DE3010599A1 - Derivate von glycinamid, deren herstellung und verwendung - Google Patents

Derivate von glycinamid, deren herstellung und verwendung

Info

Publication number
DE3010599A1
DE3010599A1 DE19803010599 DE3010599A DE3010599A1 DE 3010599 A1 DE3010599 A1 DE 3010599A1 DE 19803010599 DE19803010599 DE 19803010599 DE 3010599 A DE3010599 A DE 3010599A DE 3010599 A1 DE3010599 A1 DE 3010599A1
Authority
DE
Germany
Prior art keywords
group
carbon atoms
linear
branched
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19803010599
Other languages
German (de)
English (en)
Other versions
DE3010599C2 (sh
Inventor
Alexis Cordi
William Van Dorsser
Claude Gillet
Georges Lambelin
Mark Martens
Paul Niebes
Joseph Roba
Romeo Roncucci
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Continental Pharma Inc
Original Assignee
Continental Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from LU81068A external-priority patent/LU81068A1/fr
Priority claimed from LU81069A external-priority patent/LU81069A1/fr
Application filed by Continental Pharma Inc filed Critical Continental Pharma Inc
Publication of DE3010599A1 publication Critical patent/DE3010599A1/de
Application granted granted Critical
Publication of DE3010599C2 publication Critical patent/DE3010599C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19803010599 1979-03-22 1980-03-20 Derivate von glycinamid, deren herstellung und verwendung Granted DE3010599A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU81068A LU81068A1 (fr) 1979-03-22 1979-03-22 Derives de la glycinamide, leur preparation et utilisation, ainsi que compositions contenant ces derives
LU81069A LU81069A1 (fr) 1979-03-22 1979-03-22 Derive de glycinamide, preparation de ce derive, son utilisation ainsi que composition contenant ce derive

Publications (2)

Publication Number Publication Date
DE3010599A1 true DE3010599A1 (de) 1980-10-09
DE3010599C2 DE3010599C2 (sh) 1989-03-02

Family

ID=26640253

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19803010599 Granted DE3010599A1 (de) 1979-03-22 1980-03-20 Derivate von glycinamid, deren herstellung und verwendung
DE3050800A Expired DE3050800C2 (sh) 1979-03-22 1980-03-20

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE3050800A Expired DE3050800C2 (sh) 1979-03-22 1980-03-20

Country Status (18)

Country Link
US (1) US4639468A (sh)
AT (1) AT381302B (sh)
AU (1) AU536499B2 (sh)
CA (1) CA1184567A (sh)
CH (1) CH645091A5 (sh)
DE (2) DE3010599A1 (sh)
DK (1) DK162714C (sh)
ES (1) ES490536A0 (sh)
FI (1) FI82033C (sh)
FR (1) FR2451913A1 (sh)
GB (1) GB2048852B (sh)
GR (1) GR68005B (sh)
IE (1) IE49751B1 (sh)
IL (1) IL59679A (sh)
NL (1) NL191508C (sh)
NO (1) NO157817C (sh)
PT (1) PT70992A (sh)
SE (1) SE453917B (sh)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3329628A1 (de) * 1982-08-20 1984-03-22 MIDIT Société Fiduciaire, Vaduz Derivate der (omega)-aminsaeuren, deren herstellung und verwendung sowie diese derivate enthaltende zubereitungen
US5391577A (en) * 1989-05-25 1995-02-21 Farmitalia Carlo Erba S R L N-phenylalkyl substituted α-amino carboxamide derivatives and process for their preparation
WO1997045115A1 (en) * 1996-05-31 1997-12-04 Trophix Pharmaceuticals, Inc. Pharmaceutical for treatment of neurological and neuropsychiatric disorders
US6191165B1 (en) * 1996-05-31 2001-02-20 Allelix Neuroscience Inc. Pharmaceutical for treatment of neurological and neuropsychiatric disorders
US6667336B2 (en) 2001-02-16 2003-12-23 Nps Allelix Corp. GlyT-1 inhibitors

