ATE331515T1 - Verwendung von n-substituirten-1,5-dideoxy-1,5- imino-d-glucitolen zur behandlung von hepatitis infektionen - Google Patents
Verwendung von n-substituirten-1,5-dideoxy-1,5- imino-d-glucitolen zur behandlung von hepatitis infektionenInfo
- Publication number
- ATE331515T1 ATE331515T1 AT99908079T AT99908079T ATE331515T1 AT E331515 T1 ATE331515 T1 AT E331515T1 AT 99908079 T AT99908079 T AT 99908079T AT 99908079 T AT99908079 T AT 99908079T AT E331515 T1 ATE331515 T1 AT E331515T1
- Authority
- AT
- Austria
- Prior art keywords
- dideoxy
- imino
- substituted
- glucitolen
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7450898P | 1998-02-12 | 1998-02-12 | |
US09/023,401 US20030100532A1 (en) | 1997-02-14 | 1998-02-12 | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE331515T1 true ATE331515T1 (de) | 2006-07-15 |
Family
ID=26697090
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99908079T ATE331515T1 (de) | 1998-02-12 | 1999-02-12 | Verwendung von n-substituirten-1,5-dideoxy-1,5- imino-d-glucitolen zur behandlung von hepatitis infektionen |
Country Status (16)
Country | Link |
---|---|
US (2) | US6809083B1 (de) |
EP (1) | EP1061922B9 (de) |
JP (1) | JP2002502875A (de) |
KR (1) | KR20010040937A (de) |
AT (1) | ATE331515T1 (de) |
AU (2) | AU762125B2 (de) |
BR (1) | BR9907882A (de) |
CA (1) | CA2319713C (de) |
DE (1) | DE69932154T2 (de) |
EA (1) | EA004705B1 (de) |
ES (1) | ES2272054T3 (de) |
ID (1) | ID27290A (de) |
MY (1) | MY122185A (de) |
TR (1) | TR200002323T2 (de) |
TW (1) | TWI222867B (de) |
WO (1) | WO1999040916A1 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030100532A1 (en) * | 1997-02-14 | 2003-05-29 | Gary S. Jacob | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections |
AU762125B2 (en) | 1998-02-12 | 2003-06-19 | G.D. Searle & Co. | Use of (N)-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds for treating hepatitis virus infections |
US6689759B1 (en) | 1998-02-12 | 2004-02-10 | G. D. Searle & Co. | Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy |
EP1165080A2 (de) * | 1999-02-12 | 2002-01-02 | G.D. SEARLE & CO. | Verwendung von substituierten 1,5-dideoxy-1,5-imino-d-glucitol-derivaten zur behandlung von hepatitis-virus-infektionen |
AU3858600A (en) * | 1999-02-12 | 2001-02-19 | G.D. Searle & Co. | Glucamine compounds for treating hepatitis virus infections |
DE60037664T2 (de) * | 1999-08-10 | 2008-12-24 | The Chancellor, Masters And Scholars Of The University Of Oxford | Langkettige n-alkyl verbindungen und deren oxa-derivate zur verwendung als anitvirale mittel |
AU2001236938A1 (en) * | 2000-02-14 | 2001-08-27 | Pharmacia Corporation | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds for treating hepatitis virus infections |
AU2013203974B2 (en) * | 2000-05-23 | 2016-06-02 | Idenix Pharmaceuticals, Inc. | Methods and compositions for treating hepatitis C virus |
WO2001092282A2 (en) | 2000-05-26 | 2001-12-06 | Idenix (Cayman) Limited | Methods and compositions for treating flaviviruses and pestiviruses |
WO2003037265A2 (en) * | 2001-10-30 | 2003-05-08 | Thomas Jefferson University | Method of treating viral infections |
WO2006085141A2 (en) * | 2004-08-13 | 2006-08-17 | Migenix Inc. | Compositions and methods for treating or preventing hepadnaviridae infection |
