DE2138329A1 - Polysaccharide und Verfahren zu deren Herstellung - Google Patents
Polysaccharide und Verfahren zu deren HerstellungInfo
- Publication number
- DE2138329A1 DE2138329A1 DE19712138329 DE2138329A DE2138329A1 DE 2138329 A1 DE2138329 A1 DE 2138329A1 DE 19712138329 DE19712138329 DE 19712138329 DE 2138329 A DE2138329 A DE 2138329A DE 2138329 A1 DE2138329 A1 DE 2138329A1
- Authority
- DE
- Germany
- Prior art keywords
- ferm
- coriolus
- fomes
- phellinus
- glucan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000004676 glycans Chemical class 0.000 title claims description 10
- 229920001282 polysaccharide Polymers 0.000 title claims description 10
- 239000005017 polysaccharide Substances 0.000 title claims description 10
- 238000000034 method Methods 0.000 title claims description 8
- 238000002360 preparation method Methods 0.000 title description 2
- 229920001503 Glucan Polymers 0.000 claims description 36
- 241000222356 Coriolus Species 0.000 claims description 12
- 241000222640 Polyporus Species 0.000 claims description 10
- 241000221198 Basidiomycota Species 0.000 claims description 8
- 241000123326 Fomes Species 0.000 claims description 8
- 241000123284 Daedalea Species 0.000 claims description 6
- 241000318230 Merulius Species 0.000 claims description 6
- 241000222395 Phlebia Species 0.000 claims description 6
- 241000222354 Trametes Species 0.000 claims description 6
- 241000124020 Heteromorpha Species 0.000 claims description 5
- 241000222344 Irpex lacteus Species 0.000 claims description 5
- 241000123113 Phellinus igniarius Species 0.000 claims description 5
- 235000007685 Pleurotus columbinus Nutrition 0.000 claims description 5
- 240000001462 Pleurotus ostreatus Species 0.000 claims description 5
- 235000001603 Pleurotus ostreatus Nutrition 0.000 claims description 5
- 241000222357 Trametes hirsuta Species 0.000 claims description 5
- 241001480537 Fomitopsis Species 0.000 claims description 4
- 241000747105 Fuscoporia Species 0.000 claims description 4
- 241000123107 Phellinus Species 0.000 claims description 4
- 241000041999 Trametes coccinea Species 0.000 claims description 4
- 241000094558 Antrodia sinuosa Species 0.000 claims description 3
- 241000222455 Boletus Species 0.000 claims description 3
- 241001328224 Boletus cuticularis Species 0.000 claims description 3
- 241000123291 Cryptoporus volvatus Species 0.000 claims description 3
- 241000123276 Daedaleopsis confragosa Species 0.000 claims description 3
- 241001537207 Flammulina Species 0.000 claims description 3
- 241000123330 Fomes fomentarius Species 0.000 claims description 3
- 241000798420 Hornodermoporus latissima Species 0.000 claims description 3
- 241000891199 Hygrocybe flavescens Species 0.000 claims description 3
- 241001175934 Lentinus arcularius Species 0.000 claims description 3
- 241000222635 Lenzites betulinus Species 0.000 claims description 3
- 241000908176 Lepista Species 0.000 claims description 3
- 241001247985 Omphalotus japonicus Species 0.000 claims description 3
- 241000212370 Panus rudis Species 0.000 claims description 3
- 241000115282 Pholiota lubrica Species 0.000 claims description 3
- 241000222582 Phylloporus rhodoxanthus Species 0.000 claims description 3
- 241001236713 Psathyrella candolleana Species 0.000 claims description 3
- 241000222355 Trametes versicolor Species 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 235000015097 nutrients Nutrition 0.000 claims description 3
- 241001236805 Coprinopsis kimurae Species 0.000 claims description 2
- 241001550554 Crucibulum <gastropod> Species 0.000 claims description 2
- 241001487403 Ischnoderma resinosum Species 0.000 claims description 2
- 241000222065 Lycoperdon Species 0.000 claims description 2
- 241000222066 Lycoperdon pyriforme Species 0.000 claims description 2
- 241000222637 Ossicaulis lignatilis Species 0.000 claims description 2
- 241001236904 Pleurocybella Species 0.000 claims description 2
- 208000006268 Sarcoma 180 Diseases 0.000 claims description 2
- 241001631968 Tricholomopsis rutilans Species 0.000 claims description 2
- 230000000694 effects Effects 0.000 claims description 2
- 230000002401 inhibitory effect Effects 0.000 claims description 2
- 241001480588 Macrolepiota Species 0.000 claims 2
- 241000222680 Collybia Species 0.000 claims 1
- 241000123288 Cryptoporus Species 0.000 claims 1
- 241000123294 Daedaleopsis Species 0.000 claims 1
- 241001378514 Favolus Species 0.000 claims 1
- 241000222336 Ganoderma Species 0.000 claims 1
- 241000883306 Huso huso Species 0.000 claims 1
- 241000498300 Hygrocybe Species 0.000 claims 1
- 241000123247 Inonotus Species 0.000 claims 1
- 241000222342 Irpex Species 0.000 claims 1
- 241000995768 Ischnoderma Species 0.000 claims 1
- 241000222418 Lentinus Species 0.000 claims 1
- 241000222634 Lenzites Species 0.000 claims 1
- 241000218554 Lyophyllum Species 0.000 claims 1
- 241001236144 Panaeolus Species 0.000 claims 1
- 241000222638 Panellus Species 0.000 claims 1
- 241000722337 Pholiota Species 0.000 claims 1
- 241000222580 Phylloporus Species 0.000 claims 1
- 241000222350 Pleurotus Species 0.000 claims 1
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims 1
- 241001236760 Psathyrella Species 0.000 claims 1
- 241000222644 Pycnoporus <fungus> Species 0.000 claims 1
- 241000672884 Truncospora Species 0.000 claims 1
- 241001646063 Tyromyces Species 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 208000019585 progressive encephalomyelitis with rigidity and myoclonus Diseases 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 18
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 10
- 239000002609 medium Substances 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 239000001963 growth medium Substances 0.000 description 6
- 230000007062 hydrolysis Effects 0.000 description 6
- 238000006460 hydrolysis reaction Methods 0.000 description 6
- 239000002244 precipitate Substances 0.000 description 6
- 241000699670 Mus sp. Species 0.000 description 5
- 230000005764 inhibitory process Effects 0.000 description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- 244000068988 Glycine max Species 0.000 description 4
- 235000010469 Glycine max Nutrition 0.000 description 4
- 239000008103 glucose Substances 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 3
- 238000000862 absorption spectrum Methods 0.000 description 3
- 229940041514 candida albicans extract Drugs 0.000 description 3
- 238000005119 centrifugation Methods 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 229910052739 hydrogen Inorganic materials 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 235000021039 pomes Nutrition 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000012138 yeast extract Substances 0.000 description 3
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 241000234601 Connopus acervatus Species 0.000 description 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 2
- 241001149422 Ganoderma applanatum Species 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- 244000103635 Lyophyllum ulmarium Species 0.000 description 2
- 235000015934 Lyophyllum ulmarium Nutrition 0.000 description 2
- 241000565604 Macrolepiota procera Species 0.000 description 2
- 241000222639 Panellus stipticus Species 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- 241000672889 Truncospora ochroleuca Species 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 2
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 2
- 235000011130 ammonium sulphate Nutrition 0.000 description 2
- 230000000259 anti-tumor effect Effects 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 238000000921 elemental analysis Methods 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- FGIUAXJPYTZDNR-UHFFFAOYSA-N potassium nitrate Chemical compound [K+].[O-][N+]([O-])=O FGIUAXJPYTZDNR-UHFFFAOYSA-N 0.000 description 2
- VWDWKYIASSYTQR-UHFFFAOYSA-N sodium nitrate Chemical compound [Na+].[O-][N+]([O-])=O VWDWKYIASSYTQR-UHFFFAOYSA-N 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 1
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- PAWQVTBBRAZDMG-UHFFFAOYSA-N 2-(3-bromo-2-fluorophenyl)acetic acid Chemical compound OC(=O)CC1=CC=CC(Br)=C1F PAWQVTBBRAZDMG-UHFFFAOYSA-N 0.000 description 1
- USFZMSVCRYTOJT-UHFFFAOYSA-N Ammonium acetate Chemical compound N.CC(O)=O USFZMSVCRYTOJT-UHFFFAOYSA-N 0.000 description 1
- 239000005695 Ammonium acetate Substances 0.000 description 1
- 239000004254 Ammonium phosphate Substances 0.000 description 1
- 206010003445 Ascites Diseases 0.000 description 1
- 241000228212 Aspergillus Species 0.000 description 1
- 241000222511 Coprinus Species 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- 241001529717 Corticium <basidiomycota> Species 0.000 description 1
