IL55369A - 3-substituted sulphamoyl phenyl-5-hydroxy-2-oxopyrrolidines and their tautomers,their preparation and pharmaceutical compositions - Google Patents
3-substituted sulphamoyl phenyl-5-hydroxy-2-oxopyrrolidines and their tautomers,their preparation and pharmaceutical compositionsInfo
- Publication number
- IL55369A IL55369A IL55369A IL5536978A IL55369A IL 55369 A IL55369 A IL 55369A IL 55369 A IL55369 A IL 55369A IL 5536978 A IL5536978 A IL 5536978A IL 55369 A IL55369 A IL 55369A
- Authority
- IL
- Israel
- Prior art keywords
- oxopyrrolidines
- tautomers
- hydroxy
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/58—One oxygen atom, e.g. butenolide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19772737195 DE2737195A1 (de) | 1977-08-18 | 1977-08-18 | Benzolsulfonamidderivate und verfahren zu ihrer herstellung |
Publications (2)
Publication Number | Publication Date |
---|---|
IL55369A0 IL55369A0 (en) | 1978-10-31 |
IL55369A true IL55369A (en) | 1984-05-31 |
Family
ID=6016681
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL55369A IL55369A (en) | 1977-08-18 | 1978-08-16 | 3-substituted sulphamoyl phenyl-5-hydroxy-2-oxopyrrolidines and their tautomers,their preparation and pharmaceutical compositions |
Country Status (15)
Country | Link |
---|---|
US (1) | US4235918A (xx) |
EP (1) | EP0001051B1 (xx) |
JP (1) | JPS5444662A (xx) |
AT (1) | AT371109B (xx) |
AU (1) | AU519998B2 (xx) |
CA (1) | CA1117951A (xx) |
DE (2) | DE2737195A1 (xx) |
DK (1) | DK363578A (xx) |
EG (1) | EG13496A (xx) |
ES (1) | ES472528A1 (xx) |
FI (1) | FI782500A (xx) |
HU (1) | HU177456B (xx) |
IL (1) | IL55369A (xx) |
IT (1) | IT1098071B (xx) |
ZA (1) | ZA784689B (xx) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3323510A1 (de) * | 1983-06-30 | 1985-01-10 | Hoechst Ag, 6230 Frankfurt | 2-ketosulfonamide und verfahren zu deren herstellung |
DE3323511A1 (de) * | 1983-06-30 | 1985-01-10 | Hoechst Ag, 6230 Frankfurt | 2-keto-sulfonamide und verfahren zu ihrer herstellung |
DE3713757A1 (de) * | 1987-04-24 | 1988-11-10 | Hoechst Ag | Benzolsulfonamidderivate und verfahren zu ihrer herstellung |
DE10047110A1 (de) * | 2000-09-22 | 2002-04-18 | Bayer Ag | Optisch aktive 2,5-Bisaryl-DELTA·1·-Pyrroline |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1361388A (en) * | 1970-08-05 | 1974-07-24 | Geistlich Soehne Ag | Ny--sulphamoylaryl--pyrrolidines |
GB1406882A (en) * | 1972-04-28 | 1975-09-17 | Leo Pharm Prod Ltd | Benzoic acid derivatives and benzisptjoaup'e 1.1 dopxode derovatoves |
FI325174A (xx) | 1973-11-19 | 1975-05-20 | Sandoz Ag | |
US3947460A (en) | 1974-06-27 | 1976-03-30 | Sandoz, Inc. | 5-Hydroxy-5-substituted phenyl-pyrrolidones and piperidinones |
DE2436263C2 (de) * | 1974-07-27 | 1983-02-17 | Hoechst Ag, 6000 Frankfurt | Thiazolidinderivate und Verfahren zu ihrer Herstellung |
US4125614A (en) * | 1974-07-27 | 1978-11-14 | Hoechst Aktiengesellschaft | Thiazolidine derivatives |
DE2533821A1 (de) * | 1975-07-29 | 1977-02-17 | Hoechst Ag | Thiazolidinderivate und verfahren zu ihrer herstellung |
DE2546165A1 (de) * | 1975-10-15 | 1977-04-28 | Hoechst Ag | Thiazolidinderivate und verfahren zu ihrer herstellung |
SE7700436L (sv) * | 1976-01-17 | 1977-07-18 | Hoechst Ag | Tiazolidinderivat och forfarande for deras framstellning |
SE7700500L (sv) * | 1976-01-20 | 1977-07-21 | Hoechst Ag | Tiazolidinderivat och forfarande for deras framstellning |
CH628622A5 (de) * | 1976-12-24 | 1982-03-15 | Ciba Geigy Ag | Verfahren zur herstellung von neuen in 4-stellung substituierten 3-sulfamoylbenzoesaeuren. |
-
1977
- 1977-08-18 DE DE19772737195 patent/DE2737195A1/de not_active Withdrawn
-
1978
- 1978-08-07 EP EP78100621A patent/EP0001051B1/de not_active Expired
- 1978-08-07 DE DE7878100621T patent/DE2860471D1/de not_active Expired
- 1978-08-11 ES ES472528A patent/ES472528A1/es not_active Expired
- 1978-08-16 IT IT26779/78A patent/IT1098071B/it active
- 1978-08-16 EG EG512/78A patent/EG13496A/xx active
- 1978-08-16 US US05/934,063 patent/US4235918A/en not_active Expired - Lifetime
- 1978-08-16 IL IL55369A patent/IL55369A/xx unknown
- 1978-08-16 FI FI782500A patent/FI782500A/fi unknown
- 1978-08-17 CA CA000309538A patent/CA1117951A/en not_active Expired
- 1978-08-17 AU AU39007/78A patent/AU519998B2/en not_active Expired
- 1978-08-17 AT AT0598578A patent/AT371109B/de not_active IP Right Cessation
- 1978-08-17 HU HU78HO2095A patent/HU177456B/hu unknown
- 1978-08-17 ZA ZA00784689A patent/ZA784689B/xx unknown
- 1978-08-17 DK DK363578A patent/DK363578A/da not_active Application Discontinuation
- 1978-08-18 JP JP10137278A patent/JPS5444662A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ES472528A1 (es) | 1979-10-01 |
HU177456B (en) | 1981-10-28 |
AT371109B (de) | 1983-06-10 |
AU3900778A (en) | 1980-02-21 |
IT1098071B (it) | 1985-08-31 |
DK363578A (da) | 1979-02-19 |
AU519998B2 (en) | 1982-01-07 |
IT7826779A0 (it) | 1978-08-16 |
FI782500A (fi) | 1979-02-19 |
IL55369A0 (en) | 1978-10-31 |
DE2860471D1 (en) | 1981-03-26 |
EP0001051A3 (en) | 1979-04-04 |
US4235918A (en) | 1980-11-25 |
ATA598578A (de) | 1982-10-15 |
EP0001051B1 (de) | 1981-02-11 |
DE2737195A1 (de) | 1979-03-01 |
CA1117951A (en) | 1982-02-09 |
ZA784689B (en) | 1979-08-29 |
JPS5444662A (en) | 1979-04-09 |
EP0001051A2 (de) | 1979-03-21 |
EG13496A (en) | 1981-12-31 |
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