DE2848965A1 - Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine - Google Patents

Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine

Info

Publication number
DE2848965A1
DE2848965A1 DE19782848965 DE2848965A DE2848965A1 DE 2848965 A1 DE2848965 A1 DE 2848965A1 DE 19782848965 DE19782848965 DE 19782848965 DE 2848965 A DE2848965 A DE 2848965A DE 2848965 A1 DE2848965 A1 DE 2848965A1
Authority
DE
Germany
Prior art keywords
neisseria meningitidis
membrane proteins
detergent
minutes
vaccine containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19782848965
Other languages
German (de)
English (en)
Inventor
Gerhard Dipl Chem Guthoehrlein
Torsten Bertil Dr Helting
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Priority to DE19782848965 priority Critical patent/DE2848965A1/de
Priority to ES485715A priority patent/ES485715A1/es
Priority to DE7979104391T priority patent/DE2962526D1/de
Priority to AT79104391T priority patent/ATE857T1/de
Priority to EP79104391A priority patent/EP0011243B1/de
Priority to AU52682/79A priority patent/AU533386B2/en
Priority to MX10131579U priority patent/MX5941E/es
Priority to DK475779A priority patent/DK154841C/da
Priority to JP14456179A priority patent/JPS5566519A/ja
Priority to IL58673A priority patent/IL58673A/xx
Priority to CA000339541A priority patent/CA1142083A/en
Publication of DE2848965A1 publication Critical patent/DE2848965A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE19782848965 1978-11-11 1978-11-11 Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine Withdrawn DE2848965A1 (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
DE19782848965 DE2848965A1 (de) 1978-11-11 1978-11-11 Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine
ES485715A ES485715A1 (es) 1978-11-11 1979-11-06 Procedimiento mejorado para la preparacion de proteinas de membranas
DE7979104391T DE2962526D1 (en) 1978-11-11 1979-11-08 Process for preparing membrane proteins from neisseria meningitidis and vaccines containing them
AT79104391T ATE857T1 (de) 1978-11-11 1979-11-08 Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine.
EP79104391A EP0011243B1 (de) 1978-11-11 1979-11-08 Verfahren zur Herstellung von Membranproteinen aus Neisseria meningitidis und diese enthaltende Vaccine
AU52682/79A AU533386B2 (en) 1978-11-11 1979-11-09 Isolation of membrane proteins from neisseria meningitidis and vaccines containing same
MX10131579U MX5941E (es) 1978-11-11 1979-11-09 Procedimiento mejorado para la preparacion de membranoproteinas a partir de neisseria meningitidis grupo"b"
DK475779A DK154841C (da) 1978-11-11 1979-11-09 Fremgangsmaade til fremstilling af membranproteiner ud fra neisseria meningitidis
JP14456179A JPS5566519A (en) 1978-11-11 1979-11-09 Manufacture of membrane protein and vaccine containing it
IL58673A IL58673A (en) 1978-11-11 1979-11-09 Process for the isolation of membrane proteins from neisseria meningitidis and vaccines containing same
CA000339541A CA1142083A (en) 1978-11-11 1979-11-09 Process for the isolation of membrane proteins from neisseria meningitidis and vaccines containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782848965 DE2848965A1 (de) 1978-11-11 1978-11-11 Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine

Publications (1)

Publication Number Publication Date
DE2848965A1 true DE2848965A1 (de) 1980-05-22

Family

ID=6054405

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19782848965 Withdrawn DE2848965A1 (de) 1978-11-11 1978-11-11 Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine
DE7979104391T Expired DE2962526D1 (en) 1978-11-11 1979-11-08 Process for preparing membrane proteins from neisseria meningitidis and vaccines containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE7979104391T Expired DE2962526D1 (en) 1978-11-11 1979-11-08 Process for preparing membrane proteins from neisseria meningitidis and vaccines containing them

Country Status (9)

