SE8402549L - Substituerade moranolinderivat - Google Patents
Substituerade moranolinderivatInfo
- Publication number
- SE8402549L SE8402549L SE8402549A SE8402549A SE8402549L SE 8402549 L SE8402549 L SE 8402549L SE 8402549 A SE8402549 A SE 8402549A SE 8402549 A SE8402549 A SE 8402549A SE 8402549 L SE8402549 L SE 8402549L
- Authority
- SE
- Sweden
- Prior art keywords
- same
- substituted
- moranoline derivatives
- derivatives
- substituted moranoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP53053603A JPS5943947B2 (ja) | 1978-05-03 | 1978-05-03 | N−置換モラノリン誘導体 |
JP8260678A JPS5943948B2 (ja) | 1978-07-06 | 1978-07-06 | 置換モラノリン誘導体 |
JP12066178A JPS5943949B2 (ja) | 1978-09-29 | 1978-09-29 | モラノリンのn−置換誘導体 |
JP571479A JPS6026387B2 (ja) | 1979-01-20 | 1979-01-20 | シンナミルモラノリン誘導体 |
Publications (3)
Publication Number | Publication Date |
---|---|
SE8402549L true SE8402549L (sv) | 1984-05-11 |
SE8402549D0 SE8402549D0 (sv) | 1984-05-11 |
SE451015B SE451015B (sv) | 1987-08-24 |
Family
ID=27454348
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7903817A SE436874B (sv) | 1978-05-03 | 1979-05-02 | N-substituerade moranolinderivat |
SE8402549A SE451015B (sv) | 1978-05-03 | 1984-05-11 | Substituerade moranolinderivat |
SE8402550A SE451016B (sv) | 1978-05-03 | 1984-05-11 | N-substituerade derivat av moranolin |
SE8402551A SE451017B (sv) | 1978-05-03 | 1984-05-11 | Cinnamylmoranolin-derivat |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7903817A SE436874B (sv) | 1978-05-03 | 1979-05-02 | N-substituerade moranolinderivat |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8402550A SE451016B (sv) | 1978-05-03 | 1984-05-11 | N-substituerade derivat av moranolin |
SE8402551A SE451017B (sv) | 1978-05-03 | 1984-05-11 | Cinnamylmoranolin-derivat |
Country Status (9)
Country | Link |
---|---|
US (1) | US4533668A (sv) |
CH (1) | CH642629A5 (sv) |
DE (1) | DE2915037C3 (sv) |
DK (1) | DK151623C (sv) |
FR (1) | FR2424910A1 (sv) |
GB (1) | GB2020278B (sv) |
IT (1) | IT1116820B (sv) |
NL (1) | NL175820C (sv) |
SE (4) | SE436874B (sv) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO154918C (no) * | 1977-08-27 | 1987-01-14 | Bayer Ag | Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin. |
DE2925943A1 (de) * | 1979-06-27 | 1981-01-29 | Bayer Ag | 1-alkadien-2,4-yl-2-hydroxymethyl3,4,5-trihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
DE2942365A1 (de) * | 1979-10-19 | 1981-05-14 | Bayer Ag, 5090 Leverkusen | 2-hydroxyalkyl-3,4,5-trihydroxy-(pi)-peridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
DE3007078A1 (de) * | 1980-02-26 | 1981-09-10 | Bayer Ag, 5090 Leverkusen | Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel sowie in der tierernaehrung |
JP2504000B2 (ja) * | 1986-09-02 | 1996-06-05 | 日本新薬株式会社 | グルコシルモラノリン誘導体 |
JPS6461459A (en) * | 1987-08-28 | 1989-03-08 | Nippon Shinyaku Co Ltd | Moranoline derivative |
US5192772A (en) * | 1987-12-09 | 1993-03-09 | Nippon Shinyaku Co. Ltd. | Therapeutic agents |
GB8827701D0 (en) * | 1987-12-09 | 1988-12-29 | Nippon Shinyaku Co Ltd | Thrombolytic &c compositions |
US4985445A (en) * | 1988-02-12 | 1991-01-15 | Meiji Seika Kaisha, Ltd. | Cancer cell metastasis inhibitors and novel compounds |
EP0350012A3 (en) * | 1988-07-08 | 1990-09-05 | Meiji Seika Kaisha Ltd. | Antiviral composition |
US5206251A (en) * | 1992-04-01 | 1993-04-27 | G. D. Searle & Co. | 2- and 3- amino and azido derivatives of 1,5-iminosugars |
US5342951A (en) * | 1992-04-01 | 1994-08-30 | G.D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
ATE142201T1 (de) * | 1992-04-01 | 1996-09-15 | Searle & Co | 2- und 3-amino und azidoderivate von 1,5- iminozuckern als antivirale arzneimittel |
US5268482A (en) * | 1992-04-01 | 1993-12-07 | G. D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
US5331096A (en) * | 1992-04-01 | 1994-07-19 | G. D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
US5216168A (en) * | 1992-04-01 | 1993-06-01 | G. D. Searle & Co. | 2- and 3- amino and azido derivatives of 1,5-iminosugars |
US5258518A (en) * | 1992-04-01 | 1993-11-02 | G. D. Searle & Co. | 2-substituted tertiary carbinol derivatives of deoxynojirimycin |
US6291657B1 (en) | 1993-05-13 | 2001-09-18 | Monsanto Company | Deoxygalactonojirimycin derivatives |
US5399567A (en) * | 1993-05-13 | 1995-03-21 | Monsanto Company | Method of treating cholera |
US5798366A (en) * | 1993-05-13 | 1998-08-25 | Monsanto Company | Method for treatment of CNS-involved lysosomal storage diseases |
US20030100532A1 (en) * | 1997-02-14 | 2003-05-29 | Gary S. Jacob | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections |
JP2001522833A (ja) * | 1997-11-10 | 2001-11-20 | ジー・ディー・サール・アンド・カンパニー | 多剤耐性を治療するためのアルキル化イミノ糖類の使用 |
US6689759B1 (en) | 1998-02-12 | 2004-02-10 | G. D. Searle & Co. | Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy |
BR9907882A (pt) | 1998-02-12 | 2000-10-17 | Searle & Co | Uso de compostos de 1,5-didesóxi-1,5-imino-d-glucitol n-substituìdos para o tratamento de infecções de vìrus de hepatite |
US6545021B1 (en) * | 1999-02-12 | 2003-04-08 | G.D. Searle & Co. | Use of substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds for treating hepatitis virus infections |
WO2001008672A2 (en) | 1999-02-12 | 2001-02-08 | G.D. Searle & Co. | Glucamine compounds for treating hepatitis virus infections |
WO2001060366A1 (en) * | 2000-02-14 | 2001-08-23 | Pharmacia Corporation | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds for treating hepatitis virus infections |
JP2008519840A (ja) | 2004-11-10 | 2008-06-12 | ジェンザイム・コーポレイション | 糖尿病の処置方法 |
AT502145B1 (de) * | 2005-03-24 | 2012-01-15 | Univ Graz Tech | Glycosidase-hemmendes iminoalditol |
ES2546181T3 (es) * | 2006-05-09 | 2015-09-21 | Genzyme Corporation | Métodos de tratar la enfermedad del hígado graso mediante inhibición de la síntesis de glucoesfingolípidos |
CN104876855A (zh) * | 2006-05-24 | 2015-09-02 | 联合治疗公司 | 脱氧吉瑞霉素和d-阿拉伯胶素醇类似物及使用方法 |
US8097728B2 (en) * | 2007-04-30 | 2012-01-17 | Philadelphia Health & Education Corporation | Iminosugar compounds with antiflavirus activity |
WO2008150486A2 (en) * | 2007-05-31 | 2008-12-11 | Genzyme Corporation | 2-acylaminopropoanol-type glucosylceramide synthase inhibitors |
