DE2504252A1 - Heterocyclische verbindungen, verfahren zu deren herstellung und sie enthaltende arzneimittel - Google Patents

Heterocyclische verbindungen, verfahren zu deren herstellung und sie enthaltende arzneimittel

Info

Publication number
DE2504252A1
DE2504252A1 DE19752504252 DE2504252A DE2504252A1 DE 2504252 A1 DE2504252 A1 DE 2504252A1 DE 19752504252 DE19752504252 DE 19752504252 DE 2504252 A DE2504252 A DE 2504252A DE 2504252 A1 DE2504252 A1 DE 2504252A1
Authority
DE
Germany
Prior art keywords
group
het
general formula
salts
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19752504252
Other languages
German (de)
English (en)
Other versions
DE2504252C2 (
Inventor
Peder Bernhard Berntsson
Lars Erik Garberg
Stig Ake Ingemar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hassle AB
Original Assignee
Hassle AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hassle AB filed Critical Hassle AB
Publication of DE2504252A1 publication Critical patent/DE2504252A1/de
Application granted granted Critical
Publication of DE2504252C2 publication Critical patent/DE2504252C2/de
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
DE19752504252 1974-02-18 1975-02-01 Heterocyclische verbindungen, verfahren zu deren herstellung und sie enthaltende arzneimittel Granted DE2504252A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7402101A SE418966B (sv) 1974-02-18 1974-02-18 Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan

Publications (2)

Publication Number Publication Date
DE2504252A1 true DE2504252A1 (de) 1975-08-21
DE2504252C2 DE2504252C2 ( ) 1989-02-02

Family

ID=20320233

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752504252 Granted DE2504252A1 (de) 1974-02-18 1975-02-01 Heterocyclische verbindungen, verfahren zu deren herstellung und sie enthaltende arzneimittel

Country Status (23)

Country Link
JP (1) JPS5924157B2 ( )
AT (1) AT343659B ( )
AU (1) AU499639B2 ( )
BE (1) BE825655A ( )
CA (1) CA1060448A ( )
CH (1) CH616160A5 ( )
CS (1) CS194715B2 ( )
DD (1) DD119422A5 ( )
DE (1) DE2504252A1 ( )
DK (1) DK141122B ( )
FI (1) FI59590C ( )
FR (1) FR2261007B1 ( )
GB (1) GB1500043A ( )
HK (1) HK67080A ( )
HU (1) HU172141B ( )
IE (1) IE40858B1 ( )
LU (1) LU71872A1 ( )
MY (1) MY8100208A ( )
NL (1) NL7501917A ( )
NO (1) NO142401C ( )
SE (1) SE418966B ( )
SU (1) SU795476A3 ( )
ZA (1) ZA75558B ( )

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4182766A (en) * 1977-09-19 1980-01-08 Hoffmann-La Roche Inc. Naphth[2,3-d]imidazoles
EP0054147A1 (de) * 1980-12-16 1982-06-23 BASF Aktiengesellschaft Isatogenderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Fungizide
DE3132613A1 (de) * 1980-08-21 1982-06-24 F. Hoffmann-La Roche & Co. AG, 4002 Basel Imidazolderivate
US4343805A (en) * 1978-12-16 1982-08-10 John Wyeth & Brother Limited Heterocyclic compounds
US4552886A (en) * 1982-06-07 1985-11-12 Eli Lilly And Company Fungicidal pyridylmethyl-amines
WO1987005021A1 (en) * 1986-02-14 1987-08-27 Aktiebolaget Hässle Benzimidazoles and their pharmaceutical use
US4767770A (en) * 1984-06-18 1988-08-30 Eli Lilly And Company Method of inhibiting aromatase
WO2003080607A1 (en) * 2002-03-27 2003-10-02 Altana Pharma Ag Novel alkoxypyridine-derivatives
WO2004076451A1 (en) * 2003-02-25 2004-09-10 Altana Pharma Ag Imidazo[4,5-b]quinoline-derivatives and their use as no-synthase inhibitors
WO2005030768A1 (en) * 2003-10-01 2005-04-07 Altana Pharma Ag Imidazo(4,5-b)pyridine-derivatives as inducible no-synthase inhibitors
WO2005030770A1 (en) * 2003-10-01 2005-04-07 Altana Pharma Ag Imidazopyridine-derivatives as inducible no-synthase inhibitors
WO2005030769A1 (en) * 2003-10-01 2005-04-07 Altana Pharma Ag Imidazopyridine-derivatives as inducible no-synthase inhibitors
WO2005030771A1 (en) * 2003-10-01 2005-04-07 Altana Pharma Ag Imidazopyridine-derivatives as inductible no-synthase inhibitors
WO2005061496A1 (en) * 2003-10-01 2005-07-07 Altana Pharma Ag Aminopyridine-derivatives as inductible no-synthase inhibitors
EP2070923A1 (de) 2007-12-11 2009-06-17 Bayer CropScience AG Insektizide Iminoheterocyclen
EP3318561B1 (en) * 2010-05-26 2021-12-22 Sunovion Pharmaceuticals Inc. Heteroaryl compounds and methods of use thereof

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
JPS5364103A (en) * 1976-09-24 1978-06-08 Hitachi Ltd Waste heat recovery boiler
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
IL66340A (en) * 1981-08-13 1986-08-31 Haessle Ab Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation
DE3216843C2 (de) * 1982-05-05 1986-10-23 Ludwig Heumann & Co GmbH, 8500 Nürnberg 3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
GB8307865D0 (en) * 1983-03-22 1983-04-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives
US4503139A (en) * 1983-05-09 1985-03-05 Polaroid Corporation Photographic products and processes and novel compounds
US4575554A (en) * 1983-12-05 1986-03-11 The Upjohn Company Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
FR2593178B1 (fr) * 1986-01-20 1988-04-29 Esteve Labor Dr Derives de 2-benzimidazolylalkylthio (ou sulfinyle ou sulfonyle) leur preparation et leur application en tant que medicaments.
SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
NZ234564A (en) 1986-11-21 1991-04-26 Haessle Ab 1-substituted benzimidazoles and pharmaceutical compositions
SE8604998D0 (sv) 1986-11-21 1986-11-21 Haessle Ab Novel pharmacological compounds
WO1989005643A1 (en) * 1987-12-18 1989-06-29 Pfizer Inc. Heterocyclic-substituted quinoline-carboxylic acids
JPH021280U ( ) * 1988-06-14 1990-01-08
KR920003928B1 (ko) * 1988-09-20 1992-05-18 히사미쯔세이야꾸 가부시기가이샤 신규의 디벤즈[b,e]옥세핀유도체
EG19302A (en) * 1988-12-22 1994-11-30 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
SE8804629D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
SE8804628D0 (sv) 1988-12-22 1988-12-22 Ab Haessle New compounds
JP2679745B2 (ja) * 1989-06-29 1997-11-19 明治製菓株式会社 アゾール誘導体及びそれらを有効成分とする抗潰瘍剤
JPH0347053U ( ) * 1989-09-16 1991-04-30
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US5049674A (en) 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1804450A1 (de) * 1968-10-21 1970-05-27 Egyt Gyogyszervegyeszeti Gyar Benzazol-Derivate und Verfahren zur Herstellung derselben

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1804450A1 (de) * 1968-10-21 1970-05-27 Egyt Gyogyszervegyeszeti Gyar Benzazol-Derivate und Verfahren zur Herstellung derselben

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4248880A (en) 1977-09-19 1981-02-03 Hoffmann-La Roche Inc. Treatment of gastric ulcers with naphthimidazole derivatives
US4182766A (en) * 1977-09-19 1980-01-08 Hoffmann-La Roche Inc. Naphth[2,3-d]imidazoles
US4343805A (en) * 1978-12-16 1982-08-10 John Wyeth & Brother Limited Heterocyclic compounds
DE3132613A1 (de) * 1980-08-21 1982-06-24 F. Hoffmann-La Roche & Co. AG, 4002 Basel Imidazolderivate
EP0054147A1 (de) * 1980-12-16 1982-06-23 BASF Aktiengesellschaft Isatogenderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Fungizide
US4552886A (en) * 1982-06-07 1985-11-12 Eli Lilly And Company Fungicidal pyridylmethyl-amines
US4767770A (en) * 1984-06-18 1988-08-30 Eli Lilly And Company Method of inhibiting aromatase
WO1987005021A1 (en) * 1986-02-14 1987-08-27 Aktiebolaget Hässle Benzimidazoles and their pharmaceutical use
EP0242341A1 (en) * 1986-02-14 1987-10-21 Aktiebolaget Hässle Benzimidazoles, process for their preparation and preparations containing same
WO2003080607A1 (en) * 2002-03-27 2003-10-02 Altana Pharma Ag Novel alkoxypyridine-derivatives
CN1307176C (zh) * 2002-03-27 2007-03-28 奥坦纳医药公司 新的烷氧基吡啶衍生物
US7138399B2 (en) 2002-03-27 2006-11-21 Altana Pharma Ag Alkoxypyridine-derivatives
WO2004076451A1 (en) * 2003-02-25 2004-09-10 Altana Pharma Ag Imidazo[4,5-b]quinoline-derivatives and their use as no-synthase inhibitors
WO2005030770A1 (en) * 2003-10-01 2005-04-07 Altana Pharma Ag Imidazopyridine-derivatives as inducible no-synthase inhibitors
WO2005030771A1 (en) * 2003-10-01 2005-04-07 Altana Pharma Ag Imidazopyridine-derivatives as inductible no-synthase inhibitors
WO2005061496A1 (en) * 2003-10-01 2005-07-07 Altana Pharma Ag Aminopyridine-derivatives as inductible no-synthase inhibitors
WO2005030769A1 (en) * 2003-10-01 2005-04-07 Altana Pharma Ag Imidazopyridine-derivatives as inducible no-synthase inhibitors
WO2005030768A1 (en) * 2003-10-01 2005-04-07 Altana Pharma Ag Imidazo(4,5-b)pyridine-derivatives as inducible no-synthase inhibitors
EA010261B1 (ru) * 2003-10-01 2008-06-30 Алтана Фарма Аг Производные имидазопиридина как ингибиторы индуцируемой no - синтазы
CN100415746C (zh) * 2003-10-01 2008-09-03 奥坦纳医药公司 氨基吡啶衍生物作为可诱导的no-合酶抑制剂
CN100415745C (zh) * 2003-10-01 2008-09-03 奥坦纳医药公司 作为可诱导的no合成酶抑制剂的咪唑并吡啶衍生物
CN100422182C (zh) * 2003-10-01 2008-10-01 奥坦纳医药公司 作为诱导型no-合酶抑制剂的咪唑并吡啶类衍生物
EP2070923A1 (de) 2007-12-11 2009-06-17 Bayer CropScience AG Insektizide Iminoheterocyclen
EP3318561B1 (en) * 2010-05-26 2021-12-22 Sunovion Pharmaceuticals Inc. Heteroaryl compounds and methods of use thereof

Also Published As

Publication number Publication date
HU172141B (hu) 1978-06-28
FI59590B (fi) 1981-05-29
CS194715B2 (en) 1979-12-31
IE40858B1 (en) 1979-08-29
JPS5924157B2 (ja) 1984-06-07
HK67080A (en) 1980-12-05
DE2504252C2 ( ) 1989-02-02
DK54075A ( ) 1975-10-20
ATA113775A (de) 1977-10-15
GB1500043A (en) 1978-02-08
NL7501917A (nl) 1975-08-20
FR2261007A1 ( ) 1975-09-12
SE418966B (sv) 1981-07-06
FI59590C (fi) 1981-09-10
BE825655A (fr) 1975-08-18
NO142401C (no) 1980-08-13
CH616160A5 (en) 1980-03-14
DK141122C ( ) 1980-07-07
FR2261007B1 ( ) 1978-11-24
AU7820675A (en) 1976-08-19
ZA75558B (en) 1976-01-28
AU499639B2 (en) 1979-04-26
JPS50116474A (en) 1975-09-11
LU71872A1 ( ) 1975-12-09
SU795476A3 (ru) 1981-01-07
AT343659B (de) 1978-06-12
FI750421A ( ) 1975-08-19
NO142401B (no) 1980-05-05
DK141122B (da) 1980-01-21
NO750541L ( ) 1975-08-19
DD119422A5 ( ) 1976-04-20
MY8100208A (en) 1981-12-31
IE40858L (en) 1975-08-18
CA1060448A (en) 1979-08-14
SE7402101L ( ) 1975-08-19

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee