SE8604566D0 - Novel compunds - Google Patents

Novel compunds

Info

Publication number
SE8604566D0
SE8604566D0 SE8604566A SE8604566A SE8604566D0 SE 8604566 D0 SE8604566 D0 SE 8604566D0 SE 8604566 A SE8604566 A SE 8604566A SE 8604566 A SE8604566 A SE 8604566A SE 8604566 D0 SE8604566 D0 SE 8604566D0
Authority
SE
Sweden
Prior art keywords
alkyl
represents hydrogen
compounds
aryl
novel
Prior art date
Application number
SE8604566A
Other languages
English (en)
Inventor
C B Briving
S A I Carlsson
P L Lindberg
A H Mattsson
M P Nordberg
B M G Wallmark
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Priority to SE8604566A priority Critical patent/SE8604566D0/sv
Publication of SE8604566D0 publication Critical patent/SE8604566D0/sv
Priority to ZA877400A priority patent/ZA877400B/xx
Priority to NZ222104A priority patent/NZ222104A/xx
Priority to AU79498/87A priority patent/AU7949887A/en
Priority to IE872768A priority patent/IE872768L/xx
Priority to IL84193A priority patent/IL84193A0/xx
Priority to AT87850313T priority patent/ATE86616T1/de
Priority to ES87850313T priority patent/ES2053587T3/es
Priority to EP87850313A priority patent/EP0266326B1/en
Priority to DE8787850313T priority patent/DE3784624T2/de
Priority to DK555387A priority patent/DK555387A/da
Priority to SU874203542A priority patent/SU1597100A3/ru
Priority to DD87308279A priority patent/DD264433A5/de
Priority to NO874454A priority patent/NO874454L/no
Priority to FI874702A priority patent/FI874702A/fi
Priority to JP62268376A priority patent/JP2738932B2/ja
Priority to HU874769A priority patent/HU196971B/hu
Priority to KR870011881A priority patent/KR880005092A/ko
Priority to CN198787107175A priority patent/CN87107175A/zh
Priority to PL1987268455A priority patent/PL268455A1/xx
Priority to PT86008A priority patent/PT86008B/pt
Priority to US07/631,221 priority patent/US5106862A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
SE8604566A 1986-10-27 1986-10-27 Novel compunds SE8604566D0 (sv)

Priority Applications (22)

Application Number Priority Date Filing Date Title
SE8604566A SE8604566D0 (sv) 1986-10-27 1986-10-27 Novel compunds
ZA877400A ZA877400B (en) 1986-10-27 1987-10-01 Novel derivatives of benzimidazoles active as anti-ulcer agents
NZ222104A NZ222104A (en) 1986-10-27 1987-10-09 Benzimidazoles and anti gastric ulcer compositions
AU79498/87A AU7949887A (en) 1986-10-27 1987-10-09 Benzimidazole derivatives
IE872768A IE872768L (en) 1986-10-27 1987-10-14 Novel derivatives of benzimidazoles¹active as anti-ulcer agents
IL84193A IL84193A0 (en) 1986-10-27 1987-10-18 Novel derivatives of benzimidazoles active as anti-ulcer agents
DE8787850313T DE3784624T2 (de) 1986-10-27 1987-10-19 Benzimidazolderivate mit einer wirkung als ulkusmittel.
AT87850313T ATE86616T1 (de) 1986-10-27 1987-10-19 Benzimidazolderivate mit einer wirkung als ulkusmittel.
ES87850313T ES2053587T3 (es) 1986-10-27 1987-10-19 Nuevos derivados de bencimidazoles activos como agentes anti-ulcera.
EP87850313A EP0266326B1 (en) 1986-10-27 1987-10-19 Novel derivatives of benzimidazoles active as anti-ulcer agents
DK555387A DK555387A (da) 1986-10-27 1987-10-23 Benzimidazolderivater
SU874203542A SU1597100A3 (ru) 1986-10-27 1987-10-26 Способ получени производных бензимидазола
KR870011881A KR880005092A (ko) 1986-10-27 1987-10-26 항궤양제로서 유효한 벤즈이미다졸의 신규 유도체
DD87308279A DD264433A5 (de) 1986-10-27 1987-10-26 Verfahren zur herstellung von benzimidazolderivaten
NO874454A NO874454L (no) 1986-10-27 1987-10-26 Nye derivater av benzimidazoler med anti-ulcusaktivitet og fremgangsmaate for deres fremstilling.
FI874702A FI874702A (fi) 1986-10-27 1987-10-26 Foerfarande foer framstaellning av nya benzimidazolderivater.
JP62268376A JP2738932B2 (ja) 1986-10-27 1987-10-26 抗潰瘍剤として活性な新規ベンズイミダゾール誘導体
HU874769A HU196971B (en) 1986-10-27 1987-10-26 Process for producing new benzimidazol derivatives and pharmaceutical compositions containing them
CN198787107175A CN87107175A (zh) 1986-10-27 1987-10-27 作为抗溃疡剂的新苯并咪唑衍生物
PL1987268455A PL268455A1 (en) 1986-10-27 1987-10-27 The method of manufacture of new derivatives of benzimidazole
PT86008A PT86008B (pt) 1986-10-27 1987-10-27 Processo para a preparacao de derivados de benzimidazois com actividade anti-ulcera e de composicoes farmaceuticas que os contem
US07/631,221 US5106862A (en) 1986-10-27 1990-12-12 Derivatives of benzimidazoles active as anti-ulcer agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8604566A SE8604566D0 (sv) 1986-10-27 1986-10-27 Novel compunds

Publications (1)

Publication Number Publication Date
SE8604566D0 true SE8604566D0 (sv) 1986-10-27

Family

ID=20366077

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8604566A SE8604566D0 (sv) 1986-10-27 1986-10-27 Novel compunds

Country Status (22)

Country Link
US (1) US5106862A (sv)
EP (1) EP0266326B1 (sv)
JP (1) JP2738932B2 (sv)
KR (1) KR880005092A (sv)
CN (1) CN87107175A (sv)
AT (1) ATE86616T1 (sv)
AU (1) AU7949887A (sv)
DD (1) DD264433A5 (sv)
DE (1) DE3784624T2 (sv)
DK (1) DK555387A (sv)
ES (1) ES2053587T3 (sv)
FI (1) FI874702A (sv)
HU (1) HU196971B (sv)
IE (1) IE872768L (sv)
IL (1) IL84193A0 (sv)
NO (1) NO874454L (sv)
NZ (1) NZ222104A (sv)
PL (1) PL268455A1 (sv)
PT (1) PT86008B (sv)
SE (1) SE8604566D0 (sv)
SU (1) SU1597100A3 (sv)
ZA (1) ZA877400B (sv)

Families Citing this family (36)

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Publication number Priority date Publication date Assignee Title
US5300519A (en) * 1988-07-06 1994-04-05 The University Of Sheffield Immunosuppressive agents
AU653524B2 (en) * 1990-06-08 1994-10-06 Roussel-Uclaf New imidazole derivatives, their preparation process, the new intermediates obtained, their use as medicaments and the pharmaceutical compositions containing them
WO1996004251A1 (fr) * 1994-08-03 1996-02-15 Fujisawa Pharmaceutical Co., Ltd. Compose heterocyclique
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
SE9602286D0 (sv) * 1996-06-10 1996-06-10 Astra Ab New compounds
KR100487029B1 (ko) * 1996-06-10 2005-11-25 아스트라제네카 악티에볼라그 신규화합물
EP0934307B1 (en) 1996-06-19 2011-04-27 Aventis Pharma Limited Substituted azabicylic compounds and their use as inhibitors of the production of tnf and cyclic amp phosphodiesterase
JP2000516611A (ja) 1996-08-14 2000-12-12 ワーナー―ランバート・コンパニー Ｍｃｐ―１アンタゴニストとしての２―フェニルベンズイミダゾール誘導体
NO312361B1 (no) * 2000-05-12 2002-04-29 Norsk Hydro As Fremgangsmate for fremstilling av hydroksyforbindelser
JP4730574B2 (ja) * 2001-05-18 2011-07-20 山田化学工業株式会社 ベンズイミダゾール化合物、アゾベンズイミダゾール化合物とそのキレート化合物
JP2005521662A (ja) * 2002-01-25 2005-07-21 サンタラス インコーポレイティッド プロトンポンプ阻害剤の経粘膜送達
AR043063A1 (es) * 2002-12-13 2005-07-13 Altana Pharma Ag Bencimidazoles 6-sustituidos y su uso como inhibidores de secreciones gastricas
JP2006518751A (ja) * 2003-02-20 2006-08-17 サンタラス インコーポレイティッド 胃酸の急速かつ持続的な抑制のための新規製剤、オメプラゾール制酸剤複合体−即時放出物
NZ542177A (en) * 2003-04-04 2009-02-28 Altana Pharma Ag Cyclic benzimidazoles for use against gastrointestinal disorders
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
CA2531564C (en) * 2003-07-18 2016-01-19 Santarus, Inc. Pharmaceutical composition for inhibiting acid secretion
US20050031700A1 (en) * 2003-07-18 2005-02-10 Sanatarus, Inc. Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
AR048869A1 (es) * 2004-04-26 2006-06-07 Altana Pharma Ag Bencimidazoles triciclicos
AR049168A1 (es) * 2004-05-18 2006-07-05 Altana Pharma Ag Derivados de benzimidazol
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
JP2008501766A (ja) * 2004-06-09 2008-01-24 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 置換された三環式のベンゾイミダゾール
AR051041A1 (es) * 2004-10-04 2006-12-13 Altana Pharma Ag Bencimidazoles triciclicos condensados
DE602006009105D1 (de) 2005-06-14 2009-10-22 Raqualia Pharma Inc Chroman-substituierte benzimidazolderivate als säurepumpenantagonisten
AR057061A1 (es) * 2005-06-16 2007-11-14 Altana Pharma Ag Espiro-bencimidazoles farmaceuticamente activos y su uso en la fabricacion de medicamentos
CN101341149B (zh) * 2005-12-19 2011-06-08 拉夸里亚创药株式会社 经色原烷取代的苯并咪唑类和它们作为酸泵抑制剂的用途
EP1987028A2 (en) 2006-02-10 2008-11-05 Transtech Pharma, Inc. Benzazole derivatives, compositions, and methods of use as aurora kinase inhibitors
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations
EP2560953B1 (en) * 2010-04-21 2016-01-06 Probiodrug AG Inhibitors of glutaminyl cyclase
JP6002785B2 (ja) * 2012-02-03 2016-10-05 ファイザー・インク ナトリウムチャネルモジュレーターとしてのベンゾイミダゾールおよびイミダゾピリジン誘導体
JP7187449B2 (ja) 2016-09-30 2022-12-12 エピザイム，インコーポレイティド Ｅｈｍｔ２阻害剤としての置換された融合二環式または三環式複素環化合物
JP2020517618A (ja) 2017-04-21 2020-06-18 エピザイム，インコーポレイティド Ｅｈｍｔ２阻害剤との併用療法

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IE31812B1 (en) * 1967-02-03 1973-01-10 Merck & Co Inc Benzimidazole derivatives
FR2260995A1 (en) * 1974-02-14 1975-09-12 Tyortyalian Carlos Benzimidazole-contg. medicaments - for treating non-malignant gastroduodenal disorders, esp. ulcers and hypersecretion
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
DE2737630A1 (de) * 1977-08-20 1979-03-01 Boehringer Mannheim Gmbh Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
SE443977B (sv) * 1977-05-10 1986-03-17 Chinoin Gyogyszer Es Vegyeszet Forfarande for framstellning av 5(6)-tio-bensimidazolderivat
IN148930B (sv) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
US4411517A (en) * 1981-10-23 1983-10-25 Xerox Corporation Very high speed duplicator with document handling
US4492708A (en) * 1982-09-27 1985-01-08 Eli Lilly And Company Antiviral benzimidazoles
JPS5978171A (ja) * 1982-10-26 1984-05-04 Ikeda Mohandou:Kk 複素環式化合物
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
GB8307865D0 (en) * 1983-03-22 1983-04-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives
JPS59188868A (ja) * 1983-04-08 1984-10-26 Matsushita Electric Ind Co Ltd テ−プ引出し装置
JPS60226810A (ja) * 1984-04-25 1985-11-12 Ikeda Mohandou:Kk 抗潰瘍剤
GB8417194D0 (en) * 1984-07-05 1984-08-08 Boots Co Plc Therapeutic agents
CA1341314C (en) * 1984-07-06 2001-11-06 David Cox Derivatives of benzimidazole, benzothiazole and benzoxazole
EP0178413A1 (en) * 1984-08-17 1986-04-23 Beecham Group Plc Benzimidazoles

Also Published As

Publication number Publication date
AU7949887A (en) 1988-04-28
EP0266326A1 (en) 1988-05-04
KR880005092A (ko) 1988-06-28
ZA877400B (en) 1988-04-27
EP0266326B1 (en) 1993-03-10
DE3784624D1 (de) 1993-04-15
IL84193A0 (en) 1988-03-31
DE3784624T2 (de) 1993-06-17
DK555387D0 (da) 1987-10-23
NO874454D0 (no) 1987-10-26
ATE86616T1 (de) 1993-03-15
ES2053587T3 (es) 1994-08-01
HU196971B (en) 1989-02-28
DK555387A (da) 1988-04-28
HUT45236A (en) 1988-06-28
PT86008A (en) 1987-11-01
NO874454L (no) 1988-04-28
JPS63122675A (ja) 1988-05-26
PT86008B (pt) 1990-08-31
US5106862A (en) 1992-04-21
IE872768L (en) 1988-04-27
NZ222104A (en) 1990-07-26
PL268455A1 (en) 1988-09-01
JP2738932B2 (ja) 1998-04-08
FI874702A0 (fi) 1987-10-26
CN87107175A (zh) 1988-05-11
FI874702A (fi) 1988-04-28
SU1597100A3 (ru) 1990-09-30
DD264433A5 (de) 1989-02-01

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