Country Link
EP (1) EP0011243B1 (OSRAM)
JP (1) JPS5566519A (OSRAM)
AT (1) ATE857T1 (OSRAM)
AU (1) AU533386B2 (OSRAM)
CA (1) CA1142083A (OSRAM)
DE (2) DE2848965A1 (OSRAM)
DK (1) DK154841C (OSRAM)
ES (1) ES485715A1 (OSRAM)
IL (1) IL58673A (OSRAM)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4317811A (en) 1980-09-11 1982-03-02 Merck & Co., Inc. Herpes simplex type 1 subunit vaccine
US12109243B2 (en) 2017-09-08 2024-10-08 Evelo Biosciences, Inc. Bacterial extracellular vesicles

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU563317B2 (en) * 1982-12-02 1987-07-02 Rockefeller University, The Iga binding antibody
US7118757B1 (en) 1988-12-19 2006-10-10 Wyeth Holdings Corporation Meningococcal class 1 outer-membrane protein vaccine
ES2278446T3 (es) 1998-05-29 2007-08-01 Novartis Vaccines And Diagnostics, Inc. Vacunas combinadas b/c contra la meningitis.
EP1860191A3 (en) 1999-05-19 2008-02-13 Novartis Vaccines and Diagnostics S.r.l. Combination neisserial compositions
GB9918319D0 (en) 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
GB9928196D0 (en) 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
EP2275129A3 (en) 2000-01-17 2013-11-06 Novartis Vaccines and Diagnostics S.r.l. Outer membrane vesicle (OMV) vaccine comprising N. meningitidis serogroup B outer membrane proteins
GB0103171D0 (en) * 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
DK2255826T3 (en) 2002-08-02 2016-06-20 Glaxosmithkline Biologicals Sa Neisserial vaccine compositions comprising a combination of antigens.
GB0220194D0 (en) 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
CU23313A1 (es) 2002-11-27 2008-09-25 Inst Finlay Ct De Investigacia Mã0/00todo de obtenciã"n de estructuras cocleares. composiciones vacunales y adyuvantes basados en estructuras cocleares y sus intermediarios
GB0316560D0 (en) 2003-07-15 2003-08-20 Chiron Srl Vesicle filtration
US7628995B2 (en) * 2003-12-23 2009-12-08 Glaxosmithkline Biologicals S.A. Outer membrane vesicles and uses thereof
GB0419627D0 (en) 2004-09-03 2004-10-06 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
US20090246224A1 (en) 2006-06-12 2009-10-01 Nathalie Devos Vaccine
NZ584683A (en) 2007-10-19 2012-05-25 Novartis Ag Neisseria meningitidis serogroup B vaccine formulations
US9579372B2 (en) 2008-02-21 2017-02-28 Glaxosmithkline Biologicals Sa Meningococcal fHBP polypeptides
GB0822634D0 (en) 2008-12-11 2009-01-21 Novartis Ag Meningitis vaccines
BRPI0923006A2 (pt) 2008-12-17 2016-03-08 Novartis Ag vacinas meningococicas incluindo receptor de hemoglobina
CN102762226A (zh) 2009-06-10 2012-10-31 诺华有限公司 含苯并萘啶的疫苗
CN102740882A (zh) 2009-08-27 2012-10-17 诺华有限公司 含有铝、寡核苷酸和聚阳离子的佐剂
BR112012004275A2 (pt) 2009-08-27 2016-11-16 Novartis Ag polipeptídios híbridos incluindo sequências meningocócicas de fhbp
JO3257B1 (ar) 2009-09-02 2018-09-16 Novartis Ag مركبات وتركيبات كمعدلات لفاعلية tlr
GB0917003D0 (en) 2009-09-28 2009-11-11 Novartis Vaccines Inst For Global Health Srl Purification of bacterial vesicles
WO2011039631A2 (en) 2009-09-30 2011-04-07 Novartis Ag Expression of meningococcal fhbp polypeptides
