ES2095032T3 - Derivados 2- y 3-amino y azido de 1,5-iminoazucares como compuestos antivirales. - Google Patents

Derivados 2- y 3-amino y azido de 1,5-iminoazucares como compuestos antivirales.

Info

Publication number
ES2095032T3
ES2095032T3 ES93870061T ES93870061T ES2095032T3 ES 2095032 T3 ES2095032 T3 ES 2095032T3 ES 93870061 T ES93870061 T ES 93870061T ES 93870061 T ES93870061 T ES 93870061T ES 2095032 T3 ES2095032 T3 ES 2095032T3
Authority
ES
Spain
Prior art keywords
derivatives
amino
azido
iminoazucares
antiviral compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93870061T
Other languages
English (en)
Inventor
Ish Kumar Khanna
Richard August Mueller
Richard Mathias Weier
Michael Allan Stealey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/861,696 external-priority patent/US5206251A/en
Priority claimed from US07/861,686 external-priority patent/US5216168A/en
Application filed by GD Searle LLC filed Critical GD Searle LLC
Application granted granted Critical
Publication of ES2095032T3 publication Critical patent/ES2095032T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/42—Oxygen atoms attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

SE DESCRIBEN NUEVOS DERIVADOS DE 1 UE TIENEN SUBSTITUYENTES DE AMINO O ACIDO EN C ESTOS COMPUESTOS SON UTILES INHIBIDORES DE LENTIVIRUS. TAMBIEN SE DESCRIBEN METODOS DE SINTESIS QUIMICA DE ESTOS DERIVADOS E INTERMEDIOS DE CONFORMIDAD CON ESTO.
ES93870061T 1992-04-01 1993-03-31 Derivados 2- y 3-amino y azido de 1,5-iminoazucares como compuestos antivirales. Expired - Lifetime ES2095032T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/861,696 US5206251A (en) 1992-04-01 1992-04-01 2- and 3- amino and azido derivatives of 1,5-iminosugars
US07/861,686 US5216168A (en) 1992-04-01 1992-04-01 2- and 3- amino and azido derivatives of 1,5-iminosugars

Publications (1)

Publication Number Publication Date
ES2095032T3 true ES2095032T3 (es) 1997-02-01

Family

ID=27127639

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93870061T Expired - Lifetime ES2095032T3 (es) 1992-04-01 1993-03-31 Derivados 2- y 3-amino y azido de 1,5-iminoazucares como compuestos antivirales.

Country Status (6)

Country Link
EP (1) EP0566557B1 (es)
AT (1) ATE142201T1 (es)
DE (1) DE69304393T2 (es)
DK (1) DK0566557T3 (es)
ES (1) ES2095032T3 (es)
GR (1) GR3021738T3 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5413999A (en) * 1991-11-08 1995-05-09 Merck & Co., Inc. HIV protease inhibitors useful for the treatment of AIDS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2020278B (en) * 1978-05-03 1983-02-23 Nippon Shinyaku Co Ltd Moranoline dervitives
US4849430A (en) * 1988-03-09 1989-07-18 Monsanto Company Method of inhibiting virus
US5003072A (en) * 1988-11-03 1991-03-26 G. D. Searle & Co. 1,5-dideoxy-1,5-imino-D-glucitol derivatives
EP0410953B1 (en) * 1989-07-27 1995-11-08 Monsanto Company Piperidine compounds with glycosidase inhibition activity
GB8924292D0 (en) * 1989-10-27 1989-12-13 Novalal Ltd The production of a novel dimer chemical product"novo dimers"by the polymersation of indolizidine alkaloids using cyclo dextrin glucosyl transferase

Also Published As

Publication number Publication date
DE69304393D1 (de) 1996-10-10
EP0566557B1 (en) 1996-09-04
EP0566557A1 (en) 1993-10-20
DK0566557T3 (da) 1996-11-04
ATE142201T1 (de) 1996-09-15
GR3021738T3 (en) 1997-02-28
DE69304393T2 (de) 1997-03-20

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