ES8104790A1 - Procedimiento para la preparacion de derivados de la glici- namida - Google Patents
Procedimiento para la preparacion de derivados de la glici- namidaInfo
- Publication number
- ES8104790A1 ES8104790A1 ES490536A ES490536A ES8104790A1 ES 8104790 A1 ES8104790 A1 ES 8104790A1 ES 490536 A ES490536 A ES 490536A ES 490536 A ES490536 A ES 490536A ES 8104790 A1 ES8104790 A1 ES 8104790A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- linear
- ramified
- represents hydrogen
- alkyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE LA GLICINAMIDA DE FORMULA GENERAL (I). CONSISTENTE EN PREPARAR DERIVADOS DE (I), LO CUAL PUEDE CONSEGUIRSE POR DIVERSOS PROCEDIMIENTOS. ENTRE LOS METODOS DE PREPARACION PUEDE UTILIZARSE EL QUE SE PARTE DE LA AMINA DE FORMULA (II). TAMBIEN PUEDEN UTILIZARSE METODOS ALTERNATIVOS DE PREPARACION, TALES COMO POR HIDROGENOLOSIS CATALITICA DE UNA SIGNONIMINIA, O POR REACCION DE UN ALDEHIDO O AMINA CON UN ISONITRILO EN PRESENCIA DE UN ACIDO CARBOXILICO. SE TRATA DE OBTENER COMO RESULTADO FINAL COMPOSICIONES QUE CONTIENEN COMO PRINCIPIO ACTIVO, AL MENOS, UN COMPUESTO (I) Y/O UNA SAL DEL MISMO. DE APLICACION EN EL TRATAMIENTO DE DIVERSAS FORMAS DE EPILEPSIA, DISQUINESIAS, TRASTORNOS DE LA MEMORIA Y TRASTORNOS PSIQUICOS COMO LA DEPRESION. *FORMULA* C
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LU81069A LU81069A1 (fr) | 1979-03-22 | 1979-03-22 | Derive de glycinamide, preparation de ce derive, son utilisation ainsi que composition contenant ce derive |
LU81068A LU81068A1 (fr) | 1979-03-22 | 1979-03-22 | Derives de la glycinamide, leur preparation et utilisation, ainsi que compositions contenant ces derives |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8104790A1 true ES8104790A1 (es) | 1981-04-16 |
ES490536A0 ES490536A0 (es) | 1981-04-16 |
Family
ID=26640253
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES490536A Granted ES490536A0 (es) | 1979-03-22 | 1980-03-21 | Procedimiento para la preparacion de derivados de la glici- namida |
Country Status (18)
Country | Link |
---|---|
US (1) | US4639468A (es) |
AT (1) | AT381302B (es) |
AU (1) | AU536499B2 (es) |
CA (1) | CA1184567A (es) |
CH (1) | CH645091A5 (es) |
DE (2) | DE3010599A1 (es) |
DK (1) | DK162714C (es) |
ES (1) | ES490536A0 (es) |
FI (1) | FI82033C (es) |
FR (1) | FR2451913A1 (es) |
GB (1) | GB2048852B (es) |
GR (1) | GR68005B (es) |
IE (1) | IE49751B1 (es) |
IL (1) | IL59679A (es) |
NL (1) | NL191508C (es) |
NO (1) | NO157817C (es) |
PT (1) | PT70992A (es) |
SE (1) | SE453917B (es) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2937698A1 (de) * | 1979-09-18 | 1981-04-02 | A. Nattermann & Cie GmbH, 5000 Köln | N-propionylsarcosinanilide, deren herstellungsverfahren und arzneimittel auf deren basis |
FI832935A (fi) * | 1982-08-20 | 1984-02-21 | Midit | Derivat av w-aminosyror, deras framstaellning samt dessa derivat innehaollande blandningar |
US4798687A (en) * | 1987-02-06 | 1989-01-17 | Pennwalt Corporation | 2-Amino-N-[1,2-Diphenyl-1-(thifluoromethyl)ethyl]acetamide derivatives |
US4904681A (en) * | 1987-12-01 | 1990-02-27 | G. D. Searle & Co. | D-cycloserine and its prodrugs as cognitive enhancers |
US4891058A (en) * | 1988-07-18 | 1990-01-02 | Ici Americas Inc. | 1-alkyl-3-aryl imidazolidine-2,4-diones and herbicidal use |