WO2006133447A1 (en) * | 2005-06-08 | 2006-12-14 | Amicus Therapeutics, Inc. | Crystalline sugar compositions and method of making |
WO2006133448A1 (en) * | 2005-06-08 | 2006-12-14 | Amicus Therapeutics, Inc. | Stabilization of triflated compounds |
WO2008045015A1 (en) * | 2005-06-08 | 2008-04-17 | Amicus Therapeutics, Inc. | Imino and amino sugar purification |
US7473683B2 (en) | 2005-09-14 | 2009-01-06 | The Board Of Trustees Of The Leland Stanford Junior University | Nonpolar thymidine analogs |
CN101489554A (zh) * | 2006-05-24 | 2009-07-22 | 联合治疗公司 | 脱氧吉瑞霉素和d-阿拉伯胶素醇类似物及使用方法 |
EP2356990A3 (de) | 2006-08-02 | 2011-10-19 | University of Oxford | Liposomen-Behandlung von Virusinfektionen |
US8097728B2 (en) * | 2007-04-30 | 2012-01-17 | Philadelphia Health & Education Corporation | Iminosugar compounds with antiflavirus activity |
KR20100127842A (ko) * | 2008-03-26 | 2010-12-06 | 유니버시티 오브 옥스퍼드 | 소포체 표적화 리포좀 |
CA2753195C (en) | 2009-02-23 | 2015-06-02 | United Therapeutics Corporation | Iminosugars and methods of treating viral diseases |
WO2010109330A2 (en) * | 2009-03-27 | 2010-09-30 | University Of Oxford | Cholesterol level lowering liposomes |
EP2440205B1 (de) | 2009-06-12 | 2014-08-27 | United Therapeutics Corporation | Iminozucker zur verwendung in der behandlung von bunyaviralen und togaviralen erkrankungen |
CN102625801B (zh) * | 2009-09-04 | 2015-09-09 | 联合治疗公司 | 治疗痘病毒感染的方法 |
IN2014MN02539A (de) | 2012-06-06 | 2015-07-24 | Unither Virology Llc | |
SG11201703330YA (en) | 2014-11-05 | 2017-05-30 | Emergent Virology Llc | Iminosugars useful for the treatment of viral diseases |
CA3009996A1 (en) * | 2016-01-08 | 2017-07-13 | Arbutus Biopharma Corporation | Therapeutic compositions and methods for treating hepatitis b |
Family Cites Families (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
YU33730B (en) | 1967-04-18 | 1978-02-28 | Farmaceutici Italia | Process for preparing a novel antibiotic substance and salts thereof |
GB1555654A (en) | 1977-06-25 | 1979-11-14 | Exxon Research Engineering Co | Agricultural burner apparatus |
US4065562A (en) | 1975-12-29 | 1977-12-27 | Nippon Shinyaku Co., Ltd. | Method and composition for reducing blood glucose levels |
US4012448A (en) | 1976-01-15 | 1977-03-15 | Stanford Research Institute | Synthesis of adriamycin and 7,9-epiadriamycin |
NO154918C (no) | 1977-08-27 | 1987-01-14 | Bayer Ag | Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin. |
GB2020278B (en) | 1978-05-03 | 1983-02-23 | Nippon Shinyaku Co Ltd | Moranoline dervitives |
JPS5562004A (en) | 1978-11-02 | 1980-05-10 | Kureha Chem Ind Co Ltd | Control agent against plant viral disease |
US4327725A (en) | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
DE3049446A1 (de) | 1980-12-30 | 1982-07-29 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von 1,5-didesoxy-1,5-imino-d-glucitol und dessen n-derivaten |
ZA822995B (en) | 1981-05-21 | 1983-12-28 | Wyeth John & Brother Ltd | Slow release pharmaceutical composition |
US4765989A (en) | 1983-05-11 | 1988-08-23 | Alza Corporation | Osmotic device for administering certain drugs |
US4612008A (en) | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
US4783337A (en) | 1983-05-11 | 1988-11-08 | Alza Corporation | Osmotic system comprising plurality of members for dispensing drug |
JPS63501925A (ja) | 1985-12-23 | 1988-08-04 | フレツド ハツチンソン キヤンサ− リサ−チ センタ− | レトロウイルスの複製、感染及び疾病誘発の制御 |
GB2186485B (en) | 1986-02-13 | 1988-09-07 | Ethical Pharma Ltd | Slow release formulation |
DE3611841A1 (de) | 1986-04-09 | 1987-10-15 | Bayer Ag | Verfahren zur herstellung von 1-desoxynojirimycin und dessen n-derivaten |
CA1316459C (en) | 1987-12-21 | 1993-04-20 | Raymond Allen Dwek | Method of inhibiting virus |
US4849430A (en) * | 1988-03-09 | 1989-07-18 | Monsanto Company | Method of inhibiting virus |
FI101344B (fi) | 1988-03-31 | 1998-06-15 | Tanabe Seiyaku Co | Menetelmä valmistaa valmiste, josta kontrolloidusti vapautuu farmaseut tisesti aktiivista ainetta |
US5041441A (en) | 1988-04-04 | 1991-08-20 | The Regents Of The University Of Michigan | Method of chemotherapy using 1-phenyl-2-decanoylamino-3-morpholino-1-propanol |
EP0350012A3 (de) | 1988-07-08 | 1990-09-05 | Meiji Seika Kaisha Ltd. | Antivirale Zusammensetzung |
US5144037A (en) * | 1988-11-03 | 1992-09-01 | G. D. Searle & Co. | 1,5-dideoxy-1,5-imino-d-glucitol derivatives |
US5310745A (en) | 1988-11-03 | 1994-05-10 | G. D. Searle & Co. | Antiviral compounds |
US5003072A (en) * | 1988-11-03 | 1991-03-26 | G. D. Searle & Co. | 1,5-dideoxy-1,5-imino-D-glucitol derivatives |
US5221746A (en) * | 1988-11-03 | 1993-06-22 | G. D. Searle & Co. | 1,5-dideoxy-1,5-imino-D-glucitol derivatives |
US4957926A (en) | 1988-12-22 | 1990-09-18 | Monsanto Company | Method of treating herpesviruses |
US5011829A (en) | 1989-06-02 | 1991-04-30 | G. D. Searle & Co. | Pharmaceutical composition and method of inhibiting virus |
US5030638A (en) * | 1990-02-26 | 1991-07-09 | G. D. Searle & Co. | Method of antiviral enhancement |
DE4009561A1 (de) * | 1990-03-24 | 1991-09-26 | Bayer Ag | Neue desoxynojirimycinderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
US5536732A (en) | 1990-04-27 | 1996-07-16 | Merrell Pharmaceuticals Inc. | N-derivatives of 1-deoxy nojirimycin |
US5151519A (en) | 1990-05-07 | 1992-09-29 | G. D. Searle & Co. | Process for the preparation of 1,5-(alkylimino)-1,5-dideoxy-d-glucitol and derivatives thereof |
JP3162123B2 (ja) | 1990-09-20 | 2001-04-25 | モンサント カンパニー | N−置換−1−デオキシノジリマイシンの製造方法 |
US5444063A (en) * | 1990-12-05 | 1995-08-22 | Emory University | Enantiomerically pure β-D-dioxolane nucleosides with selective anti-Hepatitis B virus activity |
US5190765A (en) | 1991-06-27 | 1993-03-02 | Alza Corporation | Therapy delayed |
ZA931934B (en) | 1992-03-18 | 1993-03-18 | Us Bioscience | Compostitions of N-(phosphonoacetyl)-L-aspartic acid and methods of their use as broad spectrum antivirals |
IL105090A (en) | 1992-03-18 | 1998-08-16 | Us Bioscience | Acid N) phosphonoacetyl (Aspartic L in a broad spectrum antiviral agent |
US5258518A (en) | 1992-04-01 | 1993-11-02 | G. D. Searle & Co. | 2-substituted tertiary carbinol derivatives of deoxynojirimycin |
US5331096A (en) | 1992-04-01 | 1994-07-19 | G. D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
WO1994004546A1 (en) | 1992-08-14 | 1994-03-03 | Nippon Shinyaku Co., Ltd. | Moranoline derivative |
FR2700267B1 (fr) | 1993-01-13 | 1995-03-17 | Oreal | N-acyl amino déoxy alditols, et leur utilisation dans des compositions cosmétiques ou dermopharmaceutiques. |
DE69419601T2 (de) | 1993-03-17 | 1999-12-02 | Kao Corp | Aminderivate und sie enthaltende dermatologische zubereitungen |
US5399567A (en) | 1993-05-13 | 1995-03-21 | Monsanto Company | Method of treating cholera |
