SE8402551D0 - Cinnamoylmoranolin-derivat - Google Patents

Cinnamoylmoranolin-derivat

Info

Publication number
SE8402551D0
SE8402551D0 SE8402551A SE8402551A SE8402551D0 SE 8402551 D0 SE8402551 D0 SE 8402551D0 SE 8402551 A SE8402551 A SE 8402551A SE 8402551 A SE8402551 A SE 8402551A SE 8402551 D0 SE8402551 D0 SE 8402551D0
Authority
SE
Sweden
Prior art keywords
cinnamoylmoranolin
derivatives
same
aralkylmoranoline
aralkenylmoranoline
Prior art date
Application number
SE8402551A
Other languages
English (en)
Other versions
SE8402551L (sv
SE451017B (sv
Inventor
S Matsumura
H Enomoto
Y Aoyagi
Y Yoshikuni
K Kura
M Yagi
I Shirahase
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP53053603A external-priority patent/JPS5943947B2/ja
Priority claimed from JP8260678A external-priority patent/JPS5943948B2/ja
Priority claimed from JP12066178A external-priority patent/JPS5943949B2/ja
Priority claimed from JP571479A external-priority patent/JPS6026387B2/ja
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of SE8402551L publication Critical patent/SE8402551L/sv
Publication of SE8402551D0 publication Critical patent/SE8402551D0/sv
Publication of SE451017B publication Critical patent/SE451017B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE8402551A 1978-05-03 1984-05-11 Cinnamylmoranolin-derivat SE451017B (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP53053603A JPS5943947B2 (ja) 1978-05-03 1978-05-03 Ｎ−置換モラノリン誘導体
JP8260678A JPS5943948B2 (ja) 1978-07-06 1978-07-06 置換モラノリン誘導体
JP12066178A JPS5943949B2 (ja) 1978-09-29 1978-09-29 モラノリンのｎ−置換誘導体
JP571479A JPS6026387B2 (ja) 1979-01-20 1979-01-20 シンナミルモラノリン誘導体

Publications (3)

Publication Number Publication Date
SE8402551L SE8402551L (sv) 1984-05-11
SE8402551D0 true SE8402551D0 (sv) 1984-05-11
SE451017B SE451017B (sv) 1987-08-24

Family

ID=27454348

Family Applications (4)

Application Number Title Priority Date Filing Date
SE7903817A SE436874B (sv) 1978-05-03 1979-05-02 N-substituerade moranolinderivat
SE8402550A SE451016B (sv) 1978-05-03 1984-05-11 N-substituerade derivat av moranolin
SE8402551A SE451017B (sv) 1978-05-03 1984-05-11 Cinnamylmoranolin-derivat
SE8402549A SE451015B (sv) 1978-05-03 1984-05-11 Substituerade moranolinderivat

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SE7903817A SE436874B (sv) 1978-05-03 1979-05-02 N-substituerade moranolinderivat
SE8402550A SE451016B (sv) 1978-05-03 1984-05-11 N-substituerade derivat av moranolin

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE8402549A SE451015B (sv) 1978-05-03 1984-05-11 Substituerade moranolinderivat

Country Status (9)