US5278191A (en) * | 1988-08-31 | 1994-01-11 | G. D. Searle & Co. | Diphenylmethylaminoacetamide derivatives as anti-convulsants |
US5288905A (en) * | 1988-10-07 | 1994-02-22 | G. D. Searle & Co. | Glycyl urea derivatives as anti-convulsants |
US4944796A (en) * | 1988-11-14 | 1990-07-31 | Ici Americas Inc. | Certain 2-(disubstituted amino) acetanilide herbicides |
DE3915755A1 (de) * | 1989-05-13 | 1990-11-29 | Bayer Ag | Fungizide mittel sowie substituierte aminosaeureamid-derivate und deren herstellung |
IL94466A (en) * | 1989-05-25 | 1995-01-24 | Erba Carlo Spa | Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation |
US5075337A (en) * | 1989-07-26 | 1991-12-24 | G. D. Searle & Co. | Alpha-deuterated 2-alkylaminoacetamide derivatives having reduced toxicity for treatment of CNS disorders |
US5153226A (en) * | 1989-08-31 | 1992-10-06 | Warner-Lambert Company | Acat inhibitors for treating hypocholesterolemia |
DE4102042A1 (de) * | 1991-01-24 | 1992-07-30 | Bayer Ag | Substituierte aminosaeureamid-derivate deren herstellung und verwendung als fungizide |
US5141960A (en) * | 1991-06-25 | 1992-08-25 | G. D. Searle & Co. | Tricyclic glycinamide derivatives as anti-convulsants |
GB9306886D0 (en) * | 1993-04-01 | 1993-05-26 | Erba Carlo Spa | Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation |
GB9306899D0 (en) * | 1993-04-01 | 1993-05-26 | Erba Carlo Spa | Substituted (arylalkylaminobenzyl) aminopropionamide derivatives and process for their preparation |
US5585358A (en) * | 1993-07-06 | 1996-12-17 | Yissum Research Development Corporation Of The Hebrew University Of Jerusalem | Derivatives of valproic acid amides and 2-valproenoic acid amides, method of making and use thereof as anticonvulsant agents |
SK285854B6 (sk) * | 1996-05-31 | 2007-09-06 | Allelix Neuroscience Inc. | Substituovaný amín, spôsoby jeho prípravy a použitie, farmaceutický prostriedok a jeho použitie |
US6191165B1 (en) * | 1996-05-31 | 2001-02-20 | Allelix Neuroscience Inc. | Pharmaceutical for treatment of neurological and neuropsychiatric disorders |
IT1283489B1 (it) * | 1996-07-23 | 1998-04-21 | Chiesi Farma Spa | Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico |
GB9727523D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
US6984754B1 (en) | 1998-03-26 | 2006-01-10 | University Of Saskatchewan Technologies Inc. | Aliphatic amino carboxylic and amino phosphonic acids amino nitriles and amino tetrazoles as cellular rescue agents |
AU767098B2 (en) * | 1998-03-26 | 2003-10-30 | University Of Saskatchewan | Aliphatic amino carboxylic and amino phosphonic acids, amino nitriles and amino tetrazoles as cellular rescue agents |
AU2985100A (en) * | 1999-02-08 | 2000-08-25 | Checkpoint Genetics, Inc. | (n)-substituted amino acids, antioxidant pharmaceutical compositions containing same and methods using same |
WO2002007677A2 (en) * | 2000-07-21 | 2002-01-31 | Teva Pharmaceutical Industries, Ltd. | Use of derivatives of valproic acid and 2-valproenic acid amides for the treatment of mania in bipolar disorder |
DE60112766T2 (de) * | 2000-08-17 | 2006-03-30 | Teva Pharmaceutical Industries Ltd. | Verwendung von Derivaten der Valproinsäureamide und 2-Valproinsäureamide zur Behandlung und Prävention von Schmerzen und/oder Kopfschmerzen |