AU7518694A (en) | 1993-08-20 | 1995-03-21 | G.D. Searle & Co. | Retroviral protease inhibitors and combinations thereof |
US6093702A (en) * | 1993-12-20 | 2000-07-25 | The United States Of America As Represented By The Department Of Health And Human Services | Mixtures of dideoxy-nucleosides and hydroxycarbamide for inhibiting retroviral spread |
DE69421828T2 (de) * | 1994-01-13 | 2000-04-20 | Searle & Co | Verwendung von 1,5-dideoxy-1,5-imino-d-glucitol n-alkylderivaten zur behandlung von hepatitis b infektionen |
WO1995022975A1 (en) * | 1994-02-25 | 1995-08-31 | G.D. Searle & Co. | Use of 1-deoxynojirimycin and its derivatives for treating mammals infected with respiratory syncytial virus |
US5451679A (en) | 1994-03-08 | 1995-09-19 | G. D. Searle & Co. | 2-chloro and 2-bromo derivatives of 1,5-iminosugars |
US5703058A (en) * | 1995-01-27 | 1997-12-30 | Emory University | Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent |
FR2731150B1 (fr) | 1995-03-03 | 1997-04-18 | Oreal | Utilisation de composes amphiphiles en tant qu'agent epaississant de milieux non aqueux |
US5763470A (en) | 1995-06-07 | 1998-06-09 | Sugen Inc. | Benzopyran compounds and methods for their use |
WO1997000881A1 (en) | 1995-06-22 | 1997-01-09 | Nippon Shinyaku Co., Ltd. | Moranoline derivatives |
JP2001512462A (ja) | 1997-02-14 | 2001-08-21 | ジー.ディー.サール アンド カンパニー | N−置換−1,5−ジデオキシ−1,5−イミノ−d−グルシトール化合物の、肝炎ウイルス感染の治療のための組み合わせ療法における使用 |
US6465487B1 (en) | 1997-12-11 | 2002-10-15 | Synergy Pharmaceuticals, Inc. | Inhibition of membrane-associated viral replication |
AU762125B2 (en) | 1998-02-12 | 2003-06-19 | G.D. Searle & Co. | Use of (N)-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds for treating hepatitis virus infections |
-
1999
- 1999-02-12 AU AU27595/99A patent/AU762125B2/en not_active Ceased
- 1999-02-12 TR TR2000/02323T patent/TR200002323T2/xx unknown
- 1999-02-12 AT AT99908079T patent/ATE331515T1/de not_active IP Right Cessation
- 1999-02-12 JP JP2000531168A patent/JP2002502875A/ja active Pending
- 1999-02-12 EP EP99908079A patent/EP1061922B9/de not_active Expired - Lifetime
- 1999-02-12 ID IDW20001493A patent/ID27290A/id unknown
- 1999-02-12 DE DE69932154T patent/DE69932154T2/de not_active Expired - Lifetime
- 1999-02-12 KR KR1020007008852A patent/KR20010040937A/ko not_active Application Discontinuation
- 1999-02-12 WO PCT/US1999/001874 patent/WO1999040916A1/en active IP Right Grant
- 1999-02-12 EA EA200000836A patent/EA004705B1/ru not_active IP Right Cessation
- 1999-02-12 MY MYPI99000516A patent/MY122185A/en unknown
- 1999-02-12 US US09/249,220 patent/US6809083B1/en not_active Expired - Lifetime
- 1999-02-12 CA CA2319713A patent/CA2319713C/en not_active Expired - Fee Related
- 1999-02-12 ES ES99908079T patent/ES2272054T3/es not_active Expired - Lifetime
- 1999-02-12 BR BR9907882-1A patent/BR9907882A/pt not_active Application Discontinuation
- 1999-04-07 TW TW088102296A patent/TWI222867B/zh not_active IP Right Cessation
-
2003
- 2003-09-18 AU AU2003248024A patent/AU2003248024A1/en not_active Abandoned
-
2004
- 2004-08-03 US US10/910,197 patent/US20050267153A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2319713C (en) | 2012-06-26 |
JP2002502875A (ja) | 2002-01-29 |
CA2319713A1 (en) | 1999-08-19 |
US6809083B1 (en) | 2004-10-26 |
AU2003248024A1 (en) | 2003-10-30 |