Country Link
US (1) US4533668A (sv)
CH (1) CH642629A5 (sv)
DE (1) DE2915037C3 (sv)
DK (1) DK151623C (sv)
FR (1) FR2424910A1 (sv)
GB (1) GB2020278B (sv)
IT (1) IT1116820B (sv)
NL (1) NL175820C (sv)
SE (4) SE436874B (sv)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO154918C (no) * 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
DE2925943A1 (de) * 1979-06-27 1981-01-29 Bayer Ag 1-alkadien-2,4-yl-2-hydroxymethyl3,4,5-trihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE2942365A1 (de) * 1979-10-19 1981-05-14 Bayer Ag, 5090 Leverkusen 2-hydroxyalkyl-3,4,5-trihydroxy-(pi)-peridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3007078A1 (de) * 1980-02-26 1981-09-10 Bayer Ag, 5090 Leverkusen Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel sowie in der tierernaehrung
JP2504000B2 (ja) * 1986-09-02 1996-06-05 日本新薬株式会社 グルコシルモラノリン誘導体
JPS6461459A (en) * 1987-08-28 1989-03-08 Nippon Shinyaku Co Ltd Moranoline derivative
GB8827701D0 (en) * 1987-12-09 1988-12-29 Nippon Shinyaku Co Ltd Thrombolytic &c compositions
US5192772A (en) * 1987-12-09 1993-03-09 Nippon Shinyaku Co. Ltd. Therapeutic agents
US4985445A (en) * 1988-02-12 1991-01-15 Meiji Seika Kaisha, Ltd. Cancer cell metastasis inhibitors and novel compounds
EP0350012A3 (en) * 1988-07-08 1990-09-05 Meiji Seika Kaisha Ltd. Antiviral composition
US5342951A (en) * 1992-04-01 1994-08-30 G.D. Searle & Co. 2- and 3-sulfur derivatives of 1,5-iminosugars
US5331096A (en) * 1992-04-01 1994-07-19 G. D. Searle & Co. 2- and 3-sulfur derivatives of 1,5-iminosugars
US5258518A (en) * 1992-04-01 1993-11-02 G. D. Searle & Co. 2-substituted tertiary carbinol derivatives of deoxynojirimycin
US5216168A (en) * 1992-04-01 1993-06-01 G. D. Searle & Co. 2- and 3- amino and azido derivatives of 1,5-iminosugars
ATE142201T1 (de) * 1992-04-01 1996-09-15 Searle & Co 2- und 3-amino und azidoderivate von 1,5- iminozuckern als antivirale arzneimittel
US5206251A (en) * 1992-04-01 1993-04-27 G. D. Searle & Co. 2- and 3- amino and azido derivatives of 1,5-iminosugars
US5268482A (en) * 1992-04-01 1993-12-07 G. D. Searle & Co. 2- and 3-sulfur derivatives of 1,5-iminosugars
US5798366A (en) * 1993-05-13 1998-08-25 Monsanto Company Method for treatment of CNS-involved lysosomal storage diseases
US5399567A (en) * 1993-05-13 1995-03-21 Monsanto Company Method of treating cholera
US6291657B1 (en) * 1993-05-13 2001-09-18 Monsanto Company Deoxygalactonojirimycin derivatives
US20030100532A1 (en) * 1997-02-14 2003-05-29 Gary S. Jacob Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections
EP1030839B1 (en) 1997-11-10 2004-02-04 G.D. SEARLE & CO. Use of alkylated iminosugars to treat multidrug resistance
KR20010040937A (ko) 1998-02-12 2001-05-15 윌리암스 로저 에이 간염 바이러스 감염의 치료를 위한 ｎ-치환된1,5-디데옥시-1,5-이미노-ｄ-글루시톨 화합물의 용도
US6689759B1 (en) 1998-02-12 2004-02-10 G. D. Searle & Co. Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy
EP1173161A2 (en) 1999-02-12 2002-01-23 G.D. SEARLE & CO. Glucamine compounds for treating hepatitis virus infections
US6545021B1 (en) 1999-02-12 2003-04-08 G.D. Searle & Co. Use of substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds for treating hepatitis virus infections
WO2001060366A1 (en) * 2000-02-14 2001-08-23 Pharmacia Corporation Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds for treating hepatitis virus infections
JP2008519840A (ja) * 2004-11-10 2008-06-12 ジェンザイム・コーポレイション 糖尿病の処置方法
AT502145B1 (de) * 2005-03-24 2012-01-15 Univ Graz Tech Glycosidase-hemmendes iminoalditol
PL2032134T3 (pl) 2006-05-09 2015-11-30 Genzyme Corp Sposoby leczenia stłuszczeniowej choroby wątroby obejmujące hamowanie syntezy glikosfingolipidów
JP5241709B2 (ja) * 2006-05-24 2013-07-17 ユナイテッド セラピューティクス コーポレーション デオキシノジリマイシンおよびｄ−アラビニトールのアナログおよび使用方法
US8097728B2 (en) * 2007-04-30 2012-01-17 Philadelphia Health & Education Corporation Iminosugar compounds with antiflavirus activity
EP2594564B1 (en) * 2007-05-31 2016-09-28 Genzyme Corporation 2-acylaminopropanol-type glucosylceramide synthase inhibitors
RU2517345C9 (ru) 2007-10-05 2014-08-20 Гензим Корпорейшн Способ лечения поликистозных заболеваний почек с помощью производных церамида
CA2731685A1 (en) 2008-07-28 2010-02-04 Genzyme Corporation Glucosylceramide synthase inhibition for the treatment of collapsing glomerulopathy and other glomerular disease
KR101687039B1 (ko) 2008-10-03 2016-12-15 젠자임 코포레이션 2-아실아미노프로판올형 글루코실세라미드 합성효소 억제제
BR112018072298A2 (pt) 2016-05-02 2019-02-12 Florida State University Research Foundation, Inc. tratamento de infecções pelo vírus da zika usando inibidores da alfa-glicosidase
WO2021168483A2 (en) 2020-02-21 2021-08-26 Florida State University Research Foundation, Inc. Treatment of human coronavirus infections using alpha-glucosidase glycoprotein processing inhibitors
CN115867534A (zh) * 2020-05-07 2023-03-28 阿勒克图治疗公司 非溶酶体葡糖神经酰胺酶抑制剂及其用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5282710A (en) * 1975-12-29 1977-07-11 Nippon Shinyaku Co Ltd Extraction of effective drug component from mulberry
DE2735316C3 (de) * 1977-08-05 1981-01-29 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von nadeiförmigen, ferrimagnetischen Eisenoxiden

Also Published As

Publication number Publication date
CH642629A5 (de) 1984-04-30
NL175820C (nl) 1985-01-02
SE7903817L (sv) 1979-11-04
DE2915037C3 (de) 1981-11-05
SE8402551L (sv) 1984-05-11
SE8402550D0 (sv) 1984-05-11
SE451016B (sv) 1987-08-24
DE2915037A1 (de) 1979-11-08
DK151623C (da) 1988-07-18
SE8402549D0 (sv) 1984-05-11
SE8402549L (sv) 1984-05-11
DK151623B (da) 1987-12-21
DK178379A (da) 1979-11-04
US4533668A (en) 1985-08-06
DE2915037B2 (de) 1981-01-29
FR2424910A1 (fr) 1979-11-30
IT1116820B (it) 1986-02-10
GB2020278A (en) 1979-11-14
FR2424910B1 (sv) 1981-12-11
SE436874B (sv) 1985-01-28
GB2020278B (en) 1983-02-23
SE451015B (sv) 1987-08-24
SE8402550L (sv) 1984-05-11
NL175820B (nl) 1984-08-01
NL7903421A (nl) 1979-11-06
IT7948904A0 (it) 1979-05-02
SE451017B (sv) 1987-08-24

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