BR9907882A - Uso de compostos de 1,5-didesóxi-1,5-imino-d-glucitol n-substituìdos para o tratamento de infecções de vìrus de hepatite - Google Patents
Uso de compostos de 1,5-didesóxi-1,5-imino-d-glucitol n-substituìdos para o tratamento de infecções de vìrus de hepatiteInfo
- Publication number
- BR9907882A BR9907882A BR9907882-1A BR9907882A BR9907882A BR 9907882 A BR9907882 A BR 9907882A BR 9907882 A BR9907882 A BR 9907882A BR 9907882 A BR9907882 A BR 9907882A
- Authority
- BR
- Brazil
- Prior art keywords
- dideoxy
- imino
- hepatitis virus
- virus infections
- unsubstituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
Abstract
Patente de Invenção: <B>"USO DE COMPOSTOS DE 1,5-DIDESóXI-1,5-IMINO-D-GLUCITOL N-SUBSTITUìDOS PARA O TRATAMENTO DE INFECçõES DE VìRUS DE HEPATITE"<D>. Providos são métodos e composições para o tratamento de infecções de vírus de hepatite em mamíferos, especialmente seres humanos. Os métodos compreende (1) administração de compostos 1,5-didesóxi-,1,5-imino-D-glucitol N-substituídos sozinhos ou em combinação com agentes antivirais de nucleosídeo, agentes antivirais de nucleotídeo, suas misturas, ou agentes de imunomodulação/imunoestimulação, ou (2) administracão de compostos 1,5-didesóxi-,1,5-imino-D-glucitol N-substituídos sozinhos ou em combinação com agentes antivirais de nucleosídeo, agentes antivirais de nucleotídeo ou suas misturas e agentes de imunomodulação/imunoestimulante.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7450898P | 1998-02-12 | 1998-02-12 | |
US09/023,401 US20030100532A1 (en) | 1997-02-14 | 1998-02-12 | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections |
PCT/US1999/001874 WO1999040916A1 (en) | 1998-02-12 | 1999-02-12 | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds for treating hepatitis virus infections |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9907882A true BR9907882A (pt) | 2000-10-17 |
Family
ID=26697090
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9907882-1A BR9907882A (pt) | 1998-02-12 | 1999-02-12 | Uso de compostos de 1,5-didesóxi-1,5-imino-d-glucitol n-substituìdos para o tratamento de infecções de vìrus de hepatite |
Country Status (16)
Country | Link |
---|---|
US (2) | US6809083B1 (pt) |
EP (1) | EP1061922B9 (pt) |
JP (1) | JP2002502875A (pt) |
KR (1) | KR20010040937A (pt) |
AT (1) | ATE331515T1 (pt) |
AU (2) | AU762125B2 (pt) |
BR (1) | BR9907882A (pt) |
CA (1) | CA2319713C (pt) |
DE (1) | DE69932154T2 (pt) |
EA (1) | EA004705B1 (pt) |
ES (1) | ES2272054T3 (pt) |
ID (1) | ID27290A (pt) |
MY (1) | MY122185A (pt) |
TR (1) | TR200002323T2 (pt) |
TW (1) | TWI222867B (pt) |
WO (1) | WO1999040916A1 (pt) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030100532A1 (en) | 1997-02-14 | 2003-05-29 | Gary S. Jacob | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections |
US6689759B1 (en) | 1998-02-12 | 2004-02-10 | G. D. Searle & Co. | Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy |
JP2002502875A (ja) | 1998-02-12 | 2002-01-29 | ジー・ディー・サール・アンド・カンパニー | 肝炎ウイルス感染症を処置するためのn−置換−1,5−ジデオキシ−1,5−イミノ−d−グルシトール化合物の使用 |
CA2362914C (en) | 1999-02-12 | 2009-04-14 | G.D. Searle & Co. | Use of substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds for treating hepatitis virus infections |
AU3858600A (en) * | 1999-02-12 | 2001-02-19 | G.D. Searle & Co. | Glucamine compounds for treating hepatitis virus infections |
ES2302697T3 (es) | 1999-08-10 | 2008-08-01 | The Chancellor, Masters And Scholars Of The University Of Oxford | Compuestos n-alquilicos de cadena larga y derivados oxa de los mismos y uso como composiciones antivirales. |
AU2001236938A1 (en) * | 2000-02-14 | 2001-08-27 | Pharmacia Corporation | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds for treating hepatitis virus infections |
