ES472528A1 - Procedimiento para la preparacion de derivados de benzosul- fonamida - Google Patents

Procedimiento para la preparacion de derivados de benzosul- fonamida

Info

Publication number
ES472528A1
ES472528A1 ES472528A ES472528A ES472528A1 ES 472528 A1 ES472528 A1 ES 472528A1 ES 472528 A ES472528 A ES 472528A ES 472528 A ES472528 A ES 472528A ES 472528 A1 ES472528 A1 ES 472528A1
Authority
ES
Spain
Prior art keywords
benzenesulfonamide
derivatives
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES472528A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES472528A1 publication Critical patent/ES472528A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/58—One oxygen atom, e.g. butenolide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Derivados de benzosulfonamida de la fórmula general I: **(Fórmula)** en la que R1 significa hidrógeno, alcohilo o alquenilo con 1 a 4 átomos de carbono, pudiendo el radical alcohilo también llevar un grupo metoxi, significa cicloalcohilo con 3 a 5 miembros en el anillo, bencilo, R2 a R6 significan hidrógeno o un radical alcohilo con 1 a 4 átomos de carbono, R7 significa hidrógeno, alcohilo con 1 a 10 átomos de carbono, pudiendo el radical alcohilo también llevar uno o dos grupos metoxi u otoxi o un grupo etilendioxi o propilendioxi, alquenilo con 3 a 5 átomos de carbono, cicloalcohilo con 3 a 12 miembros en el anillo eventualmente sustituido con un grupo metilo, cicloalcohilalcohilo con 5 o 6 miembros en el anillo y con 1 a 2 átomos de carbono en la porción alcohilo, fenilalcohilo con 1 a 2 átomos de carbono en la porción alcohilo, pudiendo estar el radical fenilo sustituido una o dos veces y pudiendo llevar como sustituyentes metilo, metoxi o cloro.
ES472528A 1977-08-18 1978-08-11 Procedimiento para la preparacion de derivados de benzosul- fonamida Expired ES472528A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772737195 DE2737195A1 (de) 1977-08-18 1977-08-18 Benzolsulfonamidderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ES472528A1 true ES472528A1 (es) 1979-10-01

Family

ID=6016681

Family Applications (1)

Application Number Title Priority Date Filing Date
ES472528A Expired ES472528A1 (es) 1977-08-18 1978-08-11 Procedimiento para la preparacion de derivados de benzosul- fonamida

Country Status (15)

Country Link
US (1) US4235918A (es)
EP (1) EP0001051B1 (es)
JP (1) JPS5444662A (es)
AT (1) AT371109B (es)
AU (1) AU519998B2 (es)
CA (1) CA1117951A (es)
DE (2) DE2737195A1 (es)
DK (1) DK363578A (es)
EG (1) EG13496A (es)
ES (1) ES472528A1 (es)
FI (1) FI782500A (es)
HU (1) HU177456B (es)
IL (1) IL55369A (es)
IT (1) IT1098071B (es)
ZA (1) ZA784689B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3323511A1 (de) * 1983-06-30 1985-01-10 Hoechst Ag, 6230 Frankfurt 2-keto-sulfonamide und verfahren zu ihrer herstellung
DE3323510A1 (de) * 1983-06-30 1985-01-10 Hoechst Ag, 6230 Frankfurt 2-ketosulfonamide und verfahren zu deren herstellung
DE3713757A1 (de) * 1987-04-24 1988-11-10 Hoechst Ag Benzolsulfonamidderivate und verfahren zu ihrer herstellung
DE10047110A1 (de) * 2000-09-22 2002-04-18 Bayer Ag Optisch aktive 2,5-Bisaryl-DELTA·1·-Pyrroline

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1361388A (en) * 1970-08-05 1974-07-24 Geistlich Soehne Ag Ny--sulphamoylaryl--pyrrolidines
GB1406882A (en) * 1972-04-28 1975-09-17 Leo Pharm Prod Ltd Benzoic acid derivatives and benzisptjoaup'e 1.1 dopxode derovatoves
FI325174A (es) 1973-11-19 1975-05-20 Sandoz Ag
US3947460A (en) 1974-06-27 1976-03-30 Sandoz, Inc. 5-Hydroxy-5-substituted phenyl-pyrrolidones and piperidinones
US4125614A (en) * 1974-07-27 1978-11-14 Hoechst Aktiengesellschaft Thiazolidine derivatives
DE2436263C2 (de) * 1974-07-27 1983-02-17 Hoechst Ag, 6000 Frankfurt Thiazolidinderivate und Verfahren zu ihrer Herstellung
DE2533821A1 (de) * 1975-07-29 1977-02-17 Hoechst Ag Thiazolidinderivate und verfahren zu ihrer herstellung
DE2546165A1 (de) * 1975-10-15 1977-04-28 Hoechst Ag Thiazolidinderivate und verfahren zu ihrer herstellung
SE7700436L (sv) * 1976-01-17 1977-07-18 Hoechst Ag Tiazolidinderivat och forfarande for deras framstellning
SE7700500L (sv) * 1976-01-20 1977-07-21 Hoechst Ag Tiazolidinderivat och forfarande for deras framstellning
CH628622A5 (de) * 1976-12-24 1982-03-15 Ciba Geigy Ag Verfahren zur herstellung von neuen in 4-stellung substituierten 3-sulfamoylbenzoesaeuren.

Also Published As

Publication number Publication date
DK363578A (da) 1979-02-19
CA1117951A (en) 1982-02-09
HU177456B (en) 1981-10-28
EP0001051B1 (de) 1981-02-11
JPS5444662A (en) 1979-04-09
AU519998B2 (en) 1982-01-07
ATA598578A (de) 1982-10-15
IL55369A (en) 1984-05-31
EG13496A (en) 1981-12-31
IL55369A0 (en) 1978-10-31
DE2860471D1 (en) 1981-03-26
DE2737195A1 (de) 1979-03-01
ZA784689B (en) 1979-08-29
AT371109B (de) 1983-06-10
EP0001051A3 (en) 1979-04-04
AU3900778A (en) 1980-02-21
US4235918A (en) 1980-11-25
FI782500A (fi) 1979-02-19
IT1098071B (it) 1985-08-31
IT7826779A0 (it) 1978-08-16
EP0001051A2 (de) 1979-03-21

Similar Documents

Publication Publication Date Title
DE2861729D1 (en) Aliphatic derivatives of phosphonoformic acid, pharmaceutical compositions and methods for combating virus infections
SE8402550L (sv) N-substituerade deridvat av moranolin
DE2862419D1 (en) Derivatives of 7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid, their preparation, pharmaceutical compositions containing them and intermediates
IL59425A (en) Pharmaceutical compositions comprising n-substituted aziridine-2-carboxylic acid derivatives,certain such compounds and their preparation
HK87285A (en) Mercapto-imidazole derivatives,their preparation,mercapto-imidazole derivatives for the treatment of inflammatory diseases and their pharmaceutical compositions
ES476106A1 (es) Procedimiento para la preparacion de 4-espectinomicilamina.
IL56421A (en) 4-pyridone-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
AU530678B2 (en) Phosphono-hydroxy-acetic acid
IT7829133A0 (it) Derivati del6-ossigenato-3,20-diossopregnano, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
NZ188946A (en) 1,2-benzisoxazoloxyacetic acid derivatives pharmaceutical compositions
ES472528A1 (es) Procedimiento para la preparacion de derivados de benzosul- fonamida
ZA793966B (en) N-substituted aziridine-2-carboxylic acid derivatives,processes for their preparation,and pharmaceutical compositions thereof
ZA784501B (en) Derivatives of n-substituted-2-aminobenzoic acid,processesfor their preparation and pharmaceutical compositions thereof
DE3067784D1 (en) 2-hydroxyoxanilic acid derivatives and salts, their preparation and pharmaceutical compositions containing them
ZA793720B (en) Substituted 2-phenylamino-imidazoline-(2)derivatives,acid addition salts thereof,processes for their preparation,and pharmaceutical compositions thereof
IL56461A0 (en) 1-naphthyl-acetic acid derivatives, their preparation and pharmaceutical compositions containing them
IT8024152A0 (it) Derivati dell'1,1,2-trifenilpropano e dell'1,1,2-trifenilpropene, procedimento per la loro preparazione e composizioni farmaceutiche contenenti i composti
IT7823470A0 (it) Derivati dell'idrossi-4tiazolidintione-2, loro preparazione e composizioni che licontengono.
IL57735A (en) 7beta-aminothiazolyl-acetamido-3-cephem-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL55253A (en) Benzimidazole-2-methanol and benzimidazole-2-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL55229A0 (en) New oxanilic acid derivatives,their preparation and pharmaceutical compositions containing them
IL57218A (en) 9-deoxy-daunorubicin,9-deoxydoxorubicin,their acid addition salts,preparation thereof and pharmaceutical compositions comprising them
JPS5233662A (en) Preparation of n2-naphthalenesulfonyl-alginamides and acid addition sa lts thereof
IL49066A (en) 7-thienylacetamido or tetrazolylacetamido-3-tetrazolyl-thiomethyl-3-cephem-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions comprising them
ATE9700T1 (de) (n-phosphonoacetyl-l-aspartato) (1,2diaminocyclohexan)-platin (ii) und natrium-, kalium- oder lithiumsalze, ihre herstellung und pharmazeutische zusammensetzungen, die sie enthalten.

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000601