SE7609495L - N-tetrahydrofurfuryl-noroximorfon, dess syraadditionssalter, lekemedel innehallande dessa samt forfarande for framstellning derav - Google Patents

N-tetrahydrofurfuryl-noroximorfon, dess syraadditionssalter, lekemedel innehallande dessa samt forfarande for framstellning derav

Info

Publication number
SE7609495L
SE7609495L SE7609495A SE7609495A SE7609495L SE 7609495 L SE7609495 L SE 7609495L SE 7609495 A SE7609495 A SE 7609495A SE 7609495 A SE7609495 A SE 7609495A SE 7609495 L SE7609495 L SE 7609495L
Authority
SE
Sweden
Prior art keywords
noroximorphone
tetrahydrofurfuryl
procedures
preparation
products containing
Prior art date
Application number
SE7609495A
Other languages
English (en)
Inventor
H Merz
G Walther
A Langbein
K Stockhaus
H Wick
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of SE7609495L publication Critical patent/SE7609495L/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE7609495A 1975-08-27 1976-08-26 N-tetrahydrofurfuryl-noroximorfon, dess syraadditionssalter, lekemedel innehallande dessa samt forfarande for framstellning derav SE7609495L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752538075 DE2538075A1 (de) 1975-08-27 1975-08-27 N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
SE7609495L true SE7609495L (sv) 1977-02-28

Family

ID=5954931

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7609495A SE7609495L (sv) 1975-08-27 1976-08-26 N-tetrahydrofurfuryl-noroximorfon, dess syraadditionssalter, lekemedel innehallande dessa samt forfarande for framstellning derav

Country Status (33)

Country Link
US (1) US4100288A (sv)
JP (1) JPS5231100A (sv)
AT (1) AT350737B (sv)
AU (1) AU499926B2 (sv)
BE (1) BE845563A (sv)
BG (2) BG27546A4 (sv)
CA (1) CA1068266A (sv)
CH (5) CH622521A5 (sv)
CS (2) CS192564B2 (sv)
DD (1) DD127145A5 (sv)
DE (1) DE2538075A1 (sv)
DK (1) DK143278C (sv)
ES (5) ES450897A1 (sv)
FI (1) FI762430A (sv)
FR (1) FR2321888A1 (sv)
GB (1) GB1519719A (sv)
GR (1) GR61158B (sv)
HU (1) HU176929B (sv)
IE (1) IE44069B1 (sv)
IL (1) IL50355A (sv)
LU (1) LU75667A1 (sv)
MX (1) MX4133E (sv)
NL (1) NL7609485A (sv)
NO (1) NO145793C (sv)
NZ (1) NZ181864A (sv)
PH (1) PH13780A (sv)
PL (2) PL109091B1 (sv)
PT (1) PT65521B (sv)
RO (1) RO69457A (sv)
SE (1) SE7609495L (sv)
SU (2) SU612631A3 (sv)
YU (1) YU208176A (sv)
ZA (1) ZA765120B (sv)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4272541A (en) * 1978-06-02 1981-06-09 Miles Laboratories, Inc. 7,8 and 7-8 Substituted 4,5α-epoxymorphinan-6-one compounds, and methods of treating pain and drug dependence with them
US4272540A (en) * 1979-04-24 1981-06-09 Sisa, Incorporated 14-Methoxymorphinan-6-one compounds and therapeutic methods of treating pain and drug dependence with them
DE3220831A1 (de) * 1982-06-03 1983-12-08 Boehringer Ingelheim KG, 6507 Ingelheim N-(2-methoxyethyl)-noroxymorphon, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
JP5586223B2 (ja) * 2006-04-21 2014-09-10 ネクター セラピューティクス モルヒノンの立体選択的還元
ES2708726T3 (es) * 2010-07-08 2019-04-10 Alkermes Pharma Ireland Ltd Proceso para la síntesis de morfinanos sustituidos
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
EP3003311A2 (en) 2013-05-24 2016-04-13 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
AU2014268361B2 (en) 2013-05-24 2018-09-06 Alkermes Pharma Ireland Limited Morphan and morphinan analogues, and methods of use
EP3755704A1 (en) * 2018-02-23 2020-12-30 Rhodes Technologies Inc. Novel opioid compounds and uses thereof
EP4243768A1 (en) 2020-11-12 2023-09-20 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH446370A (de) 1964-03-05 1967-11-15 Hoffmann La Roche Verfahren zur Herstellung von Phenanthren-Derivaten
DE2238839A1 (de) * 1972-08-07 1974-02-14 Boehringer Sohn Ingelheim Neue morphinon-derivate, deren saeureadditionssalze, verfahren zu ihrer herstellung sowie ihre verwendung zur herstellung von arzneimitteln

Also Published As

Publication number Publication date
NO145793B (no) 1982-02-22
BG27545A3 (en) 1979-11-12
PT65521A (de) 1976-09-01
CH624115A5 (sv) 1981-07-15
DK143278C (da) 1981-12-07
PT65521B (de) 1978-07-04
NZ181864A (en) 1978-06-20
ES454084A1 (es) 1977-11-16
US4100288A (en) 1978-07-11
BE845563A (fr) 1977-02-28
CH624114A5 (sv) 1981-07-15
ZA765120B (en) 1978-05-30
RO69457A (ro) 1981-04-30
LU75667A1 (sv) 1977-09-13
CH624116A5 (sv) 1981-07-15
DD127145A5 (sv) 1977-09-07
SU638262A3 (ru) 1978-12-15
CA1068266A (en) 1979-12-18
MX4133E (es) 1982-01-06
IL50355A0 (en) 1976-10-31
NO145793C (no) 1982-06-02
CH624117A5 (sv) 1981-07-15
ATA553976A (de) 1978-11-15
AT350737B (de) 1979-06-11
AU1720176A (en) 1978-03-02
FR2321888B1 (sv) 1980-01-11
GB1519719A (en) 1978-08-02
CS192564B2 (en) 1979-08-31
PL110724B1 (en) 1980-07-31
ES454086A1 (es) 1977-11-16
ES450897A1 (es) 1977-12-01
DE2538075A1 (de) 1977-03-17
IL50355A (en) 1979-11-30
DK386876A (da) 1977-02-28
GR61158B (en) 1978-09-30
AU499926B2 (en) 1979-05-03
YU208176A (en) 1982-08-31
NO762932L (sv) 1977-03-01
SU612631A3 (ru) 1978-06-25
NL7609485A (nl) 1977-03-01
CH622521A5 (sv) 1981-04-15
ES454085A1 (es) 1977-11-16
JPS5231100A (en) 1977-03-09
HU176929B (hu) 1981-06-28
FR2321888A1 (fr) 1977-03-25
PH13780A (en) 1980-09-26
IE44069L (en) 1977-02-27
BG27546A4 (en) 1979-11-12
CS192599B2 (en) 1979-08-31
IE44069B1 (en) 1981-08-12
PL192020A1 (pl) 1979-03-12
PL109091B1 (en) 1980-05-31
ES454087A2 (es) 1977-11-16
DK143278B (da) 1981-08-03
FI762430A (sv) 1977-02-28

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