SE8402549D0 - Substituerade moranolinderivat - Google Patents
Substituerade moranolinderivatInfo
- Publication number
- SE8402549D0 SE8402549D0 SE8402549A SE8402549A SE8402549D0 SE 8402549 D0 SE8402549 D0 SE 8402549D0 SE 8402549 A SE8402549 A SE 8402549A SE 8402549 A SE8402549 A SE 8402549A SE 8402549 D0 SE8402549 D0 SE 8402549D0
- Authority
- SE
- Sweden
- Prior art keywords
- same
- substituted
- moranoline derivatives
- derivatives
- substituted moranoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP53053603A JPS5943947B2 (ja) | 1978-05-03 | 1978-05-03 | N−置換モラノリン誘導体 |
JP8260678A JPS5943948B2 (ja) | 1978-07-06 | 1978-07-06 | 置換モラノリン誘導体 |
JP12066178A JPS5943949B2 (ja) | 1978-09-29 | 1978-09-29 | モラノリンのn−置換誘導体 |
JP571479A JPS6026387B2 (ja) | 1979-01-20 | 1979-01-20 | シンナミルモラノリン誘導体 |
Publications (3)
Publication Number | Publication Date |
---|---|
SE8402549D0 true SE8402549D0 (sv) | 1984-05-11 |
SE8402549L SE8402549L (sv) | 1984-05-11 |
SE451015B SE451015B (sv) | 1987-08-24 |
Family
ID=27454348
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7903817A SE436874B (sv) | 1978-05-03 | 1979-05-02 | N-substituerade moranolinderivat |
SE8402550A SE451016B (sv) | 1978-05-03 | 1984-05-11 | N-substituerade derivat av moranolin |
SE8402551A SE451017B (sv) | 1978-05-03 | 1984-05-11 | Cinnamylmoranolin-derivat |
SE8402549A SE451015B (sv) | 1978-05-03 | 1984-05-11 | Substituerade moranolinderivat |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7903817A SE436874B (sv) | 1978-05-03 | 1979-05-02 | N-substituerade moranolinderivat |
SE8402550A SE451016B (sv) | 1978-05-03 | 1984-05-11 | N-substituerade derivat av moranolin |
SE8402551A SE451017B (sv) | 1978-05-03 | 1984-05-11 | Cinnamylmoranolin-derivat |
Country Status (9)
Country | Link |
---|---|
US (1) | US4533668A (sv) |
CH (1) | CH642629A5 (sv) |
DE (1) | DE2915037C3 (sv) |
DK (1) | DK151623C (sv) |
FR (1) | FR2424910A1 (sv) |
GB (1) | GB2020278B (sv) |
IT (1) | IT1116820B (sv) |
NL (1) | NL175820C (sv) |
SE (4) | SE436874B (sv) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO154918C (no) * | 1977-08-27 | 1987-01-14 | Bayer Ag | Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin. |
DE2925943A1 (de) * | 1979-06-27 | 1981-01-29 | Bayer Ag | 1-alkadien-2,4-yl-2-hydroxymethyl3,4,5-trihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
DE2942365A1 (de) * | 1979-10-19 | 1981-05-14 | Bayer Ag, 5090 Leverkusen | 2-hydroxyalkyl-3,4,5-trihydroxy-(pi)-peridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
DE3007078A1 (de) * | 1980-02-26 | 1981-09-10 | Bayer Ag, 5090 Leverkusen | Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel sowie in der tierernaehrung |
JP2504000B2 (ja) * | 1986-09-02 | 1996-06-05 | 日本新薬株式会社 | グルコシルモラノリン誘導体 |
JPS6461459A (en) * | 1987-08-28 | 1989-03-08 | Nippon Shinyaku Co Ltd | Moranoline derivative |
GB8827701D0 (en) * | 1987-12-09 | 1988-12-29 | Nippon Shinyaku Co Ltd | Thrombolytic &c compositions |
US5192772A (en) * | 1987-12-09 | 1993-03-09 | Nippon Shinyaku Co. Ltd. | Therapeutic agents |