- 241001196198 Cyanoboletus pulverulentus Species 0.000 description 1
- 125000002353 D-glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
- 241000039767 Daedalea dickinsii Species 0.000 description 1
- 241000210856 Daedaleopsis purpurea Species 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 101710154757 Exo-beta-1,3-glucanase Proteins 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241000222689 Laetiporus Species 0.000 description 1
- 240000000599 Lentinula edodes Species 0.000 description 1
- 235000001715 Lentinula edodes Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- 241000045365 Microporus <basidiomycete fungus> Species 0.000 description 1
- 241001646100 Oligoporus lacteus Species 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 241000955640 Panaeolus fimicola Species 0.000 description 1
- 239000001888 Peptone Substances 0.000 description 1
- 108010080698 Peptones Proteins 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 241000222480 Schizophyllum Species 0.000 description 1
- 241000576755 Sclerotia Species 0.000 description 1
- 241001558929 Sclerotium <basidiomycota> Species 0.000 description 1
- 241000222646 Stereum Species 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 1
- 241000891150 Trichaptum fuscoviolaceum Species 0.000 description 1
- 239000005862 Whey Substances 0.000 description 1
- 102000007544 Whey Proteins Human genes 0.000 description 1
- 108010046377 Whey Proteins Proteins 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 235000019257 ammonium acetate Nutrition 0.000 description 1
- 229940043376 ammonium acetate Drugs 0.000 description 1
- 235000019270 ammonium chloride Nutrition 0.000 description 1
- 229910000148 ammonium phosphate Inorganic materials 0.000 description 1
- 235000019289 ammonium phosphates Nutrition 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 235000013877 carbamide Nutrition 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 239000003729 cation exchange resin Substances 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- MNNHAPBLZZVQHP-UHFFFAOYSA-N diammonium hydrogen phosphate Chemical compound [NH4+].[NH4+].OP([O-])([O-])=O MNNHAPBLZZVQHP-UHFFFAOYSA-N 0.000 description 1
- AIUDWMLXCFRVDR-UHFFFAOYSA-N dimethyl 2-(3-ethyl-3-methylpentyl)propanedioate Chemical class CCC(C)(CC)CCC(C(=O)OC)C(=O)OC AIUDWMLXCFRVDR-UHFFFAOYSA-N 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000001530 fumaric acid Substances 0.000 description 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
- 210000004013 groin Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007928 intraperitoneal injection Substances 0.000 description 1
- 238000009630 liquid culture Methods 0.000 description 1
- 159000000003 magnesium salts Chemical class 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 235000013379 molasses Nutrition 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- 229940066779 peptones Drugs 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 229920001467 poly(styrenesulfonates) Polymers 0.000 description 1
- 239000004323 potassium nitrate Substances 0.000 description 1
- 235000010333 potassium nitrate Nutrition 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000011218 seed culture Methods 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000004317 sodium nitrate Substances 0.000 description 1
- 235000010344 sodium nitrate Nutrition 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6718970A JPS5339519B1 (enrdf_load_stackoverflow) | 1970-07-31 | 1970-07-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2138329A1 true DE2138329A1 (de) | 1972-02-10 |
Family
ID=13337688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19712138329 Pending DE2138329A1 (de) | 1970-07-31 | 1971-07-30 | Polysaccharide und Verfahren zu deren Herstellung |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JPS5339519B1 (enrdf_load_stackoverflow) |
| DE (1) | DE2138329A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1361382A (enrdf_load_stackoverflow) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2737471A1 (de) * | 1976-08-30 | 1978-03-02 | Kureha Chemical Ind Co Ltd | Verfahren zur zuechtung von basidiomyceten |
| FR2406447A1 (fr) * | 1977-10-24 | 1979-05-18 | Sugiura Mamoru | Substance antitumorale |
| FR2436819A1 (fr) * | 1978-09-21 | 1980-04-18 | Takara Shuzo Co | Polysaccharides anticancereux, leur procede de production et medicament les contenant |
| DE3208057A1 (de) * | 1981-03-06 | 1982-09-16 | Takara Shuzo Co., Ltd., Kyoto | Ss-1,3-glucan mit hohem molekulargewicht und verfahren zu seiner herstellung |
| EP0515216A3 (en) * | 1991-05-24 | 1993-03-31 | Takeda Chemical Industries, Ltd. | Method of purifying beta-1,3-glucans |
| WO1993012243A1 (en) * | 1991-12-16 | 1993-06-24 | Slovenská Technická Univerzita | A new fungal glukan and its preparation |
| EP0614460A4 (en) * | 1991-10-15 | 1995-02-08 | Fmc Corp | Beta-1,3-glucan polysaccharides, compositions, their preparation and uses. |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6673547B2 (ja) * | 2016-04-27 | 2020-03-25 | Smc株式会社 | 流体制御弁 |
| CN110117548B (zh) * | 2019-05-27 | 2022-11-01 | 广东省微生物研究所（广东省微生物分析检测中心） | 一种薄皮纤孔菌新菌株及其人工栽培方法和用途 |
-
1970
- 1970-07-31 JP JP6718970A patent/JPS5339519B1/ja active Pending
-
1971
- 1971-07-28 GB GB3554671A patent/GB1361382A/en not_active Expired
- 1971-07-30 DE DE19712138329 patent/DE2138329A1/de active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2737471A1 (de) * | 1976-08-30 | 1978-03-02 | Kureha Chemical Ind Co Ltd | Verfahren zur zuechtung von basidiomyceten |
| FR2406447A1 (fr) * | 1977-10-24 | 1979-05-18 | Sugiura Mamoru | Substance antitumorale |
| FR2436819A1 (fr) * | 1978-09-21 | 1980-04-18 | Takara Shuzo Co | Polysaccharides anticancereux, leur procede de production et medicament les contenant |
| DE3208057A1 (de) * | 1981-03-06 | 1982-09-16 | Takara Shuzo Co., Ltd., Kyoto | Ss-1,3-glucan mit hohem molekulargewicht und verfahren zu seiner herstellung |
| EP0515216A3 (en) * | 1991-05-24 | 1993-03-31 | Takeda Chemical Industries, Ltd. | Method of purifying beta-1,3-glucans |
| EP0614460A4 (en) * | 1991-10-15 | 1995-02-08 | Fmc Corp | Beta-1,3-glucan polysaccharides, compositions, their preparation and uses. |
| WO1993012243A1 (en) * | 1991-12-16 | 1993-06-24 | Slovenská Technická Univerzita | A new fungal glukan and its preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| GB1361382A (en) | 1974-07-24 |
| JPS5339519B1 (enrdf_load_stackoverflow) | 1978-10-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69514498T2 (de) | Polysaccharide und deren Herstellung | |
| DE3208057C2 (de) | ß-1,3-Glucan | |
| DE2541960A1 (de) | Verfahren zur herstellung von alkohol aus cellulose | |
| DE2138329A1 (de) | Polysaccharide und Verfahren zu deren Herstellung | |
| KR100344755B1 (ko) | 면역력증강물질및그제조방법 | |
| DE2408237A1 (de) | Neue enzymaufbereitung, verfahren zu ihrer herstellung und ihre verwendung | |
| DE2167078C2 (en) | Amylase prepn - for prodn of maltose from starch | |
| CH632639A5 (de) | Verfahren zum zuechten von basidiomyzeten. | |
| DE1915687C2 (de) | Pharmazeutisches Präparat mit Antitumorwirkung | |
| DE69626489T2 (de) | Verfahren zur herstellung bakterieller zellulose | |
| DE2003652C3 (de) | Biotechnisches Verfahren zur Herstellung von CelluJase | |
| DE2041418A1 (de) | Verfahren zur Herstellung von 1,-3,4-Dihydroxyphenylalaninderivaten | |
| DE2223864C3 (de) | Verfahren zur Herstellung von Glucose-Isomerase | |
| DE2318650C2 (de) | Fermentative Herstellung von Deacetylcephalosporin C | |
| DE2336378A1 (de) | Verfahren zur herstellung eines wasserloeslichen polysaccharids | |
| DE2809092A1 (de) | Verfahren zur herstellung von emitanin | |
| DE1442163C (de) | Mikrobiologisches Verfahren zur Herstellung von saurer Protease | |
| DE3617368C2 (de) | Verfahren zur Herstellung eines stickstoffhaltigen Polysaccharids | |
| DE1642637A1 (de) | Milchgerinnungsenzym und Verfahren zu seiner Erzeugung | |
| DE1257148B (de) | Verfahren zur Herstellung von Adenosindiphosphat und -triphosphat | |
| DE1642752C (de) | Verfahren zur Herstellung von L-Prolin | |
| CH648595A5 (de) | Verfahren zur herstellung von polysacchariden mit antikarzinogener aktivitaet. | |
| DE1617586C (de) | Verfahren zur biotechnischen HerT stellung von 6 Azaundm 5 phosphat | |
| DE1792403C (de) | Verfahren zur biotechnischen Herstellung von L Lysin | |
| DE1925952B2 (de) | Mikrobiologisches Verfahren zur Herstellung von L-Asparaginase mit Antitumorwirksamkeit |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OHA | Expiration of time for request for examination |