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2937698A1 (de) * 1979-09-18 1981-04-02 A. Nattermann & Cie GmbH, 5000 Köln N-propionylsarcosinanilide, deren herstellungsverfahren und arzneimittel auf deren basis
US4798687A (en) * 1987-02-06 1989-01-17 Pennwalt Corporation 2-Amino-N-[1,2-Diphenyl-1-(thifluoromethyl)ethyl]acetamide derivatives
US4904681A (en) * 1987-12-01 1990-02-27 G. D. Searle & Co. D-cycloserine and its prodrugs as cognitive enhancers
US4891058A (en) * 1988-07-18 1990-01-02 Ici Americas Inc. 1-alkyl-3-aryl imidazolidine-2,4-diones and herbicidal use
US5278191A (en) * 1988-08-31 1994-01-11 G. D. Searle & Co. Diphenylmethylaminoacetamide derivatives as anti-convulsants
US5288905A (en) * 1988-10-07 1994-02-22 G. D. Searle & Co. Glycyl urea derivatives as anti-convulsants
US4944796A (en) * 1988-11-14 1990-07-31 Ici Americas Inc. Certain 2-(disubstituted amino) acetanilide herbicides
DE3915755A1 (de) * 1989-05-13 1990-11-29 Bayer Ag Fungizide mittel sowie substituierte aminosaeureamid-derivate und deren herstellung
US5075337A (en) * 1989-07-26 1991-12-24 G. D. Searle & Co. Alpha-deuterated 2-alkylaminoacetamide derivatives having reduced toxicity for treatment of CNS disorders
US5153226A (en) * 1989-08-31 1992-10-06 Warner-Lambert Company Acat inhibitors for treating hypocholesterolemia
DE4102042A1 (de) * 1991-01-24 1992-07-30 Bayer Ag Substituierte aminosaeureamid-derivate deren herstellung und verwendung als fungizide
US5141960A (en) * 1991-06-25 1992-08-25 G. D. Searle & Co. Tricyclic glycinamide derivatives as anti-convulsants
GB9306886D0 (en) * 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation
GB9306899D0 (en) * 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylalkylaminobenzyl) aminopropionamide derivatives and process for their preparation
US5585358A (en) * 1993-07-06 1996-12-17 Yissum Research Development Corporation Of The Hebrew University Of Jerusalem Derivatives of valproic acid amides and 2-valproenoic acid amides, method of making and use thereof as anticonvulsant agents
IT1283489B1 (it) * 1996-07-23 1998-04-21 Chiesi Farma Spa Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
EP1064254B1 (en) * 1998-03-26 2007-10-17 University of Saskatchewan Aliphatic amino carboxylic and amino phosphonic acids, amino nitriles and amino tetrazoles as cellular rescue agents
US6984754B1 (en) 1998-03-26 2006-01-10 University Of Saskatchewan Technologies Inc. Aliphatic amino carboxylic and amino phosphonic acids amino nitriles and amino tetrazoles as cellular rescue agents
WO2000046183A1 (en) * 1999-02-08 2000-08-10 Checkpoint Genetics, Inc. N-substituted amino acids, antioxidant pharmaceutical compositions containing same and methods using same
EP1303289A4 (en) * 2000-07-21 2009-08-05 Yissum Res Dev Co USE OF VALPROIC ACID DERIVATIVES AND 2-VALPROENIC ACID AMIDES FOR THE TREATMENT OF MANIE IN CASES OF BIPOLAR DISORDER
CA2418455A1 (en) * 2000-08-17 2002-02-21 Teva Pharmaceutical Industries, Ltd. Valproic acid derivatives for the treatment of pain
US7112612B2 (en) * 2000-11-21 2006-09-26 Ucb S.A. N-alkylated GABA compounds, processes for their preparation and their use as medicaments
US20030035784A1 (en) * 2001-03-05 2003-02-20 Kao Corporation Hair cosmetic, aminocarboxylic acid amide and method for producing the same
DE60209152T2 (de) 2001-09-03 2006-08-03 Newron Pharmaceuticals S.P.A. Pharmazeutische zusammensetzung, umfassend gabapentin oder ein analogon davon und ein alpha-aminoamid
EP1438956A1 (en) * 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
RU2391973C2 (ru) * 2004-09-10 2010-06-20 Ньюрон Фармасьютикалс С.П.А. Применение (галобензилокси)бензиламино-пропанамидов для производства лекарственных средств, действующих как селективные модуляторы натриевых и/или кальциевых каналов
EP1791932A1 (en) * 2004-09-13 2007-06-06 Ciba Specialty Chemicals Holding Inc. Alkylaminoacetamide lubricant additives
FR2896991A1 (fr) * 2006-02-03 2007-08-10 Inst Nat Sante Rech Med Procede pour preparer un compose organique a l'etat solide et compositions pharmaceutiques comprenant ledit compose organique
CN102351733B (zh) * 2011-07-21 2014-03-19 凯莱英医药化学（阜新）技术有限公司 一种制备2-氨基-n,n-二甲基乙酰胺盐酸盐的方法
PL3766916T3 (pl) 2014-06-25 2023-02-27 Acuitas Therapeutics Inc. Nowe lipidy i formulacje nanocząstek lipidowych do dostarczania kwasów nukleinowych
JP6053724B2 (ja) * 2014-06-26 2016-12-27 国立大学法人九州大学 イオン交換樹脂及び金属の吸着分離方法
IL283545B2 (en) 2015-06-29 2023-09-01 Acuitas Therapeutics Inc Lipids and nanoparticulate lipid formulations for delivery of nucleic acids
HRP20230209T1 (hr) 2015-10-28 2023-04-14 Acuitas Therapeutics Inc. Novi lipidi i lipidne formulacije nanočestica za isporuku nukleinskih kiselina
CN106187829B (zh) * 2016-07-29 2017-12-15 万华化学集团股份有限公司 一种制备乙二胺基乙磺酸盐的方法
WO2018191657A1 (en) 2017-04-13 2018-10-18 Acuitas Therapeutics, Inc. Lipids for delivery of active agents
CN116693411A (zh) 2017-04-28 2023-09-05 爱康泰生治疗公司 用于递送核酸的新型羰基脂质和脂质纳米颗粒制剂
JP7355731B2 (ja) 2017-08-16 2023-10-03 アクイタス セラピューティクス インコーポレイテッド 脂質ナノ粒子製剤における使用のための脂質
US11524932B2 (en) 2017-08-17 2022-12-13 Acuitas Therapeutics, Inc. Lipids for use in lipid nanoparticle formulations
EP3668834A1 (en) * 2017-08-17 2020-06-24 Acuitas Therapeutics, Inc. Lipids for use in lipid nanoparticle formulations
US11542225B2 (en) 2017-08-17 2023-01-03 Acuitas Therapeutics, Inc. Lipids for use in lipid nanoparticle formulations
KR101953366B1 (ko) 2018-12-26 2019-02-28 정종문 침향을 포함하는 기억력 및 인지능력을 향상시키는 기능성 건강식품 및 이의 제조방법
AU2020205717A1 (en) 2019-01-11 2021-08-12 Acuitas Therapeutics, Inc. Lipids for lipid nanoparticle delivery of active agents
USD926577S1 (en) 2019-09-23 2021-08-03 Verdant Ventures Tamper-resistant lid assembly
US11326923B2 (en) 2019-10-08 2022-05-10 Verdant Ventures Tamper-resistant lid assembly for dispensing a premeasured amount of liquid
US11976019B2 (en) 2020-07-16 2024-05-07 Acuitas Therapeutics, Inc. Cationic lipids for use in lipid nanoparticles