DE60134337D1 (de) * | 2000-11-21 | 2008-07-17 | Ucb Pharma Sa | N-alkylierte gaba verbindungen, verfahren zu deren |
ES2266446T3 (es) | 2001-02-16 | 2007-03-01 | Allelix Neuroscience Inc. | Derivados de aminas sustituidas con tiofeno como inhibidores de glyt-1. |
US20030035784A1 (en) * | 2001-03-05 | 2003-02-20 | Kao Corporation | Hair cosmetic, aminocarboxylic acid amide and method for producing the same |
AU2002333374B2 (en) | 2001-09-03 | 2007-03-22 | Newron Pharmaceuticals S.P.A. | Pharmaceutical composition comprising gabapentin or an analogue thereof and an (alpha)- aminoamide and its analgesic use |
EP1438956A1 (en) * | 2003-01-16 | 2004-07-21 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful as antimigraine agents |
CA2577408C (en) * | 2004-09-10 | 2013-07-09 | Elena Barbanti | Use of (halobenzyloxy) benzylamino-propanamides for the manufacture of medicaments active as sodium and/or calcium channel selective modulators |
WO2006029966A1 (en) * | 2004-09-13 | 2006-03-23 | Ciba Specialty Chemicals Holding Inc. | Alkylaminoacetamide lubricant additives |
FR2896991A1 (fr) * | 2006-02-03 | 2007-08-10 | Inst Nat Sante Rech Med | Procede pour preparer un compose organique a l'etat solide et compositions pharmaceutiques comprenant ledit compose organique |
CN102351733B (zh) * | 2011-07-21 | 2014-03-19 | 凯莱英医药化学(阜新)技术有限公司 | 一种制备2-氨基-n,n-二甲基乙酰胺盐酸盐的方法 |
ES2931832T3 (es) | 2014-06-25 | 2023-01-03 | Acuitas Therapeutics Inc | Lípidos y formulaciones de nanopartículas lipídicas novedosos para la entrega de ácidos nucleicos |
JP6053724B2 (ja) * | 2014-06-26 | 2016-12-27 | 国立大学法人九州大学 | イオン交換樹脂及び金属の吸着分離方法 |
US10221127B2 (en) | 2015-06-29 | 2019-03-05 | Acuitas Therapeutics, Inc. | Lipids and lipid nanoparticle formulations for delivery of nucleic acids |
CA3003055C (en) | 2015-10-28 | 2023-08-01 | Acuitas Therapeutics, Inc. | Lipids and lipid nanoparticle formulations for delivery of nucleic acids |
CN106187829B (zh) * | 2016-07-29 | 2017-12-15 | 万华化学集团股份有限公司 | 一种制备乙二胺基乙磺酸盐的方法 |
WO2018191657A1 (en) | 2017-04-13 | 2018-10-18 | Acuitas Therapeutics, Inc. | Lipids for delivery of active agents |
ES2981244T3 (es) | 2017-04-28 | 2024-10-07 | Acuitas Therapeutics Inc | Novedosas formulaciones de nanopartículas de lípidos de carbonilo y lípidos para la administración de ácidos nucleicos |
US11639329B2 (en) | 2017-08-16 | 2023-05-02 | Acuitas Therapeutics, Inc. | Lipids for use in lipid nanoparticle formulations |
WO2019036030A1 (en) | 2017-08-17 | 2019-02-21 | Acuitas Therapeutics, Inc. | LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS |
WO2019036028A1 (en) | 2017-08-17 | 2019-02-21 | Acuitas Therapeutics, Inc. | LIPIDS FOR USE IN LIPID NANOPARTICULAR FORMULATIONS |
EP3668834B1 (en) | 2017-08-17 | 2024-10-02 | Acuitas Therapeutics, Inc. | Lipids for use in lipid nanoparticle formulations |
KR101953366B1 (ko) | 2018-12-26 | 2019-02-28 | 정종문 | 침향을 포함하는 기억력 및 인지능력을 향상시키는 기능성 건강식품 및 이의 제조방법 |
JP7523449B2 (ja) | 2019-01-11 | 2024-07-26 | アクイタス セラピューティクス インコーポレイテッド | 活性剤の脂質ナノ粒子送達のための脂質 |
USD926577S1 (en) | 2019-09-23 | 2021-08-03 | Verdant Ventures | Tamper-resistant lid assembly |