JP5896601B2 (ja) | 2007-10-05 | 2016-03-30 | ジェンザイム コーポレーション | セラミド誘導体を用いる多発性嚢胞腎疾患の治療方法 |
EP2320886B1 (en) | 2008-07-28 | 2017-06-28 | Genzyme Corporation | Glucosylceramide synthase inhibition for the treatment of collapsing glomerulopathy and other glomerular disease |
KR101687039B1 (ko) | 2008-10-03 | 2016-12-15 | 젠자임 코포레이션 | 2-아실아미노프로판올형 글루코실세라미드 합성효소 억제제 |
US10328061B2 (en) | 2016-05-02 | 2019-06-25 | Florida State University Research Foundation, Inc. | Treatment of Zika virus infections using alpha-glucosidase inhibitors |
EP4106752A4 (en) | 2020-02-21 | 2024-03-20 | Florida State University Research Foundation, Inc. | TREATMENT OF HUMAN CORONAVIRUS INFECTIONS USING ALPHA-GLUCOSIDASE-GLYCOPROTEIN PROCESSING INHIBITORS |
WO2021224865A1 (en) * | 2020-05-07 | 2021-11-11 | Alectos Therapeutics Inc. | Non-lysosomal glucosylceramidase inhibitors and uses thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5282710A (en) * | 1975-12-29 | 1977-07-11 | Nippon Shinyaku Co Ltd | Extraction of effective drug component from mulberry |
DE2735316C3 (de) * | 1977-08-05 | 1981-01-29 | Basf Ag, 6700 Ludwigshafen | Verfahren zur Herstellung von nadeiförmigen, ferrimagnetischen Eisenoxiden |
-
1979
- 1979-03-21 GB GB7909865A patent/GB2020278B/en not_active Expired
- 1979-04-12 DE DE2915037A patent/DE2915037C3/de not_active Expired
- 1979-04-25 FR FR7910559A patent/FR2424910A1/fr active Granted
- 1979-04-27 US US06/033,839 patent/US4533668A/en not_active Expired - Lifetime
- 1979-05-01 DK DK178379A patent/DK151623C/da not_active IP Right Cessation
- 1979-05-02 SE SE7903817A patent/SE436874B/sv not_active IP Right Cessation
- 1979-05-02 IT IT48904/79A patent/IT1116820B/it active
- 1979-05-02 NL NLAANVRAGE7903421,A patent/NL175820C/xx not_active IP Right Cessation
- 1979-05-03 CH CH415879A patent/CH642629A5/de not_active IP Right Cessation
-
1984
- 1984-05-11 SE SE8402549A patent/SE451015B/sv not_active IP Right Cessation
- 1984-05-11 SE SE8402550A patent/SE451016B/sv not_active IP Right Cessation
- 1984-05-11 SE SE8402551A patent/SE451017B/sv not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SE451016B (sv) | 1987-08-24 |
SE8402551D0 (sv) | 1984-05-11 |
SE8402550L (sv) | 1984-05-11 |
GB2020278A (en) | 1979-11-14 |
SE7903817L (sv) | 1979-11-04 |
SE451015B (sv) | 1987-08-24 |
NL7903421A (nl) | 1979-11-06 |
DK151623B (da) | 1987-12-21 |
CH642629A5 (de) | 1984-04-30 |
SE8402550D0 (sv) | 1984-05-11 |
SE436874B (sv) | 1985-01-28 |
IT7948904A0 (it) | 1979-05-02 |
SE451017B (sv) | 1987-08-24 |
DK151623C (da) | 1988-07-18 |
FR2424910B1 (sv) | 1981-12-11 |
NL175820B (nl) | 1984-08-01 |
FR2424910A1 (fr) | 1979-11-30 |
DE2915037A1 (de) | 1979-11-08 |
US4533668A (en) | 1985-08-06 |
SE8402551L (sv) | 1984-05-11 |
NL175820C (nl) | 1985-01-02 |
SE8402549D0 (sv) | 1984-05-11 |
DE2915037B2 (de) | 1981-01-29 |
DE2915037C3 (de) | 1981-11-05 |
IT1116820B (it) | 1986-02-10 |
GB2020278B (en) | 1983-02-23 |
DK178379A (da) | 1979-11-04 |
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