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2511311A1 (de) 1974-03-14 1975-09-18 Sumitomo Chemical Co N-substituierte aminoacetamide, verfahren zu deren herstellung und fungizide mittel
DE2832009A1 (de) 1978-07-20 1980-01-31 Deutsches Krebsforsch Verwendung von sarkosin und sarkosinderivaten ls tumorhemmende wirksubstanzen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2368208A (en) * 1940-12-16 1945-01-30 Emulsol Corp Chemical compounds and method of preparing same
US2781385A (en) * 1953-09-21 1957-02-12 Gefgy Chemical Corp Diamidocarboxylic acids and certain salts thereof
FI41563B (sh) * 1962-05-09 1969-09-01 Ferrosan Ab

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2511311A1 (de) 1974-03-14 1975-09-18 Sumitomo Chemical Co N-substituierte aminoacetamide, verfahren zu deren herstellung und fungizide mittel
DE2832009A1 (de) 1978-07-20 1980-01-31 Deutsches Krebsforsch Verwendung von sarkosin und sarkosinderivaten ls tumorhemmende wirksubstanzen

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Beilsteins Handbuch der organischen Chemie, 4. Aufl., 4. Ergänzungswerk, Bd. 4, T. 3, Springer-Verlag, Berlin 1980, S.2384-6, 2388, 2392, 2405 *
Chemical Abstracts 80, Referat 110225, 1974 *
Chemical Abstracts 82, Referat-Nr. 172983, 1975 *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3329628A1 (de) * 1982-08-20 1984-03-22 MIDIT Société Fiduciaire, Vaduz Derivate der (omega)-aminsaeuren, deren herstellung und verwendung sowie diese derivate enthaltende zubereitungen
DE3347867A1 (sh) * 1982-08-20 1985-04-18
US5391577A (en) * 1989-05-25 1995-02-21 Farmitalia Carlo Erba S R L N-phenylalkyl substituted α-amino carboxamide derivatives and process for their preparation
US5502079A (en) * 1989-05-25 1996-03-26 Farmitalia Carlo Erba S.R.L. N-phenylalkyl substituted α-amino carboxamide derivatives and process for their preparation
WO1997045115A1 (en) * 1996-05-31 1997-12-04 Trophix Pharmaceuticals, Inc. Pharmaceutical for treatment of neurological and neuropsychiatric disorders
US6191165B1 (en) * 1996-05-31 2001-02-20 Allelix Neuroscience Inc. Pharmaceutical for treatment of neurological and neuropsychiatric disorders
US7019024B2 (en) * 1996-05-31 2006-03-28 Allelix Neuroscience Inc. Pharmaceutical for treatment of neurological and neuropsychiatric disorders
US6667336B2 (en) 2001-02-16 2003-12-23 Nps Allelix Corp. GlyT-1 inhibitors

Also Published As

Publication number Publication date
FI82033B (fi) 1990-09-28
SE453917B (sv) 1988-03-14
IL59679A0 (en) 1980-06-30
AU536499B2 (en) 1984-05-10
GB2048852A (en) 1980-12-17
ES8104790A1 (es) 1981-04-16
NL191508B (nl) 1995-04-18
FR2451913B1 (sh) 1984-07-13
CA1184567A (en) 1985-03-26
NO157817C (no) 1988-05-25
ATA154680A (de) 1986-02-15
ES490536A0 (es) 1981-04-16
IL59679A (en) 1984-11-30
AU5678480A (en) 1980-09-25
DE3050800C2 (sh) 1989-06-22
GR68005B (sh) 1981-10-26
NL8001721A (nl) 1980-09-24
GB2048852B (en) 1983-03-30
NO800830L (no) 1980-09-23
CH645091A5 (fr) 1984-09-14
FI800900A (fi) 1980-09-23
DK162714B (da) 1991-12-02
US4639468A (en) 1987-01-27
AT381302B (de) 1986-09-25
DK162714C (da) 1992-04-21
SE8002204L (sv) 1980-09-23
NO157817B (no) 1988-02-15
NL191508C (nl) 1995-08-21
DE3010599C2 (sh) 1989-03-02
PT70992A (fr) 1980-04-01
IE49751B1 (en) 1985-12-11
FR2451913A1 (fr) 1980-10-17
FI82033C (fi) 1991-01-10
DK123580A (da) 1980-09-23
IE800599L (en) 1980-09-22

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