US11326923B2 (en) | 2019-10-08 | 2022-05-10 | Verdant Ventures | Tamper-resistant lid assembly for dispensing a premeasured amount of liquid |
US11976019B2 (en) | 2020-07-16 | 2024-05-07 | Acuitas Therapeutics, Inc. | Cationic lipids for use in lipid nanoparticles |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2368208A (en) * | 1940-12-16 | 1945-01-30 | Emulsol Corp | Chemical compounds and method of preparing same |
US2781385A (en) * | 1953-09-21 | 1957-02-12 | Gefgy Chemical Corp | Diamidocarboxylic acids and certain salts thereof |
LU43649A1 (es) * | 1962-05-09 | 1963-07-16 | ||
JPS5319654B2 (es) | 1974-03-14 | 1978-06-22 | ||
DE2832009A1 (de) | 1978-07-20 | 1980-01-31 | Deutsches Krebsforsch | Verwendung von sarkosin und sarkosinderivaten ls tumorhemmende wirksubstanzen |
-
1980
- 1980-03-20 DE DE19803010599 patent/DE3010599A1/de active Granted
- 1980-03-20 DE DE3050800A patent/DE3050800C2/de not_active Expired
- 1980-03-21 PT PT70992A patent/PT70992A/pt active IP Right Revival
- 1980-03-21 AT AT0154680A patent/AT381302B/de not_active IP Right Cessation
- 1980-03-21 FR FR8006390A patent/FR2451913A1/fr active Granted
- 1980-03-21 FI FI800900A patent/FI82033C/fi not_active IP Right Cessation
- 1980-03-21 NO NO800830A patent/NO157817C/no unknown
- 1980-03-21 CH CH225380A patent/CH645091A5/fr not_active IP Right Cessation
- 1980-03-21 DK DK123580A patent/DK162714C/da not_active IP Right Cessation
- 1980-03-21 ES ES490536A patent/ES490536A0/es active Granted
- 1980-03-21 IL IL59679A patent/IL59679A/xx unknown
- 1980-03-21 SE SE8002204A patent/SE453917B/sv not_active IP Right Cessation
- 1980-03-22 GR GR61512A patent/GR68005B/el unknown
- 1980-03-24 AU AU56784/80A patent/AU536499B2/en not_active Expired
- 1980-03-24 CA CA000348319A patent/CA1184567A/en not_active Expired
- 1980-03-24 NL NL8001721A patent/NL191508C/xx not_active IP Right Cessation
- 1980-03-24 GB GB8009801A patent/GB2048852B/en not_active Expired
- 1980-03-24 IE IE599/80A patent/IE49751B1/en not_active IP Right Cessation
-
1985
- 1985-08-23 US US06/768,185 patent/US4639468A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU5678480A (en) | 1980-09-25 |
IE49751B1 (en) | 1985-12-11 |
US4639468A (en) | 1987-01-27 |
PT70992A (fr) | 1980-04-01 |
GR68005B (es) | 1981-10-26 |
NL8001721A (nl) | 1980-09-24 |
NL191508C (nl) | 1995-08-21 |
IL59679A0 (en) | 1980-06-30 |
DE3050800C2 (es) | 1989-06-22 |
DE3010599C2 (es) | 1989-03-02 |
NO800830L (no) | 1980-09-23 |
DE3010599A1 (de) | 1980-10-09 |
GB2048852B (en) | 1983-03-30 |
ATA154680A (de) | 1986-02-15 |
ES490536A0 (es) | 1981-04-16 |
NO157817C (no) | 1988-05-25 |
DK162714B (da) | 1991-12-02 |
NL191508B (nl) | 1995-04-18 |
FR2451913A1 (fr) | 1980-10-17 |
FI800900A (fi) | 1980-09-23 |
IL59679A (en) | 1984-11-30 |
GB2048852A (en) | 1980-12-17 |
AT381302B (de) | 1986-09-25 |
AU536499B2 (en) | 1984-05-10 |
CA1184567A (en) | 1985-03-26 |
FI82033C (fi) | 1991-01-10 |
SE8002204L (sv) | 1980-09-23 |
FR2451913B1 (es) | 1984-07-13 |
DK123580A (da) | 1980-09-23 |
IE800599L (en) | 1980-09-22 |
NO157817B (no) | 1988-02-15 |
CH645091A5 (fr) | 1984-09-14 |
DK162714C (da) | 1992-04-21 |
FI82033B (fi) | 1990-09-28 |
SE453917B (sv) | 1988-03-14 |
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