DE2848965A1 - Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine - Google Patents

Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine

Info

Publication number
DE2848965A1
DE2848965A1 DE19782848965 DE2848965A DE2848965A1 DE 2848965 A1 DE2848965 A1 DE 2848965A1 DE 19782848965 DE19782848965 DE 19782848965 DE 2848965 A DE2848965 A DE 2848965A DE 2848965 A1 DE2848965 A1 DE 2848965A1
Authority
DE
Germany
Prior art keywords
neisseria meningitidis
membrane proteins
detergent
minutes
vaccine containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19782848965
Other languages
German (de)
English (en)
Inventor
Gerhard Dipl Chem Guthoehrlein
Torsten Bertil Dr Helting
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Priority to DE19782848965 priority Critical patent/DE2848965A1/de
Priority to ES485715A priority patent/ES485715A1/es
Priority to AT79104391T priority patent/ATE857T1/de
Priority to EP79104391A priority patent/EP0011243B1/de
Priority to DE7979104391T priority patent/DE2962526D1/de
Priority to IL58673A priority patent/IL58673A/xx
Priority to JP14456179A priority patent/JPS5566519A/ja
Priority to MX10131579U priority patent/MX5941E/es
Priority to CA000339541A priority patent/CA1142083A/en
Priority to AU52682/79A priority patent/AU533386B2/en
Priority to DK475779A priority patent/DK154841C/da
Publication of DE2848965A1 publication Critical patent/DE2848965A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE19782848965 1978-11-11 1978-11-11 Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine Withdrawn DE2848965A1 (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
DE19782848965 DE2848965A1 (de) 1978-11-11 1978-11-11 Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine
ES485715A ES485715A1 (es) 1978-11-11 1979-11-06 Procedimiento mejorado para la preparacion de proteinas de membranas
AT79104391T ATE857T1 (de) 1978-11-11 1979-11-08 Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine.
EP79104391A EP0011243B1 (de) 1978-11-11 1979-11-08 Verfahren zur Herstellung von Membranproteinen aus Neisseria meningitidis und diese enthaltende Vaccine
DE7979104391T DE2962526D1 (en) 1978-11-11 1979-11-08 Process for preparing membrane proteins from neisseria meningitidis and vaccines containing them
IL58673A IL58673A (en) 1978-11-11 1979-11-09 Process for the isolation of membrane proteins from neisseria meningitidis and vaccines containing same
JP14456179A JPS5566519A (en) 1978-11-11 1979-11-09 Manufacture of membrane protein and vaccine containing it
MX10131579U MX5941E (es) 1978-11-11 1979-11-09 Procedimiento mejorado para la preparacion de membranoproteinas a partir de neisseria meningitidis grupo"b"
CA000339541A CA1142083A (en) 1978-11-11 1979-11-09 Process for the isolation of membrane proteins from neisseria meningitidis and vaccines containing same
AU52682/79A AU533386B2 (en) 1978-11-11 1979-11-09 Isolation of membrane proteins from neisseria meningitidis and vaccines containing same
DK475779A DK154841C (da) 1978-11-11 1979-11-09 Fremgangsmaade til fremstilling af membranproteiner ud fra neisseria meningitidis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782848965 DE2848965A1 (de) 1978-11-11 1978-11-11 Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine

Publications (1)

Publication Number Publication Date
DE2848965A1 true DE2848965A1 (de) 1980-05-22

Family

ID=6054405

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19782848965 Withdrawn DE2848965A1 (de) 1978-11-11 1978-11-11 Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine
DE7979104391T Expired DE2962526D1 (en) 1978-11-11 1979-11-08 Process for preparing membrane proteins from neisseria meningitidis and vaccines containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE7979104391T Expired DE2962526D1 (en) 1978-11-11 1979-11-08 Process for preparing membrane proteins from neisseria meningitidis and vaccines containing them

Country Status (9)

Country Link
EP (1) EP0011243B1 (cg-RX-API-DMAC7.html)
JP (1) JPS5566519A (cg-RX-API-DMAC7.html)
AT (1) ATE857T1 (cg-RX-API-DMAC7.html)
AU (1) AU533386B2 (cg-RX-API-DMAC7.html)
CA (1) CA1142083A (cg-RX-API-DMAC7.html)
DE (2) DE2848965A1 (cg-RX-API-DMAC7.html)
DK (1) DK154841C (cg-RX-API-DMAC7.html)
ES (1) ES485715A1 (cg-RX-API-DMAC7.html)
IL (1) IL58673A (cg-RX-API-DMAC7.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4317811A (en) 1980-09-11 1982-03-02 Merck & Co., Inc. Herpes simplex type 1 subunit vaccine
US12109243B2 (en) 2017-09-08 2024-10-08 Evelo Biosciences, Inc. Bacterial extracellular vesicles

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH074267B1 (cg-RX-API-DMAC7.html) * 1982-12-02 1995-01-25 Univ Rockefeller
US7118757B1 (en) 1988-12-19 2006-10-10 Wyeth Holdings Corporation Meningococcal class 1 outer-membrane protein vaccine
BR9910749A (pt) 1998-05-29 2001-02-13 Chiron Corp Composições e vacinas imunogênicas combinadas para meningites b e c e método de induzir uma resposta imune por administração da mesma
NZ528254A (en) 1999-05-19 2005-07-29 Chiron S Combined neisserial compositions
GB9918319D0 (en) 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
GB9928196D0 (en) 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
US8273360B2 (en) 2000-01-17 2012-09-25 Novartis Ag Outer membrane vesicle (OMV) vaccine comprising N. meningitidis serogroup B outer membrane proteins
GB0103171D0 (en) * 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
DK2255826T3 (en) 2002-08-02 2016-06-20 Glaxosmithkline Biologicals Sa Neisserial vaccine compositions comprising a combination of antigens.
GB0220194D0 (en) 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
CU23313A1 (es) 2002-11-27 2008-09-25 Inst Finlay Ct De Investigacia Mã0/00todo de obtenciã"n de estructuras cocleares. composiciones vacunales y adyuvantes basados en estructuras cocleares y sus intermediarios
GB0316560D0 (en) 2003-07-15 2003-08-20 Chiron Srl Vesicle filtration
EP1706481A2 (en) * 2003-12-23 2006-10-04 GlaxoSmithKline Biologicals S.A. Vaccine
GB0419627D0 (en) 2004-09-03 2004-10-06 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
ES2390291T3 (es) 2006-06-12 2012-11-08 Glaxosmithkline Biologicals S.A. Vacunas LOS L3V
NZ584683A (en) 2007-10-19 2012-05-25 Novartis Ag Neisseria meningitidis serogroup B vaccine formulations
ES2532946T3 (es) 2008-02-21 2015-04-06 Novartis Ag Polipéptidos PUfH meningocócicos
GB0822634D0 (en) 2008-12-11 2009-01-21 Novartis Ag Meningitis vaccines
CA2747340A1 (en) 2008-12-17 2010-06-24 Novartis Ag Meningococcal vaccines including hemoglobin receptor
AU2010258677B2 (en) 2009-06-10 2016-10-06 Glaxosmithkline Biologicals S.A. Benzonaphthyridine-containing vaccines
JP2013502918A (ja) 2009-08-27 2013-01-31 ノバルティス アーゲー 髄膜炎菌ｆＨＢＰ配列を含むハイブリッドポリペプチド
JP2013503148A (ja) 2009-08-27 2013-01-31 ノバルティス アーゲー アルミニウム、オリゴヌクレオチドおよびポリカチオンを含むアジュバント
TWI445708B (zh) 2009-09-02 2014-07-21 Irm Llc 作為ｔｌｒ活性調節劑之化合物及組合物
GB0917003D0 (en) 2009-09-28 2009-11-11 Novartis Vaccines Inst For Global Health Srl Purification of bacterial vesicles
CN102724988B (zh) 2009-09-30 2014-09-10 诺华股份有限公司 脑膜炎球菌fHBP多肽的表达