US4985445A (en) * | 1988-02-12 | 1991-01-15 | Meiji Seika Kaisha, Ltd. | Cancer cell metastasis inhibitors and novel compounds |
EP0350012A3 (en) * | 1988-07-08 | 1990-09-05 | Meiji Seika Kaisha Ltd. | Antiviral composition |
US5342951A (en) * | 1992-04-01 | 1994-08-30 | G.D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
US5331096A (en) * | 1992-04-01 | 1994-07-19 | G. D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
US5258518A (en) * | 1992-04-01 | 1993-11-02 | G. D. Searle & Co. | 2-substituted tertiary carbinol derivatives of deoxynojirimycin |
US5216168A (en) * | 1992-04-01 | 1993-06-01 | G. D. Searle & Co. | 2- and 3- amino and azido derivatives of 1,5-iminosugars |
ATE142201T1 (de) * | 1992-04-01 | 1996-09-15 | Searle & Co | 2- und 3-amino und azidoderivate von 1,5- iminozuckern als antivirale arzneimittel |
US5206251A (en) * | 1992-04-01 | 1993-04-27 | G. D. Searle & Co. | 2- and 3- amino and azido derivatives of 1,5-iminosugars |
US5268482A (en) * | 1992-04-01 | 1993-12-07 | G. D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
US5798366A (en) * | 1993-05-13 | 1998-08-25 | Monsanto Company | Method for treatment of CNS-involved lysosomal storage diseases |
US5399567A (en) * | 1993-05-13 | 1995-03-21 | Monsanto Company | Method of treating cholera |
US6291657B1 (en) * | 1993-05-13 | 2001-09-18 | Monsanto Company | Deoxygalactonojirimycin derivatives |
US20030100532A1 (en) * | 1997-02-14 | 2003-05-29 | Gary S. Jacob | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections |
EP1030839B1 (en) | 1997-11-10 | 2004-02-04 | G.D. SEARLE & CO. | Use of alkylated iminosugars to treat multidrug resistance |
KR20010040937A (ko) | 1998-02-12 | 2001-05-15 | 윌리암스 로저 에이 | 간염 바이러스 감염의 치료를 위한 n-치환된1,5-디데옥시-1,5-이미노-d-글루시톨 화합물의 용도 |
US6689759B1 (en) | 1998-02-12 | 2004-02-10 | G. D. Searle & Co. | Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy |
EP1173161A2 (en) | 1999-02-12 | 2002-01-23 | G.D. SEARLE & CO. | Glucamine compounds for treating hepatitis virus infections |
US6545021B1 (en) | 1999-02-12 | 2003-04-08 | G.D. Searle & Co. | Use of substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds for treating hepatitis virus infections |
WO2001060366A1 (en) * | 2000-02-14 | 2001-08-23 | Pharmacia Corporation | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds for treating hepatitis virus infections |
JP2008519840A (ja) * | 2004-11-10 | 2008-06-12 | ジェンザイム・コーポレイション | 糖尿病の処置方法 |
AT502145B1 (de) * | 2005-03-24 | 2012-01-15 | Univ Graz Tech | Glycosidase-hemmendes iminoalditol |
PL2032134T3 (pl) | 2006-05-09 | 2015-11-30 | Genzyme Corp | Sposoby leczenia stłuszczeniowej choroby wątroby obejmujące hamowanie syntezy glikosfingolipidów |
JP5241709B2 (ja) * | 2006-05-24 | 2013-07-17 | ユナイテッド セラピューティクス コーポレーション | デオキシノジリマイシンおよびd−アラビニトールのアナログおよび使用方法 |
US8097728B2 (en) * | 2007-04-30 | 2012-01-17 | Philadelphia Health & Education Corporation | Iminosugar compounds with antiflavirus activity |
EP2594564B1 (en) * | 2007-05-31 | 2016-09-28 | Genzyme Corporation | 2-acylaminopropanol-type glucosylceramide synthase inhibitors |
RU2517345C9 (ru) | 2007-10-05 | 2014-08-20 | Гензим Корпорейшн | Способ лечения поликистозных заболеваний почек с помощью производных церамида |
CA2731685A1 (en) | 2008-07-28 | 2010-02-04 | Genzyme Corporation | Glucosylceramide synthase inhibition for the treatment of collapsing glomerulopathy and other glomerular disease |
KR101687039B1 (ko) | 2008-10-03 | 2016-12-15 | 젠자임 코포레이션 | 2-아실아미노프로판올형 글루코실세라미드 합성효소 억제제 |
BR112018072298A2 (pt) | 2016-05-02 | 2019-02-12 | Florida State University Research Foundation, Inc. | tratamento de infecções pelo vírus da zika usando inibidores da alfa-glicosidase |
WO2021168483A2 (en) | 2020-02-21 | 2021-08-26 | Florida State University Research Foundation, Inc. | Treatment of human coronavirus infections using alpha-glucosidase glycoprotein processing inhibitors |
CN115867534A (zh) * | 2020-05-07 | 2023-03-28 | 阿勒克图治疗公司 | 非溶酶体葡糖神经酰胺酶抑制剂及其用途 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5282710A (en) * | 1975-12-29 | 1977-07-11 | Nippon Shinyaku Co Ltd | Extraction of effective drug component from mulberry |
DE2735316C3 (de) * | 1977-08-05 | 1981-01-29 | Basf Ag, 6700 Ludwigshafen | Verfahren zur Herstellung von nadeiförmigen, ferrimagnetischen Eisenoxiden |
-
1979
- 1979-03-21 GB GB7909865A patent/GB2020278B/en not_active Expired
- 1979-04-12 DE DE2915037A patent/DE2915037C3/de not_active Expired
- 1979-04-25 FR FR7910559A patent/FR2424910A1/fr active Granted
- 1979-04-27 US US06/033,839 patent/US4533668A/en not_active Expired - Lifetime
- 1979-05-01 DK DK178379A patent/DK151623C/da not_active IP Right Cessation
- 1979-05-02 SE SE7903817A patent/SE436874B/sv not_active IP Right Cessation
- 1979-05-02 NL NLAANVRAGE7903421,A patent/NL175820C/xx not_active IP Right Cessation
- 1979-05-02 IT IT48904/79A patent/IT1116820B/it active
- 1979-05-03 CH CH415879A patent/CH642629A5/de not_active IP Right Cessation
-
1984
- 1984-05-11 SE SE8402550A patent/SE451016B/sv not_active IP Right Cessation
- 1984-05-11 SE SE8402551A patent/SE451017B/sv not_active IP Right Cessation
- 1984-05-11 SE SE8402549A patent/SE451015B/sv not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CH642629A5 (de) | 1984-04-30 |
NL175820C (nl) | 1985-01-02 |
SE7903817L (sv) | 1979-11-04 |
DE2915037C3 (de) | 1981-11-05 |
SE8402551L (sv) | 1984-05-11 |
SE8402551D0 (sv) | 1984-05-11 |
SE8402550D0 (sv) | 1984-05-11 |
SE451016B (sv) | 1987-08-24 |
DE2915037A1 (de) | 1979-11-08 |
DK151623C (da) | 1988-07-18 |
SE8402549L (sv) | 1984-05-11 |
DK151623B (da) | 1987-12-21 |
DK178379A (da) | 1979-11-04 |
US4533668A (en) | 1985-08-06 |
DE2915037B2 (de) | 1981-01-29 |
FR2424910A1 (fr) | 1979-11-30 |
IT1116820B (it) | 1986-02-10 |
GB2020278A (en) | 1979-11-14 |
FR2424910B1 (sv) | 1981-12-11 |
SE436874B (sv) | 1985-01-28 |
GB2020278B (en) | 1983-02-23 |
SE451015B (sv) | 1987-08-24 |
SE8402550L (sv) | 1984-05-11 |
NL175820B (nl) | 1984-08-01 |
NL7903421A (nl) | 1979-11-06 |
IT7948904A0 (it) | 1979-05-02 |
SE451017B (sv) | 1987-08-24 |
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Legal Events
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