AU2013203974B2 (en) * | 2000-05-23 | 2016-06-02 | Idenix Pharmaceuticals, Inc. | Methods and compositions for treating hepatitis C virus |
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WO2003037265A2 (en) * | 2001-10-30 | 2003-05-08 | Thomas Jefferson University | Method of treating viral infections |
KR20070053229A (ko) * | 2004-08-13 | 2007-05-23 | 미게닉스 인코포레이티드 | 헤파드나비리대 감염을 치료 또는 예방하기 위한 조성물 및방법 |
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WO2008088581A2 (en) * | 2006-08-02 | 2008-07-24 | United Therapeutics Corporation | Liposome treatment of viral infections |
US8097728B2 (en) * | 2007-04-30 | 2012-01-17 | Philadelphia Health & Education Corporation | Iminosugar compounds with antiflavirus activity |
WO2009118658A2 (en) * | 2008-03-26 | 2009-10-01 | University Of Oxford | Endoplasmic reticulum targeting liposomes |
KR20120042716A (ko) | 2009-02-23 | 2012-05-03 | 유나이티드 세러퓨틱스 코오포레이션 | 이미노슈가 및 바이러스성 질환을 치료하는 방법 |
CA2757026A1 (en) * | 2009-03-27 | 2010-09-30 | The Chancellor, Masters And Scholars Of The University Of Oxford | Cholesterol level lowering liposomes |
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CN102625801B (zh) * | 2009-09-04 | 2015-09-09 | 联合治疗公司 | 治疗痘病毒感染的方法 |
IN2014MN02539A (pt) | 2012-06-06 | 2015-07-24 | Unither Virology Llc | |
US10428022B2 (en) | 2014-11-05 | 2019-10-01 | Emergent Virology Llc | Iminosugars useful for the treatment of viral diseases |
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-
1999
- 1999-02-12 JP JP2000531168A patent/JP2002502875A/ja active Pending
- 1999-02-12 BR BR9907882-1A patent/BR9907882A/pt not_active Application Discontinuation
- 1999-02-12 MY MYPI99000516A patent/MY122185A/en unknown
- 1999-02-12 EA EA200000836A patent/EA004705B1/ru not_active IP Right Cessation
- 1999-02-12 US US09/249,220 patent/US6809083B1/en not_active Expired - Lifetime
- 1999-02-12 CA CA2319713A patent/CA2319713C/en not_active Expired - Fee Related
- 1999-02-12 DE DE69932154T patent/DE69932154T2/de not_active Expired - Lifetime
- 1999-02-12 WO PCT/US1999/001874 patent/WO1999040916A1/en active IP Right Grant
- 1999-02-12 EP EP99908079A patent/EP1061922B9/en not_active Expired - Lifetime
- 1999-02-12 AU AU27595/99A patent/AU762125B2/en not_active Ceased
- 1999-02-12 ID IDW20001493A patent/ID27290A/id unknown
- 1999-02-12 KR KR1020007008852A patent/KR20010040937A/ko not_active Application Discontinuation
- 1999-02-12 AT AT99908079T patent/ATE331515T1/de not_active IP Right Cessation
- 1999-02-12 ES ES99908079T patent/ES2272054T3/es not_active Expired - Lifetime
- 1999-02-12 TR TR2000/02323T patent/TR200002323T2/xx unknown
- 1999-04-07 TW TW088102296A patent/TWI222867B/zh not_active IP Right Cessation
-
2003
- 2003-09-18 AU AU2003248024A patent/AU2003248024A1/en not_active Abandoned
-
2004
- 2004-08-03 US US10/910,197 patent/US20050267153A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ES2272054T3 (es) | 2007-04-16 |
US20050267153A1 (en) | 2005-12-01 |
CA2319713C (en) | 2012-06-26 |
ID27290A (id) | 2001-03-22 |
EA004705B1 (ru) | 2004-06-24 |
AU762125B2 (en) | 2003-06-19 |
US6809083B1 (en) | 2004-10-26 |
WO1999040916A1 (en) | 1999-08-19 |
EP1061922B1 (en) | 2006-06-28 |
EP1061922B9 (en) | 2007-03-07 |
JP2002502875A (ja) | 2002-01-29 |
EP1061922A1 (en) | 2000-12-27 |
ATE331515T1 (de) | 2006-07-15 |
TWI222867B (en) | 2004-11-01 |
KR20010040937A (ko) | 2001-05-15 |
TR200002323T2 (tr) | 2000-12-21 |
AU2003248024A1 (en) | 2003-10-30 |
CA2319713A1 (en) | 1999-08-19 |
AU2759599A (en) | 1999-08-30 |
DE69932154T2 (de) | 2007-05-31 |
DE69932154D1 (de) | 2006-08-10 |
EA200000836A1 (ru) | 2001-04-23 |
MY122185A (en) | 2006-03-31 |
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