CA2779816A1 (en) 2009-10-27 2011-05-05 Novartis Ag Modified meningococcal fhbp polypeptides
WO2011057148A1 (en) 2009-11-05 2011-05-12 Irm Llc Compounds and compositions as tlr-7 activity modulators
CA2784580A1 (en) 2009-12-15 2011-07-14 Novartis Ag Homogeneous suspension of immunopotentiating compounds and uses thereof
CA2792683A1 (en) 2010-03-10 2011-09-15 Glaxosmithkline Biologicals S.A. Neisserial fhbp vaccine composition
AU2011288203A1 (en) 2010-03-18 2012-08-23 Novartis Ag Adjuvanted vaccines for serogroup B meningococcus
CA2792938C (en) 2010-03-23 2018-07-31 Irm Llc Compounds (cystein based lipopeptides) and compositions as tlr2 agonists used for treating infections, inflammations, respiratory diseases etc.
US9259462B2 (en) 2010-09-10 2016-02-16 Glaxosmithkline Biologicals Sa Developments in meningococcal outer membrane vesicles
GB201015132D0 (en) 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
US20150147356A1 (en) 2011-05-12 2015-05-28 Alan Kimura Antipyretics to enhance tolerability of vesicle-based vaccines
WO2013113917A1 (en) 2012-02-02 2013-08-08 Novartis Ag Promoters for increased protein expression in meningococcus
US10598666B2 (en) 2012-03-08 2020-03-24 Glaxosmithkline Biologicals Sa In vitro potency assay for protein-based meningococcal vaccines
JP2015521595A (ja) 2012-06-14 2015-07-30 ノバルティス アーゲー 血清群ｘ髄膜炎菌のためのワクチン
RU2015106930A (ru) 2012-09-06 2016-10-20 Новартис Аг Комбинированные вакцины с менингококком серогруппы в и к/д/с
US9764027B2 (en) 2012-09-18 2017-09-19 Glaxosmithkline Biologicals Sa Outer membrane vesicles
US10392424B2 (en) 2014-02-28 2019-08-27 Glaxosmithkline Biologicals Sa Modified meningococcal fHbp polypeptides
AU2017321039B2 (en) 2016-09-02 2021-03-18 Glaxosmithkline Biologicals Sa Vaccines for Neisseria gonorrhoeae
EP3607967A1 (en) 2018-08-09 2020-02-12 GlaxoSmithKline Biologicals S.A. Modified meningococcal fhbp polypeptides
KR102852282B1 (ko) 2018-11-06 2025-09-01 글락소스미스클라인 바이오로지칼즈 에스.에이. 면역원성 조성물
EP3799884A1 (en) 2019-10-01 2021-04-07 GlaxoSmithKline Biologicals S.A. Immunogenic compositions
GB202115077D0 (en) 2021-10-21 2021-12-08 Glaxosmithkline Biologicals Sa Assay
GB202115072D0 (en) 2021-10-21 2021-12-08 Glaxosmithkline Biologicals Sa Assay
GB202211033D0 (en) 2022-07-28 2022-09-14 Glaxosmithkline Biologicals Sa Purification process

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4317811A (en) 1980-09-11 1982-03-02 Merck & Co., Inc. Herpes simplex type 1 subunit vaccine
US12109243B2 (en) 2017-09-08 2024-10-08 Evelo Biosciences, Inc. Bacterial extracellular vesicles

Also Published As

Publication number Publication date
CA1142083A (en) 1983-03-01
DK154841B (da) 1988-12-27
EP0011243B1 (de) 1982-04-14
EP0011243A1 (de) 1980-05-28
DE2962526D1 (en) 1982-05-27
IL58673A (en) 1983-02-23
ATE857T1 (de) 1982-04-15
AU533386B2 (en) 1983-11-24
JPS6350332B2 (cg-RX-API-DMAC7.html) 1988-10-07
IL58673A0 (en) 1980-02-29
DK475779A (da) 1980-05-12
ES485715A1 (es) 1980-05-16
AU5268279A (en) 1980-05-15
DK154841C (da) 1989-06-05
JPS5566519A (en) 1980-05-20

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