-09-13 AristoCon GmbH & Co. KG Adenosin und seine Derivate zur Verwendung in der Schmerztherapie
WO2014163151A1 (ja) * 2013-04-05 2014-10-09 ライオン株式会社 酵母培養物及び内服組成物
WO2014163152A1 (ja) * 2013-04-05 2014-10-09 ライオン株式会社 ノンレム睡眠促進剤、深睡眠促進剤および自然睡眠誘発剤
WO2014163150A1 (ja) * 2013-04-05 2014-10-09 ライオン株式会社 内服組成物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1259341B (de) * 1962-12-22 1968-01-25 Boehringer & Soehne Gmbh Verfahren zur Herstellung neuer 5'-Sulfoxyde von Nucleosiden
DE1545645A1 (de) * 1965-12-06 1969-08-21 Boehringer Mannheim Gmbh Verfahren zur Herstellung von disubstituierten Adenosin-Derivaten
FR2252405B1 (es) * 1973-11-27 1978-04-28 Ajinomoto Kk
FR2313937A1 (fr) * 1975-06-09 1977-01-07 Anvar Medicament a base de 5' thioethers de l'adenosine
FR2424027A1 (fr) * 1978-04-28 1979-11-23 Merieux Inst Nouveau medicament, notamment sedatif et inducteur de sommeil et compositions pharmaceutiques la renfermant

Also Published As

Publication number Publication date
ES511039A0 (es) 1983-06-01
SE8700914L (sv) 1987-03-04
SE8700914D0 (sv) 1987-03-04
GB8413454D0 (en) 1984-07-04
GB2074446B (en) 1985-04-11
SE8700913D0 (sv) 1987-03-04
NL192111B (nl) 1996-10-01
FI70227C (fi) 1986-09-15
GB8321947D0 (en) 1983-09-14
DK159453B (da) 1990-10-15
MX9203630A (es) 1992-09-01
ES501539A0 (es) 1982-08-16
JPH0246599B2 (es) 1990-10-16
FI811249L (fi) 1981-10-23
SE464635B (sv) 1991-05-27
DK176481A (da) 1981-10-23
SE460198B (sv) 1989-09-18
DE3116067A1 (de) 1982-03-11
BE888472A (fr) 1981-08-17
ES8306378A1 (es) 1983-06-01
LU83307A1 (fr) 1981-07-24
FI70227B (fi) 1986-02-28
NL192111C (nl) 1997-02-04
NO150515C (no) 1984-10-31
NL8101984A (nl) 1981-11-16
JPH0249288B2 (es) 1990-10-29
AR231144A1 (es) 1984-09-28
FR2491761B1 (es) 1984-01-06
FR2491761A1 (fr) 1982-04-16
CH645544A5 (de) 1984-10-15
ES8206551A1 (es) 1982-08-16
GB2144409B (en) 1985-09-11
SE8700913L (sv) 1987-03-04
IT8021550A0 (it) 1980-04-22
IT1193529B (it) 1988-07-08
NO811346L (no) 1981-10-23
CA1198105A (en) 1985-12-17
GB2144038A (en) 1985-02-27
GB2074446A (en) 1981-11-04
JPS56166117A (en) 1981-12-21
SE8102489L (sv) 1981-10-23
NO150515B (no) 1984-07-23
DE3116067C2 (es) 1992-12-17
DK159453C (da) 1991-03-18
GB2144038B (en) 1985-08-29
SE466238B (sv) 1992-01-20
GB2144409A (en) 1985-03-06
JPH01301692A (ja) 1989-12-05

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Legal Events

Date Code Title Description
PFA Name/firm changed

Owner name: BIORESEARCH S.P.A.

PL Patent ceased