PL192020A1 - Sposob wytwarzania n-tetrahydrofurfurylo-noroksymorfonow - Google Patents

Sposob wytwarzania n-tetrahydrofurfurylo-noroksymorfonow

Info

Publication number
PL192020A1
PL192020A1 PL19202076A PL19202076A PL192020A1 PL 192020 A1 PL192020 A1 PL 192020A1 PL 19202076 A PL19202076 A PL 19202076A PL 19202076 A PL19202076 A PL 19202076A PL 192020 A1 PL192020 A1 PL 192020A1
Authority
PL
Poland
Prior art keywords
noroxymorphone
tetrahydrofurfuryl
making
Prior art date
Application number
PL19202076A
Other languages
English (en)
Other versions
PL109091B1 (en
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of PL192020A1 publication Critical patent/PL192020A1/pl
Publication of PL109091B1 publication Critical patent/PL109091B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08Oxygen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL1976192020A 1975-08-27 1976-08-26 Method of producing new diastereomers of n-tetrahydrofurfuryle-noroxymorphones PL109091B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752538075 DE2538075A1 (de) 1975-08-27 1975-08-27 N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
PL192020A1 true PL192020A1 (pl) 1979-03-12
PL109091B1 PL109091B1 (en) 1980-05-31

Family

ID=5954931

Family Applications (2)

Application Number Title Priority Date Filing Date
PL1976192020A PL109091B1 (en) 1975-08-27 1976-08-26 Method of producing new diastereomers of n-tetrahydrofurfuryle-noroxymorphones
PL1976213963A PL110724B1 (en) 1975-08-27 1976-08-26 Method of producing new diastereomers of n-tetrahydrofurfurylonoroxymorphones

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL1976213963A PL110724B1 (en) 1975-08-27 1976-08-26 Method of producing new diastereomers of n-tetrahydrofurfurylonoroxymorphones

Country Status (33)

Country Link
US (1) US4100288A (pl)
JP (1) JPS5231100A (pl)
AT (1) AT350737B (pl)
AU (1) AU499926B2 (pl)
BE (1) BE845563A (pl)
BG (2) BG27546A4 (pl)
CA (1) CA1068266A (pl)
CH (5) CH622521A5 (pl)
CS (2) CS192564B2 (pl)
DD (1) DD127145A5 (pl)
DE (1) DE2538075A1 (pl)
DK (1) DK143278C (pl)
ES (5) ES450897A1 (pl)
FI (1) FI762430A (pl)
FR (1) FR2321888A1 (pl)
GB (1) GB1519719A (pl)
GR (1) GR61158B (pl)
HU (1) HU176929B (pl)
IE (1) IE44069B1 (pl)
IL (1) IL50355A (pl)
LU (1) LU75667A1 (pl)
MX (1) MX4133E (pl)
NL (1) NL7609485A (pl)
NO (1) NO145793C (pl)
NZ (1) NZ181864A (pl)
PH (1) PH13780A (pl)
PL (2) PL109091B1 (pl)
PT (1) PT65521B (pl)
RO (1) RO69457A (pl)
SE (1) SE7609495L (pl)
SU (2) SU612631A3 (pl)
YU (1) YU208176A (pl)
ZA (1) ZA765120B (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4272541A (en) * 1978-06-02 1981-06-09 Miles Laboratories, Inc. 7,8 and 7-8 Substituted 4,5α-epoxymorphinan-6-one compounds, and methods of treating pain and drug dependence with them
US4272540A (en) * 1979-04-24 1981-06-09 Sisa, Incorporated 14-Methoxymorphinan-6-one compounds and therapeutic methods of treating pain and drug dependence with them
DE3220831A1 (de) * 1982-06-03 1983-12-08 Boehringer Ingelheim KG, 6507 Ingelheim N-(2-methoxyethyl)-noroxymorphon, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
JP5586223B2 (ja) * 2006-04-21 2014-09-10 ネクター セラピューティクス モルヒノンの立体選択的還元
ES2708726T3 (es) * 2010-07-08 2019-04-10 Alkermes Pharma Ireland Ltd Proceso para la síntesis de morfinanos sustituidos
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
EP3003311A2 (en) 2013-05-24 2016-04-13 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
AU2014268361B2 (en) 2013-05-24 2018-09-06 Alkermes Pharma Ireland Limited Morphan and morphinan analogues, and methods of use
EP3755704A1 (en) * 2018-02-23 2020-12-30 Rhodes Technologies Inc. Novel opioid compounds and uses thereof
EP4243768A1 (en) 2020-11-12 2023-09-20 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH446370A (de) 1964-03-05 1967-11-15 Hoffmann La Roche Verfahren zur Herstellung von Phenanthren-Derivaten
DE2238839A1 (de) * 1972-08-07 1974-02-14 Boehringer Sohn Ingelheim Neue morphinon-derivate, deren saeureadditionssalze, verfahren zu ihrer herstellung sowie ihre verwendung zur herstellung von arzneimitteln

Also Published As

Publication number Publication date
NO145793B (no) 1982-02-22
BG27545A3 (en) 1979-11-12
PT65521A (de) 1976-09-01
CH624115A5 (pl) 1981-07-15
DK143278C (da) 1981-12-07
PT65521B (de) 1978-07-04
NZ181864A (en) 1978-06-20
ES454084A1 (es) 1977-11-16
US4100288A (en) 1978-07-11
BE845563A (fr) 1977-02-28
CH624114A5 (pl) 1981-07-15
ZA765120B (en) 1978-05-30
RO69457A (ro) 1981-04-30
LU75667A1 (pl) 1977-09-13
CH624116A5 (pl) 1981-07-15
DD127145A5 (pl) 1977-09-07
SU638262A3 (ru) 1978-12-15
CA1068266A (en) 1979-12-18
MX4133E (es) 1982-01-06
IL50355A0 (en) 1976-10-31
NO145793C (no) 1982-06-02
CH624117A5 (pl) 1981-07-15
ATA553976A (de) 1978-11-15
AT350737B (de) 1979-06-11
AU1720176A (en) 1978-03-02
FR2321888B1 (pl) 1980-01-11
GB1519719A (en) 1978-08-02
CS192564B2 (en) 1979-08-31
PL110724B1 (en) 1980-07-31
ES454086A1 (es) 1977-11-16
ES450897A1 (es) 1977-12-01
DE2538075A1 (de) 1977-03-17
IL50355A (en) 1979-11-30
DK386876A (da) 1977-02-28
GR61158B (en) 1978-09-30
AU499926B2 (en) 1979-05-03
YU208176A (en) 1982-08-31
NO762932L (pl) 1977-03-01
SU612631A3 (ru) 1978-06-25
NL7609485A (nl) 1977-03-01
CH622521A5 (pl) 1981-04-15
ES454085A1 (es) 1977-11-16
JPS5231100A (en) 1977-03-09
HU176929B (hu) 1981-06-28
FR2321888A1 (fr) 1977-03-25
PH13780A (en) 1980-09-26
IE44069L (en) 1977-02-27
BG27546A4 (en) 1979-11-12
CS192599B2 (en) 1979-08-31
IE44069B1 (en) 1981-08-12
PL109091B1 (en) 1980-05-31
ES454087A2 (es) 1977-11-16
SE7609495L (sv) 1977-02-28
DK143278B (da) 1981-08-03
FI762430A (pl) 1977-02-28

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