DE2548340C2 - - Google Patents
Info
- Publication number
- DE2548340C2 DE2548340C2 DE2548340A DE2548340A DE2548340C2 DE 2548340 C2 DE2548340 C2 DE 2548340C2 DE 2548340 A DE2548340 A DE 2548340A DE 2548340 A DE2548340 A DE 2548340A DE 2548340 C2 DE2548340 C2 DE 2548340C2
- Authority
- DE
- Germany
- Prior art keywords
- group
- benzimidazole
- groups
- compound
- general formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Priority Applications (28)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7406513A SE416649B (sv) | 1974-05-16 | 1974-05-16 | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
FI752327A FI63756C (fi) | 1974-05-16 | 1975-08-15 | Foerfarande foer framstaellning av 2-(2-pyridylmetylsulfinyl)-bensimidazolderivat med magsyrasekretionsinhiberande verkan |
NO75752851A NO143222C (no) | 1974-05-16 | 1975-08-15 | Analogifremgangsmaate for fremstilling av nye substituerte pyridylsulfinyl-benzimidazoler med terapeutisk aktivitet |
DK372175AA DK140840B (da) | 1974-05-16 | 1975-08-18 | Analogifremgangsmåde til fremstilling af benzimidazolderivater eller syreadditionssalte deraf. |
ZA00756600A ZA756600B (en) | 1974-05-16 | 1975-10-20 | Gastric acid secretion agents |
CY1125A CY1125A (en) | 1974-05-16 | 1975-10-20 | 2-(heterocaclic asbstituted alkylsulphinyl)-benzinmidazoles and their pharmaceutical compositions |
GB43039/75A GB1525958A (en) | 1974-05-16 | 1975-10-20 | 2-(heterocyclic substituted alkylsulphinyl)-benzimidazoles and their pharmaceutical compositions |
IE2313/75A IE42451B1 (en) | 1974-05-16 | 1975-10-23 | 2-(heterocyclic substituted alkylsulphinyl)-benzimidazoles and their pharmaceutical compositions |
DE19752548340 DE2548340A1 (de) | 1974-05-16 | 1975-10-29 | Benzimidazole, verfahren zu deren herstellung und sie enthaltende mittel |
AT838075A AT337697B (de) | 1974-05-16 | 1975-11-04 | Verfahren zur herstellung von neuen benzimidazolderivaten und ihren salzen |
CS757458A CS196289B2 (en) | 1974-05-16 | 1975-11-05 | Process for preparing new compounds |
NL7513141A NL7513141A (nl) | 1974-05-16 | 1975-11-10 | Benzimidazoolderivaten en werkwijze voor het be- reiden daarvan alsmede preparaten voor het bein- vloeden van de maagzuursecretie. |
US05/630,916 US4045563A (en) | 1974-05-16 | 1975-11-11 | Substituted 2-[pyridylalkylenesulfinyl]-benzimidazoles with gastric acid secretion inhibiting effects |
HU75HE00000696A HU172653B (hu) | 1974-05-16 | 1975-11-12 | Sposob poluchenija zamehhennykh 2-skobka-2-piridil-metil-sul'finil-skobka zakryta-benzimidazolov |
SU752189960A SU602118A3 (ru) | 1974-05-16 | 1975-11-13 | Способ получени производных бензимидазола или их солей |
DD189463A DD122534A5 (US06897227-20050524-C00065.png) | 1974-05-16 | 1975-11-14 | |
FR7534910A FR2331340A1 (fr) | 1974-05-16 | 1975-11-14 | Nouveaux derives du benzimidazole, procede pour leur obtention et compositions pharmaceutiques les contenant |
CA239,643A CA1055033A (en) | 1974-05-16 | 1975-11-14 | 2-(2-heterocyclic-methylsulphinyl)-benzimidazole compounds |
CH1481475A CH623814A5 (en) | 1974-05-16 | 1975-11-14 | Process for the preparation of novel benzimidazoles |
JP50137712A JPS5262275A (en) | 1974-05-16 | 1975-11-15 | Production of organic compound |
FR7616732A FR2392021A1 (fr) | 1974-05-16 | 1976-06-03 | Nouveaux derives du benzimidazole et procede pour leur obtention |
AT752276A AT351524B (de) | 1974-05-16 | 1976-10-11 | Verfahren zur herstellung von neuen benzimida- zolderivaten, ihren salzen und optischen isomeren |
DK783659A DK365978A (da) | 1974-05-16 | 1978-08-18 | Mellemprodukt til anvendelse ved fremstilling af benzimidazolderivater |
CS786886A CS196290B2 (en) | 1974-05-16 | 1978-10-23 | Process for preparing new compounds |
CH976079A CH623582A5 (en) | 1974-05-16 | 1979-10-31 | Process for the preparation of benzimidazoles |
FI811747A FI65617C (fi) | 1974-05-16 | 1981-06-04 | Mellanprodukt foer framstaellning av magsyrasekretionsinhiberande 2-(2-pyridylmetylsulfinyl)-benzimidazolderivat |
HK87/82A HK8782A (en) | 1974-05-16 | 1982-02-25 | 2-(heterocyclic substituted alkylsulphinyl)-benzimidazoles and their pharmaceutical compositions |
MY159/82A MY8200159A (en) | 1974-05-16 | 1982-12-30 | 2-[heterocylic substituted alkylsulphinyl]-benzimidazoles and their pharmaceutical compositions |
Applications Claiming Priority (25)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7406513A SE416649B (sv) | 1974-05-16 | 1974-05-16 | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
FI752327A FI63756C (fi) | 1974-05-16 | 1975-08-15 | Foerfarande foer framstaellning av 2-(2-pyridylmetylsulfinyl)-bensimidazolderivat med magsyrasekretionsinhiberande verkan |
NO75752851A NO143222C (no) | 1974-05-16 | 1975-08-15 | Analogifremgangsmaate for fremstilling av nye substituerte pyridylsulfinyl-benzimidazoler med terapeutisk aktivitet |
DK372175AA DK140840B (da) | 1974-05-16 | 1975-08-18 | Analogifremgangsmåde til fremstilling af benzimidazolderivater eller syreadditionssalte deraf. |
GB43039/75A GB1525958A (en) | 1974-05-16 | 1975-10-20 | 2-(heterocyclic substituted alkylsulphinyl)-benzimidazoles and their pharmaceutical compositions |
ZA00756600A ZA756600B (en) | 1974-05-16 | 1975-10-20 | Gastric acid secretion agents |
IE2313/75A IE42451B1 (en) | 1974-05-16 | 1975-10-23 | 2-(heterocyclic substituted alkylsulphinyl)-benzimidazoles and their pharmaceutical compositions |
DE19752548340 DE2548340A1 (de) | 1974-05-16 | 1975-10-29 | Benzimidazole, verfahren zu deren herstellung und sie enthaltende mittel |
AT838075A AT337697B (de) | 1974-05-16 | 1975-11-04 | Verfahren zur herstellung von neuen benzimidazolderivaten und ihren salzen |
CS757458A CS196289B2 (en) | 1974-05-16 | 1975-11-05 | Process for preparing new compounds |
NL7513141A NL7513141A (nl) | 1974-05-16 | 1975-11-10 | Benzimidazoolderivaten en werkwijze voor het be- reiden daarvan alsmede preparaten voor het bein- vloeden van de maagzuursecretie. |
US05/630,916 US4045563A (en) | 1974-05-16 | 1975-11-11 | Substituted 2-[pyridylalkylenesulfinyl]-benzimidazoles with gastric acid secretion inhibiting effects |
HU75HE00000696A HU172653B (hu) | 1974-05-16 | 1975-11-12 | Sposob poluchenija zamehhennykh 2-skobka-2-piridil-metil-sul'finil-skobka zakryta-benzimidazolov |
SU752189960A SU602118A3 (ru) | 1974-05-16 | 1975-11-13 | Способ получени производных бензимидазола или их солей |
FR7534910A FR2331340A1 (fr) | 1974-05-16 | 1975-11-14 | Nouveaux derives du benzimidazole, procede pour leur obtention et compositions pharmaceutiques les contenant |
DD189463A DD122534A5 (US06897227-20050524-C00065.png) | 1974-05-16 | 1975-11-14 | |
CA239,643A CA1055033A (en) | 1974-05-16 | 1975-11-14 | 2-(2-heterocyclic-methylsulphinyl)-benzimidazole compounds |
CH1481475A CH623814A5 (en) | 1974-05-16 | 1975-11-14 | Process for the preparation of novel benzimidazoles |
JP50137712A JPS5262275A (en) | 1974-05-16 | 1975-11-15 | Production of organic compound |
FR7616732A FR2392021A1 (fr) | 1974-05-16 | 1976-06-03 | Nouveaux derives du benzimidazole et procede pour leur obtention |
AT752276A AT351524B (de) | 1974-05-16 | 1976-10-11 | Verfahren zur herstellung von neuen benzimida- zolderivaten, ihren salzen und optischen isomeren |
DK783659A DK365978A (da) | 1974-05-16 | 1978-08-18 | Mellemprodukt til anvendelse ved fremstilling af benzimidazolderivater |
CS786886A CS196290B2 (en) | 1974-05-16 | 1978-10-23 | Process for preparing new compounds |
HU8782 | 1982-02-25 | ||
MY159/82A MY8200159A (en) | 1974-05-16 | 1982-12-30 | 2-[heterocylic substituted alkylsulphinyl]-benzimidazoles and their pharmaceutical compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
DE2548340A1 DE2548340A1 (de) | 1977-05-05 |
DE2548340C2 true DE2548340C2 (US06897227-20050524-C00065.png) | 1987-12-03 |
Family
ID=40486266
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19752548340 Granted DE2548340A1 (de) | 1974-05-16 | 1975-10-29 | Benzimidazole, verfahren zu deren herstellung und sie enthaltende mittel |
Country Status (22)
Families Citing this family (125)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN148930B (US06897227-20050524-C00065.png) * | 1977-09-19 | 1981-07-25 | Hoffmann La Roche | |
AT406119B (de) * | 1978-04-14 | 2000-02-25 | Haessle Ab | Verfahren zur herstellung von granulaten bzw. tabletten oder kapseln zur oralen verabreichung |
AT375365B (de) * | 1978-04-14 | 1984-07-25 | Haessle Ab | Verfahren zur herstellung von neuen 2-pyridylalkyl-sulfinyl-benzimidazolen, von deren hydraten, stereoisomeren und salzen |
SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
US4359465A (en) * | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
CH644116A5 (de) * | 1980-08-21 | 1984-07-13 | Hoffmann La Roche | Imidazolderivate. |
ZA825106B (en) * | 1981-08-13 | 1983-04-27 | Haessle Ab | Novel pharmaceutical compositions |
US4472409A (en) * | 1981-11-05 | 1984-09-18 | Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung | 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects |
KR840002371A (ko) * | 1981-11-05 | 1984-06-25 | 귄터 미카엘, 헤르페르트 수키 | 치환된 벤즈 이미다졸의 제조방법 |
DE3216843C2 (de) * | 1982-05-05 | 1986-10-23 | Ludwig Heumann & Co GmbH, 8500 Nürnberg | 3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
SE8300736D0 (sv) * | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
SE8301182D0 (sv) * | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
HU191756B (en) * | 1983-05-03 | 1987-04-28 | Byk Gulden Lomberg Chem Fab | Process for preparing new fluoro-alkoxy-benzimidazole derivatives |
IL71664A (en) * | 1983-05-03 | 1987-11-30 | Byk Gulden Lomberg Chem Fab | Fluoroalkoxy compounds,process for their preparation and pharmaceutical compositions containing the same |
US5077407A (en) * | 1983-07-01 | 1991-12-31 | The Upjohn Company | Substituted 2-[monoannelated (3,4-,4,5-, and 5,6-) pyridylalkylenesulfinyl]benzimidazoles |
CA1259070A (en) * | 1983-07-01 | 1989-09-05 | Upjohn Company (The) | Substituted 2-¬monoannelated(3,4-,4,5-, and 5,6-)- pyridylalkylenesulfinyl|-benzimidazoles |
DE3333314A1 (de) * | 1983-09-15 | 1985-03-28 | Hoechst Ag, 6230 Frankfurt | Substituierte pyrido(1,2-c)imidazo(1,2-a)benzimidazole, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen |
US4575554A (en) * | 1983-12-05 | 1986-03-11 | The Upjohn Company | Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents |
PH23995A (en) * | 1984-01-09 | 1990-02-09 | Janssen Pharmaceutica Nv | 4((bicycle heterocyclyl)-methyl and hetero)piperidines |
DE3585252D1 (de) * | 1984-07-06 | 1992-03-05 | Fisons Plc | Benzimidazole, und verfahren zu deren herstellung, deren formulierung und verwendung als magensaeuresekretionshemmende verbindungen. |
SE8404065D0 (sv) * | 1984-08-10 | 1984-08-10 | Haessle Ab | Novel biologically active compounds |
JPS6150978A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
JPS6150979A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
US4619997A (en) * | 1984-09-06 | 1986-10-28 | The Upjohn Company | Substituted 2-pyridylmethylthio and sulfinyl-benzimidazoles as gastric antisecretory agents |
KR890000387B1 (ko) * | 1984-09-24 | 1989-03-16 | 디 엎존 캄파니 | 2-(피리딜알켄술 피닐)벤즈 이미드아졸류의 n-치환 유도체의 제조방법 |
AU568441B2 (en) * | 1984-09-24 | 1987-12-24 | Upjohn Company, The | 2-(pyridylalkenesulfinyl) benzimidazole derivatives |
DE3579436D1 (de) * | 1984-12-18 | 1990-10-04 | Otsuka Pharma Co Ltd | Tetrahydrochinolin- derivate, verfahren zu deren herstellung und diese enthaltende antimagengeschwuerzusammensetzungen. |
GB8526154D0 (en) * | 1985-02-06 | 1985-11-27 | Kotobuki Seiyaku Co Ltd | 2-substituted cyclo-heptoimidazoles |
DK8600939A (US06897227-20050524-C00065.png) * | 1985-03-05 | 1986-09-06 | ||
FI861772A (fi) * | 1985-05-07 | 1986-11-08 | Chemie Linz Ag | Nya tieno(2,3-d)imidazolderivat och foerfarande for deras framstaellning. |
US5869513A (en) * | 1985-05-24 | 1999-02-09 | G. D. Searle & Co. | 2- (1H-benzimidazol-2-ylsulfinyl)methyl!benzenamines |
AU5768886A (en) | 1985-05-24 | 1986-11-27 | G.D. Searle & Co. | 2-((1-h-benzimidazol-2-ylsulfinyl)methyl)benzenamines |
US4738975A (en) * | 1985-07-02 | 1988-04-19 | Takeda Chemical Industries, Ltd. | Pyridine derivatives, and use as anti-ulcer agents |
DK337086A (da) * | 1985-08-12 | 1987-02-13 | Hoffmann La Roche | Benzimidazolderivater |
AR243167A1 (es) | 1985-08-24 | 1993-07-30 | Hoechst Ag | Procedimiento para la preparacion de toluidinas sustituidas. |
SE8505112D0 (sv) * | 1985-10-29 | 1985-10-29 | Haessle Ab | Novel pharmacological compounds |
US5433959A (en) * | 1986-02-13 | 1995-07-18 | Takeda Chemical Industries, Ltd. | Stabilized pharmaceutical composition |
US6749864B2 (en) * | 1986-02-13 | 2004-06-15 | Takeda Chemical Industries, Ltd. | Stabilized pharmaceutical composition |
SE8600658D0 (sv) * | 1986-02-14 | 1986-02-14 | Haessle Ab | Novel composition of matter |
DE3777855D1 (de) | 1986-02-20 | 1992-05-07 | Hoechst Ag | Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer. |
WO1987005296A1 (en) * | 1986-03-07 | 1987-09-11 | Pfizer Inc. | 2-[(2-pyridyl)methylsulfinyl]thienoimidazoles and related compounds as antiulcer agents |
EP0239129B1 (en) * | 1986-03-28 | 1991-09-25 | Otsuka Pharmaceutical Co., Ltd. | Hydroquinoline compounds, compositions containing same and processes for preparing same |
US4687775A (en) * | 1986-07-17 | 1987-08-18 | G. D. Searle & Co. | 2-[(Imidazo[1,2-a]pyridinylmethyl)sulfinyl]-1H-benzimidazoles |
US4772619A (en) * | 1986-07-17 | 1988-09-20 | G. D. Searle & Co. | [(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines |
US4721718A (en) * | 1986-08-18 | 1988-01-26 | G. D. Searle & Co. | 2-[(imidazo[1,2-a]pyridin-3-ylmethyl)sulfinyl]-1H-benzimidazoles useful in the treatment and prevention of ulcers |
SE8604998D0 (sv) | 1986-11-21 | 1986-11-21 | Haessle Ab | Novel pharmacological compounds |
NZ222495A (en) | 1986-11-21 | 1991-04-26 | Haessle Ab | Benzimidazole derivatives and pharmaceutical compositions |
DE3639926A1 (de) * | 1986-11-22 | 1988-06-01 | Hoechst Ag | Substituierte thienoimidazoltoluidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer |
GB8630080D0 (en) * | 1986-12-17 | 1987-01-28 | Glaxo Group Ltd | Medicaments |
US5330982A (en) * | 1986-12-17 | 1994-07-19 | Glaxo Group Limited | Pharmaceutical composition containing a 5-HT receptor antagonist and an H+ K+ Atpase inhibitor and a method of treating gastrointestingal disorders therewith |
DE3723327A1 (de) * | 1987-07-15 | 1989-02-02 | Hoechst Ag | Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer, magenschutzmittel sowie als medikament gegen intestinale entzuendungen |
HU886738D0 (en) * | 1987-10-30 | 1990-02-28 | Haessle Ab | Process for the preparation of pharmaceutical compositions against osteoporosis containing 2-pyridinyl-methyl-(sulfinyl or thio)-benzimidazoles |
KR920003928B1 (ko) * | 1988-09-20 | 1992-05-18 | 히사미쯔세이야꾸 가부시기가이샤 | 신규의 디벤즈[b,e]옥세핀유도체 |
EG19302A (en) * | 1988-12-22 | 1994-11-30 | Haessle Ab | Compound with gastric acid inhibitory effect and process for its preparation |
SE8804628D0 (sv) | 1988-12-22 | 1988-12-22 | Ab Haessle | New compounds |
SE8804629D0 (sv) | 1988-12-22 | 1988-12-22 | Ab Haessle | New therapeutically active compounds |
ATE110069T1 (de) * | 1989-11-29 | 1994-09-15 | Toa Eiyo Ltd | Cycloheptenopyridinderivate, verfahren zu ihrer herstellung und diese enthaltende antiulkusmitteln. |
US5049674A (en) | 1989-12-20 | 1991-09-17 | Aktiebolaget Hassle | Therapeutically active fluoro substituted benzimidazoles |
US4965269A (en) * | 1989-12-20 | 1990-10-23 | Ab Hassle | Therapeutically active chloro substituted benzimidazoles |
US5274099A (en) * | 1989-12-20 | 1993-12-28 | Aktiebolaget Hassle | Therapeutically active fluoro substituted benzimidazoles |
JP2524420B2 (ja) * | 1990-05-16 | 1996-08-14 | 明治製菓株式会社 | ピペリジン誘導体及びそれらを有効成分とする抗潰瘍剤 |
SE9002206D0 (sv) | 1990-06-20 | 1990-06-20 | Haessle Ab | New compounds |
US5364875A (en) * | 1992-05-11 | 1994-11-15 | The Du Pont Merck Pharmaceutical Company | Imidazoles linked to bicyclic heterocyclic groups for the treatment of atherosclerosis |
RU95105442A (ru) * | 1992-07-08 | 1997-02-20 | Монсанто Компани (US) | Способ лечения язвы желудка у свиней, изделие для лечения язвы желудка у свиней |
NZ254237A (en) * | 1992-07-28 | 1995-12-21 | Astra Ab | Injectable solution of a 2-[(2-pyridyl)methylsulphinyl]-benzimidazole or a salt thereof; an injection kit |
TW280770B (US06897227-20050524-C00065.png) | 1993-10-15 | 1996-07-11 | Takeda Pharm Industry Co Ltd | |
WO1995029897A1 (en) | 1994-04-29 | 1995-11-09 | G.D. Searle & Co. | METHOD OF USING (H+/K+) ATPase INHIBITORS AS ANTIVIRAL AGENTS |
EP0849259A4 (en) | 1995-07-17 | 1998-11-11 | Fuji Photo Film Co Ltd | BENZIMIDAZOLE COMPOUNDS |
US5824339A (en) * | 1995-09-08 | 1998-10-20 | Takeda Chemical Industries, Ltd | Effervescent composition and its production |
AU6998796A (en) * | 1995-09-21 | 1997-04-28 | Pharma Pass Llc | Novel composition containing an acid-labile benzimidazole and process for its preparation |
DE69814862T2 (de) * | 1997-07-11 | 2004-02-19 | Eisai Co., Ltd. | Verfahren zur herstellung von pyridinderivaten |
US6096340A (en) * | 1997-11-14 | 2000-08-01 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
US6174548B1 (en) | 1998-08-28 | 2001-01-16 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
GB9805558D0 (en) * | 1998-03-17 | 1998-05-13 | Knoll Ag | Chemical process` |
ES2274625T3 (es) | 1998-05-18 | 2007-05-16 | Takeda Pharmaceutical Company Limited | Comprimidos desintegrables en la boca que comprenden un bencimidazol. |
US6093734A (en) * | 1998-08-10 | 2000-07-25 | Partnership Of Michael E. Garst, George Sachs, And Jai Moo Shin | Prodrugs of proton pump inhibitors |
JP4346243B2 (ja) * | 1998-08-10 | 2009-10-21 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | プロトン・ポンプ・インヒビターのプロドラッグ |
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Publication number | Priority date | Publication date | Assignee | Title |
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GB1234058A (US06897227-20050524-C00065.png) * | 1968-10-21 | 1971-06-03 | ||
DE1903755B2 (de) * | 1969-01-25 | 1971-04-22 | Th Goldschmidt AG, 4300 Essen | Verfahren zur herstellung von zinnhaltigen keramischen farbkoerpern |
SE418966B (sv) * | 1974-02-18 | 1981-07-06 | Haessle Ab | Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan |
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1974
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1975
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- 1975-08-15 FI FI752327A patent/FI63756C/fi not_active IP Right Cessation
- 1975-08-18 DK DK372175AA patent/DK140840B/da not_active IP Right Cessation
- 1975-10-20 ZA ZA00756600A patent/ZA756600B/xx unknown
- 1975-10-20 GB GB43039/75A patent/GB1525958A/en not_active Expired
- 1975-10-20 CY CY1125A patent/CY1125A/xx unknown
- 1975-10-23 IE IE2313/75A patent/IE42451B1/en unknown
- 1975-10-29 DE DE19752548340 patent/DE2548340A1/de active Granted
- 1975-11-04 AT AT838075A patent/AT337697B/de not_active IP Right Cessation
- 1975-11-05 CS CS757458A patent/CS196289B2/cs unknown
- 1975-11-10 NL NL7513141A patent/NL7513141A/xx not_active Application Discontinuation
- 1975-11-11 US US05/630,916 patent/US4045563A/en not_active Expired - Lifetime
- 1975-11-12 HU HU75HE00000696A patent/HU172653B/hu unknown
- 1975-11-13 SU SU752189960A patent/SU602118A3/ru active
- 1975-11-14 FR FR7534910A patent/FR2331340A1/fr active Granted
- 1975-11-14 CA CA239,643A patent/CA1055033A/en not_active Expired
- 1975-11-14 CH CH1481475A patent/CH623814A5/de not_active IP Right Cessation
- 1975-11-14 DD DD189463A patent/DD122534A5/xx unknown
- 1975-11-15 JP JP50137712A patent/JPS5262275A/ja active Granted
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1976
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- 1976-10-11 AT AT752276A patent/AT351524B/de not_active IP Right Cessation
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1978
- 1978-08-18 DK DK783659A patent/DK365978A/da unknown
- 1978-10-23 CS CS786886A patent/CS196290B2/cs unknown
-
1979
- 1979-10-31 CH CH976079A patent/CH623582A5/de not_active IP Right Cessation
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1981
- 1981-06-04 FI FI811747A patent/FI65617C/fi not_active IP Right Cessation
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