DK178379A - Fremgangsmaade til fremstilling af n-substituerede moranolinderivater eller syreadditionssalte deraf - Google Patents
Fremgangsmaade til fremstilling af n-substituerede moranolinderivater eller syreadditionssalte derafInfo
- Publication number
- DK178379A DK178379A DK178379A DK178379A DK178379A DK 178379 A DK178379 A DK 178379A DK 178379 A DK178379 A DK 178379A DK 178379 A DK178379 A DK 178379A DK 178379 A DK178379 A DK 178379A
- Authority
- DK
- Denmark
- Prior art keywords
- substituted
- procedure
- preparation
- additional salts
- acid additional
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5360378 | 1978-05-03 | ||
JP53053603A JPS5943947B2 (ja) | 1978-05-03 | 1978-05-03 | N−置換モラノリン誘導体 |
JP8260678 | 1978-07-06 | ||
JP8260678A JPS5943948B2 (ja) | 1978-07-06 | 1978-07-06 | 置換モラノリン誘導体 |
JP12066178A JPS5943949B2 (ja) | 1978-09-29 | 1978-09-29 | モラノリンのn−置換誘導体 |
JP12066178 | 1978-09-29 | ||
JP571479 | 1979-01-20 | ||
JP571479A JPS6026387B2 (ja) | 1979-01-20 | 1979-01-20 | シンナミルモラノリン誘導体 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK178379A true DK178379A (da) | 1979-11-04 |
DK151623B DK151623B (da) | 1987-12-21 |
DK151623C DK151623C (da) | 1988-07-18 |
Family
ID=27454348
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK178379A DK151623C (da) | 1978-05-03 | 1979-05-01 | Analogifremgangsmaade til fremstilling af n-substituerede moranolinderivater eller farmaceutisk acceptable syreadditionssalte deraf |
Country Status (9)
Country | Link |
---|---|
US (1) | US4533668A (da) |
CH (1) | CH642629A5 (da) |
DE (1) | DE2915037C3 (da) |
DK (1) | DK151623C (da) |
FR (1) | FR2424910A1 (da) |
GB (1) | GB2020278B (da) |
IT (1) | IT1116820B (da) |
NL (1) | NL175820C (da) |
SE (4) | SE436874B (da) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO154918C (no) * | 1977-08-27 | 1987-01-14 | Bayer Ag | Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin. |
DE2925943A1 (de) * | 1979-06-27 | 1981-01-29 | Bayer Ag | 1-alkadien-2,4-yl-2-hydroxymethyl3,4,5-trihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
DE2942365A1 (de) * | 1979-10-19 | 1981-05-14 | Bayer Ag, 5090 Leverkusen | 2-hydroxyalkyl-3,4,5-trihydroxy-(pi)-peridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
DE3007078A1 (de) * | 1980-02-26 | 1981-09-10 | Bayer Ag, 5090 Leverkusen | Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel sowie in der tierernaehrung |
JP2504000B2 (ja) * | 1986-09-02 | 1996-06-05 | 日本新薬株式会社 | グルコシルモラノリン誘導体 |
JPS6461459A (en) * | 1987-08-28 | 1989-03-08 | Nippon Shinyaku Co Ltd | Moranoline derivative |
GB8827701D0 (en) * | 1987-12-09 | 1988-12-29 | Nippon Shinyaku Co Ltd | Thrombolytic &c compositions |
US5192772A (en) * | 1987-12-09 | 1993-03-09 | Nippon Shinyaku Co. Ltd. | Therapeutic agents |
US4985445A (en) * | 1988-02-12 | 1991-01-15 | Meiji Seika Kaisha, Ltd. | Cancer cell metastasis inhibitors and novel compounds |
EP0350012A3 (en) * | 1988-07-08 | 1990-09-05 | Meiji Seika Kaisha Ltd. | Antiviral composition |
DK0566557T3 (da) * | 1992-04-01 | 1996-11-04 | Searle & Co | 2- og 3-amino- og azidoderivater af 1,5- iminosukkere som antivirale forbindelser |
US5206251A (en) * | 1992-04-01 | 1993-04-27 | G. D. Searle & Co. | 2- and 3- amino and azido derivatives of 1,5-iminosugars |
US5331096A (en) * | 1992-04-01 | 1994-07-19 | G. D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
US5216168A (en) * | 1992-04-01 | 1993-06-01 | G. D. Searle & Co. | 2- and 3- amino and azido derivatives of 1,5-iminosugars |
US5342951A (en) * | 1992-04-01 | 1994-08-30 | G.D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
US5258518A (en) * | 1992-04-01 | 1993-11-02 | G. D. Searle & Co. | 2-substituted tertiary carbinol derivatives of deoxynojirimycin |
US5268482A (en) * | 1992-04-01 | 1993-12-07 | G. D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
US6291657B1 (en) | 1993-05-13 | 2001-09-18 | Monsanto Company | Deoxygalactonojirimycin derivatives |
US5399567A (en) * | 1993-05-13 | 1995-03-21 | Monsanto Company | Method of treating cholera |
US5798366A (en) * | 1993-05-13 | 1998-08-25 | Monsanto Company | Method for treatment of CNS-involved lysosomal storage diseases |
US20030100532A1 (en) * | 1997-02-14 | 2003-05-29 | Gary S. Jacob | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections |
ES2216327T3 (es) | 1997-11-10 | 2004-10-16 | G.D. SEARLE & CO. | Uso de iminoazucares alquilados para tratar la resistencia a multiples a farmacos. |
US6689759B1 (en) | 1998-02-12 | 2004-02-10 | G. D. Searle & Co. | Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy |
CA2319713C (en) | 1998-02-12 | 2012-06-26 | G.D. Searle & Co. | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds for treating hepatitis virus infections |
CA2362785A1 (en) | 1999-02-12 | 2001-02-08 | G.D. Searle & Co. | Glucamine compounds for treating hepatitis virus infections |
EP1165080A2 (en) | 1999-02-12 | 2002-01-02 | G.D. SEARLE & CO. | Use of substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds for treating hepatitis virus infections |
AU2001236938A1 (en) * | 2000-02-14 | 2001-08-27 | Pharmacia Corporation | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds for treating hepatitis virus infections |
US8003617B2 (en) * | 2004-11-10 | 2011-08-23 | Genzyme Corporation | Methods of treating diabetes mellitus |
AT502145B1 (de) * | 2005-03-24 | 2012-01-15 | Univ Graz Tech | Glycosidase-hemmendes iminoalditol |
PT2032134E (pt) | 2006-05-09 | 2015-10-07 | Genzyme Corp | Métodos de tratamento da doença do fígado gorduroso |
JP5241709B2 (ja) * | 2006-05-24 | 2013-07-17 | ユナイテッド セラピューティクス コーポレーション | デオキシノジリマイシンおよびd−アラビニトールのアナログおよび使用方法 |
US8097728B2 (en) * | 2007-04-30 | 2012-01-17 | Philadelphia Health & Education Corporation | Iminosugar compounds with antiflavirus activity |
EP2594565B1 (en) | 2007-05-31 | 2018-10-24 | Genzyme Corporation | 2-acylaminopropanol-type glucosylceramide synthase inhibitors |
BRPI0823522A2 (pt) * | 2007-10-05 | 2014-01-07 | Genzyme Corp | Uso de um composto derivado de ceramida |
WO2010014554A1 (en) | 2008-07-28 | 2010-02-04 | Genzyme Corporation | Glucosylceramide synthase inhibition for the treatment of collapsing glomerulopathy and other glomerular disease |
WO2010039256A1 (en) * | 2008-10-03 | 2010-04-08 | Genzyme Corporation | 2-acylaminopropoanol-type glucosylceramide synthase inhibitors |
WO2017192599A1 (en) | 2016-05-02 | 2017-11-09 | Florida State University Research Foundation, Inc. | Treatment of zika virus infections using alpha-glucosidase inhibitors |
US11369592B2 (en) | 2020-02-21 | 2022-06-28 | Florida State University Research Foundation, Inc. | Treatment of human coronavirus infections using alpha-glucosidase glycoprotein processing inhibitors |
PE20231424A1 (es) * | 2020-05-07 | 2023-09-13 | Alectos Therapeutics Inc | Inhibidores de glucosilceramidasa no lisosomal y los usos de los mismos |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5282710A (en) * | 1975-12-29 | 1977-07-11 | Nippon Shinyaku Co Ltd | Extraction of effective drug component from mulberry |
DE2735316C3 (de) * | 1977-08-05 | 1981-01-29 | Basf Ag, 6700 Ludwigshafen | Verfahren zur Herstellung von nadeiförmigen, ferrimagnetischen Eisenoxiden |
-
1979
- 1979-03-21 GB GB7909865A patent/GB2020278B/en not_active Expired
- 1979-04-12 DE DE2915037A patent/DE2915037C3/de not_active Expired
- 1979-04-25 FR FR7910559A patent/FR2424910A1/fr active Granted
- 1979-04-27 US US06/033,839 patent/US4533668A/en not_active Expired - Lifetime
- 1979-05-01 DK DK178379A patent/DK151623C/da not_active IP Right Cessation
- 1979-05-02 SE SE7903817A patent/SE436874B/sv not_active IP Right Cessation
- 1979-05-02 NL NLAANVRAGE7903421,A patent/NL175820C/xx not_active IP Right Cessation
- 1979-05-02 IT IT48904/79A patent/IT1116820B/it active
- 1979-05-03 CH CH415879A patent/CH642629A5/de not_active IP Right Cessation
-
1984
- 1984-05-11 SE SE8402549A patent/SE451015B/sv not_active IP Right Cessation
- 1984-05-11 SE SE8402551A patent/SE451017B/sv not_active IP Right Cessation
- 1984-05-11 SE SE8402550A patent/SE451016B/sv not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK151623C (da) | 1988-07-18 |
SE8402551D0 (sv) | 1984-05-11 |
IT1116820B (it) | 1986-02-10 |
DE2915037C3 (de) | 1981-11-05 |
SE7903817L (sv) | 1979-11-04 |
SE8402550L (sv) | 1984-05-11 |
DE2915037B2 (de) | 1981-01-29 |
US4533668A (en) | 1985-08-06 |
FR2424910A1 (fr) | 1979-11-30 |
SE8402549D0 (sv) | 1984-05-11 |
CH642629A5 (de) | 1984-04-30 |
NL7903421A (nl) | 1979-11-06 |
IT7948904A0 (it) | 1979-05-02 |
FR2424910B1 (da) | 1981-12-11 |
GB2020278A (en) | 1979-11-14 |
SE436874B (sv) | 1985-01-28 |
SE8402551L (sv) | 1984-05-11 |
DK151623B (da) | 1987-12-21 |
DE2915037A1 (de) | 1979-11-08 |
SE8402550D0 (sv) | 1984-05-11 |
NL175820C (nl) | 1985-01-02 |
GB2020278B (en) | 1983-02-23 |
SE451016B (sv) | 1987-08-24 |
SE8402549L (sv) | 1984-05-11 |
SE451017B (sv) | 1987-08-24 |
NL175820B (nl) | 1984-08-01 |
SE451015B (sv) | 1987-08-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |