DE69304393D1 - 2- und 3-Amino und Azidoderivate von 1,5-Iminozuckern als antivirale Arzneimittel - Google Patents

2- und 3-Amino und Azidoderivate von 1,5-Iminozuckern als antivirale Arzneimittel

Info

Publication number
DE69304393D1
DE69304393D1 DE69304393T DE69304393T DE69304393D1 DE 69304393 D1 DE69304393 D1 DE 69304393D1 DE 69304393 T DE69304393 T DE 69304393T DE 69304393 T DE69304393 T DE 69304393T DE 69304393 D1 DE69304393 D1 DE 69304393D1
Authority
DE
Germany
Prior art keywords
amino
antiviral drugs
imino sugars
azido derivatives
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69304393T
Other languages
English (en)
Other versions
DE69304393T2 (de
Inventor
Ish Kumar Khanna
Richard August Mueller
Richard Mathias Weier
Michael Allan Stealey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/861,696 external-priority patent/US5206251A/en
Priority claimed from US07/861,686 external-priority patent/US5216168A/en
Application filed by GD Searle LLC filed Critical GD Searle LLC
Application granted granted Critical
Publication of DE69304393D1 publication Critical patent/DE69304393D1/de
Publication of DE69304393T2 publication Critical patent/DE69304393T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/42—Oxygen atoms attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69304393T 1992-04-01 1993-03-31 2- und 3-Amino und Azidoderivate von 1,5-Iminozuckern als antivirale Arzneimittel Expired - Fee Related DE69304393T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/861,696 US5206251A (en) 1992-04-01 1992-04-01 2- and 3- amino and azido derivatives of 1,5-iminosugars
US07/861,686 US5216168A (en) 1992-04-01 1992-04-01 2- and 3- amino and azido derivatives of 1,5-iminosugars

Publications (2)

Publication Number Publication Date
DE69304393D1 true DE69304393D1 (de) 1996-10-10
DE69304393T2 DE69304393T2 (de) 1997-03-20

Family

ID=27127639

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69304393T Expired - Fee Related DE69304393T2 (de) 1992-04-01 1993-03-31 2- und 3-Amino und Azidoderivate von 1,5-Iminozuckern als antivirale Arzneimittel

Country Status (6)

Country Link
EP (1) EP0566557B1 (de)
AT (1) ATE142201T1 (de)
DE (1) DE69304393T2 (de)
DK (1) DK0566557T3 (de)
ES (1) ES2095032T3 (de)
GR (1) GR3021738T3 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5413999A (en) * 1991-11-08 1995-05-09 Merck & Co., Inc. HIV protease inhibitors useful for the treatment of AIDS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2020278B (en) * 1978-05-03 1983-02-23 Nippon Shinyaku Co Ltd Moranoline dervitives
US4849430A (en) * 1988-03-09 1989-07-18 Monsanto Company Method of inhibiting virus
US5003072A (en) * 1988-11-03 1991-03-26 G. D. Searle & Co. 1,5-dideoxy-1,5-imino-D-glucitol derivatives
EP0410953B1 (de) * 1989-07-27 1995-11-08 Monsanto Company Glykosidasehemmende Piperidinverbindungen
GB8924292D0 (en) * 1989-10-27 1989-12-13 Novalal Ltd The production of a novel dimer chemical product"novo dimers"by the polymersation of indolizidine alkaloids using cyclo dextrin glucosyl transferase

Also Published As

Publication number Publication date
ATE142201T1 (de) 1996-09-15
EP0566557A1 (de) 1993-10-20
ES2095032T3 (es) 1997-02-01
DK0566557T3 (da) 1996-11-04
DE69304393T2 (de) 1997-03-20
GR3021738T3 (en) 1997-02-28
EP0566557B1 (de) 1996-09-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee