DE201165T1 - Arzneimittel zur behandlung von emesis, anxietas und "irritable bowel syndrome". - Google Patents

Arzneimittel zur behandlung von emesis, anxietas und "irritable bowel syndrome".

Info

Publication number
DE201165T1
DE201165T1 DE198686301684T DE86301684T DE201165T1 DE 201165 T1 DE201165 T1 DE 201165T1 DE 198686301684 T DE198686301684 T DE 198686301684T DE 86301684 T DE86301684 T DE 86301684T DE 201165 T1 DE201165 T1 DE 201165T1
Authority
DE
Germany
Prior art keywords
formula
alkyl
hydrogen
group
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE198686301684T
Other languages
German (de)
English (en)
Inventor
Gareth John Sawbridgeworth Hertfordshire Cm21 9Bq Sanger
Gordon Sawbridgeworth Hertfordshire Cm21 9Nr Wootton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858506642A external-priority patent/GB8506642D0/en
Priority claimed from GB858509039A external-priority patent/GB8509039D0/en
Priority claimed from GB858531614A external-priority patent/GB8531614D0/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of DE201165T1 publication Critical patent/DE201165T1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Otolaryngology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE198686301684T 1985-03-14 1986-03-10 Arzneimittel zur behandlung von emesis, anxietas und "irritable bowel syndrome". Pending DE201165T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB858506642A GB8506642D0 (en) 1985-03-14 1985-03-14 Compounds
GB858509039A GB8509039D0 (en) 1985-04-09 1985-04-09 Treatment
GB858531614A GB8531614D0 (en) 1985-12-23 1985-12-23 Treatment

Publications (1)

Publication Number Publication Date
DE201165T1 true DE201165T1 (de) 1989-04-20

Family

ID=27262620

Family Applications (4)

Application Number Title Priority Date Filing Date
DE198686301684T Pending DE201165T1 (de) 1985-03-14 1986-03-10 Arzneimittel zur behandlung von emesis, anxietas und "irritable bowel syndrome".
DE199090107640T Pending DE385517T1 (de) 1985-03-14 1986-03-10 Arzneimittel zur behandlung von erbrechen.
DE90107640T Expired - Lifetime DE3688296T2 (de) 1985-03-14 1986-03-10 Arzneimittel zur behandlung von erbrechen.
DE3689974T Expired - Lifetime DE3689974T2 (de) 1985-03-14 1986-03-10 Arzneimittel zur Behandlung von Emesis.

Family Applications After (3)

Application Number Title Priority Date Filing Date
DE199090107640T Pending DE385517T1 (de) 1985-03-14 1986-03-10 Arzneimittel zur behandlung von erbrechen.
DE90107640T Expired - Lifetime DE3688296T2 (de) 1985-03-14 1986-03-10 Arzneimittel zur behandlung von erbrechen.
DE3689974T Expired - Lifetime DE3689974T2 (de) 1985-03-14 1986-03-10 Arzneimittel zur Behandlung von Emesis.

Country Status (7)

Country Link
US (3) US4721720A (https=)
EP (3) EP0201165B1 (https=)
JP (3) JPS61212521A (https=)
CY (1) CY1727A (https=)
DE (4) DE201165T1 (https=)
HK (1) HK77593A (https=)
SG (1) SG61693G (https=)

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DE3689974D1 (de) 1994-08-25
DE3688296T2 (de) 1993-11-04
US4783478A (en) 1988-11-08
EP0201165A2 (en) 1986-11-12
EP0385517B1 (en) 1993-04-14
US4721720A (en) 1988-01-26
EP0201165B1 (en) 1994-07-20
EP0201165A3 (en) 1990-08-16
JPS61212521A (ja) 1986-09-20
US4721720B1 (https=) 1992-06-30
HK77593A (en) 1993-08-06
EP0405617A3 (en) 1992-11-25
SG61693G (en) 1993-07-09
US4851407A (en) 1989-07-25
DE3689974T2 (de) 1994-11-03
DE385517T1 (de) 1991-07-25
EP0385517A3 (en) 1990-10-31
JPH05310734A (ja) 1993-11-22
JPH0748372A (ja) 1995-02-21
JPH0720863B2 (ja) 1995-03-08
DE3688296D1 (de) 1993-05-19
EP0385517A2 (en) 1990-09-05
JPH0555484B2 (https=) 1993-08-17
CY1727A (en) 1994-05-06
EP0405617A2 (en) 1991-01-02

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