ES2272054T3 (es) | 2007-04-16 |
AU762125B2 (en) | 2003-06-19 |
EA004705B1 (ru) | 2004-06-24 |
EP1061922B1 (de) | 2006-06-28 |
TWI222867B (en) | 2004-11-01 |
EP1061922B9 (de) | 2007-03-07 |
AU2759599A (en) | 1999-08-30 |
DE69932154T2 (de) | 2007-05-31 |
US20050267153A1 (en) | 2005-12-01 |
KR20010040937A (ko) | 2001-05-15 |
DE69932154D1 (de) | 2006-08-10 |
EA200000836A1 (ru) | 2001-04-23 |
TR200002323T2 (tr) | 2000-12-21 |
WO1999040916A1 (en) | 1999-08-19 |
MY122185A (en) | 2006-03-31 |
EP1061922A1 (de) | 2000-12-27 |
BR9907882A (pt) | 2000-10-17 |
ID27290A (id) | 2001-03-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE331515T1 (de) | Verwendung von n-substituirten-1,5-dideoxy-1,5- imino-d-glucitolen zur behandlung von hepatitis infektionen | |
DE60039729D1 (de) | N-(8,8,8-Trifluorooctyl)-1,5-dideoxy-1,5-imino-D-glucitol zur Behandlung von Hepatitis-Virus-Infektionen | |
CA2119006A1 (en) | Composition and method of treating hepatitis c | |
KR0179637B1 (en) | Diaromatic substituted compounds as anti-hiv-1 agents | |
EP1435974A4 (de) | Verfahren und zusamemnsetzungen zur behandlung des hepatitis-c-virus mit 4'-modifizierten nucleosiden | |
BR0309581A (pt) | Derivados de nucleosìdeo para tratamento de infecção por vìrus de hepatite c | |
DE69925256D1 (de) | Trisubstituierte 1,3,5-triazine derivate zur behandlung von hiv infektionen | |
EP1128832A4 (de) | Verbindungen, zusammenstellungen und methoden zur phophylaxe und behandlung von viralen infektionen und damit verbundenen erkrankungen | |
DE69830241D1 (de) | Verwendung von n-substituierten 1,5-dideoxy-1,5-imino-d-glucitol verbindungen in der kombinationstherapie der vom hepatitisvirus verursachten infektionen | |
MY155218A (en) | Small molecules useful in the treatment of inflammatory disease | |
IL136690A0 (en) | Inhibition of raf kinase using symmetrical and unsymmetrical substituted diphenyl ureas | |
TR200003011T2 (tr) | Yeni dihidropirimidinler. | |
MY141594A (en) | 3'-PRODRUGS OF 2'-DEOXY-ß-L-NUCLEOSIDES | |
DE69811062D1 (de) | Polyaromatische antivirale zusammensetzungen | |
YU60900A (sh) | Novi kristalni oblici antivirusnog benzimidazolskog jedinjenja | |
ZA943896B (en) | Pharmaceutical agents for treatment of emesis | |
ATE77234T1 (de) | Aromatische verbindungen mit amider struktur, derivate von aminobenzoesaeuren, hydroxybenzoesaeuren, zimtsaeuren, urocansaeuren und benzimidazolen, die uvb und/oder uva absorbieren. | |
ES2036526T3 (es) | Composiciones de interferon. | |
ES2175356T3 (es) | Uso de (+)-alfa-(2,3-dimetoxifenil)-1-[2-(4 fluorofenil)et il[-4- piperidinmetanol en el tratamiento de trastornos depresivos y trastornos bipolares. | |
ES2102772T3 (es) | Compuesto citotoxico y antiviral. | |
DE69838980D1 (de) | Kombination von product r mit einem antiviralen mittel in der behandlung von hiv infektionen | |
DK0393530T3 (da) | 5,11-Dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-oner og -thioner og deres anvendelse til forebyggelse eller behandling af AIDS | |
AR019532A1 (es) | COMPOSICIoN FARMACÉUTICA DEL COMPUESTO 1,5-DIDEOXI-1,5-IMIN-D-GLUCITOL N-SUSTITUIDO | |
ZA871140B (en) | Synergistic chemical compositions for treating salmonellosis | |
TR200100043T2 (tr) | Ağrı tedavisinde ilaç hazırlanmasında tetra hidropiridin(veya 4-Hidroksipipeidin)-butilozollerin türevleri |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |