DE2538075A1 - N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung - Google Patents

N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung

Info

Publication number
DE2538075A1
DE2538075A1 DE19752538075 DE2538075A DE2538075A1 DE 2538075 A1 DE2538075 A1 DE 2538075A1 DE 19752538075 DE19752538075 DE 19752538075 DE 2538075 A DE2538075 A DE 2538075A DE 2538075 A1 DE2538075 A1 DE 2538075A1
Authority
DE
Germany
Prior art keywords
tetrahydrofurfuryl
group
noroxymorphone
acid
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19752538075
Other languages
German (de)
English (en)
Inventor
Adolf Dr Langbein
Herbert Dr Merz
Klaus Dr Stockhaus
Gerhard Dr Walther
Helmut Dr Wick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
C.H. Boehringer Sohn AG and Co KG
Original Assignee
C.H. Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H. Boehringer Sohn AG and Co KG filed Critical C.H. Boehringer Sohn AG and Co KG
Priority to DE19752538075 priority Critical patent/DE2538075A1/de
Priority to AT605378A priority patent/AT358193B/de
Priority to AT553976A priority patent/AT350737B/de
Priority to AT605578A priority patent/AT358195B/de
Priority to AT605678A priority patent/AT358196B/de
Priority to AT605478A priority patent/AT358194B/de
Priority to PH18780A priority patent/PH13780A/en
Priority to US05/714,045 priority patent/US4100288A/en
Priority to RO7687297A priority patent/RO69457A/ro
Priority to ES450897A priority patent/ES450897A1/es
Priority to SU762389512A priority patent/SU612631A3/ru
Priority to FI762430A priority patent/FI762430A7/fi
Priority to BG034062A priority patent/BG27545A3/xx
Priority to IL50355A priority patent/IL50355A/xx
Priority to BG034743A priority patent/BG27546A4/xx
Priority to CH1079676A priority patent/CH622521A5/de
Priority to CS778646A priority patent/CS192599B2/cs
Priority to DD194461A priority patent/DD127145A5/xx
Priority to CS765528A priority patent/CS192564B2/cs
Priority to NO762932A priority patent/NO145793C/no
Priority to HU76BO1629A priority patent/HU176929B/hu
Priority to IE1911/76A priority patent/IE44069B1/en
Priority to GB35603/76A priority patent/GB1519719A/en
Priority to AU17201/76A priority patent/AU499926B2/en
Priority to PL1976213963A priority patent/PL110724B1/pl
Priority to JP51102168A priority patent/JPS5231100A/ja
Priority to NL7609485A priority patent/NL7609485A/xx
Priority to SE7609495A priority patent/SE7609495L/xx
Priority to NZ181864A priority patent/NZ181864A/xx
Priority to PL1976192020A priority patent/PL109091B1/pl
Priority to LU75667A priority patent/LU75667A1/xx
Priority to CA259,909A priority patent/CA1068266A/en
Priority to MX764858U priority patent/MX4133E/es
Priority to PT65521A priority patent/PT65521B/pt
Priority to GR51547A priority patent/GR61158B/el
Priority to ZA00765120A priority patent/ZA765120B/xx
Priority to BE170118A priority patent/BE845563A/xx
Priority to YU02081/76A priority patent/YU208176A/xx
Priority to DK386876A priority patent/DK143278C/da
Priority to FR7625985A priority patent/FR2321888A1/fr
Priority to ES454084A priority patent/ES454084A1/es
Priority to ES454087A priority patent/ES454087A2/es
Priority to ES454086A priority patent/ES454086A1/es
Priority to ES454085A priority patent/ES454085A1/es
Publication of DE2538075A1 publication Critical patent/DE2538075A1/de
Priority to SU772485952A priority patent/SU638262A3/ru
Priority to CH699680A priority patent/CH624117A5/de
Priority to CH699580A priority patent/CH624116A5/de
Priority to CH699480A priority patent/CH624115A5/de
Priority to CH699380A priority patent/CH624114A5/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE19752538075 1975-08-27 1975-08-27 N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung Withdrawn DE2538075A1 (de)

Priority Applications (49)

Application Number Priority Date Filing Date Title
DE19752538075 DE2538075A1 (de) 1975-08-27 1975-08-27 N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung
AT605378A AT358193B (de) 1975-08-27 1976-07-28 Verfahren zur herstellung neuer n-tetrahydro- furfuryl-noroxymorphone und deren saeure- additionssalzen
AT553976A AT350737B (de) 1975-08-27 1976-07-28 Verfahren zur herstellung neuer n-tetrahydro- furfuryl-noroxymorphone und deren saeure- additionssalzen
AT605578A AT358195B (de) 1975-08-27 1976-07-28 Verfahren zur herstellung neuer n-tetrahydro- furfuryl-noroxymorphone und deren saeure- additionssalzen
AT605678A AT358196B (de) 1975-08-27 1976-07-28 Verfahren zur herstellung neuer n-tetrahydro- furfuryl-noroxymorphone und deren saeure- additionssalzen
AT605478A AT358194B (de) 1975-08-27 1976-07-28 Verfahren zur herstellung neuer n-tetrahydro- furfuryl-noroxymorphone und deren saeure- additionssalzen
PH18780A PH13780A (en) 1975-08-27 1976-08-12 N-tetrahydrofurfuryl-noroxynorphones,their salts,and analgesic compositions and methods employing them
US05/714,045 US4100288A (en) 1975-08-27 1976-08-13 N-Tetrahydrofurfuryl-noroxymorphones, their salts, and analgesic compositions and methods employing them
RO7687297A RO69457A (ro) 1975-08-27 1976-08-13 Procedeu pentru prepararea n-(r-tetrahidrofurfuril)-noroximorfonei sia n-(s-tetrahidrofurfuril)-noroximorfonei
ES450897A ES450897A1 (es) 1975-08-27 1976-08-21 Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona.
SU762389512A SU612631A3 (ru) 1975-08-27 1976-08-23 Способ получени -(тетрагидрофурфурил)нороксиморфонов или их солей
FI762430A FI762430A7 (enExample) 1975-08-27 1976-08-24
BG034062A BG27545A3 (bg) 1975-08-27 1976-08-25 Метод за получаване на n-тетрахидрофурфорил-пороксиморфини и техни соли
IL50355A IL50355A (en) 1975-08-27 1976-08-25 N-tetrahydrofurfuryl noroxymorphone derivatives,their preparation and pharmaceutical compositions containing them
BG034743A BG27546A4 (bg) 1975-08-27 1976-08-25 Метод за получаване на n-тетрахидрофурил-порокси-морфини и техни соли
CH1079676A CH622521A5 (enExample) 1975-08-27 1976-08-25
CS778646A CS192599B2 (en) 1975-08-27 1976-08-25 Method of preparing novel diastereoisomers of n-tetrahydrofurfuryl-oxo-morphone
DD194461A DD127145A5 (enExample) 1975-08-27 1976-08-25
CS765528A CS192564B2 (en) 1975-08-27 1976-08-25 Method of producing new diastereomeres of n-tetrahydrofurfurylnoroxymorphone
NO762932A NO145793C (no) 1975-08-27 1976-08-26 Analogifremgangsmaate for fremstilling av den fysiologisk aktive forbindelse n-(r-tetrahydrofurfuryl)-noroksymorfon
HU76BO1629A HU176929B (hu) 1975-08-27 1976-08-26 Sposob poluchenija novykh n-tetragidro-furfuril-noroksimorfonov i kisloto-addicionnykh solejj
IE1911/76A IE44069B1 (en) 1975-08-27 1976-08-26 Noroxymorphones
GB35603/76A GB1519719A (en) 1975-08-27 1976-08-26 Noroxymorphones
AU17201/76A AU499926B2 (en) 1975-08-27 1976-08-26 Chemical compounds
PL1976213963A PL110724B1 (en) 1975-08-27 1976-08-26 Method of producing new diastereomers of n-tetrahydrofurfurylonoroxymorphones
JP51102168A JPS5231100A (en) 1975-08-27 1976-08-26 Nntetrahydrofurfuryll noroxymorphone * acid adduct salt thereof and parmaceutical composition containing same and production thereof
NL7609485A NL7609485A (nl) 1975-08-27 1976-08-26 Werkwijze voor de bereiding van nieuwe n-tetra- hydrofurfuryl-noroxymorfonen.
SE7609495A SE7609495L (sv) 1975-08-27 1976-08-26 N-tetrahydrofurfuryl-noroximorfon, dess syraadditionssalter, lekemedel innehallande dessa samt forfarande for framstellning derav
NZ181864A NZ181864A (en) 1975-08-27 1976-08-26 Noroxymorphones and pharmaceutical compositions
PL1976192020A PL109091B1 (en) 1975-08-27 1976-08-26 Method of producing new diastereomers of n-tetrahydrofurfuryle-noroxymorphones
LU75667A LU75667A1 (enExample) 1975-08-27 1976-08-26
CA259,909A CA1068266A (en) 1975-08-27 1976-08-26 N-tetrahydrofurfuryl-noroxymorphones, the acid addition salts thereof, pharmaceuticals comprising same as well as process for production thereof
MX764858U MX4133E (es) 1975-08-27 1976-08-26 Procedimiento para la preparacion de n-tetrahidrofurfuril-noroximorfonas diastereoisomeras
PT65521A PT65521B (de) 1975-08-27 1976-08-26 "n-te trahydrofurfuryl-noroxymorphone deren saureadditionssalze diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung
GR51547A GR61158B (en) 1975-08-27 1976-08-26 N-tetrahydrofurfuryl-noroxymorphone,salts thereof by addition of acid,pharmaceutical mediums containing them and process for the preparation thereof
ZA00765120A ZA765120B (en) 1975-08-27 1976-08-26 Improvements relating to n-tetrahydro-furfuryl-noroxymorphones
BE170118A BE845563A (fr) 1975-08-27 1976-08-26 N-tetrahydrofurfuryl-noroxymorphones, leurs sels d'addition avec des acides, procede pour leur preparation et medicaments en renfermant
YU02081/76A YU208176A (en) 1975-08-27 1976-08-26 Process for preparing n-tetrahydrofurfuryl-nor-oximorphones
DK386876A DK143278C (da) 1975-08-27 1976-08-26 Analogifremgangsmaade til fremstilling af n-(r-tetrahydrofurfuryl)-noroxymorphon eller syreadditionssalte deraf
FR7625985A FR2321888A1 (fr) 1975-08-27 1976-08-27 N-tetrahydrofurfuryl-noroxymorphones, leurs sels d'addition avec des acides, procedes pour leur preparation et medicaments en renfermant
ES454084A ES454084A1 (es) 1975-08-27 1976-12-09 Procedimiento para la preparmacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona nuevas.
ES454087A ES454087A2 (es) 1975-08-27 1976-12-09 Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona nuevas.
ES454086A ES454086A1 (es) 1975-08-27 1976-12-09 Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-norosimorfona nuevas.
ES454085A ES454085A1 (es) 1975-08-27 1976-12-09 Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona nuevas.
SU772485952A SU638262A3 (ru) 1975-08-27 1977-05-31 Способ получени диастереомерных -(тетрагидрофурфурил)-нороксиморфонов или их солей
CH699680A CH624117A5 (enExample) 1975-08-27 1980-09-18
CH699580A CH624116A5 (enExample) 1975-08-27 1980-09-18
CH699480A CH624115A5 (enExample) 1975-08-27 1980-09-18
CH699380A CH624114A5 (enExample) 1975-08-27 1980-09-18

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752538075 DE2538075A1 (de) 1975-08-27 1975-08-27 N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
DE2538075A1 true DE2538075A1 (de) 1977-03-17

Family

ID=5954931

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752538075 Withdrawn DE2538075A1 (de) 1975-08-27 1975-08-27 N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung

Country Status (33)

Country Link
US (1) US4100288A (enExample)
JP (1) JPS5231100A (enExample)
AT (1) AT350737B (enExample)
AU (1) AU499926B2 (enExample)
BE (1) BE845563A (enExample)
BG (2) BG27545A3 (enExample)
CA (1) CA1068266A (enExample)
CH (5) CH622521A5 (enExample)
CS (2) CS192599B2 (enExample)
DD (1) DD127145A5 (enExample)
DE (1) DE2538075A1 (enExample)
DK (1) DK143278C (enExample)
ES (5) ES450897A1 (enExample)
FI (1) FI762430A7 (enExample)
FR (1) FR2321888A1 (enExample)
GB (1) GB1519719A (enExample)
GR (1) GR61158B (enExample)
HU (1) HU176929B (enExample)
IE (1) IE44069B1 (enExample)
IL (1) IL50355A (enExample)
LU (1) LU75667A1 (enExample)
MX (1) MX4133E (enExample)
NL (1) NL7609485A (enExample)
NO (1) NO145793C (enExample)
NZ (1) NZ181864A (enExample)
PH (1) PH13780A (enExample)
PL (2) PL110724B1 (enExample)
PT (1) PT65521B (enExample)
RO (1) RO69457A (enExample)
SE (1) SE7609495L (enExample)
SU (2) SU612631A3 (enExample)
YU (1) YU208176A (enExample)
ZA (1) ZA765120B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0096279A1 (de) * 1982-06-03 1983-12-21 Boehringer Ingelheim Kg N-(2-Methoxyethyl)-noroxymorphon, dessen Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung
EP2590649A4 (en) * 2010-07-08 2014-01-29 Alkermes Pharma Ireland Ltd PROCESS FOR SYNTHESIS OF SUBSTITUTED MORPHINANES

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4272541A (en) * 1978-06-02 1981-06-09 Miles Laboratories, Inc. 7,8 and 7-8 Substituted 4,5α-epoxymorphinan-6-one compounds, and methods of treating pain and drug dependence with them
US4272540A (en) * 1979-04-24 1981-06-09 Sisa, Incorporated 14-Methoxymorphinan-6-one compounds and therapeutic methods of treating pain and drug dependence with them
ES2629766T3 (es) * 2006-04-21 2017-08-14 Nektar Therapeutics Reducción estereoselectiva de una morfinona
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
US9656961B2 (en) 2013-05-24 2017-05-23 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
ES2770978T3 (es) 2013-05-24 2020-07-06 Alkermes Pharma Ireland Ltd Análogos de morfanos y morfinanos y métodos de uso
CA3091826A1 (en) 2018-02-23 2019-08-29 Rhodes Technologies Novel opioid compounds and uses thereof
WO2022101444A1 (en) 2020-11-12 2022-05-19 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH446370A (de) 1964-03-05 1967-11-15 Hoffmann La Roche Verfahren zur Herstellung von Phenanthren-Derivaten
DE2238839A1 (de) * 1972-08-07 1974-02-14 Boehringer Sohn Ingelheim Neue morphinon-derivate, deren saeureadditionssalze, verfahren zu ihrer herstellung sowie ihre verwendung zur herstellung von arzneimitteln

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0096279A1 (de) * 1982-06-03 1983-12-21 Boehringer Ingelheim Kg N-(2-Methoxyethyl)-noroxymorphon, dessen Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung
EP2590649A4 (en) * 2010-07-08 2014-01-29 Alkermes Pharma Ireland Ltd PROCESS FOR SYNTHESIS OF SUBSTITUTED MORPHINANES

Also Published As

Publication number Publication date
IE44069L (en) 1977-02-27
CS192599B2 (en) 1979-08-31
BG27546A4 (bg) 1979-11-12
PT65521B (de) 1978-07-04
NO145793C (no) 1982-06-02
PL110724B1 (en) 1980-07-31
ES450897A1 (es) 1977-12-01
DK143278C (da) 1981-12-07
SE7609495L (sv) 1977-02-28
ATA553976A (de) 1978-11-15
MX4133E (es) 1982-01-06
PH13780A (en) 1980-09-26
ZA765120B (en) 1978-05-30
NZ181864A (en) 1978-06-20
LU75667A1 (enExample) 1977-09-13
DK143278B (da) 1981-08-03
GR61158B (en) 1978-09-30
AU1720176A (en) 1978-03-02
CH624115A5 (enExample) 1981-07-15
DK386876A (da) 1977-02-28
CH624116A5 (enExample) 1981-07-15
PT65521A (de) 1976-09-01
YU208176A (en) 1982-08-31
IL50355A0 (en) 1976-10-31
AU499926B2 (en) 1979-05-03
ES454086A1 (es) 1977-11-16
IL50355A (en) 1979-11-30
US4100288A (en) 1978-07-11
HU176929B (hu) 1981-06-28
NO762932L (enExample) 1977-03-01
CH624117A5 (enExample) 1981-07-15
PL109091B1 (en) 1980-05-31
CH622521A5 (enExample) 1981-04-15
CS192564B2 (en) 1979-08-31
FR2321888B1 (enExample) 1980-01-11
NO145793B (no) 1982-02-22
CA1068266A (en) 1979-12-18
SU638262A3 (ru) 1978-12-15
DD127145A5 (enExample) 1977-09-07
BE845563A (fr) 1977-02-28
JPS5231100A (en) 1977-03-09
ES454084A1 (es) 1977-11-16
ES454085A1 (es) 1977-11-16
PL192020A1 (pl) 1979-03-12
NL7609485A (nl) 1977-03-01
BG27545A3 (bg) 1979-11-12
AT350737B (de) 1979-06-11
CH624114A5 (enExample) 1981-07-15
SU612631A3 (ru) 1978-06-25
FR2321888A1 (fr) 1977-03-25
RO69457A (ro) 1981-04-30
FI762430A7 (enExample) 1977-02-28
GB1519719A (en) 1978-08-02
IE44069B1 (en) 1981-08-12
ES454087A2 (es) 1977-11-16

Similar Documents

Publication Publication Date Title
EP0006449B1 (de) 2-(2-Alkoxyethyl)-2'-hydroxy-6,7-benzomorphane, deren Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung
DE2437610A1 (de) Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung
DE2411382A1 (de) Neue 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung
DE3026201A1 (de) Aminoaetheroxide, verfahren zu ihrer herstellung sowie ihre therapeutische verwendung
DE2354002A1 (de) Neue n-(methoxymethyl-furylmethyl)6,7-benzomorphane und -morphinane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung
DE2112026C3 (de) 3-Phenyl-l-(2-[pyrrolidinyl-(l)]-äthylamino)-3,4dihydroisochinolin, seine Herstellung und die es enthaltenden medizinischen Zusammensetzungen
DE2108954A1 (en) 2-(furylmethyl)-6,7-benzomorphans - useful as cns active agents
DE60002733T2 (de) Diester prodrugs von decahydroischinoline-3-carbonsäure
EP0189370A2 (de) Spiro-dioxolane, -dithiolane und -oxothiolane
EP0096279B1 (de) N-(2-Methoxyethyl)-noroxymorphon, dessen Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung
CH624114A5 (enExample)
DE2242454A1 (de) 1-aethyl-imidazole, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
EP0056617B1 (de) Cycloheptenderivate, Verfahren und Zwischenprodukte für ihre Herstellung, sowie diese enthaltende Arzneimittel
DE2917456C2 (enExample)
DE1470002A1 (de) 5,6-Dihydromorphanthridinderivate
EP0004260B1 (de) Substituierte Chinolizidin- und Indolizidinmethanolderivate, Verfahren zur Herstellung derselben und Arzneimittel, welche diese enthalten
DE2222931C3 (de) Piperidinoalkylphenthiazine, Verfahren zur Herstellung derselben sowie diese enthaltende pharmazeutische Mittel
DE2217420B2 (de) N-Thienylmethyl-Heterocyclen, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE2807077C3 (de) Verfahren zur Herstellung von 6,73,9,10,11-Hexahydro-7,ll-methan-8,ll-dimethylbenzo [b] thieno 23-d azocin
DE2423897A1 (de) Neue n-(p-fluorbenzoylpropyl)-4- piperidylamide und verfahren zu ihrer herstellung
AT350571B (de) Verfahren zur herstellung von neuen 2- piperidinoalkyl-(1-benzofuranen, 1,4-benzo- dioxanen oder 1, 4-benzoxathianen)
DE1156079B (de) Verfahren zur Herstellung von 3-Alkylmercaptophenthiazinderivaten
DE2538252A1 (de) Neue 1 eckige klammer auf n-propargyl- piperidyl-(4) eckige klammer zu -imidazolidinone-(2) und verfahren zu ihrer herstellung
DE2262263A1 (de) Tetracyclische imidazole, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
DE3823576A1 (de) Substituierte 3-amino-3,4-dihydrocarbostyrile, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung

Legal Events

Date Code Title Description
8130 Withdrawal