EP2493499A1 (en) 2009-10-27 2012-09-05 Novartis AG Modified meningococcal fhbp polypeptides
WO2011057148A1 (en) 2009-11-05 2011-05-12 Irm Llc Compounds and compositions as tlr-7 activity modulators
US9408907B2 (en) 2009-12-15 2016-08-09 Glaxosmithkline Biologicals Sa Homogenous suspension of immunopotentiating compounds and uses thereof
JP2013521326A (ja) 2010-03-10 2013-06-10 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 免疫原性組成物
WO2012020326A1 (en) 2010-03-18 2012-02-16 Novartis Ag Adjuvanted vaccines for serogroup b meningococcus
JP5848748B2 (ja) 2010-03-23 2016-01-27 アイアールエム・リミテッド・ライアビリティ・カンパニーＩｒｍ，Ｌｌｃ 感染症、炎症、呼吸器疾患などの処置に使用するｔｌｒ２アゴニストとしての化合物（システインベースのリポペプチド）および組成物
AU2011300418B2 (en) 2010-09-10 2016-05-12 Glaxosmithkline Biologicals Sa Meningococcus overexpressing NadA and/or NHBA and outer membrane vesicles derived therefrom
GB201015132D0 (en) 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
WO2012153302A1 (en) 2011-05-12 2012-11-15 Novartis Ag Antipyretics to enhance tolerability of vesicle-based vaccines
MX2014008988A (es) 2012-02-02 2014-08-27 Novartis Ag Promotores para aumento de expresion de proteinas en meningococo.
US10598666B2 (en) 2012-03-08 2020-03-24 Glaxosmithkline Biologicals Sa In vitro potency assay for protein-based meningococcal vaccines
US10376573B2 (en) 2012-06-14 2019-08-13 Glaxosmithkline Biologicals Sa Vaccines for serogroup X meningococcus
RU2015106930A (ru) 2012-09-06 2016-10-20 Новартис Аг Комбинированные вакцины с менингококком серогруппы в и к/д/с
RU2662970C2 (ru) 2012-09-18 2018-07-31 Новартис Аг Везикулы наружной мембраны
CA2940447C (en) 2014-02-28 2023-07-11 Glaxosmithkline Biologicals Sa Modified meningococcal fhbp polypeptides
JP7104027B2 (ja) 2016-09-02 2022-07-20 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 淋菌に対するワクチン
EP3607967A1 (en) 2018-08-09 2020-02-12 GlaxoSmithKline Biologicals S.A. Modified meningococcal fhbp polypeptides
AU2019376832B2 (en) 2018-11-06 2024-01-25 Glaxosmithkline Biologicals Sa Immunogenic compositions
EP3799884A1 (en) 2019-10-01 2021-04-07 GlaxoSmithKline Biologicals S.A. Immunogenic compositions
GB202115077D0 (en) 2021-10-21 2021-12-08 Glaxosmithkline Biologicals Sa Assay
GB202115072D0 (en) 2021-10-21 2021-12-08 Glaxosmithkline Biologicals Sa Assay
GB202211033D0 (en) 2022-07-28 2022-09-14 Glaxosmithkline Biologicals Sa Purification process

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4317811A (en) 1980-09-11 1982-03-02 Merck & Co., Inc. Herpes simplex type 1 subunit vaccine
US12109243B2 (en) 2017-09-08 2024-10-08 Evelo Biosciences, Inc. Bacterial extracellular vesicles

Also Published As

Publication number Publication date
DE2962526D1 (en) 1982-05-27
EP0011243B1 (de) 1982-04-14
IL58673A (en) 1983-02-23
ATE857T1 (de) 1982-04-15
DK154841C (da) 1989-06-05
AU533386B2 (en) 1983-11-24
DK475779A (da) 1980-05-12
AU5268279A (en) 1980-05-15
IL58673A0 (en) 1980-02-29
CA1142083A (en) 1983-03-01
EP0011243A1 (de) 1980-05-28
JPS5566519A (en) 1980-05-20
ES485715A1 (es) 1980-05-16
JPS6350332B2 (OSRAM) 1988-10-07
DK154841B (da) 1988-12-27

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